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1 terization and quality analysis is no longer sufficient.
2 However, fusion alone is not sufficient.
3 poral resolution of 20 days are likely to be sufficient.
4 rance, and dietary and lifestyle advice, are sufficient.
5 i such as Toll-like receptor ligands was not sufficient.
7 r signaling pathways were analyzed in Mincle-sufficient and -deficient neutrophils stimulated in vitr
8 17 at a slow rate that is, nonetheless, both sufficient and necessary to explain the speed of pCPI-17
9 existing canon, dopamine transients are both sufficient and necessary to support this type of learnin
10 ned whether LRA treatment or ATI can provide sufficient antigenic stimulus to boost HIV-1-specific fu
11 nning the 7(th)-11(th) centuries CE) yielded sufficient autosomal genome coverage (0.21x to 3.93x) fo
12 demonstrates that the hypothalamic GLP-1R is sufficient but does not show whether it is necessary for
13 ere we show that IL-4 or IL-13 alone was not sufficient, but IL-4 or IL-13 together with apoptotic ce
14 tion via the Sec translocon, while retaining sufficient chemical and structural detail to capture man
16 s, without harming patient safety, providing sufficient compliance with standard precautions and ongo
20 e, 9.4-11.3 years; 93 females [50%]) who had sufficient data at the follow-up assessment for inclusio
21 ine FL therapy published after 1990 and with sufficient data to evaluate whether CR30 could predict t
22 Estimates at the 2.5 m(2) resolution provide sufficient details for highlighting and prioritizing are
23 prevention or treatment among PWID; provide sufficient details on the methods followed to allow crit
25 a vaccine, authorities were unable to secure sufficient doses to vaccinate the entire at-risk populat
26 s a clear impact on the population dynamics: sufficient drug pressure bears a clear signature of puri
27 neutral molecules, because they do not have sufficient electrons to give every bond an electron pair
31 ermore, we show that membrane recruitment is sufficient for Akt phosphorylation in response to growth
35 hesis does not occur in the cytosol at rates sufficient for DNA replication, supporting empirical dat
36 ults suggest that DSBs are necessary but not sufficient for efficient diRNA generation and a high lev
37 re spikes of nearly 1000 degrees C, which is sufficient for generating photoacoustic responses that c
39 phosphorylates H3S28 and it is necessary and sufficient for heterochromatin protein 1 binding and H3K
41 ion dataset of approximately 30000 peptides, sufficient for identifying the major sequence-specific f
42 tein (TBP) subunit of TFIID is necessary and sufficient for in vitro transcription, the TBP-associate
43 c, but not spatial, visuomotor congruence is sufficient for inducing multisensory integration, and im
45 the phagosome promotes hyphal morphogenesis, sufficient for induction of caspase-1-mediated macrophag
50 hether this sequence-specific interaction is sufficient for Myc's binding to its transcriptional targ
51 ngly, we show that either PARP1 or PARP2 are sufficient for near-normal XRCC1 recruitment at oxidativ
52 As E cell and gDN1 activity is necessary and sufficient for normal evening locomotor activity and day
53 d cAMP signaling molecules are necessary and sufficient for normal memory in intrinsic MB neurons.
54 ential for targeting to the mycomembrane and sufficient for OMP assembly into mycolic acid-containing
56 Endogenous hBD2 expression was required and sufficient for protection against V8 protease-mediated i
60 PACAP receptor activation was necessary and sufficient for stress-induced reinstatement of cocaine s
62 ariation of spring departure dates was still sufficient for the advancement of spring departure timin
63 mer meltwater to rivers and aquifers that is sufficient for the basic needs of 136 million people, or
65 ABS2 and ABS3 are each required and together sufficient for the robust cortical localization of the A
66 in within-host evolutionary dynamics can be sufficient for the virus to evolve intermediate viral lo
69 terol, ergosterol peroxide, is necessary and sufficient for Vms1 localization to mitochondria, throug
70 and Lamin B receptor (LBR) is necessary and sufficient for Xist spreading during X-chromosome inacti
72 nd that OvHV-2 glycoproteins B, H, and L are sufficient for, and viral glycoprotein Ov8 can significa
74 , with low-level residual NK cells providing sufficient help to allow optimal CD8 T cell proliferativ
76 men who are obese or overweight have not had sufficient impact on pregnancy and birth outcomes, which
78 ke of this rapid growth, clinicians may lack sufficient information about tCS to inform their clinica
80 ents and nurses perceived they had exchanged sufficient information for their own needs including pat
81 und that spectroscopy alone does not provide sufficient information to select candidate paper substra
84 Moreover, structural priming has now reached sufficient methodological maturity to provide substantia
89 important for the proteins that do not have sufficient number of homologous sequences to derive reli
90 of illuminating light is required to acquire sufficient number of photons for superior image quality.
91 rall, our results establish that Igf2 LOI is sufficient on its own to increase rates of neoplastic de
99 if large numbers of seed can be collected in sufficient quantity and delivered to restoration sites e
100 ts that the black hole is not accreting at a sufficient rate to make it electromagnetically bright an
102 netic resonance imaging (MRI) does not offer sufficient resolution to discriminate the notochord from
103 ation may be useful for institutions without sufficient resources to incorporate both stewardship app
105 ave been associated with response, they lack sufficient sensitivity and specificity for clinical use.
106 viously been developed, they did not provide sufficient sensitivity for imaging small neuronal compar
108 ertain that most children >4 y of age attain sufficient serum 25-hydroxyvitamin D [S-25(OH)D; i.e., >
109 compared with that of human graders and had sufficient specificity to make them cost-effective alter
110 rmed over five hundred simulations to obtain sufficient statistics to reveal the subtle effects of ch
111 ionally to its size, and 4) whether there is sufficient structural similarity between the two model s
112 prolonged MSC-T cell interactions needed for sufficient suppression of autoreactive T cells and helps
113 o an uncommitted client-SGTA complex, a self-sufficient targeting module, and an embedded but self-su
114 namics with increasing interest in obtaining sufficient temporal and spatial resolution to directly o
115 , the vulnerability and exposure of all data-sufficient terrestrial non-volant mammals (3,953 species
118 the present findings, we conclude that PS is sufficient to account for the perceptual organization of
119 mply knowing which neurons were activated is sufficient to accurately represent odor identity, with n
120 data and showed that small sample sizes were sufficient to achieve 80% power (16, 47, and 25 patients
121 ntaining 2-3 nmol Cl injected on-column were sufficient to achieve a precision (sigma) of 0.1 mUr (1
122 robed via second harmonic generation that is sufficient to achieve d33>10 pm V(-1), when incorporated
123 pre-malignant B cells, Myc overexpression is sufficient to activate BCR and PI3K/Akt signaling pathwa
124 ied PKC delta and varepsilon as required and sufficient to activate MAPK in GNAQ mutant melanomas.
126 ression of relatively few genes, but this is sufficient to adjust the configuration of the respirome
128 s normally restricted to tight junctions, is sufficient to alter apical membrane identity through its
129 ntact information for the subfamilies proves sufficient to assemble accurate structural models of the
130 ecisely targeted at the decision point, were sufficient to bidirectionally influence impulsive choice
131 ased VEGF expression and secretion to levels sufficient to blunt in vitro tube formation and prolifer
132 ly, artificial targeting of Fun30 to DSBs is sufficient to bypass the cell cycle regulation of long-r
133 otein, but not a fusion defective mutant, is sufficient to cause CO2 sensitivity, which can occur eve
134 egradation or fatty acid oxidation alone was sufficient to cause defective differentiation, while adm
135 ne 246 phosphorylation is both necessary and sufficient to cause exosome secretion without affecting
136 carrier can contain varying amounts of CCDs sufficient to cause false-positive test results up to 2
138 irmed that a Gln201Arg mutation in Wag31 was sufficient to cause resistance to APYS1, however, neithe
139 nstrate that an increase of SERT activity is sufficient to cause the apneas in Necdin-KO pups, and th
141 t GlyR alpha1(Q177K) subunit in vivo was not sufficient to compensate for a decrease in synaptic inte
142 (p17R76G), as in the S75X variant, is per se sufficient to confer a B-cell clonogenic potential to th
145 e studies in FL and DLBCL, with 800 mg being sufficient to consistently achieve durable response in M
146 Strikingly, water's large heat capacity is sufficient to control power output by storing excess ene
147 ma-tubulin ring complex (gamma-TuRC), and is sufficient to convert mitochondria to MTOCs independent
148 , MC3Rs expressed in Nkx2.1(+ve) neurons are sufficient to coordinate hypothalamic response and expre
151 ation in its ER-interacting LxxLL motifs was sufficient to delay tumor onset and to impair tumor grow
152 A one-dimensional array of these devices was sufficient to demonstrate an efficient Hamming distance
153 e square quadrats (i.e. 25 x 25 m) should be sufficient to detect B. pseudomallei at a given location
154 a CCS-based resolving power of >300 that is sufficient to differentiate analyte ions with CCS differ
155 ix-loop-helix proteins is both necessary and sufficient to direct cardiac mesoderm formation in frog
156 eting assays show that SecA is necessary and sufficient to direct the targeting and translocation of
157 efore, miR-338-3p depletion is necessary and sufficient to disrupt auditory TC signaling in 22q11DS m
159 NAi-mediated blockade of AKT, HSF1 or HuR is sufficient to downregulate Rictor and inhibit GBM growth
160 ng through one of its receptors, Ptger4, was sufficient to drive a differentiation state morphologica
161 en expressed in nontransgenic mice at levels sufficient to drive Abeta42 deposition, Abeta38 and Abet
162 soma of CA2 compared with CA1 PNs, which is sufficient to drive action potential output from CA2 but
163 mouse urothelial organoids, PPAR agonism is sufficient to drive growth-factor-independent growth in
164 al component of the BM microenvironment, was sufficient to drive hematopoietic aging phenotypes in yo
165 receptor NR4A1 in rhabdomyosarcomas that is sufficient to drive high expression of PAX3-FOXO1A there
166 we observed that Braf(V600E) activation was sufficient to drive ICC hyperplasia but not GIST tumorig
169 suggest that a small pool of active EGFRs is sufficient to drive tumorigenesis by signaling primarily
171 ortening in NOTCH1-haploinsufficient mice is sufficient to elicit age-dependent cardiovascular diseas
175 lts indicate that efficient ER export is not sufficient to enable normal cell-surface expression of T
177 uring the first week of a growth stimulus is sufficient to ensure long-term myofiber hypertrophy.
178 e amount of autonomy residents do achieve is sufficient to ensure readiness for the entire spectrum o
179 appeared mainly informal which did not seem sufficient to ensure that staff fully understood the tec
180 s across 10 studies demonstrated here is not sufficient to establish diagnostic accuracy of this tech
182 onstrates a central integration mechanism is sufficient to evoke painful thermal TCE, an essential st
183 residue on the DIV S2 helix was found to be sufficient to explain Pre1a's potent and selective inhib
184 we show that mixing between water masses is sufficient to explain the observed distribution of DOS,
185 ight barrier lowering, these two effects are sufficient to explain the observed emission current dist
187 imilar developmental stress is necessary and sufficient to extend Drosophila lifespan, and identify P
188 ol III in the gut of adult worms or flies is sufficient to extend lifespan; in flies, longevity can b
190 , but IDH1 overexpression in these cells was sufficient to fully restore chemoresistance under low nu
191 ids of purified excitatory interneurons were sufficient to generate oscillatory bursts with propertie
194 n of PMN-MPs into wounded colonic mucosa was sufficient to impair epithelial wound healing in vivo.
195 whether increased endogenous SL transport is sufficient to improve plant nutrition and productivity.
196 question is to determine whether OCN is also sufficient to improve these behaviors in wild-type mice,
197 romoter was strongly correlated with but not sufficient to increase ANO1 expression, suggesting methy
198 e desiccation tolerance, and these genes are sufficient to increase desiccation tolerance when expres
199 with environmental cystine, is necessary and sufficient to increase glutamine catabolism, defining im
201 using closed-loop optogenetic stimulation is sufficient to increase movement in the TST in stress-nai
202 f one allele of TSC2 in human fibroblasts is sufficient to increase p53 levels and impair stem cell r
204 -XL, known to block BIM and BMF, is not only sufficient to increase the viability of hematopoietic st
207 urthermore, ectopic expression of Pt-Ets4 is sufficient to induce cell delamination and migration by
210 Loss of SHP2 expression or activity was sufficient to induce fibroblast-to-myofibroblast differe
211 m of KRAS (KrasG12D) in pancreata of mice is sufficient to induce formation of pancreatic intraepithe
215 adenoma-like colonic epithelial cell line is sufficient to induce metabolic and gene expression profi
218 mpared with those in control tissue and were sufficient to induce OSM production (P < .001) in periph
219 uced EndoMT in vitro, Hey2 overexpression is sufficient to induce phenotypic conversion of endothelia
221 ression of Fat4 and Ds1 in the same cells is sufficient to induce polarization of Fat4-Ds1 complexes.
222 hat subarachnoid clots in sulci/fissures are sufficient to induce spreading depolarizations and acute
223 We aimed to achieve alpha-synuclein levels sufficient to induce terminal pathology without signific
224 We find that localized mechanical forces are sufficient to induce the formation of transcellular tunn
226 rmacologic targeting of SPHK1 or YAP/TAZ was sufficient to inhibit neuroblastoma metastasis in vivo O
228 s that activation of the Nrp2 gene in MCs is sufficient to instruct their circuit formation from the
231 dia added to mouse infant gut microbiota are sufficient to limit colonization of pathogenic Enterobac
232 ciated virus-short hairpin RNA construct was sufficient to markedly and persistently elevate ingestiv
233 y and to circadian centers in the brain, are sufficient to mediate both of these developmental proces
234 ed with genomic PSS sequences that were also sufficient to mediate PGBD5-induced DNA rearrangements i
237 we show that a fragmented draft assembly is sufficient to perform mapping-by-sequencing in nonmodel
238 ing of ROS-mediated PTP oxidation is not yet sufficient to predict the molecular responses of PTPs to
239 hing immune homeostasis, but they may not be sufficient to prevent tissue-specific autoimmune disease
240 e admixture, showing that a few centuries is sufficient to produce detectable genetic structure in hu
241 visible stimulus being viewed by one eye is sufficient to produce shifts in subsequent predominance
243 ine spacing, we show that a 2-mum spacing is sufficient to promote cell shape elongation and migratio
244 enetic experiments show that ectopic dATM is sufficient to promote DNA synthesis in wild-type fat bod
246 ors Wnt2b, Gremlin1, and R-spondin1, and are sufficient to promote maintenance of Lgr5(+) IESCs in in
248 n from the HRAS locus; repression of HRAS is sufficient to promote the transition of quiescent cells
250 ut not any of these kinases individually, is sufficient to protect neurons potently from degeneration
251 s of presymptomatic adolescent hAPP mice was sufficient to protect these mice from developing cogniti
252 ections have shown that antibodies alone are sufficient to provide broad protection against divergent
253 are functionally competent in vitro, and are sufficient to provide enhanced protection to infection w
254 usion of short fragments of EWSR1 to FLI1 is sufficient to recapitulate BAF complex retargeting and E
255 nd MMP-9 pharmacologically or genetically is sufficient to recapitulate transient synaptic potentiati
259 ion of beta2ARs only in airway epithelium is sufficient to rescue IL-13-induced AHR, inflammation, an
261 cyte-specific increase of Lsd1 expression is sufficient to rescue the age-related transition of beige
262 that over-expression of VEGF-A165 b alone is sufficient to rescue the increase in proteinuria, as wel
263 and demonstrate EIN2 C terminus (EIN2-C) is sufficient to rescue the levels of H3K14/23Ac of ein2-5
267 tic disease when DNA sequencing alone is not sufficient to reveal the underlying pathogenic mutation.
268 Rescuing these metabolic restrictions was sufficient to reverse IDH1-mediated radiosensitization.
269 e acid sequestration with cholestyramine was sufficient to reverse the observed heart dysfunction in
270 2334470 or the CDK2 inhibitor dinaciclib was sufficient to reverse these events and to restore the se
271 monstrate that loss of one allele of PTEN is sufficient to shift isoform dependency from p110alpha to
272 ief periods of anesthesia with propofol were sufficient to significantly increase bacterial burdens a
276 ster models suggest a single zinc ion may be sufficient to support phosphoethanolamine transfer.
278 suggest that environmental selection may be sufficient to suppress and stymy sexual conflict if it a
279 1 on MC38 colorectal adenocarcinoma cells is sufficient to suppress antitumor immunity, as deletion o
280 ting of the oncogenic MUC1 subunit MUC1-C is sufficient to suppress PD-L1 expression in TNBC cells.
282 se findings indicate that OCT4 expression is sufficient to sustain intrinsic signaling in a LIF-indep
283 N-terminal region of Tim10 is necessary and sufficient to target the substrate to the protease throu
284 d pressure conditions (7.4 GPa at 300 K) are sufficient to transform ammonia monohydrate from a proto
285 at the acquisition of a virulence plasmid is sufficient to transition beneficial symbionts to phytopa
286 anisms, Src family kinase (SFK) signaling is sufficient to transmit the CSF-1 lineage instructive sig
289 n that, when imposed in ectodermal cells, is sufficient to trigger their internalization without affe
290 protein, indicating that binding to MinD is sufficient to trigger this conformational transition in
291 ectly to latently infected monocytes was not sufficient to trigger viral reactivation which is likely
292 ue that directs people to forget one item is sufficient to wipe the corresponding trace from the hidd
293 ty of medical care may be necessary, but not sufficient, to improve the full range of medical outcome
295 rerequisites for OPV cessation, and ensuring sufficient vaccine supply to prevent and respond to outb
297 selective modulators of biomolecules without sufficient validation and then propagated in the scienti
298 aracteristics, such that they do not present sufficient variation to differentiate species by traditi
299 SO-29 treatment at P1, P5 or P15 resulted in sufficient vestibular recovery to support normal balance
300 ing shrub patches, at High Arctic sites with sufficient winter snow cover and ample water supply duri
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