ライフサイエンスコーパス: surveillance mechanism

1 operates in vivo to augment the tumor immune surveillance mechanism.

2 ught to play a significant role in the tumor surveillance mechanism.

3 antibiotics, is controlled by a translation surveillance mechanism.

4 n [MSCI]) and is thought to act as a meiotic surveillance mechanism.

5 be part of a more general spindle checkpoint surveillance mechanism.

6 targeted for destruction by a novel ribosome surveillance mechanism.

7 increased tumorigenicity and can evade tumor surveillance mechanisms.

8 e destruction by macrophage-dependent immune surveillance mechanisms.

9 products that enable evasion of host immune surveillance mechanisms.

10 is and ability to escape p53-dependent tumor surveillance mechanisms.

11 n and differentiation, and diminishing tumor surveillance mechanisms.

12 ified of cases through various reporting and surveillance mechanisms.

13 toward reducing that burden without improved surveillance mechanisms.

14 ns involves both extracellular and cytosolic surveillance mechanisms.

15 gnant cells to resist apoptosis-based tumour-surveillance mechanisms.

16 This may represent one important surveillance mechanism against antinuclear autoimmunity

17 ally sensitize infected cells to this immune surveillance mechanism, an outcome that would have thera

18 el to investigate metastasis-specific immune surveillance mechanisms are also explored.

19 We suggest that these surveillance mechanisms arose when both S and M phases w

20 cing of endogenous coding genes by using RNA surveillance mechanisms as a safeguard to protect their

21 ells exhibited an apparently functional G2-M surveillance mechanism, as exemplified by a lack of both

22 r results provide evidence for a codon-based surveillance mechanism associated with the nucleus that

23 Our results suggest that a transcriptome surveillance mechanism based on random association of RN

24 eteriously activated as cellular defense and surveillance mechanisms break down with age.

25 tive complement pathway (ACP) functions as a surveillance mechanism by which microorganisms are opson

26 tivity before axon wrapping might serve as a surveillance mechanism by which OPCs determine the prese

27 During the meiotic cell cycle, a surveillance mechanism called the "pachytene checkpoint"

28 Defects in a cell cycle surveillance mechanism called the spindle checkpoint con

29 Surveillance mechanisms (checkpoints) exert quality cont

30 We propose that an HDAC-dependent surveillance mechanism counteracts constitutive histone

31 In eukaryotic cells, surveillance mechanisms detect and respond to DNA damage

32 activating Ki-ras mutations may escape tumor surveillance mechanisms due to reduced responsiveness to

33 t NTA by the NatA complex acts as a cellular surveillance mechanism during stress and that imprinting

34 In mammals, surveillance mechanisms eliminate meiotic cells with def

35 hese compartments, but it is unknown whether surveillance mechanisms exist to reinforce this function

36 data suggest that an alternative elongation surveillance mechanism exists in vivo to overcome arrest

37 These findings suggest a novel surveillance mechanism for eliminating cells containing

38 The p53 pathway provides a surveillance mechanism for protein translation as well a

39 ein turnover by Hiw can function as a damage surveillance mechanism for responding to axonal injury.

40 Here we describe a genome surveillance mechanism for retrotransposons by transposa

41 We demonstrate a novel surveillance mechanism for the elimination of cells dama

42 early meiosis, suggesting sexually dimorphic surveillance mechanisms for telomere dysfunction during

43 poptosis induced by p53 are part of the host surveillance mechanisms for viral infection and tumor in

44 lex processes of mRNA biogenesis, these mRNA surveillance mechanisms help to ensure the integrity of

45 n other systems, the RNA life cycle involves surveillance mechanisms, however, the details of RNA qua

46 ay constitute an innate immune translational surveillance mechanism important in host defense counter

47 ediated decay (NMD) is a posttranscriptional surveillance mechanism in eukaryotes that recognizes and

48 Here we show the existence of an innate host surveillance mechanism in macrophages that specifically

49 t distinct responses, providing insight into surveillance mechanisms in male meiosis.

50 d DNA damage response and escape from immune surveillance mechanisms in the pathogenesis of PTCL.

51 nce tumorigenesis, underscoring the powerful surveillance mechanisms in the skin.

52 One such surveillance mechanism is meiotic silencing, the inactiv

53 ne checkpoint gene, which suggests that this surveillance mechanism is widely conserved.

54 Cell cycle checkpoint, a major genomic surveillance mechanism, is an important step in maintain

55 kinetochore-microtubule attachments, a cell surveillance mechanism known as the spindle assembly che

56 Eukaryotic cells rely on a surveillance mechanism known as the spindle checkpoint t

57 In budding yeast, a surveillance mechanism known as the spindle position che

58 In budding yeast, a surveillance mechanism known as the spindle position che

59 Innate immune surveillance mechanisms lie at the heart of the antivira

60 germline apoptosis pathway, and that similar surveillance mechanisms may contribute to germline apopt

61 Existing surveillance mechanisms may underestimate the incidence

62 Therefore, a surveillance mechanism monitors spatial position in resp

63 sults point towards the existence of a novel surveillance mechanism of microtubule integrity that may

64 inding protein is a novel nucleic-acid-based surveillance mechanism of RQC.

65 This review focuses on the surveillance mechanisms of the budding yeast S. cerevisi

66 Our results indicate that host surveillance mechanisms operate at multiple levels to re

67 BLM is likely to be part of a DNA surveillance mechanism operating during S phase.

68 of organisms have unveiled the existence of surveillance mechanisms or checkpoints that couple the f

69 artly monitored by the spindle checkpoint, a surveillance mechanism preventing the cell from prematur

70 The surveillance mechanism responsible for the detection and

71 mination are key to the understanding of RNA surveillance mechanisms such as NMD and crucial for the

72 id genomic instability, cells have developed surveillance mechanisms such as the spindle assembly che

73 We propose the existence of a surveillance mechanism that couples the balanced product

74 in budding yeast, which is part of a nuclear surveillance mechanism that degrades aberrant transcript

75 se-mediated mRNA decay (NMD) is a eukaryotic surveillance mechanism that degrades mRNAs containing pr

76 ons in nonsense-mediated mRNA decay (NMD), a surveillance mechanism that degrades mRNAs with prematur

77 common with nonsense-mediated decay (NMD), a surveillance mechanism that degrades PTC-bearing mRNAs.

78 i by cGAS may act as a cell-intrinsic immune surveillance mechanism that detects a range of neoplasia

79 Nonsense-mediated mRNA decay (NMD) is a surveillance mechanism that detects and degrades transcr

80 NMD is a surveillance mechanism that detects and eliminates aberr

81 SPOC is a surveillance mechanism that ensures alignment of the mit

82 er of the Unfolded Protein Response (UPR), a surveillance mechanism that ensures homeostasis of the e

83 The spindle checkpoint is a cell cycle surveillance mechanism that ensures the fidelity of chro

84 e for cell competition during adulthood as a surveillance mechanism that ensures tissue integrity dur

85 uivalent of mammalian centrosome) associated surveillance mechanism that halts mitotic exit upon spin

86 onsense-mediated mRNA decay (NMD) is an mRNA surveillance mechanism that in mammals generally occurs

87 ive bacteria are specifically detected via a surveillance mechanism that involves activation of extra

88 spindle assembly checkpoint (SAC), a genome-surveillance mechanism that is important for cell surviv

89 NA decay (NMD) pathway is a highly conserved surveillance mechanism that is present in all eukaryotes

90 (p)ppGpp appear to be part of a surveillance mechanism that links nutrient availability

91 cellular response to DNA damage is a crucial surveillance mechanism that maintains genomic integrity

92 MAD1 and MAD2 act in a surveillance mechanism that mediates a metaphase delay i

93 se-mediated mRNA decay (NMD) is a eukaryotic surveillance mechanism that monitors cytoplasmic mRNA tr

94 Our results suggest a novel cell cycle surveillance mechanism that monitors nucleosome assembly

95 mRNA decay (NMD) pathway is an example of a surveillance mechanism that monitors premature translati

96 The spindle assembly checkpoint, a surveillance mechanism that operates in all cells to pre

97 s, an Aurora B gradient appears to mediate a surveillance mechanism that prevents chromosome deconden

98 SAC is the critical surveillance mechanism that prevents premature chromosom

99 sw1 and the nuclear exosome ensures accurate surveillance mechanism that proofreads the efficiency of

100 In summary, we uncover a p53-dependent surveillance mechanism that protects against genome inst

101 les of Nup2 and NupA during mitosis and in a surveillance mechanism that regulates nucleokinesis when

102 interference is an evolutionarily conserved surveillance mechanism that responds to double-stranded

103 ets of nonsense-mediated mRNA decay (NMD), a surveillance mechanism that selectively degrades nonsens

104 protease subunit AFG3L2 is critical to this surveillance mechanism that we propose acts as a sensor

105 DNA damage activates TP53-regulated surveillance mechanisms that are crucial in suppressing

106 underscores the importance of defining tumor surveillance mechanisms that effectively target the dise

107 Large-scale, robust surveillance mechanisms that measure rather than estimat

108 Surveillance mechanisms that monitor protein synthesis c

109 SADD) theory postulates the presence of host surveillance mechanisms that monitor the integrity of co

110 Cell cycle checkpoints are surveillance mechanisms that safeguard genome integrity.

111 Cells rely on surveillance mechanisms that take care of the removal of

112 NGD) and non-stop decay (NSD) are eukaryotic surveillance mechanisms that target mRNAs on which elong

113 Thus, Crb may be part of a "surveillance mechanism" that is responsible for the cell

114 Mitotically dividing cells use a surveillance mechanism, the spindle assembly checkpoint,

115 ecay (NMD) represents a highly conserved RNA surveillance mechanism through which mRNA transcripts be

116 dle assembly checkpoint (SAC) functions as a surveillance mechanism to detect chromosome misalignment

117 g of how HIV subverts a normal immunological surveillance mechanism to establish primary infection.

118 (ATR)-mediated S phase checkpoint acts as a surveillance mechanism to prevent rereplication.

119 Thus, C. elegans has a surveillance mechanism to recognize ToxA through its eff

120 sis, however, thereby providing an efficient surveillance mechanism to sense the loss of Rb.

121 st and apoptosis as part of the overall host surveillance mechanism to ultimately block viral replica

122 This suggests that mammalian hosts possess surveillance mechanisms to monitor pathogen-mediated alt

123 Therefore, cells have evolved surveillance mechanisms to restrict the mobility of thes

124 DNA damage response is an important surveillance mechanism used to maintain the integrity of

125 host cell processes or cause damage, but the surveillance mechanisms used by animals to monitor these

126 nal transduction pathway as part of the host surveillance mechanisms, which ultimately induces the ir

127 A reliable surveillance mechanism would either maintain our confide