ライフサイエンスコーパス: supergene

1 enotype is controlled by a single Mendelian 'supergene'.

2 pecies tree is estimated from the resultant 'supergenes'.

3 e, function and evolution of this archetypal supergene.

4 nario for the evolution of recombination and supergenes.

5 and establish co-adapted gene complexes, or supergenes.

6 that groups of tightly linked genes (i.e., "supergenes" [1, 2]) facilitate adaptation in suites of t

7 address the critical issue of what a mimicry supergene actually is at a functional level.

8 and phylogenomic data to show that alternate supergene alleles are highly divergent at over 1,000 gen

9 ortance, little is known about how alternate supergene alleles arise and become differentiated, nor t

10 election for reduced recombination between a supergene and a nearby locus providing additional benefi

11 es considered separately or combined into a 'supergene') and the way gene-specific rate models are ap

12 ctional role of multiple elements within the supergene architecture has been demonstrated, conclusive

13 Supergenes are clusters of physically linked, co-evolvin

14 is is in contrast to the long-held view that supergenes are likely to be controlled by a tightly link

15 Here we reveal the S locus supergene as a tightly linked cluster of thrum-specific

16 Supergene chalcocite enrichment during weathering is an

17 ity of the evolutionary development of large supergene complexes that confer a selective advantage to

18 f the evolution of sex chromosomes and other supergene complexes.

19 Despite recent criticism, we argue that the supergene concept remains relevant and is more testable

20 to satellites and faeders is determined by a supergene consisting of divergent alternative, dominant

21 The locus is an example of a 'supergene' controlling multiple complex phenotypes.

22 g Batesian mimicry, a multi-gene complex or 'supergene' controls the multiple differences between mim

23 activity may thus be a fundamental factor in supergene enrichment of copper deposits.

24 ay reflect the functional diversification of supergene families consistent with major differences in

25 veals that a considerable expansion of these supergene families has occurred in the mosquito.

26 This process is facilitated by several supergene families that catalyze oxidative metabolism as

27 coproteins are members of the immunoglobulin supergene family and are related structurally to carcino

28 ithelial adhesion molecule of immunoglobulin supergene family and has been implicated in the growth s

29 uzi CRP and its relationship to the T. cruzi supergene family comprising active trans-sialidase (TS)

30 mbers of the glutathione S-transferase (GST) supergene family is associated with altered NMSC risk in

31 that the function of many members of the Ig-supergene family is dependent on interactions with cytop

32 The protein tyrosine kinase (PTK) supergene family is the key mediator in cellular signali

33 of the desmoglein subfamily of the cadherin supergene family of cell adhesion molecules.

34 Apobec-1 is a member of a supergene family of cytidine deaminases, with several ho

35 ma and PPARalpha, comprise a subclass of the supergene family of nuclear receptors.

36 ells express one or more members of the Ly-6 supergene family of small glycosylphosphatidylinositol-l

37 osophila mef2 gene, a member of the MADS box supergene family of transcription factors, is critical f

38 cytochromes P450, the dominant froms of this supergene family that catalyze the oxidation of numerous

39 CD200R is a member of the Ig supergene family that is primarily expressed on myeloid

40 member of the carcinoembryonic antigen (CEA) supergene family, indicate that it is a multifunctional

41 protein belonging to the carcinoembryonic Ag supergene family.

42 in (or spectrin II), members of the spectrin supergene family.

43 146, is a novel member of the immunoglobulin supergene family.

44 Recently, the molecular basis for several supergenes has been resolved.

45 investigating the evolutionary history of a supergene in white-throated sparrows, Zonotrichia albico

46 to lead to the discovery of many additional supergenes in a broad range of organisms and reveal simi

47 influence the phenotypic effects of presumed supergenes in hybrids.

48 been made, suggesting an important role for supergenes in the evolution of divergent behavioral phen

49 within a number of putative differentiated "supergenes" in the rice genome, which may reflect crypti

50 but application at molecular levels (e.g., 'supergenes' in genetics) is more recent, with a consensu

51 ctional selection, whereas the single-locus (supergene) inheritance controlling polymorphism in H. nu

52 Furthermore, molecular evolution of the supergene is dominated not by adaptive protein evolution

53 the excess of heterozygote genotypes at the supergene locus controlling wing-pattern variation in na

54 gation of adaptive variation within species, supergenes may facilitate the spread of complex phenotyp

55 Some supergenes may span entire chromosomes, because selectio

56 butterflies from a recent radiation in which supergene mimicry has been isolated to the gene doublese

57 show that a single gene, doublesex, controls supergene mimicry in Papilio polytes.

58 Supergene mimicry is a striking phenomenon but we know l

59 rk has explored the evolutionary dynamics of supergene mimicry, there are almost no empirical data th

60 cing an ore assemblage previously unknown in supergene mineralizing environments.

61 lting from recent sub-surface replacement of supergene oxyhydroxides by carbonate and sulphide minera

62 lleles at a balanced >100-Mb inversion-based supergene, providing a unique system for studying gene-b

63 These 'supergenes' segregate as stable polymorphisms within or

64 rom different hypotheses for the identity of supergenes, showing that a single gene can switch the en

65 he origin and possible fate of a fascinating supergene that determines the coloration and mating beha

66 such polymorphisms led to the concept of the supergene, where alternative phenotypes in a balanced po