ライフサイエンスコーパス: subset

1 s on Notch1, while Radical Fringe modified a subset.

2 r drug effectiveness in only a small patient subset.

3 l bioactivity fingerprints of a small kinase subset.

4 inct expression patterns in naive and memory subsets.

5 f tissue-resident innate lymphoid cell (ILC) subsets.

6 agnosis with the addition of other AITL-like subsets.

7 rsal, human-enriched, and body site-enriched subsets.

8 rived, GM-CSF-instructed, nonconventional DC subsets.

9 ytokine environments and activated leukocyte subsets.

10 e how CD19 affects CNS recruitment of B cell subsets.

11 nases identified activation status of B-cell subsets.

12 cells derived from different individuals or subsets.

13 sons and contrasts between different disease subsets.

14 ies to deliver vaccine components to skin DC subsets.

15 ssive function of Foxp3-expressing Treg cell subsets.

16 are functionally analogous to diverse T cell subsets.

17 ments of the lattice nodes by centring image subsets about the lattice intersections.

18 (ILCs) have been classified into "functional subsets" according to their transcription factor and cyt

19 show that SCARF-1 contributes to lymphocyte subset adhesion to primary human HSEC and could play an

20 n of individually sorted CAR-modified T cell subsets after activation with CD3 and CD28 Abs (CD3/28),

21 Subset analyses evaluating histology, chemotherapy regim

22 Cell subset analysis showed that VMP and adjacent mesenchyme

23 Subset analysis suggests that prior studies may have bee

24 ares the SLAMF7(-/low) fraction in each cell subset and preserves functional lymphocytes, including v

25 integrates the activities of distinct T-cell subsets and by definition is dynamic and responsive to a

26 and is shared by all preimmune murine B cell subsets and CD27- human B cells.

27 nd correlated to the presence of immune cell subsets and cytokine responses throughout the course of

28 between MBCs and naive B cells and among MBC subsets and how this leads to memory responses.

29 ly released by different human CD4(+) T cell subsets and started to unveil the potential use of their

30 s, bone marrow, CSF, circulating CD4+ T cell subsets, and plasma.

31 nalysis of Intracellular iMMUnolabelled cell Subsets) approach, we now compare protein abundance and

32 Invariant NKT (iNKT) cell functional subsets are defined by key transcription factors and out

33 All ILC subsets are functionally competent in vitro, and are suf

34 Moreover, these subsets are not fixed in lineage differentiation but can

35 lic programs of functionally distinct T cell subsets are tailored to their immunologic activities.

36 hese neurons are heterogeneous, and distinct subsets are thought to regulate different behaviors.

37 These cells can be subdivided into two major subsets based on the expression of the adhesion G protei

38 These studies suggest that a discrete DC subset both expands Tregs and suppresses CD8 T cells to

39 In blood cellular subsets both IL12p35 and EBV-induced gene protein 3 (EBI

40 cs and structure of murine CD4 T cell memory subsets by measuring the rates of influx of new cells an

41 ificantly, whereas the anti-inflammatory Th2 subset (CCR3(+)) was increased after DMF treatment.

42 ts (PD-L1, PD-1, LAG-3) and immune cell (IC) subsets (CD3, CD4, CD8, CD68).

43 the T cell compartment, inhibiting all cell subsets (CD4, CD8, WC-1, and gammadelta T cell receptor

44 tion of LCs in vivo, without altering the DC subset composition in the skin, we have generated transg

45 analysis of the splenic transitional B cell subsets demonstrated that MZ B cell development was bloc

46 e, or after reconstitution into the relevant subset-depleted population.

47 naling downstream of PD-1 in purified T cell subsets did not correlate with PD-1 surface expression b

48 organ donor tissue resource, we analyzed cDC subset distribution, maturation, and migration in mucosa

49 ve transfer of the CD103(+)alpha4beta7(high) subsets enhanced Th1/Th17 T cell generation and accumula

50 ong IL-10 increase, (ii) CD73(+)Foxp3(+)Treg subset expansion, and (iii) specific correlations betwee

51 images were reconstructed using both ordered-subset expectation maximization and Q.Clear (block-seque

52 ction of ZIKV antigen in a defined leukocyte subset from patients' whole-blood specimens.

53 ession of GCR were determined in lymphocytes subsets from cultured blood using flow cytometry.

54 , homeostasis, and functions of distinct IEL subsets has recently been provided.

55 serve as a marker of a pathogenic neutrophil subset in patients with septic shock.

56 tent of induction of the inflammatory T cell subset in vitro that mainly drives lesions, but not regu

57 brotic function of hepatic and peripheral NK subsets in 43 HBV-LC patients.

58 T cells subsets in blood, spleen and lymph nodes were detected d

59 terization and unbiased analysis of human DC subsets in blood, tonsil, spleen, and skin.

60 t tumor, but the role of human CD4(+) T cell subsets in cancer immunotherapy remains ill-defined.

61 elta5G virus infected distinct CD4(+) T cell subsets in SLOs and the small intestine, respectively (C

62 T-cell subsets in T-cell receptor beta knockout mice were recon

63 nction of Roquin was examined in immune cell subsets in the absence of autoimmune complications.

64 ed microchemotaxis assays on purified immune subsets including human pan-T cells, CD4(+) T cells, CD8

65 elow 10 nM in B-cell precursor ALL (BCP-ALL) subsets, including MLL-AF4 and TCF3-HLF ALL, and in some

66 Two major MDSC subsets, including monocytic MDSC and granulocytic MDSC,

67 At T0, the frequencies of CD4 T cell subsets, including peripheral T follicular helper (pTfh)

68 Various T-cell subsets, including Th2/Th22 cells, are increased in lesi

69 lls can differentiate into multiple effector subsets, including ThCTL that mediate MHC class II-restr

70 gate clonal relationships of various NK-cell subsets, including the adaptive population, by taking ad

71 Selective labeling of blood monocyte subsets indicates that non-classical monocytes are biase

72 rograms are preserved during cytokine-driven subset interconversion of human memory CD8 T cells.

73 reatment alters the interplay of immune cell subsets involved in antiviral humoral immunity.

74 ed how the differentiation into the NKT cell subsets is regulated.

75 Characterisation of M1 and M2 subsets is usually carried out by quantification of mult

76 In this patient subset, LA strain (area under the curve 0.73) and LA vol

77 Two distinct monocyte (Mo)/macrophage (Mp) subsets (Ly6C(low) and Ly6C(high)) orchestrate cardiac r

78 round 1 year, whereas most memory lymphocyte subsets more gradually increased during the first 4 year

79 n tested for expression in other immune cell subsets, MOSPD2 was apparent also, though less abundantl

80 A subset of 10 PCPs that were used within 6 h of urine col

81 veloped after analysis of image quality of a subset of 111 CT examinations to validate image quality

82 hird of the entire US population to create a subset of 128,989 families (481,657 unique individuals).

83 A subset of 224 eyes (123 female participants and 101 male

84 n), as well as 766 dermoscopic images from a subset of 30 patients (mean age, 40 years [range, 21-75

85 "fingerprint" and conservatively identify a subset of 312 surficial samples consistent with contamin

86 Furthermore, a subset of 34 DMRs related to impaired oxidative stress,

87 We analyzed serum samples from a subset of 47 children who had received a JE-CV booster a

88 Among a subset of 516 MSM who had at least 3 clinic visits, ther

89 skeletal-related events per year), and, in a subset of 553 patients, suppression of bone turnover (as

90 supine position on 58 eyes and upright on a subset of 8 eyes.

91 en depressed individuals and controls in the subset of 8590 UK Biobank Imaging study participants who

92 In a predefined numerical subset of all of the infants recruited to the study (n=4

93 uctuation tests typically investigate only a subset of all possible single nucleotide mutations.

94 In contrast, in a subset of animals ( approximately 33%), a delayed viral

95 findings from human cortex by identifying a subset of aromatase neurons as putative inhibitory inter

96 earning phase participants were exposed to a subset of auditory-visual combinations.

97 sed by mutations in NFKB1 and suggest that a subset of autoinflammatory diseases, such as Behcet dise

98 ignaling can drive an oncogenic program in a subset of basal breast cancers.

99 relationships are driven predominantly by a subset of brain regions comprising the somatomotor syste

100 ations to trigger optogenetic silencing of a subset of CA1 pyramidal neurons.

101 omere maintenance mechanism that occurs in a subset of cancers.

102 In a subset of cases (MS, n = 20; control, n = 10), expressio

103 prostate cancer (PC) can be aggressive in a subset of cases.

104 calcium signals to facilitate formation of a subset of CCPs, thus modulating its own signaling and en

105 A subset of CD8(+)RORgammat(+) T cells expressing a low le

106 hanism leading to lung function decline in a subset of children with asthma.

107 jury has been described, but whether it is a subset of classic calciphylaxis or a different entity re

108 We demonstrate that REEP6 is detected in a subset of Clathrin-coated vesicles and interacts with th

109 enzyme, is amplified and overexpressed in a subset of common types of cancer, including ovarian canc

110 with ER and blocks the interaction between a subset of coregulators with both native and mutant forms

111 nnels restrict the rate of exocytosis from a subset of cortical synaptic terminals within the EC and

112 preferentially expressed by the CD8alpha(+) subset of dendritic cells (CD8alpha(+) DCs) and is invol

113 dine pulse-chase experiment and found that a subset of ependymal layer cells (ELCs) were label-retain

114 For a subset of ESS3 variants, we show that specificity is det

115 s revealed the differential recruitment of a subset of expressed miRNAs and isoforms of miRNAs (isomi

116 Gene expression profiling revealed a subset of Forkhead box (Fox) genes that are regulated by

117 Only a subset of functions deregulated in initial tumors was si

118 Here we demonstrate that a subset of GABAergic chandelier cells (ChCs) in the preli

119 etabolic modeling markers, but less so for a subset of genes associated with mitochondrial respiratio

120 instability in the genetic architecture of a subset of genes could lead to widespread effects on the

121 K9ac increases the pol II pausing index on a subset of genes in HeLa cells.

122 Unexpectedly, we identify a subset of genes that adopted increased or de novo rhythm

123 homolog 1 (Ascl1) protein regulates a large subset of genes that leads neuronal progenitor cells to

124 majority of transcription units, while on a subset of genes, including rRNA and CRISPR loci, Spt4/5

125 Liverpool in 2010 and identified a specific subset of genes, which could have allowed this novel emm

126 ling DNA methyltransferase 3B to methylate a subset of genes.

127 s were all informative in distinguishing the subset of genetic variants more likely to have functiona

128 lk H3K4 methylation in ESCs; instead, only a subset of genomic loci exhibited reduction in H3K4me3 in

129 tions in human accelerated regions (HARs), a subset of genomic regulatory elements showing accelerate

130 anBP6 locus on chromosome 9p were found in a subset of glioblastoma (GBM) and silencing of RanBP6 pro

131 c dysregulation drives tumor initiation in a subset of glioblastomas harboring isocitrate dehydrogena

132 NKT cells represent a small subset of glycolipid-recognizing T cells that are heavil

133 ed in HIV progressors, we found that a small subset of gp120-specific interleukin-21 (IL-21)-secretin

134 nd colleagues report the identification of a subset of gynecological cancers with repressed expressio

135 d find a role for HSF1 in the induction of a subset of heat shock-induced readthrough transcripts.

136 lue of identifying AGTR1 overexpression in a subset of HER2-negative breast cancers, and they provide

137 In a subset of high viremic patients harboring R5 tropic HIV,

138 rovement Program (2000-2014) who underwent a subset of high-mortality inpatient general, vascular, or

139 on programs are often chosen randomly from a subset of high-quality genes that ideally represent the

140 We then correlated the imaging findings in a subset of HIV- subjects (n = 17) to CSF levels of neurof

141 A subset of HIV-infected individuals termed elite controll

142 ts PPXY L-domain motif to recruit a specific subset of host proteins containing one or more modular W

143 NEK6 was overexpressed in a subset of human prostate cancers.

144 sponses can be suppressed by a newly defined subset of ILCs with regulatory function.

145 stimulation of binding antibodies and, in a subset of immunized animals, in the induction of detecta

146 on of invariant NKT (iNKT) cells or a unique subset of innate-like CD1d-independent T cells.

147 Specifically, a subset of ipRGCs, comprising 200 cells and which projec

148 zymatic activity of JMJD6 was required for a subset of JMJD6-regulated splicing, and JMJD6-mediated l

149 -methylcytosine in the prophase nucleus of a subset of KIT(+) progenitors during mitosis.

150 rtion of inputs or coactivation of a smaller subset of local dendrodendritic inputs with coincidence

151 that ethanol decreased the firing of a large subset of low-frequency neurons.

152 to determine risk of malignancy and define a subset of low-risk BD-IPMNs.

153 engagement among all patients as well as the subset of LTFU patients who were alive, contacted in per

154 is issue of Cell, Hulsmans et al. identify a subset of macrophages residing within the cardiac conduc

155 c moment at 60 T might suggest that only one subset of magnetic moments has aligned along the field d

156 ymphoid cells, granulosa cell tumours, and a subset of malignant melanoma and thyroid cancers.

157 gether required for the differentiation of a subset of medial ganglionic eminence (MGE)-derived neuro

158 An important subset of membrane proteins have globular, cofactor-cont

159 In contrast, a subset of mice we term resilient only display anxiety-li

160 esulted in paralysis and pathology in only a subset of mice, whereas soluble Delta71-82 alphaS, human

161 n in the cortex of mice, where we identify a subset of mRNAs that are translated in dendrites by neur

162 r209 on eIF4E regulates the translation of a subset of mRNAs.

163 response may contribute to pathogenesis in a subset of neurodegenerative disorders.

164 hen we perform a sensitivity analysis in the subset of never-smokers, and these two probes are known

165 K(+) channel pore-forming subunit Kv4.3 in a subset of nociceptors to selectively inhibit mechanical

166 pore-forming subunit Kv4.3 is expressed in a subset of nonpeptidergic nociceptors within the dorsal r

167 Finally, we identify a small subset of NPF-expressing neurons located in the dorsomed

168 etrotransposon transcripts must identify the subset of nuclei that will be transmitted to offspring.

169 of the RNA that forms a T-loop module and a subset of nucleotides in the cobalamin-binding pocket.

170 In a subset of odor combinations, this history-dependent proc

171 rmation on AED exposure was available in the subset of offspring from July 1, 2005, to December 31, 2

172 DC66 exerts its function via regulation of a subset of oncogenes, and knockdown of circCCDC66 inhibit

173 rgans without the benefit of identifying the subset of organs with demonstrable proclivity to transmi

174 lish a repressive chromatin environment at a subset of origins, which primes them for late replicatio

175 o necessary for the transcription of a large subset of other IRF2-dependent interferon-regulated gene

176 Kyriacou et al. manually annotated a subset of our recordings and reported that two strains d

177 rtaking cognitive tests, a randomly selected subset of our sample was asked to recall emotions of anx

178 In the second step, in the subset of participants with DLPFC DNA methylation data (

179 In the third step, in the subset of participants with DLPFC RNA sequencing data (n

180 However, in a subset of patients aged 40 to 64 years, we found a sligh

181 ovided dramatic clinical benefit, but only a subset of patients exhibit clear and durable responses,

182 we used a statistical algorithm to select a subset of patients from this control cohort who were mat

183 effectively identify a substantial low-risk subset of patients possibly safe for early discharge wit

184 Notably, in the subset of patients who had received three or fewer prior

185 A subset of patients with early onset formed hallucination

186 xin type 9 (PCSK9) inhibitor evolocumab in a subset of patients with homozygous familial hypercholest

187 for the pharmacokinetic analysis included a subset of patients with rich pharmacokinetic samples fro

188 althy controls are conspicuously absent in a subset of patients with undiagnosed bleeding disorders,

189 ed bisulfite sequencing was performed with a subset of placentas, cord blood samples, and buccal samp

190 clusion, BRAF fusions define a new molecular subset of PMM that can be targeted therapeutically by th

191 st and mammalian cell membranes, including a subset of previously uncharacterized Legionella effector

192 cific and prevalent interaction with a large subset of primary microRNAs (pri-miRNAs) in mammalian ce

193 Following uncontrolled proliferation, a subset of primary tumour cells acquires additional trait

194 During meiotic recombination, a subset of programmed DNA double-strand breaks (DSBs) are

195 rin-dependent adhesion, NADPH oxidase, and a subset of protein kinases.

196 hway selectively controls the abundance of a subset of proteins.

197 Overexpression of a specific subset of Rab GTPase-activating proteins (RabGAPs) inhib

198 . show that interferon gamma production by a subset of regulatory T cells in the tumor microenvironme

199 hlorophyll-A concentrations from an external subset of river water samples (r(2) = 0.41; p < 0.0001;

200 Although a subset of sarcomas appears inflamed and responsive to im

201 to hair follicles (HFs), which house a major subset of skin SCs (HFSCs).

202 Here we show that a subset of SLC25A46 interacts with mitochondrial dynamics

203 Here we identified a subset of spinal interneurons, labeled by gastrin-releas

204 In a subset of stress-responsive genes in humans, Elongin con

205 es still relied on stress induction, another subset of stress-responsive genes was constitutively exp

206 al DNA methylation was found in only a small subset of symbiotic nodule-specific genes, including mor

207 cells are a recently discovered, innate-like subset of T cells with cytotoxic function, the role of w

208 g for potential confounders collected from a subset of the cohort members.

209 A subset of the genes adjacent to SNP hotspots showed stat

210 f natural protein sequences, through which a subset of the native side chains is displayed on an unna

211 e tag induces a strong population shift in a subset of the original Abeta42 structural sub-population

212 PFASs were not associated with CRP in the subset of the population with available data (n=640).

213 Thus, TAC fractions contain a specific subset of the processed chloroplast transcriptome.

214 n regardless of attentional task, although a subset of the responses is modulated similarly to prefro

215 stimulus sequence is recreated after only a subset of the visual input is provided.

216 ystem using fMRI are primarily confined to a subset of the visual system (high-level vision: faces, s

217 activation of naive T cells and polarized a subset of these cells into CD4+CD25+FoxP3+ regulatory T

218 Additionally, a subset of these clusters of ethylene-responsive transcri

219 lar to TULP3 and determines trafficking of a subset of these GPCRs to neuronal cilia.

220 A subset of these is also activated by the closely related

221 ations in FOXI1 can explain the disease in a subset of these patients.

222 while RNA is effective in supporting only a subset of these reactions.

223 -Man alters the peripheral localization of a subset of these regions and alleviates repression of som

224 We demonstrate that a subset of these SSPs can enter L. bicolor hyphae, locali

225 the atrial and ventricular gene sets, and a subset of these was found to cooperate with MEF2A.

226 The guaianolides, a major subset of this group, have been intensely investigated f

227 rating CD8(+) T cells represent an activated subset of those found in the periphery, having a residen

228 dorsal raphe nucleus and defined a discrete subset of transcripts expressed in these projecting neur

229 Here we describe a subset of tumor-infiltrating CD8(+) T cells marked by hi

230 mote cancer by remotely supplying a distinct subset of tumor-infiltrating SiglecF(high) neutrophils,

231 cause nearly every cervical carcinoma and a subset of tumors in the oropharyngeal tract.

232 ment via activation of Notch signalling in a subset of tumour cells, and the presence of these cells

233 cterization of the memory-precursor effector subset of virus-specific CD8 T cells transferred into an

234 st show that simple light steps can excite a subset of VPM neurons.

235 cteristics of percolation clusters formed by subsets of atoms, which can have important consequences

236 ls and was later found to be present on some subsets of B cells in humans; however, whether CD6 plays

237 Two subsets of blood monocytes are commonly described in mic

238 c temporal lobe epilepsy to demonstrate that subsets of cells discharge in a highly stereotypical seq

239 anthropogenic communities are not diminished subsets of contemporary natural communities.

240 the methods were found to predict different subsets of driver genes, we propose a novel consensus-ba

241 naive CD4 T cells into functionally distinct subsets of effector T cells (T helper 1 (TH1), TH2, and

242 population in addition to engaging specific subsets of exhausted-like CD8 T cells.

243 hown to control the transcription of defined subsets of genes in various cell systems.

244 mRNAs to heavy polysomes and translation of subsets of genes.

245 Facility assessment revealed that subsets of laboratories that claim biosafety level 1, 2,

246 y also depend on the degradation of specific subsets of mRNA.

247 t monocytic (mMDSC) and granulocytic (gMDSC) subsets of myeloid-derived suppressor cells infiltrate i

248 heir expression patterns in small and unique subsets of neurons from diverse brain regions.

249 e contributes to overactive Wnt signaling in subsets of pancreatic, ovarian, gastric, and colorectal

250 They are also used in the treatment of subsets of patients with heart failure and pulmonary hyp

251 Since only subsets of Phe/Gly motifs, particularly those within Nup

252 -regulatory modules (TRMs), which consist of subsets of preferentially and coordinately corecruited T

253 distinct binding poses and engage different subsets of residues, despite sharing a common morphinan

254 ts that are enriched or depleted from select subsets of ribosomes within embryonic stem cells.

255 ends in taxonomic similarity among different subsets of species nullified each other, producing a net

256 Brain stimulation has identified two central subsets of stimulation sites with motivational relevance

257 769 genes were differentially required in subsets of these cell lines at a threshold of six SDs fr

258 Substantial subsets of these genes exhibited altered expression in n

259 ibody in vivo in the absence of other T-cell subsets or even when TH2 cell functions were severely co

260 l types represent truly different neutrophil subsets or reflect changes induced by lipopolysaccharide

261 with regard to dynamics of the memory B cell subsets point to their role in the pathogenesis of HIV/S

262 Intriguingly, the latter subset predominates in many patients and tumor models, a

263 nsistent with events occurring in population subsets rather than the full claustral cell population.

264 ate random combinations of inputs but that a subset receives stereotyped inputs from single projectio

265 lower restriction factor expression in this subset relative to peripheral blood prior to infection.

266 quiring cells from healthy human lung, these subsets remain poorly characterized transcriptionally an

267 improve the treatment of this breast cancer subset.Significance: These findings offer a mechanistic

268 lts offer a promising path for developing DC subset-specific immunotherapies that cannot be provided

269 ed in HIV-associated tumors for any cellular subset studied.

270 Th subsets Th1 (CXCR3(+)), Th17 (CCR6(+)), and particularly

271 and the nonclassical blood resident monocyte subset that patrols the intraluminal side of the endothe

272 are a newly defined regulatory T cell (Treg) subset that suppresses follicular helper T cell-mediated

273 tion and communication among intermingled PC subsets that contribute to separate brain networks remai

274 Key discoveries include the cellular subsets that function as potential sources of alloantige

275 ges in tumor-infiltrating myeloid cell (TIM) subsets that likely compromise anti-tumor T cell immunit

276 dent phenotypic changes in blood immune cell subsets that occur following trauma, including induction

277 lymphocytes differentiate into heterogeneous subsets that together provide immediate and durable prot

278 human cancers might help to identify tumour subsets that undergo cell death and tumour regression up

279 study the responsiveness of different T cell subsets, that is, naive, effector, and memory T cells.

280 moted the expansion of a GM-CSF(+) Th17 cell subset, thereby enhancing its encephalitogenic potential

281 IgE(+) cells, the capacity of tonsil B-cell subsets to generate IgE(+) PCs and the class switching p

282 To investigate hepatic T-cell subsets upon hypercholesterolemia.

283 ro and ex-vivo susceptibility profiles for a subset using piperaquine survival assays.

284 ance phenotype and in a second experiment, a subset was chosen to compare fitness (fecundity and surv

285 enrichment analysis revealed that each gene subset was enriched with different biological processes.

286 uarters of subsequent breast cancers in each subset were ductal carcinoma in situ or stage I.

287 PC subsets were lower in number in HF and after adjustment

288 All subsets were more efficient at internalizing S. aureus a

289 B-cell subsets were quantified by flow cytometry; annexin-V sta

290 adoptive transfer with CD4+ or CD8+ T-cells subsets were reconstituted in T-cell receptor beta knock

291 E-cadherin, and produced heterogeneous cell subsets whose phenotype and migration were dependent ( a

292 rred to as BCR-ABL1-like ALL, is a high-risk subset with a gene expression profile that shares signif

293 reened on GGTA1/CMAH/B4GalNT2 KO cells and a subset with elevated binding was evaluated further.

294 Similarly, in the subset with KIT exon 11 deletion mutations, higher-than-

295 0.41% of the entire cohort and 7.56% of the subset with metastatic disease to any site.

296 Dendritic cell (DC) subsets with biased capacity for CD4(+) and CD8(+) T cel

297 Multiple memory CD8(+) T-cell subsets with distinct functional and homing characterist

298 exhibit that CD26 identifies three T helper subsets with distinct immunological properties in both h

299 generate discrete gammadelta T cell effector subsets with distinctive molecular signatures.

300 ively, these findings identify CD4(+) T cell subsets with properties critical for improving cancer im