ライフサイエンスコーパス: sulfite oxidase

1 rsulfide dioxygenase (ETHE1), rhodanese, and sulfite oxidase.

2 ubstrate binding and oxidation of sulfite by sulfite oxidase.

3 is remarkably similar to the low-pH form of sulfite oxidase.

4 he proposed structure of the high-pH form of sulfite oxidase.

5 nd capable of donating bound MPT to MPT-free sulfite oxidase.

6 concomitantly with the insertion of MPT into sulfite oxidase.

7 proteins: cytochrome c, adenylate kinase and sulfite oxidase.

8 calculations are extended to oxo transfer by sulfite oxidase.

9 mutation was also generated in cloned human sulfite oxidase.

10 t, 9 closely resembles the oxidized sites in sulfite oxidase and assimilatory nitrate reductase as de

11 ing partial misfolding and monomerization of sulfite oxidase and attenuating both substrate binding a

12 persulfide dioxygenase (PDO), rhodanese, and sulfite oxidase and converts H2S to thiosulfate and sulf

13 Saccharomyces cerevisiae lacking sulfite oxidase and deleted of flavohemoglobin showed an

14 ed the characteristic absorption spectrum of sulfite oxidase and exhibited steady state and rapid kin

15 of the isolated molybdenum domains of native sulfite oxidase and of the R160Q mutant showed significa

16 are sufficient for the insertion of MPT into sulfite oxidase and the conversion of MPT into Moco in t

17 s in crystallizing recombinant human and rat sulfite oxidases and the failure to clone the chicken su

18 e reductase as deduced from crystallography (sulfite oxidase) and Mo EXAFS.

19 sulfite oxidase, Arabidopsis thaliana plant sulfite oxidase, and the bacterial sulfite dehydrogenase

20 MPT-free human sulfite oxidase apoprotein was obtained by heterologous

21 remarkably similar to that found in chicken sulfite oxidase, Arabidopsis thaliana plant sulfite oxid

22 Sulfite oxidases are metalloenzymes that oxidize sulfite

23 The physiological implications of plant sulfite oxidase as a copious generator of superoxide are

24 The crystal structure of chicken liver sulfite oxidase at 1.9 A resolution reveals that each mo

25 onance Raman spectra of oxidized A. thaliana sulfite oxidase catalytically cycled in both H2(16)O and

26 The molybdenum-containing enzyme sulfite oxidase catalyzes the conversion of sulfite to s

27 Sulfite oxidase catalyzes the terminal reaction in the d

28 We synthesized the gene for chicken sulfite oxidase de novo, working backward from the amino

29 Isolated sulfite oxidase deficiency (ISOD) causes severe intellec

30 Four variants associated with sulfite oxidase deficiency have been identified: two mut

31 in the sulfite oxidase gene responsible for sulfite oxidase deficiency in a 5-year-old girl was iden

32 Sulfite oxidase deficiency is a lethal genetic disease t

33 In humans, sulfite oxidase deficiency is an inherited recessive dis

34 tations identified in patients with isolated sulfite oxidase deficiency, the G473D variant is of part

35 for confirmatory testing of cystic fibrosis, sulfite oxidase deficiency, urolithiasis, and other diso

36 crystal structures of the wild type and the sulfite oxidase deficiency-causing R138Q (R160Q in human

37 The active sites of the xanthine oxidase and sulfite oxidase enzyme families contain one pterin-dithi

38 Human sulfite oxidase expressed in E. coli moeA(-) could be ac

39 MogA was incapable of activating sulfite oxidase expressed in E. coli mogA(-).

40 affecting the type of reactions catalyzed by sulfite oxidase family enzymes.

41 ctive sites in fully oxidized members of the sulfite oxidase family.

42 The Mo(V) center of plant sulfite oxidase from Arabidopsis thaliana (At-SO) has be

43 Plant sulfite oxidase from Arabidopsis thaliana has been chara

44 Sulfite oxidase from Arabidopsis thaliana has been reduc

45 Several point mutations in the sulfite oxidase gene have been identified from patients

46 n molybdenum cofactor biosynthesis or in the sulfite oxidase gene itself.

47 The mutation in the sulfite oxidase gene responsible for sulfite oxidase def

48 xidases and the failure to clone the chicken sulfite oxidase gene.

49 A comprehensive kinetic study of sulfite oxidase has been undertaken over the pH range 6.

50 Sulfite oxidases have been wired to electrode surfaces,

51 nter of the pathogenic R160Q mutant of human sulfite oxidase (hSO) confirms the presence of three dis

52 dies on the pathogenic R160Q mutant of human sulfite oxidase (HSO) have shown that Mo-heme intramolec

53 hotosystem I, cytochrome c (cyt c) and human sulfite oxidase (hSOX).

54 ent response of the catalytic cycle of human sulfite oxidase immobilized on an electrode.

55 0Q in humans) variant of recombinant chicken sulfite oxidase in the resting and sulfate-bound forms.

56 ble to reconstitute molybdopterin (MPT)-free sulfite oxidase in vitro with the molybdenum cofactor (M

57 Analysis of recombinant G473D sulfite oxidase indicated that it is severely impaired b

58 The crystal structure of chicken liver sulfite oxidase indicated that this residue, Cys185 in c

59 of the wild-type dimeric state of mammalian sulfite oxidase is not yet well understood.

60 e reductive half-reaction of wild-type human sulfite oxidase, k(red)(heme) changed very little over t

61 he first time in rapid reaction assays using sulfite oxidase lacking the N-terminal heme-containing d

62 subsequent reconstitution of MoCo-free human sulfite oxidase-molybdenum domain yielding a fully activ

63 were performed on wild-type and Y343F human sulfite oxidase over the pH range 6-10.

64 te forms of the molybdenum-containing enzyme sulfite oxidase possess a b-type cytochrome prosthetic g

65 Sulfite oxidase purified from the moeA(-) lysate was als

66 Genetic deficiency of sulfite oxidase results in neurological abnormalities an

67 f this residue in the catalytic mechanism of sulfite oxidase, serine and alanine variants at position

68 A sulfite oxidase (SO(X)) (EC 1.8.3.1) purified from Syzyg

69 d low pH (lpH) forms of native chicken liver sulfite oxidase (SO) and recombinant human SO have been

70 Protein film voltammetry of chicken liver sulfite oxidase (SO) bound at the pyrolytic graphite "ed

71 Sulfite oxidase (SO) catalyzes the physiologically criti

72 8D were identified in patients with isolated sulfite oxidase (SO) deficiency, and the equivalent amin

73 Dimethylsulfoxide reductase (DMSOR) and sulfite oxidase (SO) families were the most widespread m

74 Sulfite oxidase (SO) is a vitally important molybdenum e

75 Arginine 160 in human sulfite oxidase (SO) is conserved in all SO species sequ

76 Tyrosine 343 in human sulfite oxidase (SO) is conserved in all SOs sequenced t

77 Sulfite oxidase (SO) is found in animals and plants, whi

78 The Mo(V) state of the molybdoenzyme sulfite oxidase (SO) is paramagnetic and can be studied

79 sulfate reductase and the sulfite scavengers sulfite oxidase (SO), sulfite reductase, UDP-sulfoquinov

80 relate to the reduced and oxidized forms of sulfite oxidase (SO).

81 f this residue in the catalytic mechanism of sulfite oxidase, steady-state and stopped-flow analyses

82 Sulfite oxidase (SUOX) expression and the drug-transport

83 o either the xanthine dehydrogenase (XDH) or sulfite oxidase (SUOX) families, and these have pyranopt

84 In the crystal structure of chicken sulfite oxidase, the residue Tyr(322) (Tyr(343) in human

85 to emanate from my laboratory have been the sulfite oxidase, the several superoxide dismutases, the

86 In vertebrate sulfite oxidases, the electrons generated at the Mo cent

87 Peroxisomal sulfite oxidase transcripts and activity levels are like

88 s the reason for the decrease in activity of sulfite oxidases upon immobilization.

89 In steady-state assays of Y343F sulfite oxidase using cytochrome c as the electron accep

90 In this study, we have investigated IET in sulfite oxidase using laser flash photolysis as a functi

91 heme and molybdenum centers of chicken liver sulfite oxidase varies from approximately 20 to 1400 s(-

92 Each of the four cysteines in rat sulfite oxidase was altered by site-directed mutagenesis

93 ybdate in the reconstitution mixture, active sulfite oxidase was obtained, revealing that in vitro MP

94 Native sulfite oxidase was rapidly inactivated by phenylglyoxal

95 ther bovine serum albumin or Moco-containing sulfite oxidase was used in place of aposulfite oxidase.

96 ase, the residue Tyr(322) (Tyr(343) in human sulfite oxidase) was found to directly interact with a b

97 the role of conformational changes on IET in sulfite oxidase, which helps to clarify the inconsistenc