ライフサイエンスコーパス: substrate level

1 tracking is integral to the structure at the substrate level.

2 ense oligonucleotides in the presence of low substrate level.

3 reased enzyme activity and not to changes in substrate level.

4 ells were correlated with >50% reductions in substrate levels.

5 nd contribution to the control of conjugated-substrate levels.

6 ovide a complete model for the enzyme at all substrate levels.

7 This substrate-level activation does not require autophosphor

8 doxin, which increases the efficiency of the substrate level and electron transport phosphorylations.

9 reference, adapting to the prevailing plasma substrate levels and hormonal milieu, but in type 1 diab

10 rs to run with a constant speed at different substrate levels and, therefore, is a substantial criter

11 A (alpha-GalA) activities, glycosphingolipid substrate levels, and in vitro mutation expression were

12 tate production and a significant portion of substrate-level ATP produced anaerobically, were tested

13 romote anaerobic metabolism and thus sustain substrate-level ATP production.

14 ions and/or contributions from oxidative and substrate-level bioenergetics is unknown.

15 t mammalian antioxidant, is regulated at the substrate level by cysteine, which is synthesized from h

16 Adenine nucleotides at substrate level concentrations inhibit the reaction of L

17 unded plants, but that the AOS hydroperoxide substrate levels, controlled by upstream enzymes (lipoxy

18 rometry-based enzyme functional analysis and substrate level-controlled enzyme kinetics consistently

19 tegy that allows acetic acid removal without substrate-level (de)phosphorylation may instead be emplo

20 the effects of metabolite concentrations and substrate-level enzyme regulation while identifying meta

21 rial oxidative phosphorylation, increases in substrate level generation of ATP and reducing equivalen

22 Plasma hormone and substrate levels, hepatic gluconeogenic gene expression,

23 relates with lowered pERK but unchanged pPKA substrate levels in D1 medium spiny neurons as well as i

24 ormation of synthetic prions and the role of substrate levels in their evolution.

25 associated negative PE occurred even at low substrate levels in this study could be attributed to li

26 Interestingly, high substrate levels in vitro significantly reduce Cdc20 aut

27 tive interventions aiming at alleviating the substrate-level inhibition of key enzymes in order to en

28 idic operations, instrument portability, and substrate-level integration with other pre- and post-PCR

29 proteasome inhibition, and this increase in substrate level is consistent with the observed loss of

30 zation of genome-annotated, respiratory, and substrate-level lactate dehydrogenases (LDHs) from the o

31 erability of DA neurons and that enhancing G-substrate levels may be a neuroprotective strategy for t

32 e the complete inhibition of MOC, indicating substrate level phosphorylation and explicit anaerobic s

33 ondrial enzyme capable of ATP production via substrate level phosphorylation in the absence of oxygen

34 ion of acetate to methane that yields ATP by substrate level phosphorylation.

35 ee acids results in the formation of ATP via substrate level phosphorylation.

36 robically generate ATP by intramitochondrial substrate-level phosphorylation and maintain DeltaPsi(m)

37 ATP is generated exclusively by substrate-level phosphorylation in hydrogenosomes, as op

38 ctions and is not fermentative, we find that substrate-level phosphorylation is its primary anaerobic

39 In bloodstream-form organisms, substrate-level phosphorylation of glucose is sufficient

40 ed cells with Embden-Meyerhof glycolysis and substrate-level phosphorylation that lack the alpha-prot

41 oduce an acyl-CoA that is ultimately used in substrate-level phosphorylation to produce ATP.

42 tron acceptors, generates ATP primarily from substrate-level phosphorylation under anaerobic conditio

43 Since substrate-level phosphorylation via the Embden-Meyerhof

44 ive phosphorylation via the pmf, but also by substrate-level phosphorylation via the enzyme AckA.

45 te as the electron acceptor, consistent with substrate-level phosphorylation yielding a significant a

46 asses (e.g., fermentation pathways bypassing substrate-level phosphorylation), substrate channeling (

47 ding carbon fixation, the shikimate pathway, substrate-level phosphorylation, gluconeogenesis and gly

48 hydrogenosomal-type pyruvate metabolism and substrate-level phosphorylation.

49 c acid cycle enzyme that conserves energy by substrate-level phosphorylation.

50 e ATP needed for cell growth is derived from substrate-level phosphorylation.

51 ounted for if ATP synthesis occurred only by substrate-level phosphorylation.

52 n of hexokinase II and production of ATP via substrate-level phosphorylation.

53 We investigated how mutant SPT and substrate levels regulate neurite growth.

54 is significantly higher than of disulfides, substrate level regulation favors the synthesis of H2S o

55 This suggests that OAP may be a form of substrate level regulation in PG biosynthesis.

56 ranscriptional and translational regulation, substrate-level regulation of enzyme activity, post-tran

57 457 model reactions, 337 metabolites and 295 substrate-level regulatory interactions.

58 conditions of reduced mitogen or nutritional substrate levels, the serine/threonine kinase target of

59 PKA activity is regulated at the substrate level through interactions of PKA regulatory s

60 suggest that the early kinetic events at the substrate level ultimately govern successful chaperonin-

61 ne was adaptively regulated by extracellular substrate level via transcriptionally mediated mechanism

62 These structures provide the first substrate-level view of the local structural differences

63 enzyme); conversely, when the intracellular substrate level was reduced by methionine deprivation, t

64 IFG effects on GCase stability and substrate levels were evaluated in a mouse model (hG/4L/