ライフサイエンスコーパス: such

1 For such a complex reaction with membranes, it has been diff

2 Here, we report that T cells activated in such a context are mainly IFN-gamma(+), adhere to CFB, a

3 r, is particularly challenging to measure in such a format due to complexities involved in sample pre

4 We show that such a framework is consistent with the stationary-state

5 To investigate whether such a mechanism could be an endogenous trigger for auto

6 In this work we demonstrate that such a photosensitiser, chlorin e6, can be repurposed fo

7 Such a segregation of function would predict that when a

8 Such a strategy may offer an important new approach to t

9 rough further gene deletion could compromise such a strategy.

10 The high cognitive load required to navigate such a workflow is detrimental to hypothesis generation.

11 Such activation of neutrophils under conditions mimickin

12 However, risks associated with such activities have been identified, specifically the t

13 Such adhesive interactions enhanced levels of active Rac

14 atient outcomes in several human cancers, no such advance has been achieved in muscle-invasive bladde

15 ns in the transcriptome of NAc MSNs, but how such alterations influence cocaine's effects on dendriti

16 present the structure of the Fab fragment of such an antibody.

17 Such an approach may find use in label-free selection of

18 the fate of HSPCs is important for exploring such applications.

19 In one such approach, an understanding of the distal and geomet

20 Such approaches promise to improve drug specificity by r

21 nd human proteome microarrays, and we expect such approaches to contribute substantially to the under

22 s with a relatively long physical half-life, such as (89)Zr.

23 Compounds such as 20 were prepared using a palladium-catalyzed Ull

24 uilt upon more successful existing programs, such as a Medicare for All.

25 s of the IFN-inducible PYHIN protein family, such as absent in melanoma-2 and IFN-gamma-inducible pro

26 racterized by dysfunctional decision-making, such as addiction and pathological gambling.

27 ation of downstream targets of AXL signaling such as AKT and P70S6K.

28 tate access of IRS-2 to downstream effectors such as AKT.

29 was helpful to annotate specific compounds, such as alkaloids, saponins, flavonoids, and terpenoids,

30 the genetic architecture of complex traits, such as allele frequency and effect size.

31 st the development of inflammatory diseases, such as allergy, asthma, and inflammatory bowel disease.

32 Neuroactive steroids such as allopregnanolone may be potential therapeutic ta

33 uppressed the growth of all competing fungi, such as Alternaria, Epicoccum and Ulocladium species.

34 ne related to immune-to-brain communication, such as Alzheimer's and Parkinson's diseases.

35 on, whereas a less radical stabilizing group such as an alkyl or amide group at the C3-position of in

36 s for the medical proposes due to properties such as an elevated surface area and excellent electrica

37 A radical stabilizing group such as an ester or ketone moiety at the C3-position of

38 the androgen receptor (AR) and AR variants, such as AR-V7, at their conserved SET/NAP domain, and ex

39 Consumption of amino acids such as arginine and tryptophan by immunoregulatory macr

40 isingly, mRNA levels of key ISR gene targets such as Atf5 and Trib3 failed to increase.

41 cal event in chronic inflammatory processes, such as atherosclerosis, but the control of the vascular

42 for DFT calculations of material properties such as atomic spin and orbital magnetic moments and loc

43 onal aspects of several biological processes such as autophagy, inflammation, proliferation and diffe

44 scovery of materials with target properties, such as auxetics, using high-throughput computations, op

45 tion and the expression of downstream genes, such as Bcl-2 (B-cell lymphoma 2), c-Myc, MMP7 (matrix m

46 t translate to sex-specific adverse outcomes such as behavioral deficits is a possibility that merits

47 not easily obtainable with other techniques, such as behavioral responses to pharmacological manipula

48 be responsive to various environmental cues, such as bile salts and alkaline pH, but how these factor

49 twork motifs that lead to functional outputs such as bistability or oscillations.

50 nents have demonstrated a range of functions such as bistability, oscillation, feedback, and logic ca

51 Higher-order states, such as bound biexcitons, are possible but are difficult

52 drug design, important for managing diseases such as cancer and Alzheimer's disease.

53 nators with relatively high quality factors, such as cantilevers vibrating in vacuum, can show charac

54 Somatic mutations such as CARD11 may have an impact on response to ibrutin

55 New drugs with novel mechanisms of action, such as cardiac myosin activators, are under investigati

56 several nutrients in fruits and vegetables, such as carotenoids.

57 osomal or multi vesicular body (MVB) markers such as CD81 and VPS4 and decreased co-localization with

58 cation of IL-4-upregulated surface proteins, such as CD90, CD108, CD109, and CD200R (CD200R1).

59 tures unique to various modes of cell death, such as cells undergoing apoptosis versus necrosis/necro

60 strong inhibitions of molt-related proteins such as chitinase and JHE-carboxylesterase.

61 rders related to primary cilia dysfunctions, such as ciliopathies and certain types of cancer.

62 Following widely accepted guidance, such as Cochrane or Institute of Medicine standards for

63 qH operates under stress conditions such as cold and high light and is photoprotective, as i

64 Venom peptide toxins such as conotoxins play a critical role in the character

65 atures of cross-modal stimulus constituents, such as contrast, frequency, congruency, and temporal st

66 -dipole interactions, which govern phenomena such as cooperative Lamb shifts, superradiant decay rate

67 sociated with chronic inflammatory diseases, such as COPD, in patients with hemoptysis, TAE of the BA

68 st alternative hydraulic architectural rules such as da Vinci's rule or Murray's rule, or physiologic

69 ablished arthropod-borne infectious diseases such as dengue and yellow fever and emerging diseases su

70 ssues, thanks to many philosophical currents such as deontological ethics and consequentialism.

71 with lifestyle changes in Western societies, such as dietary modifications and increased antibiotic u

72 ompetition experiments using polar solvents, such as DMF, no "mixed" products possessing structurally

73 viral therapy; HIV-associated comorbidities, such as dyslipidemia, drug abuse, and opportunistic infe

74 tep mechanism for HCCS, whereby HCCS mutants such as E159A are enhanced in release (step 4) of cyt c

75 Many techniques such as electroporation, lipofection or microinjection h

76 (5'-diphosphates) in some signaling events, such as extracellular signal-regulated kinase 1/2 and la

77 havior in response to environmental changes, such as fluctuations in food abundance, to maximize surv

78 influenced by perception of bitter compounds such as glucosinolates (GSLs) and isothiocyanates (ITCs)

79 Atomically thin materials such as graphene are uniquely responsive to charge trans

80 poor understanding of how mutations in genes such as GRN contribute to disease pathogenesis and neuro

81 suppressed agonist Emax) in signaling events such as guanosine 5'-3-O-(thio)triphosphate binding and

82 electrode during MES rely on: (i) mediators such as H2; (ii) physical contact through electron-trans

83 e sequenced samples, rather than public data such as HapMap or dbSNP, to train an accurate classifier

84 odulation of ligand-gated chloride channels, such as hetero-oligomeric alpha1beta2gamma2 GABAA recept

85 d SUVs were compared with prognostic factors such as histologic grade (G1, G2, or G3, for low-grade [

86 7 target genes in multiple cancer cell lines such as HMGA2 and MYC.

87 distribution of the well-known Lewis pairs, such as how they are distributed in space and how their

88 rmal reproduction, particularly in a species such as humans with low population differentiation.

89 espond instead to locally produced cytokines such as IL-33.

90 d dynamic cell behavior, including processes such as induced pluripotency and differentiation.

91 previously unknown signatures of infection, such as induction of potassium channels and amino acid t

92 may support sensory aspects of the decision, such as interpreting the visual signals so that evidence

93 DNA tumor viruses such as Kaposi's sarcoma-associated herpesvirus (KSHV) a

94 eriments using targeted genome manipulations such as knockouts or transgenics.

95 ntaining minor inorganic seawater components such as magnesium and calcium.

96 consistent with primary magmatic processes, such as mantle heterogeneity or change in depth of melt

97 g high-throughput reporter assay experiments such as massively parallel reporter assays (MPRAs) and s

98 psulate and release bulky globular proteins, such as mCherry, in a light-dependent manner.

99 s, and are therefore needed for applications such as medical implants, tissue engineering, soft robot

100 om the geometrical cell-membrane properties, such as membrane curvature, volume, and surface area.

101 Genetic and environmental factors, such as metals, interact to determine neurological trait

102 Major dicarbonyl compounds such as methylglyoxal or glyoxal are found to be the mai

103 the reversible insertion of multivalent ions such as Mg(2+) and Al(3+) into electrode materials remai

104 ng molecules to regulate stem cell behaviors such as migration.

105 urodegenerative conditions affecting humans, such as multiple sclerosis, neuromyelitis optica spectru

106 le or Murray's rule, or physiological models such as Munch's Pressure Flow hypothesis.

107 uman SF3b1 have been linked to many diseases such as myelodysplasia (MDS) and cancer.

108 The existing KCa activators, such as naphtho[1,2-d]thiazol-2-ylamine (SKA-31), 6,7-di

109 oduce negative long-term health consequences such as neurodegenerative disease.

110 involved also in more specialized processes such as neurogenesis and growth factor signaling.

111 o prove useful for imaging other structures, such as neurons in the brain.

112 nA is selectively depleted in myeloid cells, such as neutrophils, we show that FlnA negatively regula

113 therapeutic targeting of a signaling pathway such as NG2/CSPG4 may have different effects on cell beh

114 ut the significant release of intermediates, such as nitrous oxide.

115 ing flowering and grain filling using donors such as NL-44, will minimize the negative impact of heat

116 nt of cells with pharmacological inhibitors, such as nonsteroidal anti-inflammatory drugs or small in

117 r results suggest that Fe-rich clay minerals such as nontronite can form rapidly under oxidized condi

118 s of overdispersed (evenly spaced) elements, such as North American Mima mounds, Brazilian murundus,

119 be an important feature of chronic disorders such as obesity and type 2 diabetes.

120 Atypical antipsychotics such as olanzapine often induce excessive weight gain an

121 As for other disciplines, such as oncology or rheumatology, we have to approach AD

122 oney is also affected by many other factors, such as overfeeding of bees with sucrose, harvesting pri

123 d that IgE activation aligned with processes such as oxidative phosphorylation, angiogenesis, and the

124 MS is a unique feature of respiratory yeasts such as P. pastoris and C. albicans, and it may have nov

125 re implicated in neurodegenerative disorders such as Parkinson's disease (PD), it is important to exa

126 oach for the treatment of synucleinopathies, such as Parkinson's disease, dementia with Lewy bodies,

127 nctional neurosurgery for movement disorders such as Parkinson's disease, tremor, and dystonia involv

128 d to increase in neurodegenerative disorders such as Parkinson's disease.

129 lls are a rich source of bioactive molecules such as peptides, hormones, and neurotransmitters, but r

130 ul weapons in the fight against foreign DNA, such as phages and plasmids, as well as a revolutionary

131 eraction between the electromagnetic fields, such as phase noises and spontaneous Raman scattering.

132 hat can associate with anionic phospholipids such as phosphatidylserine.

133 iring chronic increase in energy production, such as physiologic or pathologic cardiac growth, remain

134 elated to a specific diagnosis), infections, such as polyomavirus-associated nephropathy, calcineurin

135 l disadvantages that can reduce sensitivity, such as probing only a small percentage of the nanoprobe

136 Signaling proteins such as protein kinases adopt a diverse array of conform

137 urification is applied by other disciplines, such as proteomics.

138 might involve modulatory regulatory factors such as R-spondin 1 (Rspo1), an extracellular protein th

139 detection is mainly based on large equipment such as readers and imaging systems, which require inten

140 Adaptor proteins such as receptor-interacting serine/threonine-protein ki

141 er disease) or is a significant risk factor, such as reflux esophagitis and gallstones.

142 d ventral tegmental area regulate behaviours such as reward-related learning, and motor control.

143 it underlies all secondary genomic analyses such as RNA sequencing (RNA-Seq), chromatin immunoprecip

144 tools with other types of experimental data such as RNA-seq or ChIP-seq.

145 ques that rely on reverse transcription (RT) such as RT-qPCR and RNA-Seq.

146 uld not be present in Kosher and Halal foods such as saffron.

147 articularly applicable to migratory species, such as salmon, where distinct temporal changes in growt

148 e tool to guide the self-assembly of defects such as scars, pleats, folds, blisters, and liquid cryst

149 rtant when affecting habitat-forming species such as seagrasses, as the consequences on their abundan

150 Current treatments, such as selective serotonin reuptake inhibitors, are not

151 ing behavior in the dynamical phase diagram, such as self-trapped localized motion, 2-D diffusive exp

152 gained considerable interest in applications such as sensors, detectors, energy harvesting cells, and

153 more feasible than other possible mechanisms such as single electron transfer, halogen atom transfer,

154 hene (FLG) systems on a dielectric substrate such as SiO2, the addition of each extra layer of graphe

155 he hypothesis that realistic land conditions such as soil moisture/soil temperature (SM/ST) can signi

156 In conclusion, cultivation practices such as sowing date and successive harvesting may be use

157 was applied to analyse plant-based beverages such as soy, oat and rice.

158 work identifies simple synthetic parameters, such as stirring rate, that may be exploited to design o

159 nt with medications and confounding factors, such as substance use, previous adverse birth outcomes,

160 concentrations of recalcitrant contaminants such as sucralose, sulfamethoxazole and carbamazepine, w

161 e magnetic resonance (MR) imaging modalities such as T1-weighted and diffusion-weighted MR imaging co

162 olled by a combination of multiple forcings, such as tectonics, sea-level fall and long-term decline

163 in new ways as well as to exogenous stimuli, such as temperature, magnetic field, and optical light.

164 le to abstract H-atoms from weaker X-H bonds such as TEMPO-H to re-form 2.

165 titumor activities of immunomodulatory drugs such as thalidomide, lenalidomide, and pomalidomide, rec

166 novel insights on transcriptional regulation such as the "hit-and-run" model and transcription bursti

167 comprise vast, highly differentiated domains such as the axon and dendrites.

168 ion, we address new areas of lncRNA biology, such as the functions of enhancer RNAs, circular RNAs an

169 d lower complexity relative to other niches, such as the gut.

170 tion of effective process control procedures such as the Hazard Analysis Critical Control Point syste

171 ur-suppressing roles for cancer progression, such as the insulin-like growth factors.

172 Single-cell features such as the irregularity of spiking and the frequency de

173 ls, actin dynamics are regulated by kinases, such as the LIM domain kinase (LIMK), which regulates ac

174 rtant tissues that may be sites of infection such as the lungs and soft tissues.

175 matched only by other extinct molluscivores such as the marine bear Kolponomos.

176 , downward-skewed probability distributions, such as the skewed Student [Formula: see text] used here

177 Dramatic events in human prehistory, such as the spread of agriculture to Europe from Anatoli

178 biomolecules include amyloidogenic peptides, such as the well-known amyloid-beta peptide involved in

179 e), thus in effect linking diverse exposures such as those from dietary intake and the microbiota wit

180 ently plastic to integrate multiple signals, such as those from microbes, damaged tissues, and the no

181 in heterodimeric reaction-center structures, such as those reported previously.

182 riants associated with smaller effect sizes, such as those that underlie complex diseases.

183 Alternative schemes, such as those that use high-dimensional quantum codes in

184 enting colorectal cancer in high-risk groups such as those with familial adenomatosis polyposis (FAP)

185 ition, nonsemiconductor type photocatalysts, such as Ti-Si molecular sieves and carbon quantum dots (

186 We propose that chaperones such as trigger factor can work as foldases under force,

187 label-free detection of explosive molecules such as trinitrotoluene (TNT) down to 10(-10)M in concen

188 es, including mast cell-restricted proteases such as tryptase.

189 -M78, and J-M267) and mitochondrial lineages such as U6b, in addition to common Eurasian haplogroups

190 between MACL and markers of oxidative stress such as urinary methionine sulfoxide were observed in Hh

191 have important implications for biotherapies such as vaccines and monoclonal antibodies.

192 For common diseases such as VTE, biobanks provide potential to perform genet

193 gh for observing subtle near-surface changes such as water content variations and permafrost alterati

194 an point to larger networks of interactions, such as with proteins that serve as hubs for essential c

195 engue and yellow fever and emerging diseases such as Zika and chikungunya, all of which are transmitt

196 hermore, CIPHER conducts downstream analysis such as: narrow and broad peak calling, peak annotation,

197 Such autoimmunity has been shown to be highly toxic in s

198 the service of the explicit justification of such beliefs.

199 Such biomolecules include amyloidogenic peptides, such a

200 ries, in addition to sensory information, in such categorical cue combination tasks.

201 ghts the possibility that the bioactivity of such CECs may be effectively preserved through direct co

202 Such cements remain in the tooth and fail to degrade and

203 when experience-dependent plasticity shapes such circuits.

204 rammes working in similar circumstances with such complex interventions.

205 Such conditions arise in multicellular communities, wher

206 Here we illustrate how such conditions promote chemotherapy resistance in pancr

207 Under such conditions, fructose lowers whole-body glycogen syn

208 o help give us a possible scenario worthy of such conjecture.

209 ing mechanism, and the biological meaning of such connectivity remains obscure.

210 As a result, such conserved functional modules can be identified thro

211 dium dioxide (VO2) is a canonical example of such correlations.

212 One such cue is floral temperature, created by captured sunl

213 ch control drug response and illustrates how such data can add substantial confidence to target ident

214 attention to the inherent spatial aspects of such data.

215 Such differences may have clinical significance, as ther

216 Such differences may ultimately contribute to their uniq

217 vidence of antiepileptic efficacy or lacking such evidence, we demonstrated that our set of repurposa

218 Such expressional divergences suggest that FACs are util

219 Such form of cross-over of stress may be beneficial if i

220 As such, functional and anatomical measures provide indepen

221 One such gene is Wilms' tumour 1 (WT1), which plays multiple

222 A common analysis step is to annotate such genomic regions to genomic annotations (promoters,

223 dered to be the primary mechanism underlying such impedance based microflow sensors.

224 We investigated whether such impressions also influence the communication of sci

225 response and immunity, and we highlight how such improvements enable a greater understanding of the

226 Such independent genetic control suggests that breeders

227 As such, Indonesia is home to nearly 20% of the world's "mi

228 olling polycation-membrane interactions, yet such information is surprisingly difficult to obtain at

229 The North American Great Plains exemplify such intraplate earthquake localization, with both natur

230 Such invariability-especially when juxtaposed with the d

231 Such is the case for NE Atlantic marine macroalgal fores

232 To overcome such limitations, protein transduction domains (PTDs) ha

233 is not feasible in clinical practice, and as such limits the generalizability of findings.

234 Such loose linkage between the alphaI and betaI is attri

235 ssed inter- and intraobserver variability of such measurements, and explored the mechanism of any pla

236 t studies have highlighted the importance of such metabolic regulation in the endothelium and uncover

237 Such Mn(II)-phyllomanganate reactions may thus alter met

238 y been conducted and the expressive power of such models for real human subjects remains unknown.

239 y-step tutorials that demonstrate how to fit such models in a variety of software programs.

240 Existing probabilistic inference methods for such models rely on subjective filtering and suffer from

241 ng the formation, storage, and expression of such models remain unknown.

242 nd investigating the diagnostic relevance of such molecules in childhood.

243 uld allow molecular-level phenomena to drive such movements in artificial systems remains a scientifi

244 Although such mutant proteins are prone to aggregation, toxicity

245 Such nanoparticles are investigated in terms of their cy

246 ing gecko Gymnodactylus amarali between five such newly created islands and five nearby mainland site

247 One such nuclear receptor is DAF-12, which is required for n

248 As such, our finding contradicted observations from cell cu

249 in determining the electrical conductance of such parents and daughters.

250 cles, and the latter can be used to assemble such particles into bulk materials.

251 Identification of such patients offers the possibility of commencing or es

252 y contrast, heterochiral sequences that lack such persistence selectively attack bacterial membranes

253 nd elevated reactive oxygen species, whereas such phenotypes were reversed by its product lactate or

254 te-determining step in the stereomutation of such piperidines is the piperidine ring flip and not nit

255 nish limited antibiotic use and suggest that such practices could help reduce the load of antibiotic-

256 ynchronized, and full withdrawal of OPV, and such preparation would be aided by setting a reasonably

257 here that the synergistic application of two such principles in the design of peptoid foldamers yield

258 ncers have been systematically identified in such projects as FANTOM and ENCODE, forming genome-wide

259 To investigate such protein interactions, we establish a ribosome affin

260 hiff bases have been reported to result from such reactions.

261 ia transmission model we demonstrate that in such regions dominated by zoophilic vectors, existing ve

262 ession in cancer, it remains unknown whether such regulatory loops operate also in non-transformed ce

263 turity to provide substantial evidence about such representations.

264 a gonorrhoeae senses and responds to stress; such responses may be modulated by MisRS (NGO0177 and NG

265 The analysis of data at such scales has brought statistical and machine learning

266 However, such scales may be affected by intrarater and inter-rate

267 Such self-assemblies describe not only the basic structu

268 Moreover, such sensitivity enables differentiation between cell ty

269 STs in ILTCFs suggests that the ecosystem in such settings might be more conducive for intrafacility

270 generally considered to remain resistant to such shrub expansion in the next decades.

271 For fluorene, such signature is not identified probably due to lower o

272 The factors explaining such similarities are still debated, and the role played

273 Specific ion binding to such sites induces changes in the filter conformation, w

274 slippage-prone template motif sequence 3' of such 'slippage-stimulatory' structures.

275 Experimental discovery of such solitons is hindered by the need for spatial imagin

276 Such states are often invoked in the excited-state dynam

277 help to mitigate the emergence and spread of such strains.

278 Such strong swells are inferred to have created a number

279 Moreover, no such study has utilized RNA derived from bacterial biofi

280 hip between dysregulation of these areas and such symptoms has not been demonstrated.

281 to provide interface-specific information in such systems.

282 different pooling algorithms are unknown for such tasks.

283 el antiviral and immune modulatory therapies such that approval of new treatments can be linked to th

284 e described as maternal educational immunity such that by young adulthood, all immune cells respondin

285 creased peak ICa-L offsets increased SR load such that Ca(2+) release from the SR was maintained duri

286 structure, particularly in the ferric form, such that it is able to sample a broad conformational sp

287 ators that act nonredundantly in C. hirsuta, such that LFY has more obvious roles in floral and leaf

288 operties of the tissue connect across scales such that patterned disorder at the cellular level leads

289 syncratic variability in search performance, such that reaction times were longer when distractors ha

290 s a hierarchy among negative feedback loops, such that the effect of a negative feedback depends on i

291 ntation of the substrate prior to T1 closure such that the U5-A6 cleavage site becomes embraced to ac

292 As such, the design opportunities afforded by supramolecula

293 As such, they bridge traditional semiconductors, molecular

294 ction forces in motile tissues and show that such traction-based stresses match those calculated from

295 Such transient species are difficult to study experiment

296 th well established experimental values when such values exist, and they provide a large number of pr

297 ities that can aid in global surveillance of such viruses for potential spread and emerging threat to

298 thogenic avian influenza (HPAI) viruses, but such viruses' origins are often unclear.

299 dimensions and time, we show that imprinting such wavefunctions on electron pulses leads to shape-pre

300 chanisms that regulate stem cell fates under such widely varying conditions are not fully understood.