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1 y-2-oxo-heptane-1,7-dioate into pyruvate and succinic semialdehyde.
2 toglutarate decarboxylase (Kgd) and produces succinic semialdehyde.
3 t of alpha-ketoglutarate decarboxylation was succinic semialdehyde.
4 catalysing gamma-aminobutyrate conversion to succinic semialdehyde.
5 s, we determined that glutamate, rather than succinic semialdehyde, accounts for the metabolic phenot
6 the degradation of vitamin B(6) and produces succinic semialdehyde, acetate, ammonia, and carbon diox
7 of 2-(acetamidomethylene)succinate to yield succinic semialdehyde, acetic acid, carbon dioxide, and
9 s also associated with reduced expression of succinic semialdehyde dehydrogenase (encoded by ALDH5A1)
10 nobutyrate transaminase (GabT and PuuE), and succinic semialdehyde dehydrogenase (GabD and PuuC).
18 ing a novel 2-oxoglutarate decarboxylase and succinic semialdehyde dehydrogenase were identified in t
19 pathway or alpha-ketoglutarate decarboxylase/succinic semialdehyde dehydrogenase) plays a minimal rol
23 lic intermediates, gamma-hydroxybutyrate and succinic semialdehyde, inactivated the AttJ repressor in
24 the GABA degradation pathway, the substrate, succinic semialdehyde, is shunted towards production of
26 he cellular expression of AKR family member, succinic semialdehyde reductase (AKR7A2) that reduces to
29 mutations of ALDH1, ALDH2, ALDH4, ALDH10 and succinic semialdehyde (SSDH) genes have been emerged.
30 satisfied with pyridoxamine 5'-phosphate and succinic semialdehyde, the products of a GABA-dependent
31 succinic semialdehyde dehydrogenase converts succinic semialdehyde to succinate, an intact gamma-amin
32 oduces two catabolic products, glutamate and succinic semialdehyde, we sought to determine which was
33 a PLP-dependent enzyme that degrades GABA to succinic semialdehyde, while reduction of GABA concentra
34 ransmitter gamma-aminobutyric acid (GABA) to succinic semialdehyde with concomitant conversion of pyr
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