ライフサイエンスコーパス: subtoxic

1 human liver to demonstrate that ethanol, at subtoxic and physiologically relevant concentrations, en

2 pha (1 ng/mL) in the presence and absence of subtoxic and TC50 doses of chemicals for 24 hrs at 37 de

3 is activated in the retina after exposure to subtoxic bright light, mechanical trauma, and systemic a

4 Coexposure of K562 or LAMA84 cells to subtoxic concentration of flavopiridol (150-200 nM) and

5 posure of granule cells for 2 and 5 min to a subtoxic concentration of NMDA (100 microM) evoked an ac

6 ease in the lung epithelial cells already at subtoxic concentrations (1-10 mug/mL) but not in immune

7 brane phospholipids, we found that phenol at subtoxic concentrations (50 microM) caused oxidation of

8 00 microM phenol, we conclude that phenol at subtoxic concentrations causes significant oxidative str

9 ure of cells to activated prodrug or drug at subtoxic concentrations enhanced viral DNA replication.

10 s of the metastatic process were affected by subtoxic concentrations of 6BIO, which inhibited adhesio

11 e also demonstrate that activation of JNK by subtoxic concentrations of anisomycin induced selective

12 ither arsAB or arsA(C113A/C422A)B growing in subtoxic concentrations of arsenite, cells bearing wild

13 Subtoxic concentrations of camptothecin (which stabilize

14 Here, we show that transient exposure to subtoxic concentrations of commonly used anticancer drug

15 an umbilical vascular endothelial cells with subtoxic concentrations of docetaxel (20 pmol/L) in vitr

16 heir ability to inhibit DNA repair in vitro, subtoxic concentrations of L67 and L189 significantly in

17 We found that subtoxic concentrations of LOOH increased CaCo-2 cell ap

18 In this study, we found that subtoxic concentrations of PS-341 potently sensitized MM

19 Subtoxic concentrations of Tat and gp120, when incubated

20 Combined exposure of U937 cells to subtoxic concentrations of UCN-01 and L744832 resulted i

21 Subtoxic concentrations of vanillin did not affect the A

22 SIV-tk replication were sensitive to GCV at subtoxic concentrations, and virus-infected cells were e

23 At subtoxic concentrations, BAs dramatically stabilized dom

24 in-dependent endosome-scission inhibitor, at subtoxic concentrations, suggesting that the early captu

25 de), and CdSe/ZnS core/shell quantum dots at subtoxic concentrations.

26 ntiation of cytotoxicity was observed when a subtoxic dose of CB-184 was combined with doxorubicin or

27 bone marrow suppression elicited SOS from a subtoxic dose of Mct, whereas infusion of bone marrow du

28 LT and LTB had adjuvant activity at subtoxic doses and induced more consistent antibody resp

29 s HIV-1 and SIV infection of target cells at subtoxic doses in vitro.

30 r, toxicity and relative lack of efficacy at subtoxic doses limit the use of gentamicin for suppressi

31 strated that treatment with a combination of subtoxic doses of 2-DG and the IGF1R inhibitor II reduce

32 Finally, neonatal rats were given apparently subtoxic doses of chlorpyrifos either on postnatal days

33 of ATP hydrolysis by ABCG2 transporters with subtoxic doses of curcumin combined with stimulation of

34 of ATP hydrolysis by Na(+),K(+)-ATPase with subtoxic doses of gramicidin A or ouabain.

35 After exposure to subtoxic doses of heavy metals such as mercury, H-2(s) m

36 After exposure to subtoxic doses of heavy metals such as mercury, H-2(s) m

37 After exposure to subtoxic doses of heavy metals such as mercury, H-2s mic

38 In certain strains of mice, subtoxic doses of HgCl2 (mercuric chloride; mercury) ind

39 In genetically susceptible H-2s mice, subtoxic doses of mercuric chloride (HgCl2) induce a com

40 etal-induced autoimmunity, administration of subtoxic doses of mercury (a common environmental pollut

41 Addition of subtoxic doses of perifosine to cetuximab treatment also

42 The concurrent application of subtoxic doses of soluble oligomeric forms of human amyl

43 rons were exposed to AMPH in the presence of subtoxic doses of the mitochondrial complex I inhibitor

44 esults showed that 2-MeO-E(2) at nontoxic or subtoxic doses selectively enhanced the effects of certa

45 e of cells in culture to AgNPs or Ag ions at subtoxic doses would alter the effective metabolism of s

46 ssuade insects and other predators) that, at subtoxic doses, activate adaptive cellular stress-respon

47 In subtoxic doses, addition of PLA2 significantly reduced h

48 Here, we report that subtoxic drug concentrations are sufficient to inhibit p

49 uoride cytotoxicity and to determine whether subtoxic F exposure affects tubular cell vulnerability t

50 To determine whether subtoxic F exposure alters tubular cell susceptibility t

51 PLA2 depletion subsequently results, and 4) subtoxic fluoride exposure can acutely increase cell res

52 normal excitatory signaling and maintaining subtoxic glutamate concentrations in mammalian central n

53 timicrobial peptide (CAMP), in response to a subtoxic level of endoplasmic reticulum (ER) stress that

54 reduce intracellular drug concentrations to subtoxic levels by mediating drug efflux across the cell

55 The tumor cells that are exposed to subtoxic levels of DNA synthesis-targeting drugs will be

56 In response to subtoxic levels of ER stress, increased sphingosine-1-ph

57 ergic signal transduction was disrupted with subtoxic levels of exposure to AP.

58 h levels of glutamate induce retinal damage, subtoxic levels of glutamate directly stimulate Muller g

59 Collectively, the study shows that subtoxic levels of LOOH disrupt intestinal redox homeost

60 t suppress or promote MLP suggests roles for subtoxic levels of MLP in neuronal plasticity.

61 in H2O2 and cell death following exposure to subtoxic levels of paraquat.

62 In this study, subtoxic levels of raltegravir were shown to inhibit the

63 Treatment early in infection with subtoxic levels of wild-type peptide reduced viral infec

64 cing the intracellular drug concentration to subtoxic levels.

65 We also confirmed that subchronic subtoxic MA experience elicits a hyperglutamatergic stat

66 o superimposed injury, cells were exposed to subtoxic NaF doses for 0 to 24 hours and then challenged

67 When subtoxic NaF doses were applied, partial cytosolic PLA2

68 also suggest the therapeutic application of subtoxic NPI-0052 concentrations in combination with TRA

69 Coadministration of subtoxic or marginally toxic concentrations of 2-ME and

70 Cotreatment of K562 or LAMA cells with subtoxic or marginally toxic concentrations of PD184352

71 Coadministration of subtoxic or minimally toxic concentrations of CFZ) with

72 WCNT) doses at or below 1 mg/L, which proved subtoxic since there were no adverse effects on the grow