ライフサイエンスコーパス: surfactant protein D

1 tion analysis showed that baseline values of surfactant protein D (46.6 ng/mL vs 34.6 ng/mL, p=0.0018

2 KGF treatment increases BAL surfactant protein D, a marker of type II alveolar epith

3 Surfactant protein D also increased phagocytosis of apop

4 monstrate that reduced pulmonary edema fluid surfactant protein D and elevated plasma surfactant prot

5 olar lavage and various serum markers (e.g., surfactant protein D and KL-6) each may provide useful i

6 In a subset, we compared plasma levels of surfactant protein-D and von Willebrand factor antigen b

7 on molecules in the collectin family, namely surfactant proteins D and A (Sp-D and Sp-A, respectively

8 ptor for advanced glycation end products and surfactant protein D) and endothelial injury (angiopoiet

9 s in SP-A than in the homologous collectins, surfactant protein D, and mannose-binding protein.

10 r inhibitor-1 (PAI-1), surfactant protein-A, surfactant protein-D, and intracellular adhesion molecul

11 n molecule-1, von Willebrand factor antigen, surfactant protein-D, and soluble tumor necrosis factor

12 eceptor for advanced glycation end products, surfactant protein D, angiopoietin-2, interleukin-6, int

13 soluble multitrimers of BAFF and APRIL using surfactant protein D as a scaffold, and we vaccinated mi

14 In contrast, pulmonary edema fluid surfactant protein D, but not surfactant protein A, was

15 a levels of fibrinogen, chemokine ligand 18, surfactant protein D, C-reactive protein, Clara cell sec

16 surfactant protein A-deficient (SP-A-/-) or surfactant protein D-deficient (SP-D-/-) BALF, or a mixt

17 multitrimerized using the lung protein SP-D (surfactant protein D), enhancing immune responses.

18 in, which evolved through duplication of the surfactant protein D gene in ruminants, prefers mannose

19 oluble tumor necrosis factor receptor-1, and surfactant protein-D) had nearly equivalent prognostic v

20 ding of three innate immune lectins, namely, surfactant protein D, human galectin-8, and Siglec-14, t

21 nt of peritoneal Mos with the lung collectin surfactant protein D inhibited AC uptake, and fluticason

22 Surfactant protein D is a pattern recognition molecule t

23 Surfactant protein D is characterized by two relatively

24 ated proteins such as endogenous eotaxin and surfactant protein D levels, which were both increased f

25 KGF increased BAL concentrations of surfactant protein D, matrix metalloproteinase (MMP)-9,

26 alysis, we identified four serum biomarkers (surfactant protein D, matrix metalloproteinase 7, CA19-9

27 + carbohydrate recognition domains of human surfactant protein D (NCRD) with CL-43 (RCL-43-NCRD) and

28 re generally not inhibited by the collectins surfactant protein D or mannose binding lectin because o

29 ct of leukoreduced blood on plasma levels of surfactant protein-D or von Willebrand factor antigen wa

30 Surfactant protein D preferentially binds to glucose and

31 es, including von Willebrand factor antigen, surfactant protein D, protein C, plasminogen activator i

32 RATIONALE: Recombinant fragment of human surfactant protein D (rfhSP-D) has been shown to suppres

33 We used here several recombinant human surfactant protein D (RhSP-D) preparations to determine

34 Mice deficient in surfactant protein D (Sftpd) develop progressive age-rel

35 nary and activation-regulated chemokine, and surfactant protein D significantly increased the areas u

36 nary and activation-regulated chemokine, and surfactant protein D significantly strengthens this asso

37 Mice lacking surfactant protein surfactant protein D (SP-D(-/-)) and wild-type mice (SP-

38 tudies reveal that substantial quantities of surfactant protein D (SP-D) accumulate in the airspaces

39 Surfactant protein D (SP-D) and CD14 are important innat

40 Surfactant protein D (SP-D) and serum conglutinin are cl

41 Circulating levels of the biomarkers surfactant protein D (SP-D) and soluble receptor for adv

42 Surfactant protein A (SP-A) and surfactant protein D (SP-D) are high abundance pulmonary

43 Increasing evidence now identifies surfactant protein D (SP-D) as an important element of t

44 Surfactant protein D (SP-D) binds to and agglutinates M.

45 Lung surfactant protein D (SP-D) binds to Mycobacterium tuber

46 Lung surfactant protein D (SP-D) can directly interact with c

47 Targeted ablation of the surfactant protein D (SP-D) gene caused chronic inflamma

48 Targeted ablation of the surfactant protein D (SP-D) gene caused progressive pulm

49 Surfactant protein D (SP-D) gene-targeted mice develop s

50 m mannose-binding lectin (MBL) and pulmonary surfactant protein D (SP-D) have distinctive monosacchar

51 The innate host defense component surfactant protein D (SP-D) interacts with glycans on th

52 Surfactant protein D (SP-D) is a 43-kDa member of the co

53 Surfactant protein D (SP-D) is a collectin family member

54 Surfactant protein D (SP-D) is a member of the collectin

55 Surfactant protein D (SP-D) is a molecule of the innate

56 Surfactant protein D (SP-D) is an important effector of

57 Surfactant protein D (SP-D) is an important regulator of

58 Surfactant protein D (SP-D) is an innate immune effector

59 Surfactant Protein D (SP-D) is an oligomerized C-type le

60 Surfactant protein D (SP-D) is critical for maintenance

61 he recognition of influenza A virus (IAV) by surfactant protein D (SP-D) is mediated by interactions

62 Surfactant protein D (SP-D) is one of two collectins fou

63 Surfactant protein D (SP-D) is preferentially secreted a

64 Our previous studies showed that surfactant protein D (SP-D) is present in human tear flu

65 Surfactant protein D (SP-D) molecules are preferentially

66 Innate immune molecule surfactant protein D (SP-D) plays a critical role in hos

67 Surfactant protein D (SP-D) plays critical roles in host

68 Surfactant protein D (SP-D) plays diverse and important

69 Surfactant protein D (SP-D) plays important roles in ant

70 Surfactant protein D (SP-D) plays important roles in inn

71 Surfactant protein D (SP-D) plays important roles in inn

72 Surfactant protein D (SP-D) plays important roles in lun

73 Recent studies strongly suggest that surfactant protein D (SP-D) plays important roles in pul

74 Surfactant protein D (SP-D) plays important roles in the

75 Surfactant protein D (SP-D) plays roles in pulmonary hos

76 Surfactant protein D (SP-D) plays roles in pulmonary hos

77 previous studies documenting that pulmonary surfactant protein D (SP-D) protects C. neoformans cells

78 recognition domains (CRDs) of lung collectin surfactant protein D (SP-D) recognize sugar patterns on

79 Surfactant protein D (SP-D) shows specific interactions

80 Surfactant protein D (SP-D), a C-type lectin, is an impo

81 Surfactant protein D (SP-D), a component of innate immun

82 Pulmonary surfactant protein D (SP-D), a lung host defense protein

83 Pulmonary surfactant protein D (SP-D), a member of the collectin f

84 Polymorphisms of surfactant protein D (SP-D), an important molecule withi

85 ins, Clara cell secretory protein (CC16) and surfactant protein D (SP-D), and five systemic inflammat

86 The roles of NK cells, surfactant protein D (SP-D), and IFN-gamma, as well as t

87 emonstrated direct interactions of HNPs with surfactant protein D (SP-D), another important effector

88 f a collagenous C-type lectin, rat pulmonary surfactant protein D (SP-D), are sufficient to drive the

89 Surfactant protein D (SP-D), shown to play a role in hos

90 The role of surfactant protein D (SP-D), which inhibits P. aeruginos

91 Surfactant protein D (SP-D)-deficient (SP-D-/-) mice exh

92 t on virulence in naive BALB/c, C57BL/6, and surfactant protein D (SP-D)-deficient mice.

93 a) production and the enhanced expression of surfactant protein D (SP-D).

94 ve and gram-positive bacteria than pulmonary surfactant protein D (SP-D).

95 Surfactant protein-D (SP-D) is a collectin produced in t

96 Pulmonary surfactant protein-D (SP-D) is a member of the collectin

97 Surfactant protein-D (SP-D) participates in several of t

98 The innate immune molecule surfactant protein-D (SP-D) plays an important regulator

99 Surfactant protein-D (SP-D), a member of the "collectin"

100 After challenge with high-dose surfactant protein-D (SP-D)-sensitive influenza A/Philad

101 production, and proteolysis of the collectin surfactant protein-D (SP-D).

102 Surfactant protein D (SPD) plays an important role in su

103 d, a tripartite fusion protein was made from surfactant protein D (SPD), HIV-1 Gag as a test antigen,

104 e was no detectable compensatory increase in surfactant protein D, the other known pulmonary collecti

105 infection, and, when combined with pulmonary surfactant protein D, their antiviral effects were addit

106 exons 1-8 fused to the lectin domain of rat surfactant protein D was used as a substrate.

107 e 2-trimer form, and fusion with the body of surfactant protein D was used to produce the 4-trimer fo

108 Plasma surfactant protein A, but not surfactant protein D, was higher in patients with fewer

109 matrix metalloproteinase (MMP)-7, MMP-1, and surfactant protein D were assessed by ELISA.

110 ombinant homotrimeric fragment of human lung surfactant protein D with a series of bound ligands have