ライフサイエンスコーパス: substantial difference

1 Substantial differences across countries and over time r

2 There are substantial differences across species in the organizati

3 (FEBS Lett 579[1], 259-64), we did not find substantial difference among the three variants accordin

4 We identified substantial differences among CA, AA, and AS populations

5 High-density mapping shows substantial differences among channels in ventricular sc

6 as stopping CO2 emissions entirely, but with substantial differences among countries, implying differ

7 We detected substantial differences among these factors.

8 vitro and in vivo Genomic comparisons showed substantial differences among three of the isolated clon

9 ), determined using gel shifts, displayed no substantial differences, and were of the same order as k

10 n the cell-attached configuration, whereas a substantial difference ( approximately 30%) is observed

11 Substantial differences are observed for the extent of o

12 For example, substantial differences are seen when selected cancers i

13 IMP-1 (Protein Data Bank entry 1UEA), we see substantial differences at the binding interface that pr

14 Our data indicate that there is no substantial difference between filaments formed in vivo

15 Overall the MAS NMR data indicate a substantial difference between the structure of the fibr

16 roscopic current kinetics also highlighted a substantial difference between the two sets of mutations

17 Our results demonstrate substantial differences between air and surface temperat

18 different F-protein antigenic sites revealed substantial differences between antibodies elicited by A

19 placements of spoIIQ and spoIVFA, suggesting substantial differences between bacilli and clostridia i

20 d modification studies of the BK S6 point to substantial differences between BK and Kv channels in th

21 ror estimations indicate the possibility for substantial differences between CA- and IA-based assessm

22 cted countries within the study period, with substantial differences between countries, ranging from

23 an represent as much as 35% of fixed N, with substantial differences between cultures using the Mo- a

24 This large study found no substantial differences between dietary methods and obse

25 amino acid sequence, there are in some cases substantial differences between genetic and antigenic di

26 Substantial differences between GLUT1, GLUT4, and GLUT8

27 Our results clearly demonstrate substantial differences between healthy and emphysematou

28 at were homologous between lineages revealed substantial differences between helices.

29 These results illustrate substantial differences between human tumors and many mo

30 sts that the mouse model accurately reflects substantial differences between immunities to these orga

31 en irreversible worker and queen castes, but substantial differences between nurses and forager subca

32 There were substantial differences between officially reported and

33 We also found substantial differences between our identified vertebrat

34 been little gene order evolution, there are substantial differences between poxviruses in terms of g

35 es may suffer from publication bias, whereby substantial differences between published and unpublishe

36 In conclusion, we found substantial differences between published IR indexes in

37 alysis of raw sequencing data and we observe substantial differences between recognition by Ago2 of R

38 Theory shows that coexistence requires substantial differences between species, but species-lev

39 Recent studies have demonstrated substantial differences between the brains of breeders a

40 We found substantial differences between the dose estimated by th

41 Although there are substantial differences between the magnetospheres of Ju

42 There were significant, consistent and substantial differences between the mature and immature

43 We found substantial differences between the stress responses of

44 This suggests that there may be substantial differences between the toxin-binding sites

45 mpus using diffusion imaging showed the most substantial differences between the two groups and was t

46 c activities of Chk1 and hCds1/Chk2 revealed substantial differences between the two Ser/Thr kinases.

47 Because of substantial differences between these 2 groups, propensi

48 Furthermore, substantial differences between trypanosomal TyrRS and h

49 inactivation of reovirus particles revealed substantial differences between virions and infectious s

50 mmalian DNA methyltransferase Dnmt3b reveals substantial differences both in the C-terminal helical r

51 teworthy that overall national trends masked substantial differences by place and by educational atta

52 ong conservation of Shaker family in plants, substantial differences can exist between the physiologi

53 gned to T = 3 plant RNA viruses but exhibits substantial differences compared with the insect-infecti

54 Substantial differences exist between county ischemic he

55 Whereas substantial differences exist between familial and spora

56 Substantial differences exist in the cognitive styles of

57 Although substantial differences existed between the two inhibito

58 Our analyses also show substantial difference for DRA genes between young and o

59 There was no substantial difference for the detection of calculi in t

60 IHME GBD estimates for South Africa revealed substantial differences for estimated deaths from all ca

61 h those of unliganded HMGCL and R41M reveals substantial differences for Mg(2+) coordination and posi

62 vel taxonomic group, metabolic rates exhibit substantial differences, for which diverse explanatory f

63 rs of these three classes of genes displayed substantial differences, highlighting the importance of

64 Substantial differences, however, were found both betwee

65 the NANSAID rofexocib with naproxen showed a substantial difference in acute myocardial infarction ri

66 line in serial repopulating capacity, but no substantial difference in apoptosis or levels of reactiv

67 However, images with a substantial difference in appearance violate this assump

68 Taken together, these data indicate that the substantial difference in Ca(2+) signals in fine distal

69 There is a substantial difference in cases identified by NLP compar

70 The origin of the substantial difference in deacylation rates for acyl-enz

71 formation, we also conclude that there is no substantial difference in effect of the 4 drugs on peopl

72 ctural and functional assays demonstrated no substantial difference in functional or structural avidi

73 ng traction force microscopy, we also find a substantial difference in growth cone traction force gen

74 Results No substantial difference in interobserver agreement was ob

75 equency (2850 cm(-1)) SRS imaging revealed a substantial difference in lipogenesis between the flucon

76 base interval in the class I D locus confers substantial difference in MCMV control phenotypes.

77 Irrespective of the length of dormancy a substantial difference in metabolite composition at each

78 No substantial difference in PFS or OS was observed between

79 ntical behaviour in magnitude, but engenders substantial difference in phase between transmitted left

80 and suggested a possible explanation for the substantial difference in reactivity between the t-Bu- a

81 o play an important role, accounting for the substantial difference in reactivity between triaryl and

82 However, there was a substantial difference in the ability of AZD0530 to inhi

83 There was no substantial difference in the accuracy of volume estimat

84 factors in other regions, combined with the substantial difference in the demand pattern for cooling

85 procedures, and second that there would be a substantial difference in the effectiveness of antibioti

86 ed by 6-fold relative to wild type without a substantial difference in the fidelity of 2'-dNMP incorp

87 is the largest reported to date and showed a substantial difference in the genetic causes of RP compa

88 Despite a substantial difference in the maximum force generated by

89 II, has also been completed, demonstrating a substantial difference in the strengths of the Fe-O link

90 that the position of substituents can make a substantial difference in the tendency to form helices.

91 ence interval, 81%-91%; P<.001), there was a substantial difference in the vaccine's effectiveness in

92 As we have shown previously, the substantial difference in time scales is what generates

93 ity and capacity are not associated with any substantial difference in U(VI) coordination.

94 We demonstrate substantial differences in 'adhesive signature' between

95 Substantial differences in acyl-coenzyme A profiles betw

96 No substantial differences in adverse effects were noted be

97 d RH differences that define the UHI lead to substantial differences in aerosol liquid water (ALW) co

98 TSPO ligands showed substantial differences in affinity between subjects cla

99 igher in the influenza-infected lungs due to substantial differences in Ag abundance in the two infec

100 Also, turbidity measurements confirm substantial differences in aggregation behavior dependin

101 region on 8q24 harboring three SNPs showing substantial differences in allelic frequency between cas

102 extent in MSTN(Delta/Delta) muscles, but no substantial differences in atrophy-related genes were ob

103 Substantial differences in average utilities were seen d

104 Both systems detected substantial differences in Bet v 1 content between aller

105 The substantial differences in binding affinity between DAG-

106 Despite these substantial differences in biophysical properties, both

107 pulations that colonize islands often evolve substantial differences in body size from their mainland

108 Substantial differences in bone marrow composition were

109 We also report substantial differences in BoPrP(Sc) levels in different

110 rity in Ca(2+) sensitivity, EF and CyaA have substantial differences in CaM binding and activation.

111 ta support a growing body of evidence noting substantial differences in cardiovascular risk by ethnic

112 We use a high-resolution analysis to show substantial differences in chromatin structure of pol II

113 There were substantial differences in consent rates among racial/et

114 present throughout the cortical mantle, with substantial differences in density and laminar distribut

115 Substantial differences in diagnostic practices that are

116 tly in vitro and in vivo, but they exhibited substantial differences in disease severity in mammals.

117 There are substantial differences in duration of mechanical ventil

118 pprove drugs for monotherapy) have not shown substantial differences in efficacy between drugs, FDA a

119 lence to established treatments did not find substantial differences in efficacy.

120 Despite substantial differences in energy intake, no systematic

121 ha1 domains from severe malaria isolates had substantial differences in EPCR binding affinity and blo

122 PE specification can lead to substantial differences in estimated rates of cognitive

123 These studies demonstrate substantial differences in exosomal miRNA profiles betwe

124 Pharmacokinetic alterations resulted in substantial differences in exposure between obese and no

125 These results quantify substantial differences in expression levels of the prot

126 erences in recognition, however, resulted in substantial differences in F105- and b13-bound conformat

127 There were substantial differences in frequency of universal/ARC MI

128 Charge depletion or accumulation resulted in substantial differences in friction force.

129 his finding supports the idea that there are substantial differences in frontal cortex structure and

130 Ensemble kinetic experiments revealed substantial differences in fusion of this plasma membran

131 n in the absence of the bulb correlated with substantial differences in gene expression as compared t

132 Substantial differences in gene expression were observed

133 ous population, individual cells can exhibit substantial differences in gene expression, protein leve

134 Overall, despite substantial differences in genotyping technologies, mark

135 Statistical testing for substantial differences in ghrelin blood levels over tim

136 There were substantial differences in indication for surgery betwee

137 ilar lability to photomineralization despite substantial differences in initial chemical composition.

138 Substantial differences in innate cytokine responses to

139 Substantial differences in intakes and in sources of n-3

140 nza epidemics are highly synchronous despite substantial differences in intensity, and inclusion of n

141 the VC1:IIC2 protein complex, but there are substantial differences in interactions of base, fluorop

142 of highly conserved genes, yet we discovered substantial differences in intergenic length and species

143 There are substantial differences in international guidelines for

144 hips for a single rate-determining step, and substantial differences in kinetic isotope effects for d

145 Despite substantial differences in kinetics of different antivir

146 ards a range of chromogenic substrates, with substantial differences in Km, kcat and degree of cooper

147 e of ATP are much too small to explain their substantial differences in light scattering.

148 ogeneity among influenza outbreaks including substantial differences in local outbreak timing and str

149 ay be responsible for regio-selectivity, and substantial differences in loop structures near the bind

150 Substantial differences in mean changes in drusen area,

151 The authors found substantial differences in mean fruit and vegetable cons

152 a suite of edaphic characteristics, driving substantial differences in microbial community compositi

153 We demonstrate substantial differences in morphological, molecular and

154 There were substantial differences in mortality rates and changes i

155 potassium were independently associated with substantial differences in mortality risk.

156 For snail kites, our method reveals substantial differences in movement strategies for diffe

157 GC-Th cells displayed substantial differences in mRNA for adhesion molecules,

158 These results reveal substantial differences in new neuron plasticity and fun

159 Such disparity helps to explain substantial differences in NK cell biology between human

160 However, there were substantial differences in observed vs. predicted mortal

161 aken from the classical MD simulation showed substantial differences in oxygen compression.

162 Substantial differences in pac1, an11, and ttg1 mutant p

163 Bioinformatics analysis reveals substantial differences in pathways involving Uba1- and

164 differences in taxation) are associated with substantial differences in per capita healthcare expendi

165 troporation (IRE), Bulvik et al demonstrated substantial differences in physiologic, tumorigenic, and

166 The model predicted substantial differences in population delay among all of

167 After adjustment, there were no substantial differences in prevalence/risk of diagnosed

168 ternary complexes are very small, there are substantial differences in protein dynamics.

169 Substantial differences in protein profiles, abundance,

170 ilk, despite their independent evolution and substantial differences in protein structure.

171 Substantial differences in reasons for and patterns of g

172 To this end, we demonstrated that there are substantial differences in receptor binding and infectiv

173 on mouse whole-genome BAC arrays, we uncover substantial differences in regional DNA content between

174 sporter, ZnT3) and channel blockers revealed substantial differences in relevant Zn(2+) sources, with

175 udies of the same phenotype/phenomena create substantial differences in results.

176 Despite substantial differences in rodent and human pancreatic p

177 Substantial differences in safety or immunogenicity betw

178 There were no substantial differences in sensitivity and specificity b

179 nes from two of the investigated clades, and substantial differences in sequence composition between

180 nd three-dimensional reconstruction indicate substantial differences in size and shape between ARC-L

181 erall results is unexpected, in that despite substantial differences in structures and charge distrib

182 atistical methods of data analysis can yield substantial differences in study power.

183 However, this naive analysis ignores substantial differences in study quality and design.

184 Additionally, substantial differences in SUVmax intraindividually were

185 Our results show that there are very substantial differences in synaptic vesicle recycling at

186 Bioinformatics analysis predicts substantial differences in targeting between miRNAs with

187 d T cells at equivalent levels despite their substantial differences in telomerase activity, and that

188 e methods reveal large-scale consistency but substantial differences in terms of small genomic rearra

189 Substantial differences in the 3-D architecture of the p

190 over several orders of magnitude, suggesting substantial differences in the accessibility or electros

191 Monocytes, B cells, and T cells showed substantial differences in the activation of p38 and the

192 es of entire predicted proteomes demonstrate substantial differences in the amino acid-sequence prope

193 There were systematic and substantial differences in the association between tempe

194 The eight variations resulted in substantial differences in the average number of correct

195 fibroblast cells were closely similar, with substantial differences in the B cells.

196 Although the enzymes share the same fold, substantial differences in the cavity of the catalytic s

197 We show that there are substantial differences in the composition of genotypes

198 There are substantial differences in the composition of globular d

199 Structural analysis revealed substantial differences in the contacts formed by the C-

200 The results indicate substantial differences in the covalent contributions to

201 These substantial differences in the cross-linking pattern are

202 ich crystal structures are available) reveal substantial differences in the degree of interaction of

203 of early-stage Parkinson's disease reported substantial differences in the development of these meta

204 Despite this structural similarity, substantial differences in the dimerization ability sugg

205 pecific) introns in eukaryotic genes reveals substantial differences in the distribution of informati

206 to-protein spin diffusion experiments reveal substantial differences in the dynamics and hydration of

207 processes occurring within muscle, there are substantial differences in the expression of IFNalpha/be

208 Clinical observations have documented substantial differences in the extent of collateralizati

209 Despite substantial differences in the extent of the damage to t

210 There were no substantial differences in the fatty acid composition of

211 There were substantial differences in the firing behavior among int

212 We found substantial differences in the functional potential of M

213 There were more substantial differences in the genome-wide profile of H3

214 and analytical ultracentrifugation revealed substantial differences in the hydrodynamic behavior of

215 ly reported for TAR bound to Mg2+, there are substantial differences in the hydrogen bond alignment o

216 There were substantial differences in the influence of the two capp

217 absence of structural information because of substantial differences in the interacting residues.

218 teriorly deformed in all three EG eyes, with substantial differences in the magnitude and extent of d

219 dose of infection or vaccination can lead to substantial differences in the magnitude and timing of A

220 rative untargeted metabolomics study to show substantial differences in the metabolic profiles of the

221 However, there were substantial differences in the micronutrient concentrati

222 Integrated molecular profiling showed substantial differences in the molecular features underl

223 Our analysis revealed substantial differences in the number and distribution o

224 conditions are defined, but also because of substantial differences in the number of FEs composing t

225 n these statistical findings, we showed that substantial differences in the number of grandchildren,

226 e recently duplicated Myb gene pairs display substantial differences in the numbers of synonymous sub

227 The observed data indicate substantial differences in the PEP subsites and open the

228 There are substantial differences in the phase and structure behav

229 ar to those Americans normally eat can cause substantial differences in the plasma tryptophan ratio a

230 uch as those Americans normally eat, produce substantial differences in the plasma tryptophan-LNAA ra

231 Our findings therefore reveal substantial differences in the primary sequences of prot

232 Substantial differences in the probability of conversion

233 sues, cerebellum and spinal cord, there were substantial differences in the profiles of mosaicism.

234 further suggest that there are likely to be substantial differences in the regulation of neuronal ex

235 ion, and glucose effectiveness, resulting in substantial differences in the regulation of postprandia

236 It also shows substantial differences in the relative abundance of vol

237 Comparison of the two structures reveals substantial differences in the relative positions of dom

238 We found substantial differences in the responses of effector and

239 The results reveal substantial differences in the role of prolyl and aspara

240 er this time scale are insufficient to cause substantial differences in the SID spectra of these comp

241 There were substantial differences in the socioeconomic/demographic

242 he lineage leading to mammals, together with substantial differences in the subcellular location of t

243 Substantial differences in the substrate specificities o

244 Despite substantial differences in the taxonomies (relative to 2

245 ell conserved across temperatures, there are substantial differences in the timescales over which the

246 lants vs. 126 systemic therapies) because of substantial differences in the trajectories of VRQoL.

247 expression profiling of MCF7 cells revealed substantial differences in the transcriptome following t

248 CheY homologs from the two species revealed substantial differences in the types of amino acid subst

249 There were no substantial differences in the utility scores between tr

250 that found in the native protein except for substantial differences in the vicinity of the proline r

251 Subclasses of immunoglobulin G (IgG) display substantial differences in their ability to mediate effe

252 tive sequences in potato and tomato revealed substantial differences in their abundance, 34.2% in pot

253 sequences and side chain chemistries lead to substantial differences in their observed interactions w

254 nd their derivatives in most cases; however, substantial differences in their odor threshold values w

255 ma1 and alpha/sigma2 hemicomplexes displayed substantial differences in their preference for particul

256 Inbred strains of mice exhibit substantial differences in their susceptibility to the r

257 )-fold decrease in k cat/ K m) and also show substantial differences in their thermodynamic parameter

258 ydration behavior for these proteins despite substantial differences in their three-dimensional struc

259 und delays throughout ACS care, resulting in substantial differences in total times for women and old

260 tails of the additive allele score exhibited substantial differences in trait levels (e.g., >1 mmol/L

261 , the ordering of events remains similar for substantial differences in trajectory resolution.

262 We find substantial differences in transcriptional frequency bet

263 in both the ribosomal A and P sites despite substantial differences in tRNA sequence, the type of es

264 In nucleosome core particles (NCPs), we find substantial differences in UDG-directed cleavage at urac

265 ospital and intensive care unit stays reveal substantial differences in unit efficiency.

266 of care than white stroke survivors without substantial differences in unmet need.

267 virus A/Turkey/England/647/77 as defined by substantial differences in viral shedding trajectories.

268 ed strain of P. aeruginosa, strain PAO1, has substantial differences in virulence from strain PA14 in

269 gregate dietary changes were associated with substantial differences in weight change (3.93 lb across

270 Our analysis reveals substantial differences in wiring and gross anatomy betw

271 from 1988-1994 through 2009-2010, there were substantial differences in women.

272 r mean improvements in visual function, with substantial differences observed as early as month 1, in

273 The substantial differences observed supports the need for b

274 es more methylated than wild-type ones; this substantial difference occurred throughout the genome, w

275 anscytolemmal water-exchange can result in a substantial difference of MECVF, compared with assuming

276 tforward use of the Hertz model results in a substantial difference of the Young's modulus between th

277 However, there are substantial differences of opinion regarding the effecti

278 These data suggest substantial differences of patient, physician, and famil

279 Substantial differences (P < 0.001) in transcript and ce

280 s of differentially regulated genes revealed substantial differences related to endoxifen concentrati

281 e cell extracts with this probe, we observed substantial differences, stressing the importance for bi

282 h their host mRNAs, we observe a subset with substantial differences that suggest regulated processin

283 Notwithstanding these substantial differences, the data show that correlation

284 h pre- and post-chemotherapy samples do show substantial differences, the timing of the divergence is

285 A substantial difference up to 20% between coefficients in

286 No substantial difference was found between results obtaine

287 No substantial difference was noted in overall survival, an

288 In contrast, no substantial difference was observed in the acyl chain co

289 Substantial differences were found between clinical diag

290 No substantial differences were found between the scores of

291 No substantial differences were found in absolute lymphocyt

292 Substantial differences were found in RIs for every vess

293 milarly complex binding characteristics, and substantial differences were noted between the PRDs from

294 domain of TLR10 with low sequence homology, substantial differences were observed at helices alphaC,

295 No substantial differences were observed between groups in

296 Substantial differences were observed in the ability of

297 No substantial differences were observed in the distributio

298 starvation for different nutrients and found substantial differences: When deprived of leucine or ura

299 The results show substantial differences with respect to the mature fibri

300 Worldwide there are substantial differences within and between countries in