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1 teinase K studies demonstrate that BbHtrA is surface exposed.
2 embrane, with its C-terminal variable region surface exposed.
3 ce; a few lipoproteins have been shown to be surface exposed.
4 ciated with spirochete outer membrane and is surface exposed.
5 accessibility and opsonophagocytosis assays, surface exposed.
6 parts of helices two and three are primarily surface-exposed.
7 in the absence of BamE, BamD indeed becomes surface-exposed.
8 N-terminal deletion mutants were selectively surface-exposed.
9 n, cleaves PCSK9 at Arg(218)-Gln(219) in the surface-exposed "218 loop." This cleaved form circulates
10 self-assembling peptoid nanosheet containing surface-exposed Abeta42-recognizing loops is constructed
11 lysine residues of their collagen stalks and surface exposed acidic residues located in CR1 CCP24 and
13 ptors of H. pylori and show that HopQ is the surface-exposed adhesin that specifically binds human CE
15 ize various tissues requires the presence of surface-exposed adhesins that have been difficult to ide
17 itioned by the amino acid composition of two surface-exposed alpha-helices of the SSU: higher plant-l
18 bacterial two-hybrid analysis to identify a surface-exposed alpha-helix in the C-terminal mannosyltr
19 length distribution depend primarily on the surface-exposed amino acids in specific regions rather t
21 nontypeable Haemophilus influenzae (NTHi) is surface exposed and a leading vaccine candidate for prev
23 zinc finger and phosphorylation interface as surface exposed and available for subsequent reactions.
25 results demonstrate that OmpA1 and OmpA2 are surface exposed and could potentially bind to different
26 a dual orientation, existing infrequently as surface exposed and predominantly as internally oriented
27 ious studies have suggested that FTT0831c is surface exposed and required for virulence of Francisell
30 escence microscopy suggests that BoMan26B is surface-exposed and associated with the outer membrane,
31 ion involved complex interactions among both surface-exposed and buried capsid mutations that togethe
36 e.g. Bordetella pertussis) strains produce a surface-exposed and secreted protein called filamentous
37 niques demonstrated that OmpA1 and OmpA2 are surface exposed, and are not masked by the polysaccharid
38 We show that BBA57, an outer membrane and surface-exposed antigen, is a major trigger of murine Ly
47 rbomycin is bound in two distinct buried and surface-exposed binding pockets, mediated by specific in
48 7 had sequence features of lipoproteins, was surface exposed by the criteria of in situ protease susc
49 istry of numerous probe molecules on various surfaces exposed by three very important metal oxides (Z
50 Rv0888 is an unusual membrane protein with a surface-exposed C-terminal sphingomyelinase domain and a
51 of Gram-positive bacteria contains abundant surface-exposed carbohydrate molecules that are highly c
54 to utilize a large family of highly related surface-exposed cell wall proteins, the lectin-like epit
60 ssa) introduces carboxyl groups primarily in surface-exposed crystalline areas of the cellulosic subs
62 ation photochemically within beta2, a single surface-exposed cysteine of the beta2 subunit of Escheri
64 engineered 23 FVIII variants with introduced surface-exposed cysteines to which a polyethylene glycol
65 p53 in vitro via selective alkylation of two surface-exposed cysteines without compromising its DNA b
66 h 1 kD and 10 kD) were chemically coupled to surface exposed Cyt c lysine (Lys) residues using succin
67 e domain bound to a metal ion, we identify a surface-exposed di-histidine motif in MamO that contribu
70 The crystal structure of the C-terminal, surface-exposed domain of TraM was determined to 2.5 A r
71 mutations that alter the positively charged surface-exposed domain, we show that RcsF monitors later
72 initively; we argue that these molecules are surface-exposed (during apoptotic cell death), ubiquitou
75 yeast Candida glabrata harbors more than 20 surface-exposed, epithelial adhesins (Epas) for host cel
76 onal manner by forming a spatially clustered surface-exposed epitope conferring optimal IgE-binding c
80 bacteria use the toxic C-terminus of a large surface-exposed exoprotein to inhibit the growth of susc
81 es, in that residues occupying the predicted surface-exposed face of CfaB and related class 5 pilins
82 argeting dopaminergic neurons, reaction with surface-exposed FLAG epitope-tagged D2R, and blocking of
84 otein-protein interface of intracellular and surface-exposed fusion complexes and investigated the ef
89 provide new insights into the repertoire of surface-exposed H. pylori proteins that may mediate bact
93 of FVII, the FVII GLA domain sits within the surface-exposed hexon trimer depression in a different o
94 ed for other AAVs but uniquely differ in the surface-exposed HI loop between betaH and betaI of the c
97 ents, and recent studies have shown that the surface-exposed HtaA protein binds both hemin and Hb and
98 es inside-out conformations where previously surface-exposed hydrophilic side chains get buried along
99 st that the amino acids making up the large, surface-exposed hydrophobic cap in the crystal structure
100 o-terminal beta-hairpin at the distal site-a surface-exposed hydrophobic crevice 17 A away from the a
101 l side of this interface likewise involves a surface-exposed hydrophobic helix, namely, the D-helix o
103 the N-Cap amphipathic helix interacts with a surface-exposed hydrophobic patch on the core of the PAS
106 dy, we made site-directed mutagenesis on the surface-exposed hydrophobic residues of pvLAAD INS, and
107 eonine-rich region that provides an array of surface-exposed hydroxyl groups that bind to polyQ pepti
109 ch, we show here that the LTA polymer is not surface exposed in S. aureus, as it can only be detected
110 p123, a site buried in the Nef:SH3 dimer but surface exposed in the Nef:SH3-SH2 complex), showed a Hc
112 sine residues, which are buried in FVIII and surface-exposed in dissociated activated FVIII (dis-FVII
113 (C)-like domains of native TprC and TprI are surface-exposed in T. pallidum, whereas their MOSP(N)-li
114 h prokaryotic Argonautes, KpAGO has numerous surface-exposed insertion segments, with a cluster of co
116 Because the alginate exopolysaccharide is surface-exposed, levels of SP-A may be crucial to modula
118 cci bind fH via fH binding protein (fHbp), a surface-exposed lipoprotein that is subdivided into thre
120 orferi outer membrane (OM) contains numerous surface-exposed lipoproteins but a relatively low densit
121 however, now suggest that the prevalence of surface-exposed lipoproteins has been underestimated.
122 Interestingly, a decrease in the levels of surface-exposed lipoproteins was also observed in the mu
123 There are few examples of Gram-negative, surface-exposed lipoproteins, and VolA is unique, as it
126 successfully tested the contribution of each surface-exposed loop in the trypsin fold alone and the c
129 meric recombinant PorB loop mutants in which surface-exposed loop residues have been switched between
131 trypsin-like serine proteases have flexible surface-exposed loops and are known to adopt higher and
132 hgbA by deletion of each of the 11 putative surface-exposed loops and expressed each of the mutant p
133 onses that are directed against six variable surface-exposed loops that differ in sequence depending
134 titutions are located in the vicinity of the surface-exposed loops that engage sigma(54) during the A
135 ory domains were inserted into nonconserved, surface-exposed loops that were tight and identified com
139 esis, which identifies two highly conserved, surface-exposed lysine residues in this region of the tr
140 iquibodies reliably transferred ubiquitin to surface exposed lysines on target proteins and even cata
141 clusion, the study demonstrates that the six surface-exposed lysines in protein G are not involved in
144 In this study we demonstrate that SpyA is a surface-exposed membrane protein which is anchored to th
146 on of cells that expressed CD133, an unusual surface-exposed membrane-spanning glycoprotein associate
148 the canonical vancomycin binding site, these surface-exposed molecules confer increased vancomycin-re
149 e (OMPeome), which we postulate includes the surface-exposed molecules detected by our enhanced gel m
150 eveals a high degree of allelic variation in surface-exposed molecules, including adhesins that promo
153 hat the myristoyl group lies in a relatively surface exposed "myristoyl nest." We propose that this s
155 t cell wall-anchored C terminus, whereas the surface-exposed N terminus is highly variable, a feature
157 ecombinant mutants of FI carrying additional surface-exposed N-glycosylation sites that were expected
158 at Lmp1 is an integral membrane protein with surface-exposed N-terminal, middle, and C-terminal regio
159 ctivity of native enzyme, elimination of the surface-exposed negative charge at Asp(50) results in si
160 molecular surface, with the vast majority of surface-exposed, nonconserved residues being clustered t
162 oportion to the product of the amount of DNA surface exposed on melting and the amount of PEG surface
163 ite consists of a patch of residues that are surface-exposed on the face of the extracellular domain
165 jugates conjugated through either engineered surface-exposed or reduced interchain disulfide bond cys
167 Proteins that met multiple criteria for surface-exposed outer membrane localization included kno
172 y imaging confirmed that antibodies targeted surface-exposed P6 of intact NTHi cells and not internal
173 sion and specifically illuminate the fate of surface-exposed parasite proteins during and immediately
174 ng signal peptide followed by an N-terminal, surface-exposed passenger domain and a C-terminal domain
175 of CagA sequences identified four conserved surface-exposed patches (CSP1-4), which represent putati
176 inates binding to the 70S ribosome via three surface-exposed patches of basic residues that we propos
179 he enzyme that starts at a highly conserved, surface-exposed phenylalanine and is relayed to the acti
180 of copper nitrite reductase by mutation of a surface-exposed phenylalanine residue (Phe306), located
183 between NrdH-redoxin and TrxR, where the two surface-exposed phenylalanines of TrxR perfectly fit int
184 is of apoptotic cells by bridging cells with surface exposed phosphatidylserine (PS) to macrophage re
185 haracterized with respect to the presence of surface-exposed pili, DNA uptake, and natural transforma
186 nds as an extended conformation in a narrow, surface-exposed pocket formed only in the DNA-bound stat
193 Da dihydrolipoamide dehydrogenase (Lpd) as a surface-exposed protein of P. aeruginosa that binds the
194 n of virulence by surfaces also requires the surface-exposed protein PilY1, which has a domain homolo
195 e concluded that S. suis BgaC is an atypical surface-exposed protein without the involvement of bacte
198 ps was variable and large at 3 loci encoding surface-exposed proteins (0.4 < K(S) < 1.3, where K(S) i
202 ence protein (Eap) and autolysin (Atl), both surface-exposed proteins containing repeating structures
204 a quantitative proteomic comparison of cell surface-exposed proteins in human cancer cells that were
207 ltiple mechanisms to alter the expression of surface-exposed proteins through the processes of phase
210 pe independent and mediated by the bacterial surface-exposed proteins, as pretreatment of pneumococci
211 dation of particular, but not all, bacterial surface-exposed proteins, including TRP120, which is ass
212 n this study, the selective biotinylation of surface-exposed proteins, streptavidin affinity purifica
214 s spectrometry were used to characterize the surface-exposed proteome of M. avium subsp. hominissuis.
216 rface, indicating that they are likely to be surface exposed rather than buried as in structures of A
217 n as cell attachment factors by binding to a surface-exposed region in the protruding (P) domain of t
218 volutionarily linked amino acids appear on a surface-exposed region of one subunit while in a noncata
219 icted secondary structure of the C-terminal, surface-exposed region of OprF has high structural ident
220 of DBLbeta3_D4, these cluster to a defined, surface-exposed region on the convex surface of DBLbeta3
221 related protein, interleukin (IL)-22, with a surface-exposed region that is structurally homologous i
222 f transient interactions are correlated with surface exposed regions that exhibit a high propensity t
223 strain-specific sequence variability within surface-exposed regions (loops) putatively involved in T
224 sed to identify candidate ISDs residing near surface-exposed regions in Arabidopsis thaliana crucifer
225 dings reported here underscore the fact that surface-exposed regions of Lmp1 could potentially serve
226 odel-guided mutagenesis: three conserved and surface-exposed regions of modeled YscO were targeted fo
227 lutionary trace analysis to pinpoint several surface-exposed regions of potential functional importan
228 rential immune activation could be mapped to surface-exposed regions of the capsid, such as hypervari
229 ISDs are adjacent to or within hydrophilic, surface-exposed regions that serve to present them on th
230 re, we show that amino acid variation within surface-exposed regions within outer membrane P5 affecte
233 roteins were generated, each having a single surface-exposed residue mutated to alanine or a conserva
234 a conserved glycine at amino acid VP1-145, a surface-exposed residue that maps to the 5-fold vertex a
235 used by a Glu-26-Lys mutation that targets a surface-exposed residue unlikely to affect the intramole
237 ified tyrosine 280 in combination with other surface-exposed residues (the YNND epitope) as critical
242 nder positive selection were predicted to be surface-exposed residues in the P2 domain, in contrast t
244 h mild EI mutations were found to affect the surface-exposed residues of the K10 alpha helix coiled-c
245 explain the presence of conserved patches of surface-exposed residues on gp33, and provides a structu
247 Blo t 1, as well as of sequence identity of surface-exposed residues, suggests limited cross-reactiv
249 ve considerably increased in size, forming a surface-exposed ribosomal RNA (rRNA) shell of unknown fu
250 oach, in which peptides representing various surface-exposed segments of a protein are initially prob
255 removal of all tail residues predicted to be surface-exposed significantly restores RNP bioactivity.
257 cts at the active site (Trp87) and a remote, surface-exposed site (Trp167), time-dependent Stokes shi
259 ved ECM is controlled by a novel, conserved, surface-exposed site on the thrombospondin L-type lectin
262 es or protein-protein/ligand interactions at surface-exposed sites of membrane protein complexes in w
263 ssDNA-binding sites, and we speculate that a surface-exposed ssDNA-specific site is involved in catal
270 rrent density radially inward on the silicon surface exposed to Triton((R)) X-100 containing HF based
271 ly due to the reduced hydrophobic pyrimidine surface exposed to water after anion aggregation, and th
272 oosmotic flow (EOF, i.e. the water flow over surfaces exposed to a weak direct current (DC) electric
274 cuticles and attracted water to hydrophobic surfaces exposed to high relative humidity due to its hy
275 the different plants and the normalizing the surfaces exposed to nanoparticles, the RHIZOtest demonst
276 formation of FH-sialic acid-C3b complexes on surfaces exposed to plasma is essential for preventing c
278 ems: across 31 trees in a Panama rainforest, surfaces exposed to sun were 8 degrees C warmer and vari
279 n was significantly greater on all patterned surfaces exposed to TGFbeta (P < 0.002), whereas cells g
280 xtent of heterogeneous nucleation at mineral surfaces exposed to the fluids in porous reservoirs.
281 m with pathologic bacteria can cover implant surfaces exposed to the oral cavity, for example, due to
284 model, electrostatic interactions as well as surface-exposed Tyr residues bind WaaG to the membrane.
285 ping experiments, a transient radical on the surface-exposed Tyr-337 was identified as the oxidation
286 of the viral capsid proteins where specific surface-exposed tyrosine (Y) and threonine (T) residues
288 Recent evidence suggests that the putative surface-exposed variable antigen TprK plays an important
292 support the idea that the lipase activity of surface-exposed VolA likely contributes to the success o
293 three key binding determinants located in a surface-exposed 'W56 loop' of PspF, which form a tightly
295 ree-form Lpp spans the outer membrane and is surface-exposed, whereas bound-form Lpp resides in the p
296 he proteins encoded by these two operons are surface exposed, which is consistent with the presence o
298 ence (PelB-MOSP), MOSP(C) is OM-embedded and surface-exposed, while MOSP(N) resides in the periplasm.
300 cted more weakly with zinc possessing a less surface-exposed zinc-binding site, and stayed monomeric.
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