ライフサイエンスコーパス: susceptibility

1 tion that plays an important role in disease susceptibility.

2 oral pattern of proliferation and infectious susceptibility.

3 vious reports of a relationship with genetic susceptibility.

4 er of WT platelets did not restore arthritis susceptibility.

5 timing and support causal links with cancer susceptibility.

6 lly protects against squamous cell carcinoma susceptibility.

7 CR or digital PCR to determine antimicrobial susceptibility.

8 he DFR significantly restored the antibiotic susceptibility.

9 modify the atrial substrate and increase AF susceptibility.

10 f each isolate to alter S. aureus antibiotic susceptibility.

11 tal organic matter, grain size, and magnetic susceptibility.

12 ed and nonshared environmental factors to AF susceptibility.

13 of the tumor suppressor, BRCA2, cause cancer susceptibility.

14 rmline variation in the IGH locus in disease susceptibility.

15 of which showed any association with disease susceptibility.

16 eus accumbens (NAc) in depression and stress susceptibility.

17 ease patients and causally linked to colitis susceptibility.

18 ication, and a potential role for individual susceptibility.

19 the interplay of pathogen virulence and host susceptibility.

20 orated by the frequency dependence of its AC susceptibility.

21 ll greatly facilitate studying female stress susceptibility.

22 (v) host-factors that affect bacterial host susceptibility.

23 which could explain how AE3 reduces seizure susceptibility.

24 anomaly does not contribute to the magnetic susceptibility.

25 n accompanied by major increases in pathogen susceptibility.

26 pping to the same domain evoke opposing drug susceptibilities.

27 IL-1Ra treatment reduced seizure susceptibility 2 weeks after TBI compared with vehicle,

28 or (1) detecting the source of developmental susceptibility, (2) identifying mechanisms leading to pa

29 o previously reported associations with COPD susceptibility (4q31 near HHIP and 15q25 near CHRNA5) an

30 might be different genetic factors affecting susceptibility across ancestry groups.

31 pearance of a distinct resonance in the spin susceptibility across the cuprates, iron-based supercond

32 -consuming differentiation of resistance and susceptibility after initial isolation of bacteria from

33 terest, the ATP7B(K832R) Alzheimer's disease susceptibility allele was found, for the first time, to

34 of this study was to identify common genetic susceptibility alleles for gallbladder cancer.

35 ngly, ROS-high NKT cells exhibited increased susceptibility and apoptotic cell death with oxidative s

36 ne mutations contribute to pancreatic cancer susceptibility and are well documented in families in wh

37 them to be modified to incorporate protease susceptibility and biological-recognition motifs for cel

38 In rodents, many stress susceptibility and resilience studies have focused on ma

39 rk, we elucidate the facets of this Mphi Fv3 susceptibility and resistance.

40 g regulatory variants associated with cancer susceptibility and studying their molecular functions, w

41 paminergic medications with the individual's susceptibility, and the underlying neurobiology of Parki

42 aratively few in vitro data on antimicrobial susceptibility are available due to the scarcity of clin

43 echanisms underlying squamous cell carcinoma susceptibility are unclear.

44 law observed in the low-temperature magnetic susceptibility, are consistent with the presence of magn

45 the area of the MR image subjected to metal susceptibility artifacts are then reconstructed from the

46 e the concept of rapid digital antimicrobial susceptibility assessment, we employ the dropFAST platfo

47 chanistic insight into the heightened caries susceptibility associated with CLP and indicate a direct

48 This increased susceptibility at the cellular level manifests as increa

49 We propose that focal breast cancer susceptibility, at least in part, originates from region

50 erproduce L1, but retain aztreonam/inhibitor susceptibility because aztreonam is not an L1 substrate.

51 Antibiotic susceptibility, biofilm formation, Staphylococcal protei

52 have transformed our understanding of glioma susceptibility, but individual studies have had limited

53 arding microbial aetiology and antimicrobial susceptibility, but sub-Saharan Africa lacks diagnostic

54 cluding bacterial identity and antimicrobial susceptibility, but they often require several days of t

55 ated with systemic lupus erythematosus (SLE) susceptibility by a recent genome-wide association study

56 odulating the second-order nonlinear optical susceptibility (chi((2))) of materials at the nanoscale

57 These results suggest that shared genetic susceptibility contributes modestly to MDD and AD comorb

58 e antiaromatic state has a huge paramagnetic susceptibility, despite having no unpaired electrons.

59 ult from a complex interplay between genetic susceptibility, environmental factors, and altered gut m

60 , we conclude that Bim expression is a major susceptibility factor for tumor cell death and, as such,

61 e could further specify genes with increased susceptibility for abnormal gene-transcript behavior by

62 ability to identify individuals at greatest susceptibility for adverse outcomes.

63 alpha2delta-1 subunit function increases the susceptibility for developing diabetes in a sex-dependen

64 tion of exposome studies based on windows of susceptibility for particular target organ systems.

65 we tested the impact of aerobic capacity on susceptibility for progressive liver disease following a

66 vation following trauma exposure reduced the susceptibility for PTSD-like symptoms.

67 Genetic factors significantly influence susceptibility for substance abuse and mood disorders.

68 identity regarding their differentiation and susceptibility for the full lytic cycle of HCMV.

69 e of pregnancy is considered a key window of susceptibility for this outcome.

70 milk-based formula for infants with genetic susceptibility for type 1 diabetes reduced the cumulativ

71 w cytometry workflow to determine carbapenem susceptibility from bacterial cell characteristics in an

72 The identification of AKAP13 as a susceptibility gene for IPF increases the prospect of su

73 lity genes, including OBFC1, a new candidate susceptibility gene for low-grade and borderline serous

74 transcriptional cofactor, as a neuroblastoma susceptibility gene that functions as an oncogene in hig

75 Overall, 17 sudden death-susceptibility gene variants were identified in 12 of 28

76 since the identification of NOD2 as a major susceptibility gene.

77 terations modulated by both inflammation and susceptibility genes for diabetes contribute to beta cel

78 ne DNA was tested for mutations in 25 cancer susceptibility genes using next-generation sequencing.

79 m, regulatory pathways interconnecting human susceptibility genes, biomarkers, proteomes, and transcr

80 iofeatures at each locus predicted candidate susceptibility genes, including OBFC1, a new candidate s

81 of expression of synaptic and schizophrenia-susceptibility genes.

82 ch affected known familial pancreatic cancer susceptibility genes: BRCA2 (12 patients), ATM (10 patie

83 Subjects with susceptibility genotypes for celiac disease and type 1 d

84 contributions of genome-wide variation to AF susceptibility have not been quantified.

85 sed for rapid determination of antimicrobial susceptibility in a wider range of Gram negative and Gra

86 Nitrofurantoin showed >80% susceptibility in all groups.

87 ader social influence versus follower social susceptibility in driving this social order.

88 and are candidates to contribute to obesity susceptibility in humans.

89 amma expression contributes to the infection susceptibility in PRMT1 knock-out mice.

90 on the hypothesis that an underlying genetic susceptibility interacts with folate-sensitive metabolic

91 An analytical model based on field susceptibilities is developed to extract key parameters

92 Collectively, these data indicate that RICD susceptibility is linked to metabolic reprogramming, and

93 levance of microbiome alterations on disease susceptibility is still in its infancy, but the integrat

94 conditions that influence offspring disease susceptibility is warranted to inform targeted early int

95 y is unexplained, indicating that additional susceptibility loci await identification.

96 ng to functionally interpret complex-disease susceptibility loci by GWAS and eQTL integration have pr

97 city, leading to the hypothesis that genetic susceptibility loci for hypertension may serve as predic

98 idence for SMAP1, B3GAT2, and RIMS1 as novel susceptibility loci for pediatric VTE and warrant future

99 ory skin disorder for which multiple genetic susceptibility loci have been identified, but few resolv

100 We identified 25 new susceptibility loci, 3 of which contain integrin genes t

101 The viral determinants of Lv2 susceptibility mapped to the HIV-2 envelope (Env) and ca

102 In this study, we have investigated the susceptibilities of different primary isolates of HIV-1

103 t AML subclones, including differential drug susceptibilities of KRAS mutant and wild-type cells, and

104 s counterbalance the defective PTI and PcBMM susceptibility of agb1-2 plants, and explain the enhance

105 lipoprotein oxidizability, indicative of the susceptibility of apolipoprotein B-containing lipoprotei

106 ppaB signaling, that likely accounts for the susceptibility of BRCA1(mut/+) luminal progenitor cells

107 n factors may contribute to the differential susceptibility of CD4(+) T cells to SIV infection.

108 Further, the relative susceptibility of cells to a metabolic inhibitor is dict

109 vaccine-serotype pneumococci may impact the susceptibility of children to OM progression.

110 We also observed increased susceptibility of cisplatin-resistant cells to NK cell c

111 ight into the role of gene expression in the susceptibility of complex traits and diseases.

112 ubjects) and variants considered to increase susceptibility of disease in 3 larger trio studies (>100

113 ity, respectively, explaining the infectious susceptibility of DOCK8-deficient patients.

114 To assess the susceptibility of each craniofacial articulation to clos

115 ynamics emerge from the site-specific social susceptibility of followers.

116 rferon (IFN-alpha) was shown to increase the susceptibility of HIV-1-infected cells to ADCC despite t

117 We tested the susceptibility of human EC cells to transduction by retr

118 applied to monitor cell viability and screen susceptibility of metabolically active cells (E. coli, B

119 ificance of our research is in examining the susceptibility of minor gallinaceous species to HPAI vir

120 d resulting DNA damage mediate the increased susceptibility of old fibroblasts to IR and chemotherapy

121 by their social influence versus the social susceptibility of others [9].

122 The increased susceptibility of phoQ Salmonella to RNS requires molecu

123 nt cell lines but only partially improve the susceptibility of resistant PDACs to VSV.

124 ensions play a major role in determining the susceptibility of the leaf water transport system during

125 We also present evidence that susceptibility of trees to H. fraxineus is associated wi

126 These data suggest that the susceptibility of U2OS and Saos-2 cells to the DeltaICP0

127 ese gene markers are more robust to identify susceptibility or resilience to several macrophage-relat

128 omated carbapenemase detection, inclusion in susceptibility panels to eliminate delays and subjectivi

129 swelling power, water soluble index, enzyme susceptibility, pasting, gel texture, and thermal proper

130 o determine the prevalence and antimicrobial susceptibility pattern of external ocular bacterial infe

131 least for some patients, depending on local susceptibility patterns of ESBL-E.

132 ures, visual acuity outcomes, and antibiotic susceptibility patterns.

133 Antibiotic susceptibility predictions were fully concordant.

134 e correlates, which indicate that individual susceptibility predisposes towards the expression of dif

135 We established in-vitro and ex-vivo susceptibility profiles for a subset using piperaquine s

136 platform, we can correctly assign antibiotic susceptibility profiles of clinically relevant Gram-nega

137 signaling downstream of the Crohn's disease susceptibility protein nucleotide-binding oligomerizatio

138 yses revealed interactions of CKD-associated susceptibility regions with the transcriptional start si

139 rspecies interaction on S. aureus antibiotic susceptibility remains poorly understood.

140 ene regulation whose contribution to disease susceptibility remains to be fully understood.

141 by effectively designing their antimicrobial susceptibility reports to convey this message.

142 d as indicators of therapeutic resistance or susceptibility, respectively.

143 Inconclusive genotypic susceptibility results for both rifampin and isoniazid w

144 We identify a novel susceptibility signal in the immunoglobulin heavy chain

145 r of post-traumatic astrogliosis and seizure susceptibility.SIGNIFICANCE STATEMENT Epilepsy is a comm

146 reduction in NAc D2-neurons underlies stress susceptibility.SIGNIFICANCE STATEMENT Our study demonstr

147 drug regimen while awaiting second-line drug-susceptibility test (DST) results.

148 Our flow cytometry-assisted susceptibility test (FAST) method combines rapid qualita

149 nce mechanisms in C. difficile and addresses susceptibility test methods and other strategies to coun

150 Drug susceptibility test was done using the Kirby-Bauer Disk

151 spectrometry-based assay for the antifungal susceptibility testing (AFST) of the potentially multidr

152 Antimicrobial susceptibility testing (AST) is a fundamental mission of

153 pecies identification (ID) and antimicrobial susceptibility testing (AST) results for the most common

154 Susceptibility testing indicated that mmpT5 mutations ar

155 The antifungal susceptibility testing of FLC and penicillin revealed th

156 Antimicrobial susceptibility testing of isolates from 4793 domestic an

157 al identification and automated-system-based susceptibility testing straight from the light scatter s

158 n for changes in motility, and antimicrobial susceptibility testing suggested that the Campylobacter

159 understanding of bacteria, developing better susceptibility testing tools, and overcoming obstacles i

160 ctive quantitative measure for antimicrobial susceptibility testing, and determination of minimum inh

161 The total time for antibiotic susceptibility testing, from loading of sample to diagno

162 Compared to the results of phenotypic susceptibility testing, the sensitivity of the assay was

163 ion and automated-system-based antimicrobial susceptibility testing.

164 inical isolates and difficulty in performing susceptibility tests to determine minimum inhibitory con

165 Used alone, without initial susceptibility tests, Rapidec Carba NP can provide posit

166 It underpins the weak susceptibility that the velocity will not change at smal

167 ts also support differential neurobiological susceptibility theory, suggesting that the A allele rend

168 PrP variants exhibiting different pH-induced susceptibilities to aggregation: the susceptible hamster

169 These T-cell subsets exhibit different susceptibilities to the actions of corticosteroids and,

170 e CD4-bound conformation, thereby increasing susceptibility to ADCC.

171 blood telomere length, a potential marker of susceptibility to age-related disease.

172 rying rmtF and aac(6')lb genes, resulting in susceptibility to aminoglycosides.

173 nts in the mechanisms of host resistance and susceptibility to APEC.

174 ed the growth and invasiveness and increased susceptibility to apoptosis.

175 nt M. tuberculosis was dominant and restored susceptibility to APYS1 to wildtype levels.

176 data, yielding improved markers for reduced susceptibility to ash dieback.

177 hough one locus has been implicated in joint susceptibility to asthma and obesity.

178 atory skin disease associated with increased susceptibility to atherosclerosis, provides a clinical h

179 italium and assays to predict the antibiotic susceptibility to azithromycin.

180 ptional responses to bacteria, and increased susceptibility to bacterial adhesion (>3-fold), the epit

181 sequently, Lyst-mutant mice showed increased susceptibility to bacterial infection and were largely r

182 TOR overexpression lines displayed increased susceptibility to both bacterial and fungal pathogens, w

183 xpression, but was inversely correlated with susceptibility to Bruton tyrosine kinase (BTK) and SYK i

184 rther understand pathways critical to cattle susceptibility to bTB and enhance genetic improvement pr

185 The estimated polygenic heritability for susceptibility to bTB was 0.26, 0.37 and 0.34 for phenot

186 w insights into pathways contributing to the susceptibility to CAD in the multi-ethnic populations fr

187 short' QT intervals on the ECG and increased susceptibility to cardiac arrhythmias and sudden death.

188 s12815313-T allele associated with increased susceptibility to CD and UC (OR: 2.12; 95% CI: 1.33, 3.3

189 with pregnancy, an immune state of increased susceptibility to certain infections.

190 onutrient metabolism contribute to increased susceptibility to chronic CS-induced oxidative stress in

191 Ninety isolates (15%, n = 590) with reduced susceptibility to ciprofloxacin were obtained, among whi

192 nt manner, reflecting the genotype-dependent susceptibility to clinical vCJD found in patients.

193 Susceptibility to colitis and influenza A virus infectio

194 Dysbiosis and susceptibility to colitis associated with Nlrp12 deficen

195 ybrid microbiotas and displayed intermediate susceptibility to colitis.

196 imary immunodeficiency manifested in extreme susceptibility to common respiratory RNA viruses.

197 ble-mutant plants exhibited enhanced disease susceptibility to cucumber mosaic virus when the virus-e

198 ere highly stable and showed greatly reduced susceptibility to CYP2D6-mediated metabolism.

199 tic peptide [NT-proBNP]) to predict baseline susceptibility to develop TRCD.

200 eight at birth is associated with subsequent susceptibility to diabetes.

201 among the early mechanisms modulating later susceptibility to diabetes.

202 stent asthma, potentially through modulating susceptibility to early allergic sensitization, upper re

203 nal allergen sensitization affects offspring susceptibility to food allergy, we epicutaneously sensit

204 stem-wide screen to address the frequency of susceptibility to gamma-secretase cleavage among human R

205 eceptor 3 (TLR3) pathway are associated with susceptibility to herpes simplex virus type 1 encephalit

206 of liver CES1 in mice markedly increased the susceptibility to high cholesterol diet-induced liver in

207 studies have uncovered heightened prostatic susceptibility to hormone-induced neoplasia from early-l

208 nsulin clearance, which could increase their susceptibility to hypoglycemia during IIT, contraindicat

209 Specific ChrY variants increase susceptibility to IAV in males and augment pathogenic im

210 In addition, susceptibility to IAV segregates independent of copy num

211 eotide polymorphisms associated with genetic susceptibility to in-hospital acute kidney injury.

212 ate that host AIC regulatory networks confer susceptibility to infection and establish a proteomic re

213 ermine whether antibiotic exposure increases susceptibility to infection by opportunistic pathogens.

214 udy the molecular pathophysiology leading to susceptibility to infection in 3 siblings with severe G6

215 -GvHD therapies that do not adversely affect susceptibility to infection or graft-vs.-tumor immunity

216 An individual's immune function, susceptibility to infection, and response to immunosuppr

217 cated for treatment of SAH, but can increase susceptibility to infection.

218 ich at least partially explain the increased susceptibility to infection.

219 t mucosa, processes that ultimately increase susceptibility to infections and contribute to negative

220 s associated with a considerable increase in susceptibility to infections.

221 for genetic variation in ChrY in regulating susceptibility to infectious disease.

222 rs12252 was not associated with susceptibility to influenza-related critical illness in

223 ain development and impacts inter-individual susceptibility to injury after preterm birth.Inflammatio

224 oxidase-dependent killing and, in turn, host susceptibility to invasive aspergillosis.

225 genotype was also associated with increased susceptibility to latent tuberculosis infection.

226 T cell may offer the best compromise between susceptibility to loss of suppression when exposed to TA

227 andidate-gene association studies on genetic susceptibility to lung cancer have been published over t

228 ut the effects of these infections on infant susceptibility to malaria.

229 ermore, our results suggest that the genetic susceptibility to MDD differs between adult- and earlier

230 These results implicate increased susceptibility to mitochondrial calcium overload in LRRK

231 educed thymic Treg compartment and increased susceptibility to mononuclear infiltrations in the saliv

232 ow catheterization increases an individual's susceptibility to MRSA UTI.

233 R1 expression and activity underlie conidial susceptibility to NADPH (reduced form of nicotinamide ad

234 Antimicrobial susceptibility to natural products could also be easily

235 otocol, demonstrated profound differences in susceptibility to nevus initiation, transformation, tumo

236 hese analyses offer an evaluation of genetic susceptibility to NFT, a common end point for multiple d

237 s and methylation, have been associated with susceptibility to NHL.

238 -related genes that underlie inherited human susceptibility to opportunistic mycoses have significant

239 multicopy ChrY gene families that influence susceptibility to other immunopathological phenotypes, i

240 has hardly been explored due to their higher susceptibility to oxidation in air.

241 ucidate the mechanisms that confer the lower susceptibility to P.falciparum malaria.

242 dependent IFN-gamma immunity associated with susceptibility to paracoccidioidomycosis.

243 , (3) interactions between walking speed and susceptibility to perturbations, when present, were more

244 ts in TACI haploinsufficiency with increased susceptibility to pneumococcal infection.

245 Currently, determining susceptibility to polymyxins is problematic and lengthy.

246 used to determine if the positive charge and susceptibility to posttranslational modifications of the

247 phenotype, the population dynamics, and the susceptibility to predation of a mixotrophic protist thr

248 ating that the gene promotes the Arabidopsis susceptibility to Pst DC3000.

249 ectal cancer) appear to confer resilience or susceptibility to psychopathologies involving prefrontal

250 B to determine whether Nrf2 is a modifier of susceptibility to PTB and prematurity-related morbidity

251 rated JA-mediated resistance and BR-mediated susceptibility to RBSDV infection.

252 tadpole (Lithobates sylvatica) exposure and susceptibility to Ribeiroia ondatrae, based on ecologica

253 hoinositide-regulating protein, to influence susceptibility to Salmonella enterica serovar Typhi (S T

254 causing increased anxiety-like behaviour and susceptibility to seizures.

255 a role for urinary antimicrobial peptides in susceptibility to select uropathogens.

256 iated with an increase in arterial LPS and a susceptibility to sepsis.

257 ction or environmental CRD in mice increased susceptibility to severe intestinal inflammation and epi

258 R3A and POLR3C deficiencies confer increased susceptibility to severe VZV disease in otherwise health

259 The molecular basis of transgene susceptibility to silencing is poorly characterized in p

260 Genetic determinants of susceptibility to silver nanoparticle-induced acute lung

261 ble-strand DNA strand breaks, and pronounced susceptibility to single-strand breakage.

262 Genetics plays an important role in the susceptibility to sporadic colorectal cancer (CRC).

263 including RSPO1 or LGR4, who show increased susceptibility to squamous tumor development.

264 or the adipose PPARgamma-adiponectin axis in susceptibility to stress and negative emotion-related be

265 lated functional adaptations, which underlie susceptibility to stress.

266 6634) have decreased proinsulin staining and susceptibility to T2DM.

267 lectively, these data suggest that increased susceptibility to TB disease could be related to a loss

268 To explore approaches to classify susceptibility to TB, we infected with MTB dendritic cel

269 (ds)RNA sensing, reduced IFN induction, and susceptibility to the common cold virus.

270 the role of arsenic metabolism in individual susceptibility to the development of cancer, cardiovascu

271 rotein gene have been linked to differential susceptibility to the disease in many species.

272 xplains over half of the genetic variance in susceptibility to the Drosophila C virus (DCV) in popula

273 age groups with SARS-CoV and analyzed their susceptibility to the infection.

274 ithin the gene body, and they show different susceptibility to the inhibition of early and immediate

275 es, and certain strains demonstrate in vitro susceptibility to these agents, potentially affording ad

276 depletion of wag31 impacted M. tuberculosis susceptibility to this compound.

277 period, with high reported prevalence of non-susceptibility to treatment advocated by the WHO therape

278 at the cellular level manifests as increased susceptibility to typhoid fever in a Vietnamese populati

279 affects bee health, in part due to increased susceptibility to ubiquitous opportunistic pathogens.

280 bacterial microbiome may be used to predict susceptibility to urinary tract infections and sepsis in

281 d genetic diversity within IFITM3 determines susceptibility to viral disease in humans.

282 iameters, orientations, diffusion rates, and susceptibility values.

283 Most common breast cancer susceptibility variants have been identified through gen

284 ssociations with ER-negative disease for 105 susceptibility variants identified by other studies.

285 Many of these genes were located near IBD susceptibility variants.

286 y regulating DCC, miR-218 may be a switch of susceptibility versus resilience to stress-related disor

287 tained by inducing an effective second order susceptibility via the periodic spatial distribution of

288 Our studies show that DKD susceptibility was linked to mitochondrial dysfunction,

289 ed in 25/38 (65.8%) cases for which colistin susceptibility was tested.

290 ver, to determine if these drugs impact VTDR susceptibility, we need longitudinal data and more cases

291 ultilocus sequence type) and fluoroquinolone susceptibility were determined from whole genome sequenc

292 ast, most antigens that were associated with susceptibility were under neutral selection.

293 Key behavioral outcomes, including susceptibility, were replicated by two independent labor

294 ead, KCNE2 variants may confer proarrhythmic susceptibility when provoked by additional environmental

295 uence of MYB83 significantly increased plant susceptibility, whereas a myb83 mutation rendered the pl

296 ical determinant of spreading depolarization susceptibility with important consequences for neuroinfl

297 ed significant associations with lung cancer susceptibility with strong cumulative epidemiological ev

298 lusion, dAST could accurately determine drug susceptibility within 90 min.

299 and statistical tools, to determine E. coli susceptibility within a few minutes to different antibio

300 Despite marked regional differences in HIV susceptibility within the CNS, there has been surprising