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4 have been used to perform these evaluations, such as a comparison of the total number of HRMS signals
6 s of the IFN-inducible PYHIN protein family, such as absent in melanoma-2 and IFN-gamma-inducible pro
9 ssion of ATP citrate-lyase levels in tissues such as adipose and liver, but the impact of diet on ace
10 of potential therapies for retinal diseases, such as age-related macular degeneration and inherited r
13 was helpful to annotate specific compounds, such as alkaloids, saponins, flavonoids, and terpenoids,
15 t functionalization of enaminone precursors, such as alkylation; 1,2- 1,3-, or 1,4-addition; and C-O
17 st the development of inflammatory diseases, such as allergy, asthma, and inflammatory bowel disease.
19 Previously proposed biological mechanisms, such as alterations in parasympathetic vagal tone, did n
20 uppressed the growth of all competing fungi, such as Alternaria, Epicoccum and Ulocladium species.
23 er analyses revealed that categorical labels such as amusement better capture reports of subjective e
24 on, whereas a less radical stabilizing group such as an alkyl or amide group at the C3-position of in
25 s for the medical proposes due to properties such as an elevated surface area and excellent electrica
27 increased understanding of the role factors such as an overactive innate immune response play in the
28 verages maintain their functional properties such as antioxidant, antibacterial and antitumoral activ
30 luence a variety of electro-chemical systems such as applications related to water splitting, catalys
31 the androgen receptor (AR) and AR variants, such as AR-V7, at their conserved SET/NAP domain, and ex
34 on, through regulating expression of targets such as ASB2 and RARA by reducing m(6)A levels in these
36 cal event in chronic inflammatory processes, such as atherosclerosis, but the control of the vascular
37 for DFT calculations of material properties such as atomic spin and orbital magnetic moments and loc
38 psychiatric and neurodegenerative diseases, such as autism spectrum disorder, depression and Alzheim
39 onal aspects of several biological processes such as autophagy, inflammation, proliferation and diffe
40 scovery of materials with target properties, such as auxetics, using high-throughput computations, op
41 tion and the expression of downstream genes, such as Bcl-2 (B-cell lymphoma 2), c-Myc, MMP7 (matrix m
42 t translate to sex-specific adverse outcomes such as behavioral deficits is a possibility that merits
43 not easily obtainable with other techniques, such as behavioral responses to pharmacological manipula
44 be responsive to various environmental cues, such as bile salts and alkaline pH, but how these factor
46 nents have demonstrated a range of functions such as bistability, oscillation, feedback, and logic ca
48 roteins and certain micronutrient biomarkers such as C-reactive protein (CRP), alpha-1-acid glycoprot
50 nators with relatively high quality factors, such as cantilevers vibrating in vacuum, can show charac
52 New drugs with novel mechanisms of action, such as cardiac myosin activators, are under investigati
54 well as the emergence of novel applications such as catalysis, electronics, nanomaterial synthesis a
55 osomal or multi vesicular body (MVB) markers such as CD81 and VPS4 and decreased co-localization with
57 tures unique to various modes of cell death, such as cells undergoing apoptosis versus necrosis/necro
58 fatty acids, metabolites, and complex lipids such as ceramides, glycerophosphoglycerols, cardiolipins
67 atures of cross-modal stimulus constituents, such as contrast, frequency, congruency, and temporal st
68 oordinating behaviour in a foraging ecology, such as cooperation, sex equality and egalitarianism.
69 -dipole interactions, which govern phenomena such as cooperative Lamb shifts, superradiant decay rate
70 sociated with chronic inflammatory diseases, such as COPD, in patients with hemoptysis, TAE of the BA
71 st alternative hydraulic architectural rules such as da Vinci's rule or Murray's rule, or physiologic
72 ablished arthropod-borne infectious diseases such as dengue and yellow fever and emerging diseases su
73 Microbial nitrogen transformation processes such as denitrification represent major sources of the p
75 ent to prevent some of the disease outcomes, such as development of bronchiectasis, anogenital dyspla
76 with lifestyle changes in Western societies, such as dietary modifications and increased antibiotic u
77 ompetition experiments using polar solvents, such as DMF, no "mixed" products possessing structurally
79 the strategies for increasing their strength such as doping with fine particles and alloying often si
80 viral therapy; HIV-associated comorbidities, such as dyslipidemia, drug abuse, and opportunistic infe
81 tep mechanism for HCCS, whereby HCCS mutants such as E159A are enhanced in release (step 4) of cyt c
83 figurable responses under external stimulus, such as electric fields and light radiation, have only r
85 (5'-diphosphates) in some signaling events, such as extracellular signal-regulated kinase 1/2 and la
87 havior in response to environmental changes, such as fluctuations in food abundance, to maximize surv
88 comprised of all ages, various backgrounds, such as from the community and skilled-nursing facilitie
89 lation, and discover distinguishing features such as gene sets and transcription factors that show di
92 influenced by perception of bitter compounds such as glucosinolates (GSLs) and isothiocyanates (ITCs)
94 f cyclic polyene perimeter-model approaches, such as Gouterman's four-orbital model and Michl's perim
96 nalytical alternatives might have advantages such as greater efficiency, more reproducibility and be
97 poor understanding of how mutations in genes such as GRN contribute to disease pathogenesis and neuro
99 suppressed agonist Emax) in signaling events such as guanosine 5'-3-O-(thio)triphosphate binding and
100 electrode during MES rely on: (i) mediators such as H2; (ii) physical contact through electron-trans
101 e sequenced samples, rather than public data such as HapMap or dbSNP, to train an accurate classifier
102 nge, making them unsuitable for applications such as heart-rate monitoring, which require a much lowe
103 odulation of ligand-gated chloride channels, such as hetero-oligomeric alpha1beta2gamma2 GABAA recept
104 d SUVs were compared with prognostic factors such as histologic grade (G1, G2, or G3, for low-grade [
106 This obscures answers to key questions, such as how tetrapods attained their tremendous extant d
107 distribution of the well-known Lewis pairs, such as how they are distributed in space and how their
108 rmal reproduction, particularly in a species such as humans with low population differentiation.
109 ulation of ILC2s by co-stimulatory molecules such as ICOS, regulatory T cells and by compounds such a
112 bit ubiquitous correlations in many aspects, such as individual and collective levels, temporal and s
114 previously unknown signatures of infection, such as induction of potassium channels and amino acid t
115 arr virus (EBV) poses numerous health risks, such as infectious mononucleosis and lymphoproliferative
116 The effects of different drying conditions, such as infrared power, drying air temperature and veloc
117 may support sensory aspects of the decision, such as interpreting the visual signals so that evidence
120 tundra productivity due to a common forcing, such as large-scale atmospheric circulation (North Atlan
122 been linked with adverse pregnancy outcomes such as low birth weight, stillbirth, and prematurity.
126 ron emission tomography (PET) radionuclides, such as manganese-52 ((52)Mn, T(1/2)=5.6days), allow the
127 consistent with primary magmatic processes, such as mantle heterogeneity or change in depth of melt
128 g high-throughput reporter assay experiments such as massively parallel reporter assays (MPRAs) and s
130 s, and are therefore needed for applications such as medical implants, tissue engineering, soft robot
131 om the geometrical cell-membrane properties, such as membrane curvature, volume, and surface area.
134 the reversible insertion of multivalent ions such as Mg(2+) and Al(3+) into electrode materials remai
135 , becoming clear that significant pathology, such as microglial activation, also takes place outside
139 ex on other complement-activating structures such as monosodium urate crystals and zymosan was not af
140 ar new drug using an intermediate end point, such as MRD, would require confirmation using traditiona
141 cortical area involved in distinct functions such as multimodal integration, movement initiation, bot
142 urodegenerative conditions affecting humans, such as multiple sclerosis, neuromyelitis optica spectru
143 s led to a search for alternative techniques such as multisite pacing, His bundle pacing, and endocar
148 hermore, CIPHER conducts downstream analysis such as: narrow and broad peak calling, peak annotation,
149 uding its interbreeding with other hominins, such as Neanderthals, and the ways in which natural sele
153 channels are involved in cellular responses such as neuronal bursting activity and cardiac rhythm.
155 nA is selectively depleted in myeloid cells, such as neutrophils, we show that FlnA negatively regula
156 therapeutic targeting of a signaling pathway such as NG2/CSPG4 may have different effects on cell beh
158 electrophilic nitro-fatty acids (NO2 -FAs), such as nitro oleic acid (OA-NO2 ) and nitro linoleic ac
160 ing flowering and grain filling using donors such as NL-44, will minimize the negative impact of heat
161 nt of cells with pharmacological inhibitors, such as nonsteroidal anti-inflammatory drugs or small in
162 r results suggest that Fe-rich clay minerals such as nontronite can form rapidly under oxidized condi
163 concentrations of monoamine neurotransmitter such as noradrenaline (NA) in living cells with simple,
165 s of overdispersed (evenly spaced) elements, such as North American Mima mounds, Brazilian murundus,
166 y sensitive to androgen-regulated AR action, such as NOV and ST6GalNAc1, were markedly altered, which
167 eration, and supplementation with precursors such as NR may be therapeutic in settings of acute liver
173 oney is also affected by many other factors, such as overfeeding of bees with sucrose, harvesting pri
174 d that IgE activation aligned with processes such as oxidative phosphorylation, angiogenesis, and the
175 MS is a unique feature of respiratory yeasts such as P. pastoris and C. albicans, and it may have nov
177 re implicated in neurodegenerative disorders such as Parkinson's disease (PD), it is important to exa
178 oach for the treatment of synucleinopathies, such as Parkinson's disease, dementia with Lewy bodies,
179 nctional neurosurgery for movement disorders such as Parkinson's disease, tremor, and dystonia involv
181 lls are a rich source of bioactive molecules such as peptides, hormones, and neurotransmitters, but r
182 ul weapons in the fight against foreign DNA, such as phages and plasmids, as well as a revolutionary
183 eraction between the electromagnetic fields, such as phase noises and spontaneous Raman scattering.
186 have been applied in development of systems such as photoresponsive materials, molecular motors, and
187 hildren because of exposure to plasticizers, such as phthalates, findings of previous studies are inc
188 iring chronic increase in energy production, such as physiologic or pathologic cardiac growth, remain
190 d by transcription elongation factors (TEFs) such as polymerase-associated factor 1 (Paf1), but it is
191 elated to a specific diagnosis), infections, such as polyomavirus-associated nephropathy, calcineurin
192 s can be uncovered by external perturbations such as pressure or magnetic field, which enhances the f
193 l disadvantages that can reduce sensitivity, such as probing only a small percentage of the nanoprobe
194 lar features and assigned them to categories such as proliferation-progenitor, proliferation-transfor
200 might involve modulatory regulatory factors such as R-spondin 1 (Rspo1), an extracellular protein th
201 detection is mainly based on large equipment such as readers and imaging systems, which require inten
205 d ventral tegmental area regulate behaviours such as reward-related learning, and motor control.
206 cts of ADH1B and ALDH2 on lifetime measures, such as risk of alcohol dependence, our study adds furth
208 it underlies all secondary genomic analyses such as RNA sequencing (RNA-Seq), chromatin immunoprecip
212 articularly applicable to migratory species, such as salmon, where distinct temporal changes in growt
213 e tool to guide the self-assembly of defects such as scars, pleats, folds, blisters, and liquid cryst
215 rtant when affecting habitat-forming species such as seagrasses, as the consequences on their abundan
216 ated because it displays fewer side effects, such as sedation and depression-like symptoms, than othe
218 as created numerous evolutionary innovations such as self-powered flight and its associated wings wit
219 ing behavior in the dynamical phase diagram, such as self-trapped localized motion, 2-D diffusive exp
220 challenging light-harvesting nanomaterials, such as semiconducting quantum dots (QDs), metal nanopar
221 gained considerable interest in applications such as sensors, detectors, energy harvesting cells, and
222 more feasible than other possible mechanisms such as single electron transfer, halogen atom transfer,
223 hene (FLG) systems on a dielectric substrate such as SiO2, the addition of each extra layer of graphe
226 he hypothesis that realistic land conditions such as soil moisture/soil temperature (SM/ST) can signi
229 variety of intron sequence-derived features, such as sparse profile, dinucleotide profile, position w
230 sing a set of cell type-independent features such as specific sequences recognized by the TFs and evo
232 can be used to control any dynamics engine, such as standard molecular dynamics and cell-modeling pa
233 work identifies simple synthetic parameters, such as stirring rate, that may be exploited to design o
234 nt with medications and confounding factors, such as substance use, previous adverse birth outcomes,
235 concentrations of recalcitrant contaminants such as sucralose, sulfamethoxazole and carbamazepine, w
236 ystems with predefined qualitative features, such as switching behaviour, bistability or oscillations
237 ons, but also in a diverse array of diseases such as systemic lupus erythematosus, diabetes, and canc
238 e magnetic resonance (MR) imaging modalities such as T1-weighted and diffusion-weighted MR imaging co
239 olled by a combination of multiple forcings, such as tectonics, sea-level fall and long-term decline
240 in new ways as well as to exogenous stimuli, such as temperature, magnetic field, and optical light.
241 variable water content and other parameters, such as temperature, that are inherent in natural erupti
243 titumor activities of immunomodulatory drugs such as thalidomide, lenalidomide, and pomalidomide, rec
244 novel insights on transcriptional regulation such as the "hit-and-run" model and transcription bursti
245 Downstream of gene expression, effectors such as the actomyosin contractile machinery drive embry
251 ion, we address new areas of lncRNA biology, such as the functions of enhancer RNAs, circular RNAs an
253 tion of effective process control procedures such as the Hazard Analysis Critical Control Point syste
257 ls, actin dynamics are regulated by kinases, such as the LIM domain kinase (LIMK), which regulates ac
263 , downward-skewed probability distributions, such as the skewed Student [Formula: see text] used here
264 Ca(2+) -sensitive potassium (K(+) ) currents such as the slowly activating delayed rectifier current
266 ve been elucidated, many questions remained, such as the structure-function relationship of monomeric
268 biomolecules include amyloidogenic peptides, such as the well-known amyloid-beta peptide involved in
271 e), thus in effect linking diverse exposures such as those from dietary intake and the microbiota wit
272 ently plastic to integrate multiple signals, such as those from microbes, damaged tissues, and the no
274 e expansions of short tandem repeats (STRs), such as those that cause amyotrophic lateral sclerosis (
277 enting colorectal cancer in high-risk groups such as those with familial adenomatosis polyposis (FAP)
278 ition, nonsemiconductor type photocatalysts, such as Ti-Si molecular sieves and carbon quantum dots (
279 thogen-activated Toll-like receptors (TLRs), such as TLR2 and TLR4, dimerize and move laterally acros
280 ng associations between orthogonal datasets, such as transcriptomic and metabolomics signatures, cell
281 er more labour intensive and costly methods, such as transplanting adult shoots, if disturbances are
283 label-free detection of explosive molecules such as trinitrotoluene (TNT) down to 10(-10)M in concen
286 Metabolic imbalance in chronic diseases such as type-1 diabetes may lead to detectable perturbat
287 -M78, and J-M267) and mitochondrial lineages such as U6b, in addition to common Eurasian haplogroups
288 sizes) under which virulent pathogen strains such as 'Ug99' (5,6) pose a threat from long-distance di
289 between MACL and markers of oxidative stress such as urinary methionine sulfoxide were observed in Hh
292 ecular explanation for how circadian phases, such as wake-sleep onset times, can become unstable in h
293 uman modification of streams through actions such as water abstraction is likely to further exacerbat
294 gh for observing subtle near-surface changes such as water content variations and permafrost alterati
295 differences suggest that extrinsic factors, such as water depth, contribute to behavioural sexual se
296 nd stored within capacitors for applications such as wireless and self-powered sensors or low-power e
297 an point to larger networks of interactions, such as with proteins that serve as hubs for essential c
298 ures targeted at specific vulnerable groups, such as women who experience PPD as a first psychiatric
299 efficiently constructed and candidate genes, such as Xa21 in rice, can be accurately and efficiently
300 engue and yellow fever and emerging diseases such as Zika and chikungunya, all of which are transmitt
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