ライフサイエンスコーパス: sugar transport

1 c GLUT1 are sufficient for ATP modulation of sugar transport.

2 he SGLT1 gene and to determine the defect in sugar transport.

3 two hypothetical models for protein-mediated sugar transport.

4 in human erythrocytes affect GLUT1-mediated sugar transport.

5 oes not fully account for the selectivity of sugar transport.

6 cific Enzyme IIA proteins in preparation for sugar transport.

7 by available hypotheses for carrier-mediated sugar transport.

8 r- and overestimated the rate of erythrocyte sugar transport.

9 influence insulin secretion, lipolysis, and sugar transport.

10 The observations are consistent with the sugar transport.

11 suppressor mutations that partially restored sugar transport.

12 ut inhibits ATP-modulation of GluT1-mediated sugar transport.

13 to MTSEA and MTSET, but not MTSES, abolished sugar transport.

14 ulation of 32 carbohydrate-active (CAZy), 61 sugar transport, 25 transcription factor and 234 C/HP ge

15 Nucleotide sugar transport across Golgi membranes is essential for

16 y that couples phosphoryl transfer to active sugar transport across the cell membrane.

17 GLUT1-catalyzed equilibrative sugar transport across the mammalian blood-brain barrier

18 r protein-protein interactions is coupled to sugar transport across the membrane.

19 Thus, LPG2 is required for nucleotide-sugar transport activity and probably encodes this Golgi

20 This study indicates that SWEETs retained sugar transport activity in all kingdoms of life, and th

21 proteoliposomes, where sodium dependence of sugar transport activity was demonstrated.

22 ve previously been shown to be essential for sugar transport activity.

23 eat gene Lr67 shows that how a plant manages sugar transport affects the ability of a broad group of

24 tion in the OHCs and on the observation that sugar transport alters the voltage sensitivity of the OH

25 resistance, (ii) repair of DNA damage, (iii) sugar transport and capsule biosynthesis, and (iv) two-c

26 system that controls catabolite repression, sugar transport and carbon metabolism in gram-positive b

27 to the periplasm to allow for extracellular sugar transport and closed to the cytoplasm.

28 tional properties were examined by measuring sugar transport and cotransporter currents.

29 an account for the complexity of erythrocyte sugar transport and its regulation by cytoplasmic ATP.

30 operon, those encoding proteins involved in sugar transport and metabolism, and remarkably, genes en

31 sins, and exonucleases as well as others for sugar transport and metabolism.

32 luxO mutant were involved in amino acid and sugar transport and metabolism.

33 esults demonstrate that the effects of CB on sugar transport and on cell motility and morphology invo

34 h allosteric regulation of human erythrocyte sugar transport and suggest that avian erythrocyte sugar

35 are responsible for the coupling of Na+ and sugar transport and that Q457 plays a critical role in s

36 inase may serve as a link between PTS-driven sugar transport and the electron transport chain.

37 s of the different superfamilies involved in sugar transport and the evolution of transporters in gen

38 itize carbohydrate utilization by modulating sugar transport and transcription of catabolic operons.

39 n enrichment of genes associated with carbon sugar transport and utilization and protein secretion, p

40 at shock proteins and regulators involved in sugar transporting and metabolism co-ordinated to enhanc

41 e changes in cell volume were measured under sugar-transporting and nontransporting conditions.

42 transporter, not previously associated with sugar transport, and in fact does not transport the suga

43 its 'greasy slide' aromatic residues during sugar transport, and suggest the involvement of L9, in t

44 ng proteoliposomes catalyze protein-mediated sugar transport, and the subsequent addition of solubili

45 nolate biosynthesis, cell wall modification, sugar transport, and transcriptional control are the key

46 oth parental GluT1- and GluT1.HA.H6-mediated sugar transport are acutely sensitive to cellular metabo

47 ansport are incorrect or (2) measurements of sugar transport are flawed.

48 This means that either (1) the models for sugar transport are incorrect or (2) measurements of sug

49 and nucleotide modulation of GluT1-mediated sugar transport are regulated by a proton-sensitive salt

50 lymorphisms P68L and T110I did not impact on sugar transport as assayed in Xenopus oocytes.

51 In sugar transport assays, mutant cells showed the striking

52 he present study we assess human erythrocyte sugar transport asymmetry by direct measurement of sugar

53 ntribute to the mechanistic understanding of sugar transport because the decisive role of the conserv

54 mulates blood-brain barrier endothelial cell sugar transport by acute up-regulation of plasma membran

55 acellular ATP inhibits human erythrocyte net sugar transport by binding cooperatively to the glucose

56 rporation but blocks acute modulation of net sugar transport by cellular metabolic inhibition.

57 the alternating access transporter model for sugar transport by confirming at least four GLUT1 confor

58 Na(+) and sugar transport by cotransporters (symporters) is though

59 Sugar transport by GLUT2 overexpressed in pituitary cell

60 adipocytes and Clone 9 cells, stimulation of sugar transport by puromycin, a translational inhibitor

61 Sugar transport by some permeases in Escherichia coli is

62 ier protein (HPr) is an essential element in sugar transport by the bacterial phosphoenolpyruvate:sug

63 ations of SGLT1 function; 3) the kinetics of sugar transport can be altered independently of influenc

64 Widespread expression of the eukaryotic sugar transport candidates suggests an important role in

65 GLUT1-HA-H6 confers GLUT1-specific sugar transport characteristics to transfected RE700A, i

66 indings support the hypothesis that red cell sugar transport complexity is host cell-specific.

67 Radiolabeled sugar transport confirmed transporter function and ident

68 ort during the periplasmic-open stage of the sugar transport cycle and the sugar is found to undergo

69 Possible roles for SFP1 in sugar transport during leaf senescence are discussed.

70 and Phe354 are determined to be important in sugar transport during the periplasmic-open stage of the

71 espite the documented kinetic alterations in sugar transport, epitope-tagged SGLT1 could promote abso

72 n system showed that hSGLT3 was incapable of sugar transport, even though SGLT3 was efficiently inser

73 Nucleotide binding and sugar transport experiments undertaken with dimeric and

74 Glucose is the main sugar transport form in animals, whereas plants use sucr

75 ter (the target), resulting in uncoupling of sugar transport from proton symport (the response).

76 to the galactose:H(+) symporter to uncouple sugar transport from proton symport.

77 e carrier) expressed in midgut that mediates sugar transport from the midgut lumen to hemolymph.

78 in functional characterization of nucleotide-sugar transports from this and other eukaryotes.

79 gene cassette replacing genes in a putative sugar transport gene cluster.

80 For example, the gene encoding sugar transport had the highest expression in the sapwoo

81 In humans, understanding sugar transport has therapeutic importance (e.g., addres

82 Most measurements of red cell sugar transport have been made over intervals of 10 s or

83 We suggest that GLUT1-mediated sugar transport in all cells is an intrinsically symmetr

84 ) phenyl m-hydroxybenzoate) inhibits passive sugar transport in human erythrocytes and cancer cell li

85 Inhibitors of protein synthesis stimulate sugar transport in mammalian cells through activation of

86 ed cell GluT1 but inhibits ATP modulation of sugar transport in resealed red cell ghosts and in GluT1

87 rg4p as a model for understanding nucleotide sugar transport in the Golgi.

88 esidue 454, in contrast, uncoupled Na(+) and sugar transport, indicating the importance of the negati

89 phloretin) or intracellular (cytochalasin B) sugar-transport inhibitors.

90 Many of these transporters are involved in sugar transport into yeast cells.

91 The complex process of phloem sugar transport involves symplasmic and apoplasmic event

92 o the kinetic variability of both cation and sugar transport is associated with cation binding.

93 Thus, not surprisingly, sugar transport is critical for plants, animals, and hum

94 This driving force of sugar transport is interrupted in fall when canopies are

95 We conclude either that human erythrocyte sugar transport is mediated by a carrier mechanism that

96 that GLUT1 (glucose transporter 1)-mediated sugar transport is mediated by an alternating access tra

97 Human erythrocyte sugar transport is mediated by the integral membrane pro

98 Avian erythrocyte sugar transport is stimulated during anoxia and during e

99 eraccumulate starch and sucrose, the soluble sugar transported long distance through the phloem of ve

100 The effects of ATP on GluT1-mediated sugar transport may be determined by the number of ATP m

101 fforts to increase productivity by enhancing sugar transport may disrupt the carbon-to-P homeostasis.

102 ots, and glucose flux in mutants affected in sugar transport, metabolism, and signaling.

103 Furthermore, Git1p contains a sugar transport motif and 12 potential membrane-spanning

104 The symbiotic efficiency of N. punctiforme sugar transport mutants was investigated by testing thei

105 ot interact with GluT1) is without effect on sugar transport over the same concentration range.

106 s demonstrate that water and urea follow the sugar transport pathway through SGLT1.

107 e identified and mutated residues lining the sugar transport pathway to cysteine.

108 ved in the interaction between the Na(+) and sugar transport pathways.

109 This model explains the uncoupled charge:sugar transport phenotype observed in wild type and G457

110 es of D-glucose as well as the inhibitors of sugar transport: phlorizin, deoxyphlorizin, and beta-D-g

111 hway variations were attributed to the amino sugar transport, phosphorylation, and deacetylation step

112 nzyme I of the phosphoenolpyruvate-dependent sugar-transporting phosphotransferase system (PTS) have

113 otein (HPr) is an essential component of the sugar-transporting phosphotransferase system (PTS) in ma

114 ty) is an important determinant of water and sugar transport, photosynthetic function, and biomechani

115 Here we demonstrate that sugar transport preference and kinetics can be rewired t

116 Human erythrocyte sugar transport presents a functional complexity that is

117 5-epimerase), the ATP binding cassette (ABC) sugar transport protein (wzt), and the O-antigen ligase

118 Enzyme IIC (EIIC) is a membrane-embedded sugar transport protein that is part of the phosphoenolp

119 a few proton-dependent transport of the STP (Sugar Transport Protein) and SUT/SUC (Sucrose Transporte

120 ) was inactive as a phosphoryl carrier and a sugar transport protein.

121 ose retrieval is mediated by the activity of sugar transport proteins (STPs).

122 to several amine, multidrug resistance, and sugar transport proteins of the major facilitator superf

123 Results showed that the maximum sugar transport rate of the phloem was limited by soluti

124 At its maximum sugar transport rate, the phloem functioned with a high

125 transport asymmetry by direct measurement of sugar transport rates and by analysis of the effects of

126 Two cysteine-less vSGLT proteins exhibited sugar transport rates comparable with that of the wild-t

127 We have examined acute sugar transport regulation in the murine brain microvasc

128 (2) Is ATP-GLUT1 interaction sufficient for sugar transport regulation?

129 The ryaA gene was renamed sgrS, for sugar transport-related sRNA.

130 g sites exist in 3T3 cells: sites related to sugar transport, sites related to cell motility and morp

131 transport and suggest that avian erythrocyte sugar transport suppression results from inhibition of c

132 n HPr from the phosphoenolpyruvate-dependent sugar transport system (PTS), and a cis-acting DNA seque

133 en, namely, rbsA, which codes for a putative sugar transport system ATP-binding protein, and vasK, a

134 hotransferase system (PTS), a multicomponent sugar transport system that phosphorylates the sugar as

135 code a periplasmic-binding-protein-dependent sugar transport system, and one (aglA) appears to encode

136 is a key protein in the phosphoenolpyruvate-sugar transport system.

137 tions with VirA but also interactions with a sugar transport system.

138 storage of sucrose excluded from a saturated sugar-transport system; peptide synthesis is reduced und

139 sport and degradation enzymes, but a loss of sugar transport systems and certain enzymes of sugar met

140 role in the regulation of activity of other sugar transport systems in Escherichia coli.

141 Allosteric regulation of several sugar transport systems such as those specific for lacto

142 The probable regulator of sugar transport systems, HPr(Ser) kinase, was demonstrat

143 the sugar-activated cation transport without sugar transport that occurs in hSGLT3.

144 ins in the phloem tissue that is involved in sugar transport throughout the plant, from leaves to roo

145 he Na+/glucose cotransporter (SGLT1) couples sugar transport to Na+ gradients across the intestinal b

146 ive SGLT1 transfectants, the apparent Km for sugar transport was increased 23-fold (313 microM to 7.3

147 The role of SAL0039 in sugar transport was supported by the inability of the sa

148 the key characteristics of secondary active sugar transport were maintained in both modes, namely, N

149 s, we show that SCR is primarily involved in sugar transport whereas SCL23 functions in mineral trans

150 fascicular phloem is largely responsible for sugar transport, whereas the extrafascicular phloem may

151 ve charge on residue 454 increased Na(+) and sugar transport with a normal stoichiometry of 2 Na(+):1