ライフサイエンスコーパス: sulfoxide reductase

1 -sulfoxide reductase) and MsrB (methionine-R-sulfoxide reductase).

2 ide reductase, peroxiredoxin, and methionine sulfoxide reductase.

3 rsed by coexpression with peptide methionine sulfoxide reductase.

4 d by a ubiquitous enzyme, peptide methionine sulfoxide reductase.

5 ersed by treating the enzyme with methionine sulfoxide reductase.

6 idized protein was incubated with methionine sulfoxide reductase.

7 f stereospecific enzymes known as methionine sulfoxide reductases.

8 that are catalyzed by endogenous methionine sulfoxide reductases.

9 of glutathione peroxidase 1 and methionine-R-sulfoxide reductase 1 in the liver, suggesting partial s

10 xidase, ascorbate peroxidase, and methionine sulfoxide reductase 2) are slightly up-regulated.

11 KII inhibition, overexpression of methionine sulfoxide reductase A (an enzyme that reduces oxidized C

12 Methionine sulfoxide reductase A (MsrA) catalyzes the reduction of

13 The enzyme peptide methionine sulfoxide reductase A (MSRA) catalyzes the repair of oxi

14 Methionine sulfoxide reductase A (MsrA) is an antioxidant repair en

15 Methionine sulfoxide reductase A (MsrA) is an enzyme involved in re

16 Methionine sulfoxide reductase A (MsrA) maintains the function of m

17 Methionine sulfoxide reductase A (MsrA) repairs oxidized methionine

18 ant form of M. genitalium lacking methionine sulfoxide reductase A (MsrA), an antioxidant enzyme whic

19 CaMKII oxidation is reversed by methionine sulfoxide reductase A (MsrA), and MsrA-/- mice show exag

20 be reversed through the action of methionine sulfoxide reductase A (MsrA), which is implicated in oxi

21 in (NT domain) is fused to tandem methionine sulfoxide reductase A and B domains (MsrA/B).

22 strate almost absent catalase and methionine sulfoxide reductase A and B protein expression via immun

23 ) method for the determination of methionine sulfoxide reductase A and methionine sulfoxide reductase

24 Methionine sulfoxide reductase A is an essential enzyme in the anti

25 Methionine sulfoxide reductase A is an essential enzyme in the anti

26 Lipidation of methionine sulfoxide reductase A occurs in the mouse, in transfecte

27 led the redox relay mechanisms of methionine sulfoxide reductase A of the pathogen Corynebacterium di

28 uctase, glutathione reductase and methionine sulfoxide reductase A proteins were significantly up-reg

29 of only glutathione reductase and methionine sulfoxide reductase A proteins were significantly up-reg

30 ling by targeting the antioxidant methionine sulfoxide reductase A to modulate liposarcoma cell survi

31 cted transgenic overexpression of methionine sulfoxide reductase A, an enzyme that reduces oxidized C

32 oxide dismutase (SOD2), catalase, methionine sulfoxide reductase A, and the 20S proteasome subunits P

33 ues of diverse targets, including methionine sulfoxide reductase A, myosin light chain kinase, and Ru

34 er-expression of a repair enzyme, methionine sulfoxide reductase A, rendered them resistant, suggesti

35 ylated and nonmyristoylated mouse methionine sulfoxide reductase A.

36 idues in proteins is catalyzed by methionine sulfoxide reductases A (MSRA) and B (MSRB), which act in

37 In normal healthy human skin, methionine sulfoxide reductases A and B specifically reduce methion

38 epaired in the human epidermis by methionine sulfoxide reductases A and B, respectively.

39 MSRAs (methionine sulfoxide reductases A) are enzymes that reverse the eff

40 activation of HypT depends on the methionine sulfoxide reductases A/B.

41 ional selenoproteins, including methionine-S-sulfoxide reductase, a selenoprotein specific to Chlamyd

42 iform selenium deficiency because methionine sulfoxide reductase activities were similar in mice and

43 cleus and exhibited the highest methionine-R-sulfoxide reductase activity because of the presence of

44 y, the soluble 83-kDa enzyme retained biotin sulfoxide reductase activity using reduced methyl violog

45 ) were essential for MoCo-dependent dimethyl sulfoxide reductase activity, suggesting that these prot

46 reduced pyridine nucleotide-dependent biotin sulfoxide reductase activity.

47 nsible for this function: MsrA (methionine-S-sulfoxide reductase) and MsrB (methionine-R-sulfoxide re

48 e reductase, Rhodobacter capsulatus dimethyl sulfoxide reductase, and Shewanella massilia trimethylam

49 Peptide methionine sulfoxide reductases are conserved enzymes that reduce o

50 Methionine sulfoxide reductases are conserved enzymes that reduce o

51 Methionine sulfoxide reductases are key enzymes that repair oxidati

52 Methionine-sulfoxide reductases are unique, in that their ability t

53 hionine sulfoxide reductase A and methionine sulfoxide reductase B activities in mouse liver is descr

54 f inactivated GroEL by the enzyme methionine sulfoxide reductase B/A (MsrB/A).

55 onjunction with Mical proteins, methionine-R-sulfoxide reductase B1 (MsrB1) regulates mammalian actin

56 We further expressed mouse methionine sulfoxide reductase B1 (MsrB1), a selenoenzyme that cata

57 lamine-N-oxide reductase (TMAOR), and biotin sulfoxide reductase (BSOR) are members of a class of bac

58 cter sphaeroides f. sp. denitrificans biotin sulfoxide reductase (BSOR) catalyzes the reduction of d-

59 Rhodobacter sphaeroides biotin sulfoxide reductase (BSOR) contains the bis(molybdopteri

60 d that expression of yeast free methionine-R-sulfoxide reductase can fully compensate for this defici

61 cter sphaeroides f. sp. denitrificans biotin sulfoxide reductase catalyzes the reduction of d-biotin

62 Enzymes belonging to the bacterial dimethyl sulfoxide reductase (DMSOR) family contain a metal-bis-p

63 of bis-molybdopterin enzymes of the dimethyl sulfoxide reductase (DMSOR) family.

64 ed with those of previously studied dimethyl sulfoxide reductase (DMSOr) models.

65 tic intermediate in the reaction of dimethyl sulfoxide reductase (DMSOR) with (CH(3))(3)NO has been p

66 Dimethyl sulfoxide reductase (DMSOR), trimethylamine-N-oxide redu

67 cofactor in Rhodobacter sphaeroides dimethyl sulfoxide reductase (DMSOR).

68 plastidial thiol peroxidases and methionine sulfoxide reductases employing a single cysteine residue

69 Methionine sulfoxide reductase enzymes MsrA and MsrB have complemen

70 f recombinant Rhodobacter sphaeroides biotin sulfoxide reductase expressed in Escherichia coli.

71 gnificant homology to the peptide methionine sulfoxide reductase family of enzymes, specifically MsrA

72 s protein is the only member of the dimethyl sulfoxide reductase family of molybdopterin enzymes that

73 ydrogenase is a novel member of the dimethyl sulfoxide reductase family of molybdopterin-containing e

74 olybdenum containing enzymes of the dimethyl sulfoxide reductase family.

75 tudies of the molybdenum-containing dimethyl sulfoxide reductase from Rhodobacter sphaeroides have yi

76 eversion of knockout mutations in the biotin sulfoxide reductase gene, bisC, has 64% base sequence id

77 cter sphaeroides f. sp. denitrificans biotin sulfoxide reductase has been heterologously expressed in

78 sely related MGD-containing enzyme, dimethyl sulfoxide reductase, has indicated a number of conserved

79 are fused to form a bifunctional methionine sulfoxide reductase (i.e., MsrBA) enzyme.

80 and oxidized apoA-I treated with methionine sulfoxide reductase implicate oxidation of specific tyro

81 expression of Rhodobacter sphaeroides biotin sulfoxide reductase in Escherichia coli were modified, r

82 haracteristic supports a role for methionine sulfoxide reductase in redox signaling.

83 repair of oxidized calmodulin by methionine sulfoxide reductase induces comparable changes in alpha-

84 However, the identity of all methionine sulfoxide reductases involved, their cellular locations

85 the active site cysteine of mouse methionine sulfoxide reductase is 7.2 even in the absence of substr

86 methionine residues performed by methionine sulfoxide reductase is important for the gastric pathoge

87 Biotin sulfoxide reductase is not reduced by biotin or the nonp

88 The results indicate that biotin sulfoxide reductase is thermodynamically tuned to cataly

89 cepted, primarily from studies on methionine sulfoxide reductase (Msr) A, that the biological reducin

90 The methionine sulfoxide reductase (MSR) enzyme converts MetSO back to

91 Methionine sulfoxide reductase (MSR) enzyme converts MetSO back to

92 The role of methionine sulfoxide reductase (Msr), a methionine repair enzyme, i

93 phaS are excellent substrates for methionine sulfoxide reductase (Msr), thereby providing an efficien

94 de can be repaired back to Met by methionine sulfoxide reductase (Msr).

95 the reducing requirement for the methionine sulfoxide reductases (Msr), we have shown that thioredox

96 e sulfoxide (MetO) is mediated by methionine sulfoxide reductases (Msr).

97 nal changes through the action of methionine sulfoxide reductases (Msr).

98 Here we used yeast methionine sulfoxide reductases MsrA and MsrB to address this hypot

99 pair oxidized residues, including methionine sulfoxide reductases MsrA and MsrB, which reduce methion

100 reduced back to methionines by methionine-S-sulfoxide reductase (MsrA) and methionine-R-sulfoxide re

101 in proteins can be repaired by methionine-S-sulfoxide reductase (MsrA) and methionine-R-sulfoxide re

102 ulting methionine sulfoxides by methionine-S-sulfoxide reductase (MsrA) and methionine-R-sulfoxide re

103 Peptide methionine sulfoxide reductase (MsrA) repairs oxidative damage to m

104 Peptide methionine sulfoxide reductase (MsrA) reverses oxidative damage to

105 have investigated the ability of methionine sulfoxide reductase (MsrA) to maintain optimal calmoduli

106 A gene homologous to methionine sulfoxide reductase (msrA) was identified as the predict

107 The yeast peptide-methionine sulfoxide reductase (MsrA) was overexpressed in a Saccha

108 We report that peptide methionine sulfoxide reductase (MsrA), a repair enzyme, contributes

109 carboxyl terminus of the peptide-methionine sulfoxide reductase (MsrA), a repair enzyme, from Helico

110 nrelated protein known as peptide methionine sulfoxide reductase (MsrA), an antioxidant repair enzyme

111 in cytochrome c peroxidase (ccp), methionine sulfoxide reductase (msrA), or the metal-binding protein

112 lpha/beta-type SASP with peptidyl methionine sulfoxide reductase (MsrA), which can reduce methionine

113 med this compound by import and methionine-S-sulfoxide reductase (MsrA)-dependent reduction, but meth

114 that of only one protein, peptide methionine sulfoxide reductase (MsrA).

115 readily repaired by the action of methionine sulfoxide reductase (MsrA).

116 Peptide methionine sulfoxide reductase (MsrA; EC ) catalyzes the reduction

117 Peptide methionine sulfoxide reductase (MsrA; EC ) reverses the inactivatio

118 Peptide methionine sulfoxide reductase (MsrA; EC 1.8.4.6) is a ubiquitous p

119 Peptide methionine sulfoxide reductases (MsrA) from many different organism

120 S) elements, one of which was a methionine-R-sulfoxide reductase (MsrB) homolog from Metridium senile

121 -sulfoxide reductase (MsrA) and methionine-R-sulfoxide reductase (MsrB).

122 -sulfoxide reductase (MsrA) and methionine-R-sulfoxide reductase (MsrB).

123 -sulfoxide reductase (MsrA) and methionine-R-sulfoxide reductase (MsrB).

124 Methionine sulfoxide reductases (Msrs) are oxidoreductases that cat

125 reversible through the action of methionine sulfoxide reductases (MSRs), which play key roles in lif

126 thionine residues is catalyzed by methionine sulfoxide reductases (Msrs).

127 zed by a family of enzymes called methionine sulfoxide reductases (MSRs).

128 a model, we show that of the two methionine sulfoxide reductases (MXR1, MXR2), deletion of mitochond

129 In contrast, CshA- and methionine sulfoxide reductase-negative (MsrA-) strains neither adh

130 he ycbX- and yiiM-dependent pathways, biotin sulfoxide reductase plays also a role in the detoxificat

131 The enzyme peptide Met sulfoxide reductase (PMSR) catalyzes the reduction of Me

132 Peptide methionine sulfoxide reductase (PMSR) is a ubiquitous enzyme that r

133 ants and a mutant lacking peptide methionine sulfoxide reductase (pmsr2-1) showed increased protein o

134 1 cells expressing a yeast free methionine-R-sulfoxide reductase proliferated in the presence of eith

135 y evolved Sec-containing forms of methionine sulfoxide reductases reflect catalytic advantages provid

136 icroM for reduced methyl viologen and biotin sulfoxide reductase, respectively.

137 Reversing oxidation with methionine sulfoxide reductase restored HDL's ability to activate L

138 g the structures for R. sphaeroides dimethyl sulfoxide reductase, Rhodobacter capsulatus dimethyl sul

139 e intracellular and extracellular methionine sulfoxide reductases (SpMsrAB1 and SpMsrAB2, respectivel

140 MsrPQ is a newly identified methionine sulfoxide reductase system found in bacteria, which appe

141 n-Benson-Bassham, dinitrogenase and dimethyl sulfoxide reductase systems, were probed in strains grow

142 (2-Ad = 2-adamantyl, DMSOR = dimethyl sulfoxide reductase, TMAOR = trimethylamine N-oxide redu

143 UGA) of Mycoplasma pneumoniae and methionine sulfoxide reductase (two UGAs) of Mycoplasma genitalium.

144 eins involving the enzyme peptide methionine sulfoxide reductase type A (MSRA) is postulated to serve

145 man spectra previously reported for dimethyl sulfoxide reductase, vibrational modes associated with a

146 Biotin sulfoxide reductase was also capable of reducing nicotin

147 (MsrA)-dependent reduction, but methionine-R-sulfoxide reductases were not involved in this process,

148 Methionine sulfoxide reductase, which reduces methionine sulfoxide

149 Most cells contain methionine sulfoxide reductases, which catalyze a thioredoxin-depen

150 Reduction back to methionine by methionine sulfoxide reductases would allow the antioxidant system