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1 es between Xenopus and mouse development and suggest the existence of 2 separate phases of vertebrate
3 karyotes appear to be conserved, the results suggest the existence of a bacteria-specific mechanism(s
5 nstrate a divergent activity of LpxTPa , and suggest the existence of a co-ordinated regulatory mecha
6 lve a long-standing fundamental question and suggest the existence of a codon usage code for protein
10 regulator of white-to-brown adipogenesis and suggest the existence of a coordinate regulation of adip
14 ical significance of TET oligomerization and suggest the existence of a functional regulation of the
16 with mutations in ERECTA family (ERf) genes suggest the existence of a GPI-AP in a branch of the ERf
21 ays that trigger episome loss from cells and suggest the existence of a little-understood mechanism t
22 o unfolded monomer between pH3 and pH 2, and suggest the existence of a low-populated, partially fold
29 livery at the base of the primary cilium and suggest the existence of a novel microtubule-based direc
31 f Amass -specific leaf area relationship, we suggest the existence of a photosynthetic stem economic
34 conservative, thermally activated motion, we suggest the existence of a rapid conservative athermal m
37 velopmental control of synapse stability and suggest the existence of a sensitive period of heightene
43 icrobial genomic information, which together suggest the existence of a vast oceanic phosphorus redox
44 a number of studies based on airway samples suggest the existence of a viable human lung microbiota.
47 ons between SOX9 and beta-catenin expression suggested the existence of a regulatory role for SOX9 ta
48 Despite this reduction, microarray analyses suggested the existence of a residual ABA signaling in r
50 long with a reduction in biological fitness, suggesting the existence of a "metabolic clock" that con
51 ural features in both enzymes are perturbed, suggesting the existence of a common mechanism for subst
52 mitochondrial respiration versus glycolysis, suggesting the existence of a common metabolic program a
53 decrease the longer cells are in quiescence, suggesting the existence of a continuum of quiescence de
54 nd the downstream tumor-suppressor activity, suggesting the existence of a counterbalancing role betw
55 Yet emerin null mice are essentially normal, suggesting the existence of a critical compensating fact
57 dent of changes in the extracellular domain, suggesting the existence of a distinct desensitization g
58 stance from the initial site of stimulation, suggesting the existence of a fast signal that propagate
59 en pre-synaptic proteins are over-expressed, suggesting the existence of a feedback circuit to match
60 nt-negative SGK1 suppresses mTOR activation, suggesting the existence of a feedforward loop between S
61 pression of many of these same marker genes, suggesting the existence of a general program in which e
62 ecorrelation of left- and right-ear signals, suggesting the existence of a highly integrative ILD-cod
63 eriments are in near-quantitative agreement, suggesting the existence of a line of maxima in kappaT (
64 be generated within the adult hypothalamus, suggesting the existence of a local neural stem/progenit
65 in CrtISO-Like1-/CrtISO-Like2-silenced ones, suggesting the existence of a metabolic side branch, com
66 with the A kinase anchoring protein AKAP150 suggesting the existence of a multiprotein signaling com
67 e and a repressor of IFN-gene transcription, suggesting the existence of a negative-feedback regulato
68 which was again restored by Bcl-x(s) siRNA, suggesting the existence of a novel mechanism by which B
69 to a lesser extent STAT3 in hCMEC/D3 cells, suggesting the existence of a positive feedback loop bet
70 oint Cluster Region pseudogene (BCRP) block, suggesting the existence of a possible recombination hot
71 n-plane ordering and low molecular mobility, suggesting the existence of a previously unknown 2D soli
72 uced by IL-5 was completely blocked by IL-4, suggesting the existence of a previously unknown antagon
73 actory to remating within seconds [1, 3, 4], suggesting the existence of a rapid mechanism to prevent
74 nal motor domain still labeled microtubules, suggesting the existence of a second microtubule binding
75 g return to normal when the wound is healed, suggesting the existence of a specific clearance mechani
76 present in Lotus japonicus and Glycine max, suggesting the existence of a specific conserved class o
77 longation of the mother centrosomes in GSCs, suggesting the existence of a stem cell-specific centros
78 s-modal signal in a frequency-selective way, suggesting the existence of a supramodal temporal bindin
79 allele revealed a sharp gene dosage effect, suggesting the existence of a threshold of TGF-beta1 sig
80 ib is necessary to prevent tumor recurrence, suggesting the existence of a vismodegib-resistant reser
81 perturbation of plastid protein homeostasis suggests the existence of a chloroplast-to-nucleus signa
82 ation of RNA triple helices inside cells and suggests the existence of a class of triple-stranded RNA
83 nome in the context of other ancient samples suggests the existence of a common ancient genomic signa
84 d IIB also decreases contact guidance, which suggests the existence of a compensatory mechanism betwe
85 namic in fMRI fear-conditioning studies-also suggests the existence of a coordinated brain response p
92 ity and Wigner crystalization, which in turn suggests the existence of a new strongly correlated elec
93 utations in the viral protein 3C(pro), which suggests the existence of a novel functional interaction
95 for otherwise-excluded nucleic acids, which suggests the existence of a protein-mediated trafficking
97 chronic lymphocytic leukemia (CLL) patients suggests the existence of a regulatory network that rest
100 iety of cellular functions regulated by Slt2 suggests the existence of a significant number of still
101 l but consistent changes common across tasks suggests the existence of a task-general network archite
102 paucity of classical sigma70-type promoters, suggesting the existence of activators that compensate f
103 modification score and heritability analyses suggest the existence of additional genetic modifiers, s
104 of specific protein-DNA binding and strongly suggest the existence of additional recognition mechanis
105 roperties reflect the activity of HERV-K and suggest the existence of additional unique loci within h
106 ills CCR5-deficient cells, like neutrophils, suggesting the existence of additional cellular receptor
107 pears to be recessively transmitted in mice, suggesting the existence of additional factors in the pa
108 oma risk in <40% of melanoma-prone families, suggesting the existence of additional high-risk genes o
109 mutants where MglA localizes symmetrically, suggesting the existence of additional regulators that c
110 ity than expected for heterozygous probands, suggesting the existence of additional TTN mutations.
112 as a specific propensity to Th2 programming, suggesting the existence of altered skin immune signalin
113 t in dopamine transporter knock-out animals, suggesting the existence of alternative amphetamine targ
114 snoRNA) transcripts independently of Drosha, suggesting the existence of alternative DGCR8 complex(es
115 on and function in mouse platelets, strongly suggesting the existence of alternative mechanisms of ta
117 origin recognition complex are viable, which suggests the existence of alternative mechanisms to init
118 ding hair bundles from the Bullfrog sacculus suggest the existence of an active process that might un
119 in a human auditory discrimination task and suggest the existence of an adaptive mechanism that trac
120 philins B and C in ER redox homeostasis, and suggest the existence of an additional ER oxidative path
129 n of plesiosaurs than previously thought and suggest the existence of an optimal ecomorphology for sh
132 hosphorylation of TrkC detected in our study suggested the existence of an autocrine signaling loop i
136 despite a complete absence of SPAK and OSR1, suggesting the existence of an alternative activating ki
137 osphorylated NKCC2 abundance was still high, suggesting the existence of an alternative activating ki
138 tional ubiquitylation occurs at a low level, suggesting the existence of an alternative route for del
139 us mutations similar to MMR-bearing species, suggesting the existence of an alternative to the canoni
140 on was dependent on reactive oxygen species, suggesting the existence of an autocrine amplification l
141 R) were significantly higher in transgenics; suggesting the existence of an efficient antioxidant def
142 d deletions within an 85-amino-acid segment, suggesting the existence of an incorporation domain.
143 nked to elastic cytoskeletal stresses, which suggests the existence of an adaptive mechanism that pro
145 ed on Chiloe Island in southern Chile, which suggests the existence of an endemic focus in South Amer
147 ot increase the strength or stiffness, which suggests the existence of an optimal degree of hierarchy
148 es are encoded in the corynebacterial genome suggests the existence of an oxidative protein-folding p
151 SCO4 is localized to the chloroplasts, which suggests the existence of an unreported type of protein
152 omes is not autophagy dependent and strongly suggests the existence of another lipid delivery pathway
153 ubiquitin, but genetic and biochemical data suggest the existence of at least one other substrate re
156 t least two different distribution patterns, suggesting the existence of at least two distinct mechan
157 growth substrate used as sole carbon source, suggesting the existence of at least two systems for pyr
158 around photosystem I, and mounting evidence suggests the existence of at least partial division of d
159 regulation of bone mass exerted by the brain suggests the existence of bone-derived signals modulatin
161 repertoire of the H1 family of proteins and suggests the existence of chromatin retention factors fo
164 uscle mass are highly correlated in mammals, suggesting the existence of common anabolic signaling ne
165 ns were partially inhibited by RGD peptides, suggesting the existence of common RGD-containing bindin
166 ESC differentiation but not self-renewal and suggests the existence of context-specific H3K4 methylat
169 between individual variation and stereotypy, suggesting the existence of dedicated mechanisms that si
171 ast four bands with strong oxidase activity, suggesting the existence of different PPO isoforms.
172 l in the expression of some OmpR targets and suggest the existence of differential regulation within
173 genetically diverse populations of neurons, suggesting the existence of discrete classes of cells.
176 independent PTI against RKNs in A. thaliana, suggesting the existence of diverse nematode recognition
177 ialized oxyporines from the Early Cretaceous suggests the existence of diverse Agaricomycetes and a s
178 nd demagnetisation-based shape anisotropies, suggesting the existence of Dzyaloshinskii-Moriya-based
179 l events to the mental position of the self, suggesting the existence of egocentric mapping in both d
182 rough chromatin in vivo is highly efficient, suggesting the existence of factors that overcome this o
183 freshwater to marine regions of the estuary suggested the existence of five estuarine salinity fish
187 e found for comparisons of motion direction, suggesting the existence of generalized neural mechanism
188 ce are almost completely protected, strongly suggesting the existence of genetic interactions between
190 ectronic structure analysis of these systems suggested the existence of hidden divalent N(I) characte
192 icro- and nanostructural examination of LBPs suggests the existence of high levels of structural comp
193 the segregation of the two vesicular types, suggesting the existence of highly regulated mechanisms
195 amines lack efficacy in treating itch in AD, suggesting the existence of histamine-independent itch p
196 termini of the Gle2 binding domain sequence, suggesting the existence of "hotspots" for this protein-
199 ysregulation induced by the n-alkanol series suggested the existence of interaction pockets of define
200 teristic in X-ray photoemission spectroscopy suggests the existence of interlayer interaction between
201 Clinical and epidemiological studies have suggested the existence of intermediate factors that may
204 eening without knowledge of the target), and suggest the existence of labile assembly machines that c
205 tests, and ecological niche models (ENM) and suggested the existence of LGM refuges within mountain r
207 vels reflect the codon usage of viral genes, suggesting the existence of local tRNA pools optimized f
208 yday activity, such as when walking on sand, suggests the existence of long-term motor memories.
209 phic NucS in a M. smegmatis surrogate model, suggests the existence of M. tuberculosis mutator strain
210 ts, affecting from ten to hundreds of genes, suggesting the existence of master genetic regulators.
212 modalities require distinct subpopulations, suggesting the existence of modality-specific labeled li
213 clamp region of RyR are ligand-dependent and suggest the existence of multiple ligand dependent RyR a
216 onse and association with clinical outcomes, suggesting the existence of multiple atopy phenotypes.
217 lue of Delta(17)O = 0.330 +/- 0.011 per mil, suggesting the existence of multiple oxygen reservoirs o
218 K reverses the cell's response to the anode, suggesting the existence of multiple signaling pathways
221 and is rapidly transported to the cytoplasm, suggesting the existence of myosin XI-driven nucleocytop
222 n to HIV-infected mothers acquire the virus, suggesting the existence of naturally protective immune
223 autonomous theory of network homeostasis and suggest the existence of network-wide regulation rules.
228 aB (NF-kappaB) pathway, but previous studies suggested the existence of NF-kappaB-independent functio
230 ed by the inhibition of viral DNA synthesis, suggesting the existence of novel and potent regulatory
231 stitutive internalization of LGR5 to the TGN suggests the existence of novel biochemical roles for it
232 of splice variants lacking a signal peptide suggests the existence of novel intracellular isoforms.
234 RNA regions to engage in multi-interactions suggests the existence of one or more molecular RNA swit
235 cted by the deletion of TDG from the zygote, suggesting the existence of other demethylation mechanis
236 t eliminate Cdc42 accumulation at the front, suggesting the existence of other recycling pathways.
238 ptic AMPA-type glutamate receptors (AMPARs), suggesting the existence of overlapping molecular mechan
240 abscission is delayed but can be completed, suggesting the existence of parallel membrane-reorganizi
241 t from Rtt109-dependent dosage compensation, suggesting the existence of pathways excluding specific
242 r the lack of mitochondrial PE biosynthesis, suggesting the existence of PE transport pathway from ER
244 ur of six PAR genes identified, and our data suggest the existence of polymorphisms maintained by bal
246 n red blood cells (RBCs), which lack nuclei, suggesting the existence of post-translational cellular
247 orm discrete roles during plant development, suggesting the existence of PRC1 variants; however, it i
249 Data sets from high-throughput sequencing suggest the existence of previously unidentified bacteri
250 y 58 coronary artery disease (CAD) loci that suggest the existence of previously unsuspected new biol
251 suppress the formation of ER-inclusion MCS, suggesting the existence of redundant mechanisms in MCS
252 may be less severe than is usually believed, suggesting the existence of referral bias in testing pat
253 ants undertake to synthesize chlorophyll and suggests the existence of regulation, possibly involving
254 fficient only in preclinical trials and have suggested the existence of resistance mechanisms with th
258 tected with very low frequency in the blood, suggesting the existence of separate compartments of T c
259 s of rhodopsin-expressing photoreceptors and suggest the existence of several circuits for rhodopsin-
261 Although there is considerable evidence suggesting the existence of short- and long-distance mov
262 the activation of these energetic pathways, suggesting the existence of signaling mechanisms that ad
264 aben analogues in sediment and sludge, which suggested the existence of similar sources of origin for
266 rably between affected and unaffected sites, suggesting the existence of small fibre neuropathy in sy
269 uman and animals have differential dynamics, suggesting the existence of species-specific regulators
270 pletion without affecting mitochondria mass, suggesting the existence of specific mitochondrial pathw
271 navigate the environment, and previous work suggests the existence of specific sensory mechanisms to
272 y, at least in the range of notes tested and suggest the existence of statistical priors for notes wi
275 d fruits, some accessions carry round fruit, suggesting the existence of suppressors of OVATE in the
277 lly significant impact on telomere function, suggesting the existence of "telo-miRNAs" that have an i
280 mpacts on the brown adipogenic phenotype and suggests the existence of the NAT8L-driven NAA metabolis
282 fruits silenced at different metabolic steps suggested the existence of three functional units, compr
284 d in multicellularity genes and their tRNAs, suggesting the existence of transcriptional programs coo
287 f the publication in this journal of a model suggesting the existence of 'tumour progenitor genes'.
288 xternal appearance, i.e. the body image, and suggest the existence of two functionally separate repre
291 ironment, but reduced fitness when combined, suggesting the existence of two peaks on the fitness lan
292 rect semi-quantitative analysis of bleaching suggests the existence of two membrane-bound Dystrophin
293 ximately 500 hTERT molecules per HeLa cell), suggesting the existence of unassembled components.
294 g the importance of temporal variability and suggesting the existence of uncharacterized sources.
295 ors only partially impairs heat nociception, suggesting the existence of undiscovered mechanisms.
296 eem to be mutually excluded from each other, suggesting the existence of unknown granule-targeting me
298 ypically arteries--to reach their endorgans, suggesting the existence of vascular guidance cues that
300 receptor was not affected in TMTC KO cells, suggesting the existence of yet another O-Man glycosylat
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