ライフサイエンスコーパス: surfactant protein B

1 ide consisting of the first 25 residues from surfactant protein B.

2 ng at cellular sites consistent with that of surfactant protein B.

3 solated preparations or to altered levels of surfactant protein B.

4 ct with TTF-1 and regulate the expression of surfactant protein B, a protein required for lung functi

5 21-residue functional peptide mimic of lung surfactant protein B, an essential protein for lowering

6 SP-B1-25 is a shorter version of lung-surfactant protein B, an important component of lung sur

7 nduced transcriptional activity of the mouse surfactant protein B and A (Sftpb and Sftpa) promoters i

8 nment of this fragment with type II-specific surfactant protein B and C promoters shows similar conse

9 ary acute lung injury, CPAP-30 yielded lower surfactant protein-B and higher type III procollagen exp

10 hown promise as functional analogues of lung surfactant proteins B and C (SP-B and SP-C), two helical

11 nts were made for PL and DAPL alone; with 3% surfactant proteins B and C (SP-B/C); with SP-B/C and 5%

12 Surfactant proteins B and C and saturated phosphatidylch

13 factant (BC mixture = PL mixture + synthetic surfactant proteins B and C) at a dose of 100 mg alpha1-

14 ara cells, Clara cell secretory protein, and surfactant proteins B and C, without affecting airway ci

15 regions which could bind to the hydrophobic surfactant proteins B and C.

16 rfactant protein C, 95% for mucin-1, 93% for surfactant protein B, and 89% for the epithelial marker

17 recursor, pigment epithelium-derived factor, surfactant protein B, and serum amyloid A.

18 Genetic variations in the gene coding for surfactant protein B are associated with more severe lun

19 type II cell differentiation, as measured by surfactant protein B/C mRNA and protein levels.

20 Lung morphology, surfactant proteins B-D, lung tissue, alveolar phospholi

21 atory adaptation at birth include hereditary surfactant protein B deficiency, mutations in surfactant

22 n 4 of the surfactant protein B gene and the surfactant protein B gene +1580 polymorphism.

23 andem repeat polymorphism in intron 4 of the surfactant protein B gene and the surfactant protein B g

24 These reagents down-regulated surfactant protein B gene expression in respiratory epit

25 is study, the variable nuclear tandem repeat surfactant protein B gene polymorphism in intron 4 is as

26 e presence of variable nuclear tandem repeat surfactant protein B gene polymorphism was associated wi

27 For the variable nuclear tandem repeat surfactant protein B gene polymorphism, patients were fo

28 or inhibited transcriptional activity of the surfactant protein B gene promoter.

29 or-activated receptor gamma was evaluated in surfactant protein B gene regulation.

30 f TTF-1 mediates PKA-dependent activation of surfactant protein B gene transcription.

31 m-tag single nucleotide polymorphisms in the surfactant protein B gene.

32 GF-beta represses transcription of pulmonary surfactant protein-B gene in lung epithelial cells.

33 The studies support the concept that surfactant protein B homeostasis is influenced by neutra

34 s completely abolish expression of the human surfactant protein B (hSP-B) 1.5 kb lacZ reporter gene i

35 Intratracheal treatment with exogenous surfactant protein B improved survival and lung histolog

36 showed no postnatal expansion but had normal surfactant protein B levels.

37 h surfactant protein A, B, and C content and surfactant protein-B mRNA expression in Stat3(DeltaDelta

38 mice was not associated with accumulation of surfactant proteins B or C, or their mRNAs, distinguishi

39 and nanoparticle, chain tilt angle, and the surfactant protein B peptide helix tilt angle.

40 d of a monolayer of palmitic acid (PA) and a surfactant protein B peptide, SP-B(1-25).

41 Preliminary studies have identified pro-surfactant protein B (pro-SFTPB) to be a promising blood

42 e aliquot was used to quantify levels of pro-surfactant protein B (pro-SFTPB), a previously establish

43 thyroid transcription factor (TTF)-1 and pro-surfactant protein-B (pro-SP-B), and mesenchymal (alpha-

44 3 is necessary for lamellar body biogenesis, surfactant protein-B processing, and lung development la

45 Surfactant protein B (Sftpb) is a developmentally regula

46 rowth factor-beta binding protein-4 (LTBP4), surfactant protein B (SFTPB), and transforming growth fa

47 P-2 enhanced the activity of the promoter of surfactant protein-B (Sftpb gene) but not other surfacta

48 and depth of each residue of lung pulmonary surfactant protein B (SP-B(1-25)) in a phospholipid bila

49 Inability to produce surfactant protein B (SP-B) causes fatal neonatal respir

50 ification of structural changes of pulmonary surfactant protein B (SP-B) due to the heterogeneous rea

51 ociated with increased apoptosis and reduced surfactant protein B (SP-B) expression.

52 The rate of loss of surfactant protein B (SP-B) from these preterm animals'

53 ted the -500 to +41 promoter activity of the surfactant protein B (SP-B) gene in respiratory epitheli

54 ming growth factor-beta (TGF-beta) represses surfactant protein B (Sp-B) gene transcription through a

55 Surfactant protein B (SP-B) is a 79-amino acid peptide c

56 Surfactant protein B (SP-B) is a 79-residue essential co

57 Surfactant protein B (SP-B) is a hydrophobic, 79 amino a

58 Surfactant protein B (SP-B) is a small, hydrophobic prot

59 Pulmonary surfactant protein B (SP-B) is an essential protein for

60 Surfactant protein B (SP-B) is detected in the airways a

61 Surfactant protein B (SP-B) is essential for maintenance

62 The lung-specific surfactant protein B (SP-B) is essential for surfactant

63 Surfactant protein B (SP-B) is essential to the function

64 Surfactant protein B (SP-B) is essential to the function

65 Surfactant protein B (SP-B) is one of two helical, amphi

66 Surfactant protein B (SP-B) is required for the maintena

67 Surfactant protein B (SP-B) is secreted into the airspac

68 Human surfactant protein B (SP-B) is synthesized by type II ce

69 Surfactant protein B (SP-B) mRNA and protein are restric

70 Surfactant protein B (SP-B) proprotein contains three sa

71 the 102-amino acid C-terminal propeptide of surfactant protein B (SP-B) was analyzed by characterizi

72 Surfactant protein B (SP-B), a hydrophobic protein of lu

73 from patients with ESRD (ESRD-HDL) included surfactant protein B (SP-B), apolipoprotein C-II, serum

74 tively charged to hydrophobic amino acids in surfactant protein B (SP-B), on the structure and collap

75 esized to resemble the amino acid pattern of surfactant protein B (SP-B).

76 imulations of the N-terminal region of human surfactant protein-B (SP-B(1-25)) in dipalmitoylphosphat

77 ith abnormal surfactant function and reduced surfactant protein-B (SP-B) expression.

78 Inherited deficiency of surfactant protein-B (SP-B) is a fatal autosomal recessi

79 nd use the method to measure the turnover of surfactant protein-B (SP-B).

80 Full length surfactant protein-B (SP-B1-78) (B) and palmitoylated su

81 the E4 promoter replaced by the promoter for surfactant protein B (SPB).

82 mal patterns and numbers of cells expressing surfactant protein-B suggest that differentiation of typ

83 ation, as indicated by lack of expression of surfactant protein B, surfactant protein C, the Clara ce

84 eceptor for advanced glycation end products, surfactant protein-B, type III procollagen, and pro-casp

85 II alveolar epithelial cells were capable of surfactant protein-B uptake and stimulated surfactant re

86 Surfactant protein B was similar in the diagnostic group

87 ptide employed as a functional mimic of lung surfactant protein B, which successfully lowers surface

88 were reduced, with the exception of that for surfactant protein B, which was elevated.

89 nts revealed a specific staining pattern for surfactant protein-B, which was the same pattern observe