ライフサイエンスコーパス: suicidality

1 em (any anxiety, depression, or self-harm or suicidality).

2 osure were associated with increased risk of suicidality.

3 specific phobia, severe role impairment, and suicidality.

4 ly expressed gene biomarkers of relevance to suicidality.

5 the prevalence ratio (PR) was calculated for suicidality.

6 wnstream pathways related to inflammation in suicidality.

7 sychiatric comorbidity, role impairment, and suicidality.

8 psychiatric disorders, role impairment, and suicidality.

9 lationship appears to exist between NSSI and suicidality.

10 ed circadian rhythms and a high incidence of suicidality.

11 follow-up on all measures of depression and suicidality.

12 inst placing a black box warning on AEDs for suicidality.

13 ing the exact onset and duration of NSSI and suicidality.

14 dolescent nonsuicidal self-injury (NSSI) and suicidality.

15 y influences the risk for treatment-emergent suicidality.

16 order, for association with new or worsening suicidality.

17 SNPs revealed a gene-by-sex interaction with suicidality.

18 significantly associated with improvement in suicidality.

19 were significantly associated with new-onset suicidality.

20 fe events, severity of major depression, and suicidality.

21 t patterns, aberrant behavior, appetite, and suicidality.

22 isorders were not proximally associated with suicidality.

23 associated with a modestly increased risk of suicidality.

24 increased risk of adverse events, including suicidality.

25 ing their potential utility as biomarkers of suicidality.

26 icularly for enhanced clinical monitoring of suicidality.

27 red evaluations that included assessments of suicidality.

28 t of manic or depressive symptoms, or reduce suicidality.

29 ontrol, sexual risk behavior, pregnancy, and suicidality.

30 order were associated with a higher level of suicidality.

31 e withdrawal symptoms such as depression and suicidality.

32 s were significantly associated with current suicidality.

33 m ratings were significantly associated with suicidality.

34 l threshold depression rating that predicted suicidality.

35 % for predicting future hospitalizations for suicidality.

36 nt subgroups and subgroups with a history of suicidality.

37 onale for its possible use in treating acute suicidality.

38 ction of psychiatric hospitalizations due to suicidality.

39 nd postmortem brain samples of patients with suicidality.

40 ors, was one of the increased biomarkers for suicidality.

41 ts that suicide terrorism is attributable to suicidality.

42 psies, is that suicide attacks are caused by suicidality.

43 ck of efficacy or worsening of depression or suicidality.

44 knowledge of risk and resilience factors for suicidality.

45 r disorder), a high-risk population prone to suicidality.

46 ndividuals, such as those with some level of suicidality.

47 sive episode, 35.4% and 14.7%, respectively; suicidality, 20.2%; generalized anxiety disorder, 7.9%;

48 rders (30.6% [N=22] versus 10.7% [N=3]), and suicidality (22.2% [N=16] versus 3.6% [N=1]).

49 istical superiority to treatment as usual on suicidality (23% versus 74%), diagnostic status (13% ver

50 t by 18 studies comprising 583 patients with suicidality, 315 patients without suicidality, and 845 h

51 , in Finns, TPH genotype was associated with suicidality, a pathophysiological mechanism that may inv

52 previous depressive episodes, male sex, and suicidality additionally predicted poor 1-year outcomes.

53 ased risk of completed suicide and to assess suicidality adequately in patients with chronic fatigue

54 treatment of depression in late life and how suicidality affects treatment response.

55 ealth would be significantly associated with suicidality after adjusting for mental health variables

56 ical health is significantly associated with suicidality, after adjusting for depression, was specifi

57 olymorphism in intron 7 of the TPH gene with suicidality, alcoholism, and the Karolinska Scales of Pe

58 ce abuse and depressive symptoms (other than suicidality), all of the suicidality measures remain sig

59 Suicidality also was reduced significantly (P < .05).

60 Twenty-nine participants (12.83%) reported suicidality, although only 11 of these were significantl

61 18 identified over 90% of the patients with suicidality, although there was also a high rate of fals

62 REB1 were associated with treatment-emergent suicidality among men with depression, extending an obse

63 a platform for identifying genetic risk for suicidality among PLWHA.

64 This study documents the burden of nonfatal suicidality among US blacks, notably Caribbean black men

65 ug Administration issued a warning regarding suicidality and antiepileptic drugs based on meta-analys

66 phic effects, are decreased in expression in suicidality and are known targets of the anti-suicidal m

67 Studies also investigated suicidality and cultural factors underlying coping.

68 ings for many depressive symptoms (including suicidality and depressed mood) and lower ratings for th

69 Outcomes included suicidality and diagnoses of depression, anxiety disorde

70 ed to test the relative associations between suicidality and dimensional and categorical depression m

71 s review will provide a brief description of suicidality and discuss the contribution of upstream and

72 showed significant and similar reductions in suicidality and functional impairment.

73 We examined associations between suicidality and genotypes that predict plasma efavirenz

74 cidality compared with both patients without suicidality and healthy control subjects (p < .05 for ea

75 cidality compared with both patients without suicidality and healthy controls (p < .01 for each).

76 , he puts sole focus on the personal side of suicidality and ignores the individual's context.

77 o the TPH gene may predispose individuals to suicidality and other behaviors thought to be influenced

78 okine levels in patients with versus without suicidality and patients with suicidality versus healthy

79 oyment, and making progress in symptoms like suicidality and self-harming.

80 luded questions relating to the phenomena of suicidality and sexual abuse, to test the hypothesis tha

81 ant feature of several psychiatric diseases, suicidality and violent behaviour.

82 CFI-S, Convergent Functional Information for Suicidality) and for anxiety and mood (SASS, Simplified

83 ients with suicidality, 315 patients without suicidality, and 845 healthy control subjects.

84 suicidal predisposition, indicated by prior suicidality, and controlling for prior psychiatric disor

85 empters display more severe psychopathology, suicidality, and interpersonal difficulties and are more

86 including BPD symptomatology, mood symptoms, suicidality, and neurocognitive impairment.

87 cide ideation, use of crisis services due to suicidality, and reasons for living.

88 Forty percent of transgender persons endorse suicidality, and the rate of self-injurious behavior and

89 and IL-6 were most robustly associated with suicidality, and these cytokines may help distinguish su

90 borrowing and indebtedness, legal problems, suicidality, and treatment for mental health and gamblin

91 rtant as emerging evidence suggests NSSI and suicidality are distinct yet related clinical phenomena

92 gies diverse, but symptoms such as guilt and suicidality are impossible to reproduce in animal models

93 selective serotonin reuptake inhibitors and suicidality are presenting major difficulties for clinic

94 Four lifetime symptoms of suicidality as measured by the Diagnostic Interview Sche

95 e episode, generalized anxiety disorder, and suicidality, as well as presence and severity of postdep

96 stration reports regarding increased risk of suicidality associated with AED treatment, the current s

97 symptom load explained most of the risk for suicidality associated with current psychiatric disorder

98 groups of patients based on their levels of suicidality at baseline and during treatment (those with

99 were included in the risk ratio analysis of suicidality because 4 trials had no events in the drug o

100 ication or whether such medication decreases suicidality because of improvements in insomnia.

101 and after diagnosis (IRR, 2.2-10.9) and for suicidality before epilepsy diagnosis (IRR, 3.1-4.5) and

102 sue of biological context and differences in suicidality between the two genders.

103 viduals that are more homogenous in terms of suicidality biology and behavior.

104 chiatric disorder is a major risk factor for suicidality but has poor positive predictive value.

105 ficant positive association between AEDs and suicidality but voted against placing a black box warnin

106 dditionally, we examined whether subtypes of suicidality can be identified based on mental state at t

107 apps, Convergent Functional Information for Suicidality (CFI-S) and Simplified Affective State Scale

108 associated with a 2-fold increased hazard of suicidality compared with a regimen without efavirenz.

109 nd postmortem brain samples of patients with suicidality compared with both patients without suicidal

110 was significantly decreased in patients with suicidality compared with both patients without suicidal

111 mainly by melancholic symptoms, retardation, suicidality, depersonalization, typical diurnal variatio

112 after co-occurring psychiatric disorders and suicidality during adolescence were controlled statistic

113 nted for by co-occurring Axis I disorders or suicidality during adolescence.

114 he risk for Axis I psychiatric disorders and suicidality during early adulthood.

115 pression, substance abuse), higher levels of suicidality (e.g., ideation), and poorer interpersonal f

116 .7; for 1999, OR, 3.9; 95% CI, 1.9-7.8), and suicidality (eg, attempted suicide [for 1997, OR, 7.6; 9

117 ding pain, was significantly associated with suicidality even after adjusting for treatment and depre

118 not associated with increased depression or suicidality events compared with placebo.

119 d a Public Health Advisory about the risk of suicidality for pediatric patients taking antidepressant

120 suicide, and a rating of "much worsening of suicidality" from baseline.

121 f access to guns at home was associated with suicidality (grades 9-12: P<.001) and violence (grades 7

122 Notably, PER1, increased in expression in suicidality, had an AUC of 84% for predicting future hos

123 The suicidality hypothesis could be applied to other situati

124 shed much needed light in the area of female suicidality, identify useful objective predictors and he

125 study of BDD's course, the authors examined suicidality in 185 subjects for up to 4 years.

126 ity Rating Scale (AIRS), and its relation to suicidality in a high-risk sample.

127 ing whether treatment of insomnia may reduce suicidality in adults with depression.

128 on as an important potential risk factor for suicidality in adults with this condition.

129 thors' knowledge, has prospectively examined suicidality in BDD.

130 (i.e., mixed state), that is associated with suicidality in bipolar patients.

131 d and Drug Administration warnings regarding suicidality in children, adolescents, and young adults m

132 nosis of psychosis, depression, anxiety, and suicidality in each of the 3 years before and after the

133 association of the TPH 17 779C (L) allele to suicidality in impulsive offenders reported previously w

134 ion (SI) and for future hospitalizations for suicidality in independent cohorts, leading to the ident

135 r, LHFP appears to be a strong predictor for suicidality in males with depression.

136 r disorder were studied to determine whether suicidality in mania is associated with increasing depre

137 s risk for antidepressant treatment-emergent suicidality in men with major depressive disorder, but i

138 d clinical information (apps) predictors for suicidality in men.

139 otional withdrawal, counter the emergence of suicidality in patients with schizophrenia spectrum diso

140 ed that the 2004 black box warning regarding suicidality in pediatric patients receiving antidepressa

141 d a public health advisory about the risk of suicidality in pediatric patients taking selective serot

142 d a public health advisory about the risk of suicidality in pediatric patients taking selective serot

143 e measurement of both sexual orientation and suicidality in population-based samples.

144 t activity have been noted to be a marker of suicidality in psychiatric patients.

145 The authors' goal was to examine suicidality in relation to acute symptom remission in in

146 essive symptoms, diagnosable depression, and suicidality in relation to stressful life events than in

147 ciated with susceptibility to depression and suicidality in response to stressful life events.

148 s predictions of future hospitalizations for suicidality in the bipolar cohort (receiver-operating ch

149 moved and physicians confront depression and suicidality in their peers, they are more likely to reco

150 oute induced a rapid improvement in mood and suicidality in these refractory depressed patients, supp

151 de), our apriori primary end point, predicts suicidality in women.

152 ased risk of suicidal ideation and behavior (suicidality) in pediatric patients.

153 ressants and suicidal behavior and ideation (suicidality) in youth, adverse events from pediatric cli

154 future as well as past hospitalizations with suicidality, in a live cohort of bipolar disorder subjec

155 rs to predict future hospitalizations due to suicidality, in male bipolar disorder participants.

156 Suicidality incidence per 1000 person-years was 8.08 (47

157 ality disorder, substance use disorders, and suicidality (including recurrent thoughts of death, suic

158 justed analyses based on 12 genotype levels, suicidality increased per level in exposed (hazard ratio

159 re inversely proportional to the severity of suicidality independent from depression severity.

160 imply that whenever past or current NSSI or suicidality is identified, primary care clinicians condu

161 Suicidality is linked to mental pain, which is modulated

162 Suicidality is linked with mixed manic states and may be

163 ance abuse, sexual activity, depression, and suicidality is needed with appropriate anticipatory guid

164 The relationship between efavirenz use and suicidality is not well-defined.

165 its high prevalence and known risk factors, suicidality is often undetected.

166 infections to neuropsychiatric symptoms and suicidality is only beginning to be explored.

167 Report Questionnaire expanded to include two suicidality items from 810 displaced women living in ref

168 Unrecognized and thus untreated suicidality leads to substantial morbidity and mortality

169 sting drugs used to treat mood disorders and suicidality (lithium, clozapine and omega-3 fatty acids)

170 dentify blood gene expression biomarkers for suicidality, looking at differential expression of genes

171 OR, 26.7 [95% CI, 4.3-52.5]; P < .001), and suicidality (males only; OR, 18.5 [95% CI, 6.2-55.1]; P

172 Overall, suicidality may be underlined, at least in part, by biol

173 ity, difficulties in emotion regulation, and suicidality may characterize adolescent expression of bo

174 h ARRB1 and GSK3B decreases in expression in suicidality may provide a synergistic mechanistical corr

175 ymptoms (other than suicidality), all of the suicidality measures remain significantly associated wit

176 is significantly associated with each of the suicidality measures.

177 as moderate to high risk suicidality on the suicidality module of the Mini Neuropsychiatric Intervie

178 ction of psychiatric hospitalizations due to suicidality (n=24).

179 asures, considered an indicator of "clinical suicidality." Neither objective severity of depression n

180 High suicidality, nonsuicidal self-injury, and poor family fu

181 ers (odds ratio=1.65, 95% CI=1.25-2.18), and suicidality (odds ratio=2.21, 95% CI=1.47-3.31) than the

182 l health disorder, subthreshold symptoms, or suicidality on all three study occasions (sustained good

183 rticipants, 124 (8.6%) subsequently reported suicidality on at least 1 visit; these individuals were

184 cidal risk (defined as moderate to high risk suicidality on the suicidality module of the Mini Neurop

185 association between socioeconomic status and suicidality or depressed mood reported at each week of t

186 onal capacity, quality of life, reduction of suicidality or hospitalizations, and harms.

187 ssession [OR, 5.6; 95% CI, 1.7-18.3]), prior suicidality [OR, 2.9; 95% CI, 1.7-4.9], aspects of prior

188 ing a history of any mental health disorder, suicidality, or any combination of the 2.

189 had adverse reactions related to self-harm, suicidality, or harm to others.

190 of >/= 4; hospitalization for depression or suicidality; or discontinuation for lack of efficacy or

191 authors assessed patients' past and current suicidality, other psychopathology, treatment, and remis

192 ificantly associated with treatment-emergent suicidality overall.

193 e showed significant evidence for linkage to suicidality (P=.006 in unaffected sib pairs), severe sui

194 ), mood (especially, depression, apathy, and suicidality), personality and behavior (especially poor

195 = .52, p = .005; ACC: r = .53, p = .004) and suicidality (PFC: r = .40, p = .037; ACC: r = .38, p = .

196 markers that have all around evidence (track suicidality, predict it, are reflective of biological pr

197 story of mental illness without a history of suicidality (prevalence ratio [PR], 1.13; 95% CI, 0.98-1

198 ethodical, anchored approach to categorizing suicidality provides an accurate and comprehensive ident

199 cessation itself or reflects depression and suicidality rates in smokers, independent of treatment.

200 d be designed to assess whether increases in suicidality result from CNS impairments from a given hyp

201 , prioritization and validation for tracking suicidality, resulting in a Top Dozen list of candidate

202 Suicidality risk at T2 appeared similarly elevated, but

203 eta-analysis was conducted to obtain overall suicidality risk estimates for each drug individually, f

204 pport of previously published biomarkers for suicidality (SAT1, MARCKS and SKA2).

205 disturbance, including risk-taking behavior (suicidality, self-mutilation, and sexual aggression).

206 seline of severe depression, manic symptoms, suicidality, subsyndromal mood episodes, and sexual abus

207 identified novel potential therapeutics for suicidality, such as ebselen (a lithium mimetic), pirace

208 ts or biomarkers for drugs known to mitigate suicidality, such as omega-3 fatty acids, lithium and cl

209 ut leukotriene receptor-modifying agents and suicidality/suicide, but because these were based on cas

210 composite measure of reporting at least one suicidality symptom was also assessed.

211 tients hospitalized without specification of suicidality, the lifetime risk of suicide was 4.0%.

212 Women are under-represented in research on suicidality to date.

213 The relationship of physical well-being to suicidality underscores the need for a multidisciplinary

214 Univariate analyses found suicidality unrelated to age or sex but positively assoc

215 chiatric symptoms, psychosis, depression, or suicidality using a gradual titration (1-mg daily dose).

216 ere significantly decreased in patients with suicidality versus control subjects (p < .05).

217 versus without suicidality and patients with suicidality versus healthy controls.

218 fficult-to-treat components (e.g. cognition, suicidality, violence) of the illness.

219 y significantly higher levels of dependency, suicidality, violence, impulsivity, substance use proble

220 ce of suicide in those ever hospitalized for suicidality was 8.6%.

221 Relation to suicidality was assessed by regression of suicide attemp

222 ceptual abnormalities, poor orientation, and suicidality was associated with an increased risk for ho

223 rticipants to efavirenz-containing regimens; suicidality was defined as reported suicidal ideation or

224 Suicidality was defined as suicidal ideation or attempte

225 Among 1833 participants, suicidality was documented in 41 in exposed analyses, an

226 Suicidality was more common in mixed than manic bipolar

227 that insight may be associated with greater suicidality was partially supported.

228 atus of the TPH A779C allele as a marker for suicidality was replicated and linkage with alcoholism a

229 Suicidality was unrelated to age, age at diagnosis, sex,

230 ers, major depressive disorder, and rates of suicidality were determined and compared for individuals

231 der, recent mental health specialty care, or suicidality were excluded.

232 PRINCIPAL FINDINGS: Patients presenting with suicidality were recruited from the Emergency Department

233 Past, current, and recurrent suicidality were significantly more common among patient

234 iated with impairment in role functioning or suicidality were strong predictors of perceived need.

235 nergy, minimal sleep disruption, and greater suicidality, while typical-onset patients had more sever

236 L2, predicted future hospitalizations due to suicidality with an AUC of 89%, and the panel of 50 vali

237 50) predicted future hospitalizations due to suicidality with an AUC of 94%.

238 0.98-1.29) and adolescents with a history of suicidality with or without a history of mental illness

239 sories regarding the potential for pediatric suicidality with selective serotonin reuptake inhibitor

240 tudies were too small or too short to assess suicidality with SSRIs or SNRIs.

241 Five studies investigated self-harm or suicidality, with conflicting results.