ライフサイエンスコーパス: sulfhydryl oxidase

1 recently discovered enigmatic flavin-linked sulfhydryl oxidase.

2 h protein disulfide bonds in thioredoxin and sulfhydryl oxidase.

3 ases and is related to the ERV/ALR family of sulfhydryl oxidases.

4 on to the earlier reports of metal-dependent sulfhydryl oxidases.

5 , PRDX4, and the candidate oxidants quiescin-sulfhydryl oxidase 1 (QSOX1) and vitamin K epoxide reduc

6 sion (SAGE) databases was enzyme quiescin Q6 sulfhydryl oxidase 1 (QSOX1).

7 ing that the C-X-X-C motif was essential for sulfhydryl oxidase activity and responsible for the alte

8 lly, the assay is used to show that there is sulfhydryl oxidase activity in a number of secretory flu

9 ted from chicken egg white and found to have sulfhydryl oxidase activity with a range of small molecu

10 92 C(155)XXC(158) amino acids, important for sulfhydryl oxidase activity, were mutated to A(155)XXA(1

11 ns no detectable FAD, and shows undetectable sulfhydryl oxidase activity.

12 n excellent substrate of the enzyme quiescin-sulfhydryl oxidase and may find utility in the character

13 These data show that sulfhydryl oxidase and protein disulfide isomerase can c

14 ells, the assay could detect 15fmol of avian sulfhydryl oxidase and the rates were linearly dependent

15 family of flavin adenine dinucleotide-linked sulfhydryl oxidases and is related to the ERV/ALR family

16 luble 62 kDa FAD-linked and EDTA-insensitive sulfhydryl oxidase apparently constitutes the dominant d

17 The sulfhydryl oxidase augmenter of liver regeneration (ALR)

18 ysteine and selenomethionine residues in the sulfhydryl oxidase augmenter of liver regeneration (ALR)

19 and depend on the oxidoreductase Mia40, the sulfhydryl oxidase augmenter of liver regeneration (ALR)

20 he cysteine residues are rapidly oxidized by sulfhydryl oxidase, but activity is efficiently restored

21 Sulfhydryl oxidase can also oxidize reduced protein disu

22 sitive, continuous fluorescence assay of the sulfhydryl oxidases can be devised with careful selectio

23 Metal- and flavin-dependent sulfhydryl oxidases catalyze the generation of disulfide

24 Both metal and flavin-dependent sulfhydryl oxidases catalyze the net generation of disul

25 Both metalloprotein and flavin-linked sulfhydryl oxidases catalyze the oxidation of thiols to

26 ial flavin adenine dinucleotide (FAD)-linked sulfhydryl oxidase Erv1 (essential for respiration and v

27 Reoxidation of Mia40 is facilitated by the sulfhydryl oxidase Erv1 and the respiratory chain.

28 The sulfhydryl oxidase Erv1 partners with the oxidoreductase

29 ctions involving disulfide transfer from the sulfhydryl oxidase Erv1 to Mia40 and from Mia40 to subst

30 us pathway with the oxidoreductase Mia40 and sulfhydryl oxidase Erv1, termed the mitochondrial interm

31 t that Tim17 can be directly oxidized by the sulfhydryl oxidase Erv1.

32 hen in excess or at a lower rate by only the sulfhydryl oxidase Erv1.

33 In contrast, the flavin-linked sulfhydryl oxidase from Aspergillus niger is related to

34 The flavin-dependent sulfhydryl oxidase from chicken egg white catalyzes the

35 The flavin-dependent sulfhydryl oxidase from chicken egg white catalyzes the

36 These metazoan sulfhydryl oxidases have four recognizable domains: a re

37 A physiological role for sulfhydryl oxidase in the formation of disulfide bonds i

38 Erv1 is a flavin-dependent sulfhydryl oxidase in the mitochondrial intermembrane sp

39 AD prosthetic group of the ERV/ALR family of sulfhydryl oxidases is housed at the mouth of a 4-helix

40 reinvestigation of the metal content of skin sulfhydryl oxidases is warranted.

41 oth the egg white enzyme and a flavin-linked sulfhydryl oxidase isolated from bovine semen.

42 Two of these (quiescin-sulfhydryl oxidase-like and adenosine 5'-phosphosulfate

43 with the augmenter of liver regeneration, a sulfhydryl oxidase of the mitochondrial intermembrane sp

44 ies between members of the ERV/ALR family of sulfhydryl oxidases provides insights into their likely

45 Flavoproteins of the quiescin/sulfhydryl oxidase (QSOX) family catalyze oxidation of p

46 es the substrate specificity of the quiescin sulfhydryl oxidase (QSOX) family of disulfide-generating

47 The quiescin sulfhydryl oxidase (QSOX) family of enzymes generates di

48 ge) showed it to be a member of the Quiescin-sulfhydryl oxidase (QSOX) family.

49 Quiescin sulfhydryl oxidase (QSOX) flavoenzymes catalyze the dire

50 in sequence shows it belongs to the Quiescin/sulfhydryl oxidase (QSOX) flavoprotein family.

51 The flavin-dependent quiescin-sulfhydryl oxidase (QSOX) inserts disulfide bridges into

52 The flavoprotein quiescin-sulfhydryl oxidase (QSOX) rapidly inserts disulfide bond

53 tein containing the ERV/ALR domain, quiescin-sulfhydryl oxidase (QSOX).

54 Flavin-dependent sulfhydryl oxidases represent a newly discovered family

55 neration (ALR) is both a growth factor and a sulfhydryl oxidase that binds FAD in an unusual helix-ri

56 Erv2p is a small, dimeric FAD-dependent sulfhydryl oxidase that generates disulfide bonds in the

57 1-like (Gfer) is an evolutionarily conserved sulfhydryl oxidase that is enriched in embryonic and adu

58 ngs to the ERV1/ALR family of FAD-containing sulfhydryl oxidases that use oxygen as the electron acce

59 wn to be a substrate of the flavin-dependent sulfhydryl oxidases, there is little quantitative inform

60 The first mammalian sulfhydryl oxidase to be described was an iron-dependent

61 Chicken egg white sulfhydryl oxidase utilizes an internal redox-active cys

62 understood flavoenzyme may not function as a sulfhydryl oxidase within the mitochondrial intermembran