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1 resent in actively transcribing regions in a substantial amount.
2 particular, six of the NFD monkeys exhibited substantial amounts (-1.81 to -9.00 D) of relative myopi
3                           Although we know a substantial amount about how the brain represents pain a
4 ultimately routed to the melanosome, we find substantial amounts accessible to our antibodies at the
5 n high throughput technologies have provided substantial amounts and diverse types of genomic data th
6 -D170V, but not D1-D170E, were prone to form substantial amounts ( approximately 40-50%) of inactive
7 ighest levels are in the nervous system, but substantial amounts are also present in peripheral organ
8 o deviate from the continuum prediction by a substantial amount, as much as 20% in our system.
9 ition, has been previously shown to occur in substantial amounts both in tissues under inflammatory s
10 FN-dependent chemokine IP-10 was produced in substantial amounts by pDCs in response to WNV(Vero) but
11 lated beta4 is found dissociated from HDs, a substantial amount can be associated with HDs near the c
12 nd beta(2)K274C change their fluorescence by substantial amounts during channel blockade by pentobarb
13  Many microalgae have the ability to produce substantial amounts (e.g. 20-50% dry cell weight) of tri
14 ducing the number of candidate formulas by a substantial amount, even when no bromine or chlorine ato
15 eu5Gc antibodies can be affinity-purified in substantial amounts from clinically approved intravenous
16 dentified epigenetic modification present in substantial amounts in certain mammalian cell types.
17 , and none of these 10 proteins was found in substantial amounts in other subcellular fractions.
18      Here, we show that Akt3 is expressed in substantial amounts in platelets.
19 )-beta,beta-carotene-3,3'-diol] are found in substantial amounts in the retina of the Japanese quail
20                  The genomic methods provide substantial amount information on global gene expression
21 etected on marginal zone (MZ) B cells, and a substantial amount of Ag was detected in splenic follicl
22 dication for anorectal testing, along with a substantial amount of anorectal-only infections.
23  5817 novel transcription units, including a substantial amount of antisense gene transcription, and
24                                            A substantial amount of autocorrelation was noted, suggest
25 these SNPs is labor-intensive and requires a substantial amount of automation.
26                                            A substantial amount of between-population variation in po
27 esional skin of patients with AD, produced a substantial amount of biofilm in vitro.
28 flows through their hosts and can comprise a substantial amount of biomass in many systems, whether e
29             Further analysis revealed that a substantial amount of both 14-3-3zeta and cyclin B1 accu
30 ed more than 15 years ago, in fact contain a substantial amount of carbohydrate.
31     In particular, the nanotubes can carry a substantial amount of cargo (100 times more than a monoc
32 periments also indicate that skin contains a substantial amount of catalase, which is sufficient to d
33 ns had less CCK 8 than wild-type, although a substantial amount of CCK was still present.
34                    Those reagents generate a substantial amount of chemical waste and lack recyclabil
35 ammatory cytokines; however, they secreted a substantial amount of chemoattractants for monocytes (MC
36 s that their locomotor repertoire included a substantial amount of climbing.
37 oss 15 of the 17 linkage groups, there was a substantial amount of clustering among QTL controlling d
38 ebastes) larvae and pelagic juveniles to the substantial amount of complex hardscape habitat created
39                               We find that a substantial amount of COPI is associated with Golgi memb
40               Genomic drift also generates a substantial amount of copy-number variation in chemosens
41                                            A substantial amount of data concerning the pathogenesis o
42                                  Despite the substantial amount of data consistent with this idea, a
43             Our hypothesis is supported by a substantial amount of data gathered from a range of diff
44    Seasonal autoregressive models captured a substantial amount of dengue variability, but better mod
45  In spite of a nuclear targeting sequence, a substantial amount of dual-specificity tyrosine phosphor
46 that contains sufficient charge to extract a substantial amount of energy from the high-gradient, non
47 ated electrons was insufficient to extract a substantial amount of energy from the wake.
48       The results suggest that 1) there is a substantial amount of error in individuals' self-assessm
49 and reconversion to substrate occur before a substantial amount of ethane is released.
50             During the last several years, a substantial amount of evidence from animal as well as hu
51  sharing the same set of ligands, there is a substantial amount of evidence that the N- and C-lobes a
52                                   We found a substantial amount of evolutionary complexity in Bd with
53 are rich in proteins but they also contain a substantial amount of free amino acids, especially argin
54  Because of confinement in two dimensions, a substantial amount of FRET is generated by energy transf
55                                            A substantial amount of frictional dissipation in the atmo
56 nctional studies in cell lines may uncover a substantial amount of genetic variation that affects gen
57 s, copy number variants (CNVs) account for a substantial amount of genetic variation.
58                                            A substantial amount of heme-bound mPGES2 was detected in
59                          Although reduced, a substantial amount of histone acetylation and H3 lysine
60 nt of direct charges, it accounts for a very substantial amount of indirect or downstream billing for
61 ethod that is nondestructive, and provides a substantial amount of information about the sample, is i
62 data and/or standard materials, leading to a substantial amount of information being inaccessible.
63 g activity of theta-driving neurons shares a substantial amount of information with the theta wave re
64  curing a specific condition, there exists a substantial amount of information within published syste
65 om grazing incidence x-ray measurements show substantial amount of inter-diffusion of Ga and In withi
66             Cancer metabolism has received a substantial amount of interest over the past decade.
67 on of these innate immunity pathways possess substantial amount of intrinsic disorder.
68 ic sequence or 86% of each gene, including a substantial amount of introns, all exons, and 1.3 kb ups
69 rket success of oncology drugs has induced a substantial amount of investment in oncology drug develo
70 ith type 1 diabetes; however, the need for a substantial amount of islets and, in many instances, rep
71     The large-for-size organ provides a more substantial amount of liver tissue to each of the adult
72          HPLC analysis indicated presence of substantial amount of lycopene in soluble fraction which
73 caffolds in unsupplemented medium produced a substantial amount of mature elastin within 3 wk and the
74  the polypeptide is assembled and requires a substantial amount of metabolic energy.
75                                          The substantial amount of metabolically active lineages foun
76 al human cell lines tested promptly export a substantial amount of miRNAs into the culture medium and
77 unique technical considerations, including a substantial amount of missing data and a nonuniform dist
78  biopsies was not available, and there was a substantial amount of missing data on cardiovascular ris
79 ugh the primary efficacy endpoint was met, a substantial amount of missing data was observed.
80          Frequently, however, MSAs contain a substantial amount of missing data.
81                                            A substantial amount of mitochondrial energy is required f
82                At pH 2.0, we also observed a substantial amount of monomers in the system, which do n
83                     Unexpectedly, we found a substantial amount of murine DNA in our samples that inc
84 he extracellular membrane surface contains a substantial amount of negatively charged sialic acid res
85 e plasma membrane and the endosomes, where a substantial amount of NEU3 is stored with low enzymatic
86                               Furthermore, a substantial amount of new AChRs was detected at these AD
87 increased research activity in this field, a substantial amount of new data--especially related to ma
88 pha-cat is well appreciated, cells contain a substantial amount of nonjunctional alpha-cat that may b
89                                            A substantial amount of organismal complexity is thought t
90 he ophthalmology of MS is highlighted by the substantial amount of original research presented at rec
91 of the world's largest genome centers, and a substantial amount of our sequencing is performed with '
92              Mammography screening entails a substantial amount of overdiagnosis.
93         During irradiation of melanosomes, a substantial amount of oxygen was converted into hydrogen
94 t role in evasion of acquired Abs and that a substantial amount of phenotypic diversity results from
95                                   There is a substantial amount of published work describing how to h
96 rate that, for any fiber diffraction data, a substantial amount of refinement error is due to long-ra
97                                   We found a substantial amount of remaining NPY-ir fibers, likely em
98                                            A substantial amount of research efforts have been devoted
99 xposed to cat odor in their home cage, and a substantial amount of risk assessment behavior was prese
100  seminal exosome (SE) preparations contain a substantial amount of RNA from 20 to 100 nucleotides (nt
101                                            A substantial amount of scientific and clinical evidence h
102             This indicates the emission of a substantial amount of semivolatile material during the U
103 search in public pathway data can identify a substantial amount of signaling relations that do not ex
104   Luciferase-positive donors revealed that a substantial amount of smooth muscle cells within the obl
105             On entering the nematic phase, a substantial amount of spectral weight is transferred fro
106                                   Although a substantial amount of structural data exist for HAH1 and
107 ine (Pinus sylvestris), is able to oxidize a substantial amount of structural Fe(II) in biotite.
108   Therefore, our new findings suggest that a substantial amount of surface-expressed Na/K-ATPase, at
109                                            A substantial amount of surfactant was released into ethan
110 vel variation in osmolar therapy use and the substantial amount of sustained osmolar therapy without
111 sions failed to associate, indicating that a substantial amount of the central region of the FliJ seq
112  Bayesian diet-mixing models revealed that a substantial amount of the crows' protein and lipid intak
113     Local unemployment rates accounted for a substantial amount of the heterogeneity in IPS effective
114                  We also demonstrated that a substantial amount of the hypersecreted insulin was degr
115            Recent analyses have found that a substantial amount of the Neandertal genome persists in
116 cer-derived small RNAs produced by plants: A substantial amount of the total small RNA abundance and
117                   The results suggest that a substantial amount of the variation in beliefs related t
118 main persistently infected and account for a substantial amount of the viral DNA in peripheral blood
119                                            A substantial amount of Ti is leached into blood from thes
120                                   However, a substantial amount of time in all three treatments was s
121       Olive mill wastewater (OMW) contains a substantial amount of valuable antioxidant phenols that
122 that microarray-based measurements exhibit a substantial amount of variability due to a number of pos
123 r variance, these novel findings show that a substantial amount of variance in white matter integrity
124 nadditive genetic influences accounted for a substantial amount of variation in the developmental cou
125                      These sequences carry a substantial amount of variation that may or may be not r
126                                       Yet, a substantial amount of Vp3 was present in anti-Vp1 immune
127 nds for amide reductions, and apart from the substantial amount of waste generated using these method
128                 Over the past 10-15 years, a substantial amount of work has been done by the scientif
129                              The presence of substantial amount of zinc results in two distinctive en
130                     In the absence of FB(1), substantial amounts of 1-deoxySa are made and acylated t
131 quently, the RPE65 gene delivery resulted in substantial amounts of 11-cis retinal in Rpe65-/- mice.
132 s had a high 15-LOX2 expression and secreted substantial amounts of 15(S)-hydroxyeicosatetraenoic aci
133 ene reaction adducts may be significant, but substantial amounts of 2-vinylbenzonitrile and 2-ethynyl
134       In addition to 5-methylcytosine (5mC), substantial amounts of 5-hydroxymethylcytosine (5hmC) al
135                             The discovery of substantial amounts of 5-hydroxymethylcytosine (5hmC), f
136                                    Recently, substantial amounts of 5-hydroxymethylcytosine (5hmC), m
137 age zygotes the paternal pronucleus contains substantial amounts of 5hmC but lacks 5mC.
138                             The isolation of substantial amounts of a hemicarcerand lacking one aceta
139 tions at appropriate cell densities produces substantial amounts of Abeta that appear both in cell ex
140 r studies show that all three promoters form substantial amounts of abortive products under all condi
141  based only on surrogate information secured substantial amounts of adaptive and neutral genetic vari
142 phases of iron-nickel and iron sulphide with substantial amounts of Al and Cu.
143 ave shown that some individuals can tolerate substantial amounts of Alzheimer's pathology in their br
144  As with other high-throughput technologies, substantial amounts of analytical data are generated.
145                      Although plants contain substantial amounts of arabinogalactan proteins (AGPs),
146 vealed that the newly formed FeS sequestered substantial amounts of As.
147  Consistently, isolated heterocysts released substantial amounts of beta-aspartyl-arginine.
148                             This can deliver substantial amounts of bioavailable iron and contribute
149 dothelial cells can be stimulated to secrete substantial amounts of blood group A and B antigens link
150 s suggest that adipose tissue can metabolize substantial amounts of branched chain amino acids (BCAAs
151 biotin and biotin analogs varied widely, but substantial amounts of BSO were detected in every sample
152  the ole loading AT domain, and gave rise to substantial amounts of C13-methylerythromycins, as predi
153  of the alloimmune response but also produce substantial amounts of C3.
154           If the ER response is overwhelmed, substantial amounts of calcium are released into the cyt
155                 We conclude that by shunting substantial amounts of carbohydrate into urine, SGLT2-me
156        Inland waters transport and transform substantial amounts of carbon and account for approximat
157 m this study suggest that rising CO2 can add substantial amounts of carbon to ecosystems through stim
158  a region of known high aerosol loading with substantial amounts of carbonaceous aerosols from a vari
159 ns from NHF were larger particles containing substantial amounts of CD63.
160 fringens, only binds to membranes containing substantial amounts of cholesterol.
161 f cisZOG1 and cisZOG2, and identification of substantial amounts of cis-isomers in maize tissues.
162  albumin in patients who continue to require substantial amounts of crystalloid to maintain adequate
163 s of endosomal and lysosomal C3 and CTSL and substantial amounts of CTSL-generated C3a.
164 the ability of the CD4(+) T cell to generate substantial amounts of cytokine.
165 n samples from SOFeX and IronEx II, we found substantial amounts of DA associated with Pseudo-nitzsch
166 nce can recover multiple filters but require substantial amounts of data, and recover an orthogonal b
167                        Because BcPh DEs form substantial amounts of deoxyadenosine adducts at dA, the
168                              The presence of substantial amounts of dicarboxylates in cuticular membr
169 r ancestors were exposed to (and adapted to) substantial amounts of dietary ethanol.
170  the catalytic hydrophenylation of ethylene, substantial amounts of diethylbenzenes are produced, and
171         The cornea and crystalline lens lost substantial amounts of dioptric power in this phase of g
172 l sequences of all 24 mutant subunits showed substantial amounts of disorder, leading to multiple C-t
173 high-throughput sequencing platforms require substantial amounts of DNA; both of these factors preclu
174 s of active AADC are sufficient to allow for substantial amounts of dopamine to be produced in model
175                                 We show that substantial amounts of endogenous Daxx and ATRX exist in
176  breast cancer cells that originally express substantial amounts of endogenous NPGPx increased their
177  pulses in free space are capable of gaining substantial amounts of energy that scale linearly with t
178 mpered by an inability to express and purify substantial amounts of enzyme.
179  to prepare O-linked glycopeptides result in substantial amounts of epimerization at the alpha positi
180  that is extensively nuclear in hepatocytes, substantial amounts of EWSR1 localize to the cytosol in
181                                              Substantial amounts of excimer formation are observed fo
182 -free algorithms rely on the accumulation of substantial amounts of experience to compute the value o
183 et layers, yet with a low hydrophobicity and substantial amounts of exposed mannan and chitin at the
184 al and cell extraction studies indicate that substantial amounts of FBPase were in the extracellular
185 chondria contained more NHHS Fe(II) ions and substantial amounts of Fe(III) nanoparticles.
186 to 8 m urea, accounting for the formation of substantial amounts of fibrils under such conditions.
187 6 M Gdn.HCl, accounting for the formation of substantial amounts of fibrils under such conditions.
188  showed that maize and wheat plants obtained substantial amounts of fixed nitrogen from the atmospher
189 er process would require the availability of substantial amounts of free NH2OH for chemical reactions
190 ast, PMs of PD-susceptible genotypes all had substantial amounts of fucosylated XyGs and weakly ME-HG
191 uced transcript is therefore translated, and substantial amounts of functional PGD(2) synthase accumu
192 demonstrate that adult humans do indeed have substantial amounts of functioning brown adipose tissue
193 mary tumor 4T1, which expresses and secretes substantial amounts of Gal1.
194  mycelium-supplemented bread still contained substantial amounts of gamma-aminobutyric acid and ergot
195 re not just permeable to O(2) but also store substantial amounts of gas.
196   Tunisian M. truncatula populations contain substantial amounts of genetic variation that is structu
197 s other than the liver and kidney to release substantial amounts of glucose into the mammalian blood
198 are associated with a rich matrix containing substantial amounts of glycosylated chondroitin sulfate
199 ntext of global warming through emissions of substantial amounts of greenhouse gases.
200 into excess NH3, and under these conditions, substantial amounts of HCHO, but no CH3OH, were detected
201 show that low energy phonons still transport substantial amounts of heat in these materials, despite
202                                     However, substantial amounts of heterogeneity may remain unaccoun
203  that transcriptomes of normal cells harbour substantial amounts of hierarchical structure.
204 and L. major-infected C57BL/6 mice exhibited substantial amounts of HIF-1alpha in acute cutaneous les
205 nd characterized transgenic rye synthesizing substantial amounts of high-molecular-weight glutenin su
206                                     However, substantial amounts of HR proteins exist in the cytoplas
207                                              Substantial amounts of human apoA-I existed in lipid-fre
208                    Vesta's regolith contains substantial amounts of hydrogen.
209 ly isolated human pDCs, these cells produced substantial amounts of IFN-alpha via TLR7 signaling when
210 e, these tolerized CD4 cells fail to express substantial amounts of IFN-gamma in response to antigeni
211 ive immune response results in production of substantial amounts of IFN-gamma in response to Mtb, the
212 in fractions from roasted walnuts maintained substantial amounts of IgG immunoreactivity (using anti-
213 lass, while PsaA-IL-2 and PsaA-IL-4 elicited substantial amounts of IgG2a in addition to IgG1.
214  fungi secreted minimal amounts of IL-12 but substantial amounts of IL-10 compared with mature DCs fr
215 erved that these T regulatory cells released substantial amounts of IL-10, produced IFN-gamma, failed
216 matory cytokines, whereas liver DCs produced substantial amounts of IL-10.
217 ication, while B cells spontaneously produce substantial amounts of infectious virus.
218 apses of human neurons can actually transfer substantial amounts of information during spike trains.
219 viral defense, which led to the secretion of substantial amounts of interferon-alpha (IFN-alpha).
220 ular Bok is IP3R bound in cells that express substantial amounts of IP3Rs.
221                              Monkey kola had substantial amounts of iron, zinc, and copper; the B-vit
222                             If this is true, substantial amounts of its decay product, (56)Fe, may st
223                   Migrating birds catabolize substantial amounts of lean tissue during flight which m
224 ils and monocytes/macrophages, which produce substantial amounts of local myeloperoxidase (MPO).
225 rrow product copolymer polydispersities, and substantial amounts of long-chain branching are observed
226 vaporate with atmospheric dilution, creating substantial amounts of low-volatility gas-phase material
227 d; these values indicate a source containing substantial amounts of mantle- or carbonate-derived carb
228 nd splenic dendritic cells (DCs) can secrete substantial amounts of mature IL-1beta upon stimulation
229 an sulfate (unfractionated heparin) released substantial amounts of MCP-1 from Darc.
230                   In contrast to Med12-like, substantial amounts of Med12 were detected in both Schwa
231                                     Notably, substantial amounts of methylation are targeted by Pho4-
232            Because cutaneous mouse MCs store substantial amounts of mMCP-6.heparin complexes in their
233                Techniques like HCD result in substantial amounts of modification losses, competing wi
234 ell lines, cancer cell lines often expressed substantial amounts of mRNA isoforms with shorter 3' unt
235 erventions per se are not likely to preserve substantial amounts of myocardium early after ischemic i
236 These findings show that AM fungi can obtain substantial amounts of N from decomposing organic materi
237 e, mitochondria-linked pathways can generate substantial amounts of NADPH and do so even when the pen
238 ed embryoid bodies metabolically incorporate substantial amounts of Neu5Gc under standard conditions.
239        By enzyme-linked immunosorbent assay, substantial amounts of NGF protein are also detected in
240 omise as functional models of nitrogenase as substantial amounts of NH3 are produced upon exposure to
241  Ammonia (NH3)-oxidizing bacteria (AOB) emit substantial amounts of nitric oxide (NO) and nitrous oxi
242 n legumes and Rhizobium bacteria can provide substantial amounts of nitrogen (N) and reduce the need
243 ed organic aerosol formation, and imply that substantial amounts of nitrogen is fixed as organic macr
244 MC leukemia patient revealed the presence of substantial amounts of non-functional forms of hRasGRP4
245 s, revealing unbiased sequence coverage with substantial amounts of nonredundant nuclear sequences fr
246                            While trees store substantial amounts of nonstructural carbon (NSC) for la
247         Interestingly, when expressed alone, substantial amounts of NS1 and NS2 localized to the nucl
248  Despite their large size and consumption of substantial amounts of nutrients, the ob/ob mice had onl
249                    The unexpected finding of substantial amounts of ornithine, the nonprotein amino a
250                        Grass lignins contain substantial amounts of p-coumarate (pCA) that acylate th
251 pens and Medicago sativa, do not contain any substantial amounts of PAs in leaves.
252                                              Substantial amounts of pentavalent organoarsenicals have
253                                              Substantial amounts of perivascular edema and inflammato
254  A constituents of P. gingivalis but contain substantial amounts of phosphorylated dihydroceramide li
255 x that forms in these cells does not contain substantial amounts of PKR, suggesting that the interact
256 es, and we recently showed that they contain substantial amounts of polyphosphate, which is secreted
257 mum L.) and many other plant species contain substantial amounts of polyunsaturated fatty acids (PUFA
258 w avenue for paleogenomics studies, allowing substantial amounts of population-level DNA sequence inf
259 ers to homodimers and homotrimers, can cause substantial amounts of protein to be trapped as intermed
260                                              Substantial amounts of proteins were produced, including
261        Our data demonstrate the retention of substantial amounts of ptDNA in mesophyll cells until le
262                         The incorporation of substantial amounts of pureed vegetables to reduce the E
263           We also found that Co-II generates substantial amounts of reactive oxygen species that incr
264              Most eukaryotic genomes contain substantial amounts of repetitive DNA organized in the f
265                        Kenya has experienced substantial amounts of reported cases of cholera during
266 eptor cell outer segment tips by RPE provide substantial amounts of retinal autoantigens for potentia
267 used for this purpose constitutively produce substantial amounts of RNA from a TATA-containing crypti
268 hough direct TFF of clarified lysate removed substantial amounts of RNA, the RNA levels left in the r
269 ved a capsid species that appears to contain substantial amounts of scaffolding protein as well as DN
270 e dataset from the Yellow River to show that substantial amounts of sediment eroded from Northeast Ti
271 rarily low mean spiking correlations despite substantial amounts of shared input.
272                                              Substantial amounts of spatial and temporal microarray e
273 loides is a yeast that naturally synthesizes substantial amounts of specialty chemicals and has been
274 anasal inoculation with B. anthracis spores, substantial amounts of spores could be recovered from th
275                      The results showed that substantial amounts of spores were taken up by lung epit
276 r, plants lacking both enzymes still degrade substantial amounts of starch.
277 luding tumor-associated fibroblasts, degrade substantial amounts of surrounding matrix by a mechanism
278 blood serum samples of RA patients contained substantial amounts of synoviocyte-derived soluble MICA,
279 on toothbrush head components can accumulate substantial amounts of TCS after brushing with TCS-formu
280 ition of 17 in cyclohexane under oxygen gave substantial amounts of tert-butyldimethylsilyl acetophen
281                            The production of substantial amounts of the 5-coordinate CO adduct upon a
282                                              Substantial amounts of the anti-substituted isoprostanes
283 s with small numbers of founders may contain substantial amounts of the evolvability found in nature,
284             Thus, hESC-CMs can remuscularize substantial amounts of the infarcted monkey heart.
285                  In prolonged starved cells, substantial amounts of the key gluconeogenic enzyme fruc
286  of the antioxidant resulted in formation of substantial amounts of the nonconjugated C-3 diene hydro
287 either of the cell lines was able to produce substantial amounts of the pre-S1-containing HDV particl
288 ow that TAMs isolated from human RCC produce substantial amounts of the proinflammatory chemokine CCL
289 itionally, VRP-infected DC cultures secreted substantial amounts of the proinflammatory cytokines IL-
290 D40-/- mice bearing Renca tumors resulted in substantial amounts of TNF-alpha and MCP-1 in the serum,
291                  Germinated grains contained substantial amounts of total phenolics with rye having s
292 od" of producing stable solutions containing substantial amounts of transitory enzyme intermediate co
293                                          The substantial amounts of trapped water in the graphite oxi
294                                 They produce substantial amounts of type I interferons (IFN) and inte
295                 Here, we show that there are substantial amounts of unanchored ubiquitin in protein a
296   Some cell lines carrying the CCE1 gene had substantial amounts of WT mtDNA suggesting that the enzy
297 with mutations Q84A, L87A, and L96A) secrete substantial amounts of Yops yet exhibit severe defects i
298  zinc trigger seizures and are neurotoxic if substantial amounts of zinc reenter the cells via ion ch
299 rough the phloem but was also transferred in substantial amounts to the apoplast, and presumably othe
300           Isoprene is made by some plants in substantial amounts, which affects atmospheric chemistry

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