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2 Mutator (Mu) transposon lines identified the supernumerary aleurone layers 1-1 (sal1-1) mutant line c
5 tholog in Caenorhabditis elegans, results in supernumerary apoptotic corpses, whereas its overexpress
10 al nervous systems, including the removal of supernumerary axonal inputs from neuromuscular junctions
12 Knockdown of Hap1 promotes specification of supernumerary axons in primary hippocampal neurons and p
15 esult from reciprocal interchanges between a supernumerary B chromosome and an arm of an essential A
23 excess Buc disrupts polarity and results in supernumerary Balbiani bodies in a 3'UTR-dependent manne
24 the developing avian neural tube resulted in supernumerary blood vessel ingression points and disrupt
25 non-heparin-binding VEGF121 did not produce supernumerary blood vessel ingression points, although t
26 One mutation, which caused production of supernumerary border cells, was found to disrupt the cos
31 ve phenotype and promoted the development of supernumerary carpels under water-stress conditions.
32 tion, the double-deficient embryos developed supernumerary cartilage elements in the zeugopod, reveal
33 erning, ectopic expression of SHR results in supernumerary cell divisions and abnormal cell specifica
34 lineage; loss of bazooka function results in supernumerary cell divisions and apoptotic cell death.
35 last cells undergo extra divisions, creating supernumerary cells that can differentiate and function
36 ptosis, which remodels tissue by eliminating supernumerary cells, also contributes forces to a tissue
37 biquitination and promotes the generation of supernumerary centriolar foci, whereas ablation of USP33
38 t occur only once per cell cycle; otherwise, supernumerary centrioles can induce aneuploidy and tumor
41 y long centrioles but also produced atypical supernumerary centrioles that grew from these long centr
43 y cells from Cep290-deficient mice exhibited supernumerary centrioles, decreased replication fork vel
44 ocious degradation of cyclin B by the APC/C, supernumerary centrioles, lagging chromosomes, and aneup
47 Elevated Plk4 in mouse fibroblasts produced supernumerary centrosomes and enhanced the expected mito
48 xed tissue sections revealed the presence of supernumerary centrosomes and lagging chromosomes among
50 trically dividing neuroblasts, which display supernumerary centrosomes and spindle abnormalities duri
51 d to the appearance of tetraploid cells with supernumerary centrosomes and, ultimately, to cell death
55 lts indicate that oligoclonal aneuploidy and supernumerary centrosomes are early hallmarks of Bax-ind
56 We conclude that, independent of p53 status, supernumerary centrosomes are not sufficient to drive tu
58 of aneuploid cancer cells, we tested whether supernumerary centrosomes are sufficient to drive tumor
60 at disruption of interphase cell behavior by supernumerary centrosomes contributes to pathology indep
62 echanistically, tumor endothelial cells with supernumerary centrosomes had less centrosome-localized
63 n of this synchrony causes defects including supernumerary centrosomes in cancer and perturbed ciliar
64 r mitosis where a131's ability to de-cluster supernumerary centrosomes in cancer cells eliminates Ras
66 ice, Bax expression increased aneuploidy and supernumerary centrosomes in p53-/- mice but not in p53+
69 cal and ultrastructural examination of these supernumerary centrosomes revealed that inactivation of
71 wn that griseofulvin forces tumor cells with supernumerary centrosomes to undergo multipolar mitoses
72 Furthermore, the ability of HBV to induce supernumerary centrosomes was dependent on the presence
76 ent of aneuploidy followed the prevalence of supernumerary centrosomes within distinct cell populatio
77 many solid tumors have been found to contain supernumerary centrosomes, a condition known as centroso
78 riggered dysplastic mitoses, accumulation of supernumerary centrosomes, abnormalities of the mitotic
79 SV40 ST expression and show that ST induces supernumerary centrosomes, an activity we also demonstra
80 bnormal mitotic spindle structure, including supernumerary centrosomes, and changes in POC1A were acc
82 e of proliferation, to suppress formation of supernumerary centrosomes, and to maintain genomic integ
84 rference produced multinucleated cells, with supernumerary centrosomes, multipolar spindles and laggi
94 ple CFs; an activity-dependent regression of supernumerary CFs ultimately yields a single innervation
95 n cells with cytoskeletal protein mutations, supernumerary ChR1 patches remained adjacent to acetylat
96 [PSI (+)]-containing strains could lead to a supernumerary chromosome due to the presence of the ade1
97 eved by fertilization with sperm bearing the supernumerary chromosome paternal sex ratio (PSR), which
98 he poorly characterized mechanisms of PSR, a supernumerary chromosome that induces paternal autosome
101 significance of the EBR1 family expansion on supernumerary chromosomes and whether EBR1 paralogues ar
102 that pathogenic forms of this fungus harbour supernumerary chromosomes with a wide variety of genes,
103 rate a remarkable excess of centrioles, with supernumerary cilia but deficient Hedgehog signaling.
105 maging to observe competitive elimination of supernumerary climbing fibers (CFs) in the cerebellum of
111 mutants but also displays distorted embryos, supernumerary cotyledons, multiple shoot meristems, and
113 ia eutropha and Hydrogenovibrio marinus, two supernumerary Cys residues coordinate the proximal [FeS]
114 nitor cells, and when overexpressed leads to supernumerary DA neurons in the forebrain of zebrafish.
115 e genomic intervals and that the majority of supernumerary-der(22) offspring result from a 3:1 meiosi
116 22) in both of the offspring with unbalanced supernumerary-der(22) syndrome, suggesting that the brea
117 s two additional, independent cases with the supernumerary-der(22) syndrome, were analyzed to compare
119 ve robust digits, but a very small, possibly supernumerary digit preserved on the manus suggests the
121 se Posterior Limb Bud-4 cell line can induce supernumerary digits, including digits with posterior ph
123 nction demonstrated spontaneous activity and supernumerary discharges with increased transmitter rele
124 onic/early larval pigment pattern forms, but supernumerary early larval melanophores persist in ectop
125 ator of melanophore development, resulted in supernumerary ectopic iridophores while loss of foxd3, a
128 mpanying loss of individual fitness) by this supernumerary fertilization product was dependent upon c
129 r cells prior to fusion, causes formation of supernumerary fibers, suggesting that cells in the myobl
130 that these cells are responsible for seeding supernumerary fibers, when DVM FCs are eliminated prior
132 ence and floral meristems, the production of supernumerary flowers and floral organs, and a delay in
134 yonic fibroblasts, the tumor cells contained supernumerary functional centrosomes with intact centrio
135 n(S270A), which facilitates the formation of supernumerary GABAergic synapses in vitro, favors dendri
136 emagglutinin (HA) inserted as an additional, supernumerary gene between the HPIV3 P and M genes.
137 erted individually or in homologous pairs as supernumerary genes in the promoter proximal position of
138 creased expression of one or more of the 231 supernumerary genes on the extra copy of chromosome 21.
140 mesial lesion who sporadically experiences a supernumerary 'ghost' left arm that occupies the previou
141 d the formation of small, heterogeneous, and supernumerary glomeruli that failed to undergo neural pr
144 n of Corti is severely disrupted, exhibiting supernumerary hair cells at the apex, showing mirror-ima
145 nalling [mindbomb mutant or Su(H) morphant], supernumerary hair cells develop and otolith precursor p
146 2 (Jag2) gene, which encodes a Notch ligand, supernumerary hair cells differentiate in the cochlea of
148 geted deletion of Hes1 leads to formation of supernumerary hair cells in the cochlea and utricle of t
149 lacking the Notch ligand JAG2 differentiate supernumerary hair cells in the cochlea, consistent with
150 ons of both Jag2 and Lfng, the generation of supernumerary hair cells in the inner hair cell row is s
152 the inner hair cell row is suppressed, while supernumerary hair cells in the outer hair cell rows are
153 ological defects of the organ of Corti, with supernumerary hair cells, as also reported for Hes5 null
157 ce displayed variable hypodontia, occasional supernumerary incisors and molars, as well as crown and
161 each of which contains a neocentromere on a supernumerary inversion duplication of a portion of huma
162 Often these abnormalities take the form of a supernumerary inverted duplicated chromosome 15, more pr
163 n caused all cells of the placode to form as supernumerary IPC NBs, indicating that the placode is in
164 uplications, interstitial triplications, and supernumerary isodicentric marker chromosomes, as well a
165 of smaller caliber) and that the presence of supernumerary large caliber Mauthner axons can profoundl
167 ive MMP3 in mouse mammary epithelia triggers supernumerary lateral branching and, eventually, tumors.
170 ry and sufficient to induce the formation of supernumerary limbs from blastemal tissue in axolotl sal
171 Here we describe a new gene, slimb (for supernumerary limbs), which negatively regulates both of
172 oss of Fgf20 delays formation of Eda-induced supernumerary mammary buds and normalizes the embryonic
174 , X and Y between spermatozoa with the small supernumerary marker chromosome (sSMC; sSMC(+)) and sper
175 associated with a distinct phenotype, and a supernumerary marker chromosome, +der(8)(8p23.1pter), wh
182 A-insensitive mutant led to the formation of supernumerary megaspore mother cells, suggesting that TE
183 positive (microtubule-associated protein 1B) supernumerary microtubule loops is elevated in dfmr1 nul
184 tissues is the ability to induce suicide of supernumerary, misplaced or damaged cells with high spec
187 Dll dsRNA-injected larvae underwent numerous supernumerary molts, which could be terminated with inje
188 f fish or fly Nkx6 is sufficient to generate supernumerary motoneurons in both zebrafish and flies.
189 For this reason we examined the timing of supernumerary nerve terminal elimination at synapses in
190 erved a dramatic delay in the elimination of supernumerary nerve terminals from synapses in the levat
191 extensive neuronal sprouting, including many supernumerary neurites and terminal branches as well as,
192 ing Arm activity in immature INPs suppresses supernumerary neuroblast formation in brat mutant brains
193 ecification of INP identity and enhances the supernumerary neuroblast mutant phenotype in brat mutant
194 n mitotic neuroblasts and suppression of the supernumerary neuroblast phenotype induced by increased
196 with ectopic basal aPKC is the appearance of supernumerary neuroblasts in twins mutant brains or twin
197 ducing Arm activity also strongly suppresses supernumerary neuroblasts induced by overexpression of k
199 ensive hyperplasia of hematopoietic tissues, supernumerary neuronal cells, and head involution failur
201 These results may reflect the presence of supernumerary neurons beneath the cortical plate that co
210 he potential for interspecific movement of a supernumerary or B chromosome and its subsequent stabili
212 to various developmental defects, including supernumerary or missing teeth, enamel and dentin hypopl
213 t resulted in enlarged meristems and organs, supernumerary organs in floral whorls, arrested developm
217 ncomplete resident hemocyte pattern, whereas supernumerary peripheral neurons induced by ectopic expr
218 ly, overactivation of these molecules causes supernumerary PGCs, their premature transit through the
219 regeneration, including the development of a supernumerary pharynx (the feeding organ of the animal)
222 misexpression of Wnt8 causes development of supernumerary placodes/vesicles, but this reflects poste
226 pocampal), an enlarged posterior commissure, supernumerary pontine cholinergic and noradrenergic cell
227 ng with an enlarged posterior commissure and supernumerary pontine cholinergic and noradrenergic neur
228 n a wild-type limb bud causes formation of a supernumerary posterior digit (postaxial polydactyly), a
230 contrast, receptor hyperactivation generates supernumerary progenitors, as well as the duplication of
231 e duplications most often take the form of a supernumerary pseudodicentric derivative chromosome 15 [
232 xperimentally reduced delta signalling, have supernumerary Rohon-Beard neurons, reduced trunk-level e
233 of Hensen's node can induce the formation of supernumerary rudimentary limbs from the non-limb-formin
234 No evidence of transdifferentiation of these supernumerary SCs into HCs was observed in the p130(-/-)
235 h cul-1 and lin-23 mutants the phenotypes of supernumerary seam cell divisions, defective alae format
237 t of nested inversions and at least one long supernumerary segment at the end of the chromosome.
238 advance cancer measurably, whereas a single supernumerary segment encompassing all four genes succes
241 Since the induced patterned ectoderm and supernumerary skeletal elements are derived from the hos
242 s unmasked multiple abnormalities, including supernumerary spermathecae, degenerative ovaries, and se
243 anscription factor results in development of supernumerary sporangia attached to a single seta, sugge
248 o the structural and functional roles of the supernumerary subunits and reveal new information on the
249 cantly extend knowledge of how the mammalian supernumerary subunits are arranged around the core enzy
250 al stalk and that the N termini of the other supernumerary subunits are on the same side of the membr
251 d core subunits and 31 mitochondria-specific supernumerary subunits are resolved within the L-shaped
252 talytic and peripheral stalk domains and the supernumerary subunits e, f, and g, but lacking membrane
254 ture provides insights into the roles of the supernumerary subunits in regulation, assembly and homeo
257 UFB11 encodes one of 30 poorly characterized supernumerary subunits of NADH:ubiquinone oxidoreductase
258 he membrane domain, subunit a and associated supernumerary subunits, kept in contact with the rotor t
259 d modelled all 45 subunits, including the 31 supernumerary subunits, to provide the entire structure
268 criptive, gene tree-based variants featuring supernumerary symbionts: prokaryotic partners distinct f
272 factor odd-skipped related-2 (Osr2) develop supernumerary teeth lingual to their molars because of e
275 ooth abnormalities, including hypodontia and supernumerary teeth, aberrant crown and root morphologie
276 ner's syndrome, a condition characterized by supernumerary teeth, mandibular osteomas, and other mala
277 ar teeth with extra cusps, and in some cases supernumerary teeth, the opposite of the mutant phenotyp
282 h development but was sufficient to suppress supernumerary tooth formation in the Osr2(-/-) mutant mi
283 n embryonic mouse oral epithelium results in supernumerary tooth formation, but the underlying mechan
286 exhibited formation and subsequent arrest of supernumerary tooth germs that correlated with downregul
287 Moreover, in contrast to complete lack of supernumerary tooth initiation in Msx1(-/-)Osr2(-/-) mic
288 rs and 60 transmembrane helices, identify 18 supernumerary transmembrane helices, and assign and mode
289 inations of overlapping fragments containing supernumerary transmembrane segments also led to formati
290 abnormalities, most strikingly production of supernumerary trichomes on cotyledons, leaves and stems.
292 and multicystic kidneys that were caused by supernumerary ureteric buds that fail to separate from t
293 in axon guidance and cell migration, develop supernumerary ureteric buds that remain inappropriately
295 1, there are fewer secondary motoneurons and supernumerary ventral interneurons, suggesting Nkx6.1 pr
297 eres 2-7, which results in the production of supernumerary viscerosensory and somatosensory neurons o
299 own to have mild effects because most of the supernumerary X genes are inactivated and not affected b
300 Allometric analysis of SCA reveals that supernumerary X- and Y-chromosomes both cause disproport
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