ライフサイエンスコーパス: susceptibility gene

1 gene (FANCT) that also may be a rare cancer susceptibility gene.

2 s a novel pheochromocytoma and paraganglioma susceptibility gene.

3 on (TMLHE), recently identified as an autism susceptibility gene.

4 e TNFSF8 and not TNFSF15 as an important T1R susceptibility gene.

5 with its proposed role as a recessive cancer susceptibility gene.

6 , CHK2 is thought to be a multi-organ cancer susceptibility gene.

7 the SWEET sugar transporter and rice disease susceptibility gene.

8 th BA and zebrafish, GPC1 appears to be a BA susceptibility gene.

9 ng evidence for PTPN2 being a pan-autoimmune susceptibility gene.

10 r test confirmed that ATM is a breast cancer susceptibility gene.

11 domain 1 (TIM1/HAVCR1), an important asthma susceptibility gene.

12 functional, further supporting EN2 as an ASD susceptibility gene.

13 since the identification of NOD2 as a major susceptibility gene.

14 of expression of synaptic and schizophrenia-susceptibility genes.

15 ed to evaluate the functional relatedness of susceptibility genes.

16 l virulence by activating expression of host susceptibility genes.

17 a helpful approach in the search for disease susceptibility genes.

18 ne-sets were novel and previously identified susceptibility genes.

19 (n = 16) of transcription factors among SLE susceptibility genes.

20 n studies (GWASs) to identify additional VTE susceptibility genes.

21 ansporters were significantly enriched among susceptibility genes.

22 ich environmental factors interact with AITD susceptibility genes.

23 , such as BRCA1, RAD51, and Fanconi's anemia susceptibility genes.

24 iological mechanisms and for mapping disease susceptibility genes.

25 pecific phenotyping in the search for asthma susceptibility genes.

26 tions that modulate expression levels of SLE susceptibility genes.

27 al variation in response to RSV and identify susceptibility genes.

28 rvations suggest that PIK3CA and AKT1 are CS susceptibility genes.

29 ardiac channelopathy with 15 elucidated LQTS-susceptibility genes.

30 ce for ARHGAP27 and PLEKHM1 as candidate EOC susceptibility genes.

31 a series of gene-based tests to detect such susceptibility genes.

32 studies to narrow the region and identify BA susceptibility genes.

33 GWA) mapping to identify potential candidate susceptibility genes.

34 association studies have identified >30 SLE susceptibility genes.

35 dies, we estimate between 350 and 400 autism susceptibility genes.

36 hogenic mutations in highly penetrant cancer susceptibility genes.

37 y included SDHA, TMEM127, MAX, and SDHAF2 as susceptibility genes.

38 e, nonsynonymous variants in 99 sudden death-susceptibility genes.

39 come of genetic interaction between multiple susceptibility genes.

40 , and ASAH1 as candidate Parkinson's disease susceptibility genes.

41 germline mutations occurred in eight PCC/PGL susceptibility genes.

42 and loss of Sema3d, two Hirschsprung disease susceptibility genes.

43 TGCT and provide evidence for CMGs as cancer susceptibility genes.

44 ulation of many highly coexpressed human ASD-susceptibility genes.

45 which is one of the most well studied asthma susceptibility genes.

46 Expression of functional breast cancer susceptibility gene 1 (BRCA1) in human breast and ovaria

47 Breast cancer susceptibility gene 1 (BRCA1) is a breast and ovarian ca

48 Breast cancer susceptibility gene 1 (BRCA1) is a tumor suppressor prot

49 Breast cancer susceptibility gene 1 (Brca1), a core protein in DNA-dam

50 antagonists directed against the human tumor susceptibility gene 101 (TSG101) are shown as examples.

51 Tumour susceptibility gene 101 (TSG101) sorts TCRs for inclusio

52 an unbiased shRNA screen that revealed tumor susceptibility gene 101 (TSG101), a component of the end

53 pecific deletion of the rheumatoid arthritis susceptibility gene A20/Tnfaip3 in mice (A20(myel-KO) mi

54 d evidence that coding variants in the known susceptibility gene ABCA7, as well as candidate genes DY

55 More studies are needed to identify host susceptibility genes along with confirmation from functi

56 er germline mutations in other breast cancer susceptibility genes also predispose to TNBC remains to

57 arepsilon3/4 and another Alzheimer's disease susceptibility gene and demonstrate in proof of principl

58 inding protein 2 (IRP2) as an important COPD susceptibility gene and have shown that IRP2 protein is

59 network algorithms as the most probable LQTS-susceptibility gene and involves a conserved residue loc

60 vious implication of Del-1 as a candidate MS susceptibility gene and suggest that Del-1-centered ther

61 We identified 281 candidate susceptibility genes and bioinformatics analyses reveale

62 o support the notion that ethnicity-specific susceptibility genes and process are involved in the pat

63 -specific transcriptional activators of host susceptibility genes and sometimes resistance genes.

64 icrobe intersection, notably several disease susceptibility genes and sterol metabolism pathway compo

65 AD51C and RAD51D are moderate ovarian cancer susceptibility genes and suggest that they confer levels

66 olase 2 (EPHX2) was identified as a novel AN susceptibility gene, and because its protein product, so

67 eptor, muscarinic 2, cardiac) as a candidate susceptibility gene, and mouse strains with a nonsynonym

68 play among the immune system, keratinocytes, susceptibility genes, and environmental factors.

69 ially regulates the expression of Nba2 lupus susceptibility genes, and they suggest an important role

70 sion Germline mutations in pancreatic cancer susceptibility genes are commonly identified in patients

71 Other neuroblastoma susceptibility genes are likely hidden among signals dis

72 Susceptibility genes are necessary but not sufficient to

73 o 9% of all cases of thyroid cancer, but the susceptibility genes are not known.

74 ies identified over half of the HSCR disease susceptibility genes as targets for the sex-determining

75 can 5 (NGC/CSPG5), a potential schizophrenia susceptibility gene, as a critical downstream target of

76 PrimPol has been reported to be a potential susceptibility gene associated with the development of m

77 nables rapid mutation screening for multiple susceptibility genes at once, suggesting that routine cl

78 locus (eQTL) analyses can identify candidate susceptibility genes at risk loci.

79 m, regulatory pathways interconnecting human susceptibility genes, biomarkers, proteomes, and transcr

80 uals who have mutations in the breast-cancer-susceptibility gene BRCA1 (hereafter referred to as BRCA

81 ime, that the familial breast/ovarian cancer susceptibility gene BRCA1 activates the Notch pathway in

82 we address the function of the breast cancer susceptibility gene Brca1 in meiotic silencing and recom

83 The breast cancer susceptibility gene BRCA1 is well known for its function

84 a hypomorphic mutation in the breast cancer susceptibility gene Brca1, a significant reduction in HD

85 The cloning of the breast cancer susceptibility genes BRCA1 and BRCA2 nearly two decades

86 Breast and ovarian cancer susceptibility genes BRCA1 and PALB2 have enigmatic role

87 ethylene glycols selective for breast cancer susceptibility gene (BRCA1) is reported.

88 Mutations in breast cancer susceptibility genes (BRCA1 and BRCA2) are associated wi

89 tentially harmful mutations in breast cancer susceptibility genes (BRCA1 or BRCA2).

90 elected splice variants of the breast cancer susceptibility gene, BRCA1, can be monitored at single-c

91 ch affected known familial pancreatic cancer susceptibility genes: BRCA2 (12 patients), ATM (10 patie

92 LMO1 is a high-risk neuroblastoma susceptibility gene, but how LMO1 cooperates with MYCN i

93 of Xanthomonas exploit a single host disease susceptibility gene by altering the expression of an oth

94 e we set out to identify new high-penetrance susceptibility genes by sequencing 184 melanoma cases fr

95 n drug targets, somatic mutants, and disease susceptibility genes by utilizing directionality and pat

96 tential driver of AS and identified a new AS susceptibility gene, CACNA1C, belonging to the calcium s

97 ion of a single, widely expressed arrhythmia-susceptibility gene can generate a multisystem syndrome

98 functional evidence, we identify several PD susceptibility gene candidates for further investigation

99 We also obtained strong evidence for a new susceptibility gene, CDHR3 (encoding cadherin-related fa

100 functional genes indicates that most cancer susceptibility genes classified into these subgroups do

101 Here we focus on the schizophrenia susceptibility gene DTNBP1 and its product dysbindin, a

102 erturbations downstream of the schizophrenia susceptibility gene DTNBP1 confer susceptibility to copp

103 sociated with mutations in the schizophrenia susceptibility gene dysbindin (dysb), in isolation or in

104 exon-level RNA-Seq, and identified novel SLE susceptibility genes (e.g. NADSYN1 and TCF7) that were c

105 diverse human LCLs enable identification of susceptibility genes (e.g., MX1) for RSV disease severit

106 for assessing the functional relatedness of susceptibility genes, either coding or noncoding, accord

107 Several known breast cancer susceptibility genes encode proteins involved in DNA dam

108 TRAF3IP2 is a candidate psoriasis susceptibility gene encoding Act1, an adaptor protein wi

109 in mice have provided evidence for multiple susceptibility genes, few of these have been confirmed f

110 vival, our data implicate TWEAK as a disease-susceptibility gene for a humoral immunodeficiency.

111 for the SNARE protein SNAP-25 is a candidate susceptibility gene for ADHD, as well as schizophrenia,

112 Complement factor H (CFH) is a major susceptibility gene for age-related macular degeneration

113 ells 2 (TREM2) gene is a recently identified susceptibility gene for Alzheimer's disease (AD), as its

114 ses = 0.0143, MAFcontrols = 0.0089), a known susceptibility gene for Alzheimer's disease.

115 Previously, PTPN22 was described as a susceptibility gene for autoimmunity because it contains

116 We identify WNT7B as a novel susceptibility gene for axial length (rs10453441, Pmeta=

117 AD1L1 (mitotic arrest deficient-like 1) as a susceptibility gene for bipolar disorder and schizophren

118 Our study shows that NRG1 is probably a susceptibility gene for CaD, based on convergent evidenc

119 These data suggest that IL37 is a new susceptibility gene for CAD, which provides a potential

120 Our study supports ISL1 as a major susceptibility gene for CBE and as a regulator of urinar

121 surface molecule HAVCR1/KIM-1 is a suggested susceptibility gene for ccRCC and ectodomain shedding of

122 association study identified IRF4 as a major susceptibility gene for chronic lymphocytic leukemia (CL

123 end products (RAGE) has been identified as a susceptibility gene for chronic obstructive pulmonary di

124 Although SERPINE2 is a candidate susceptibility gene for chronic obstructive pulmonary di

125 reased lung tissue expression of SERPINE2, a susceptibility gene for emphysema.

126 Our results suggested that MICALL2 is a new susceptibility gene for executive inhibition deficiency

127 Our findings suggest that POT1 is a major susceptibility gene for familial melanoma in several pop

128 t of this autoimmune response, is also a key susceptibility gene for GD, probably acting through thym

129 es a small heat-shock protein and is a major susceptibility gene for infestation of wheat by the gall

130 ecruitment domain family member 9 (CARD9), a susceptibility gene for inflammatory bowel disease (IBD)

131 The identification of AKAP13 as a susceptibility gene for IPF increases the prospect of su

132 that catalyzes proteoglycan sulfation, as a susceptibility gene for LDD.

133 lity genes, including OBFC1, a new candidate susceptibility gene for low-grade and borderline serous

134 ain expressed protocadherin 17 (PCDH17) as a susceptibility gene for major mood disorders.

135 in cellular metabolism, FGF21 is a potential susceptibility gene for obesity and type 2 diabetes.

136 oreductase 1 (NQO1) is recognized as a major susceptibility gene for ozone-induced pulmonary toxicity

137 se transporter gene OsSWEET13 as the disease-susceptibility gene for PthXo2 and the existence of cryp

138 This study identified TLL1 as a new susceptibility gene for PTSD.

139 hizophrenia 1 (DISC1) is a leading candidate susceptibility gene for schizophrenia, bipolar disorder

140 tor protein (NOS1AP), a protein encoded by a susceptibility gene for schizophrenia.

141 nnel alpha subunit and is considered to be a susceptibility gene for several neurological disorders w

142 These studies implicate DNER as a susceptibility gene for T2DM in American Indians.

143 NFIL3 is a susceptibility gene for the human inflammatory bowel dis

144 Clec16a has been identified as a disease susceptibility gene for type 1 diabetes, multiple sclero

145 Nedd4l, Ano6, and Rnf220 are candidate susceptibility genes for AgNP-induced lung inflammation

146 ered DPP4, TRHR, and MLF1 as novel candidate susceptibility genes for ASD in the Lebanese.

147 We have identified novel susceptibility genes for asthma and related traits and i

148 We aim to identify susceptibility genes for asthma combined with BHR and an

149 Susceptibility genes for asthma, AR and AD have now been

150 is dependence (CaD) has been established but susceptibility genes for CaD remain largely unknown.

151 Success has been more limited in mapping susceptibility genes for clusters of cardiovascular risk

152 nalysis of the infected brain: We identified susceptibility genes for congenital toxoplasmosis in our

153 The identification of susceptibility genes for coronary artery disease or MI m

154 terations modulated by both inflammation and susceptibility genes for diabetes contribute to beta cel

155 ir receptors, ERBBs, have been identified as susceptibility genes for diseases such as schizophrenia

156 cytes bearing apoptotic IECs overlapped with susceptibility genes for inflammatory bowel disease.

157 icated BATF3, CCDC88B and CIITA-SOCS1 as new susceptibility genes for leprosy.

158 ology of synapses in patient neurons and how susceptibility genes for mental disorders could lead to

159 To identify susceptibility genes for osteoporosis, we conducted an i

160 ngs are consistent with Notch3 and Notch4 as susceptibility genes for ozone-induced lung injury, and

161 of the most prominent and highly replicable susceptibility genes for several neuropsychiatric disord

162 for relative prenatal enrichment of putative susceptibility genes for syndromic neurodevelopmental di

163 However, the identification of definitive susceptibility genes for these etiologically complex dis

164 Cs (hESCs) with mutations in GWAS-identified susceptibility genes for type 2 diabetes.

165 diseases, arising from mutations of disease susceptibility genes (genetic diseases), are also associ

166 a splicing factor regulated by the diabetes susceptibility gene GLIS3, has a major role in maintaini

167 interacts with YIN YANG1 to suppress disease susceptibility genes glutaredoxins GRX480, GRXS13 and th

168 found that participants bearing mutations in susceptibility genes had significantly lower adaptive ab

169 Although a substantial proportion of asthma-susceptibility genes harbour polymorphic CNVs, the major

170 However, the identification of robust PD susceptibility genes has been complicated by phenotypic

171 ons in BRCA1, BRCA2, and other breast cancer susceptibility genes has since proved to be a valuable t

172 tations in the BRCA1 and BRCA2 breast cancer susceptibility genes have been associated with up to 15%

173 Although 16 LQTS-susceptibility genes have been discovered, 20% to 25% of

174 However, evidence for a number of potential susceptibility genes have not so far reached genome-wide

175 here current knowledge about functions of AD susceptibility genes, highlighting cells of the myeloid

176 Among the shared susceptibility genes, HLA-DRbeta1-Arg74 (human leukocyte

177 Human SEMAPHORIN 5A (SEMA5A) is an autism susceptibility gene; however, its function in brain deve

178 as a 50-60% risk contribution from inherited susceptibility genes; however, their exact identity and

179 ons, particularly insulin-dependent diabetes susceptibility genes (Idd)9/11 on chromosome 4, suggesti

180 is study demonstrates that ORMDL3, an asthma susceptibility gene identified by genome-wide associatio

181 isrupted in Schizophrenia 1 (DISC1) is a key susceptibility gene implicated in major mental illnesses

182 NOD2 and ATG16L1 are among the major CD susceptibility genes implicated in impaired immune respo

183 Many ASD susceptibility genes implicated in neuronal pathways/bra

184 olog B) was first identified as a metastasis susceptibility gene in breast cancer through its ability

185 association study identified IRF4 as a major susceptibility gene in chronic lymphocytic leukemia (CLL

186 fied as a gastrointestinal (GI) tract cancer susceptibility gene in multiple Sleeping Beauty DNA tran

187 xenograft model, we identify EPB41 as a HCC susceptibility gene in vitro and in vivo.

188 cross 90% of nucleotides within sudden death-susceptibility genes in 100% of parental exomes from fre

189 ns were identified in 12 of 25 breast cancer susceptibility genes in 26 families without identified B

190 ) has recently led to the discovery of novel susceptibility genes in heritable PAH, but whether WES c

191 ALEs) that activate transcription of disease susceptibility genes in the host, inducing a state of di

192 The importance of susceptibility genes in the risk for dental caries has b

193 32 genes, including known pancreatic cancer susceptibility genes, in DNA prepared from normal tissue

194 n or near previously identified osteoporosis susceptibility genes including ESR1 (6q25.1: rs4869739,

195 nant mutations in adult and pediatric cancer susceptibility genes (including 2 each in TP53, VHL, and

196 iofeatures at each locus predicted candidate susceptibility genes, including OBFC1, a new candidate s

197 studies (GWASs) have identified hundreds of susceptibility genes, including shared associations acro

198 However, most arrhythmia-susceptibility genes, including the KCNE2 K(+) channel b

199 concomitant decreased expression of several susceptibility genes involved in neuroplasticity, includ

200 The main high-penetrance melanoma susceptibility gene is CDKN2A, encoding p16INK4A and p14

201 RCA2 protein, a product of the breast cancer susceptibility gene, is a key recombination mediator tha

202 ional analysis of the major long-QT syndrome-susceptibility genes (KCNQ1, KCNH2, and SCN5A) and catec

203 genetic testing of the 4 major channelopathy-susceptibility genes (KCNQ1, KCNH2, SCN5A, and RYR2) hav

204 .8) with that of the previously suggested DD susceptibility genes KIAA0319, CTNND2, CNTNAP2 and GRIN2

205 ative studies have brought the number of IBD susceptibility gene loci to 163.

206 gene encoding kinesin family member 3A, is a susceptibility gene locus associated with asthma; howeve

207 ssue of Neuron, MacLeod et al. link three PD susceptibility genes, LRRK2, PARK16, and VSP35, to a com

208 Modification of susceptibility genes may provide broad and durable sourc

209 , we show that the combined defect of two UC susceptibility genes, MDR1A and TLR2, sets the stage for

210 shed light on the specific tissues in which susceptibility genes might exert their functions.

211 termine the frequency and spectrum of cancer susceptibility gene mutations among patients with early-

212 Conclusion Germline cancer susceptibility gene mutations are carried by 9.9% of pat

213 risk, yet the prevalence of germline cancer susceptibility gene mutations in patients with CRC unsel

214 These deleterious pancreatic cancer susceptibility gene mutations, some of which are therape

215 e findings identify FANCM as a breast cancer susceptibility gene, mutations in which confer a particu

216 of the validated genes connect to a known AD susceptibility gene network.

217 hocking incident, but the underlying disease susceptibility gene networks remain poorly understood.

218 This includes the ASD susceptibility gene neurexin 1, which showed a distinct

219 otects mice deficient in the Crohn's disease susceptibility gene Nod2 from intestinal abnormalities b

220 Neuregulin 1 (Nrg1) is a susceptibility gene of schizophrenia, a disabling mental

221 i mapping in human valve tissues to identify susceptibility genes of AS.

222 Because NRG1 and ErbB4 are susceptibility genes of schizophrenia, our findings migh

223 Considering that both NRG1 and ErbB4 are susceptibility genes of schizophrenia, our study sheds l

224 and experience in manifesting the impact of susceptibility genes on neuronal development and risk fo

225 sistance gene xa13, an allele of the disease-susceptibility gene Os8N3 (also named Xa13 or OsSWEET11,

226 the promoter region of the bacterial blight susceptibility genes, OsSWEET14 and OsSWEET11, were conf

227 have led to the development of breast cancer susceptibility gene panels for germline genetic testing

228 Although the Parkinson-susceptibility gene, Parkinson protein 7/DJ-1 (DJ-1), ha

229 Our findings identify that the asthma susceptibility gene product CDHR3 mediates RV-C entry in

230 We propose that polymorphisms in susceptibility genes promote disease through defects in

231 lymorphisms that prevent effector binding to susceptibility gene promoters, or that allow effector ac

232 bind to and transcriptionally activate host susceptibility genes, promoting disease.

233 pathway clusters activated by PHEO- and PGL-susceptibility genes: pseudohypoxic, kinase, and Wnt sig

234 matous polyposis-associated mutations in the susceptibility genes PTEN, BMPR1A, SMAD4, ENG, and STK11

235 ied dozens of autism spectrum disorder (ASD) susceptibility genes, raising two critical questions: (1

236 The retinoblastoma susceptibility gene (RB1) was the first tumor suppressor

237 The retinoblastoma tumor susceptibility gene, Rb1, is a key regulator of the cell

238 hat autophagy and inflammatory bowel disease susceptibility genes regulate inflammatory responses to

239 together, we propose Esrrg as a novel lupus susceptibility gene regulating CD4(+) T cell function th

240 However, the identification of definitive TS susceptibility genes remains elusive.

241 Dysbindin is a schizophrenia susceptibility gene required for the development of dend

242 disorders in which the alteration of several susceptibility genes results in dysfunctional mood regul

243 minergic polymorphic ventricular tachycardia-susceptibility gene (RYR2) identified a putative pathoge

244 Each susceptibility gene's tissue involvement was ranked base

245 Our findings extend the list of susceptibility genes shared with Crohn's disease and lep

246 ed ASD genes and uncover novel inherited ASD susceptibility genes specific to the Lebanese.

247 A novel susceptibility gene, ST13, coding for a cochaperone of t

248 N2A, CDK4, and BAP1) and intermediate (MITF) susceptibility genes; statistical effect of histologic s

249 In order to improve power to localize susceptibility genes, stratified linkage analyses were p

250 In the ongoing search for susceptibility genes, studying particular racial groups,

251 de association studies have identified lupus susceptibility genes such as IRF5 and PRDM1 (encoding fo

252 ategorized as an hypertrophic cardiomyopathy susceptibility gene, such that a mouse model can recapit

253 isk is influenced by rare coding variants in susceptibility genes, such as BRCA1, and many common, mo

254 ed and compared to the function of other IBD susceptibility genes, such as Nod2, which encodes a cyto

255 resence of prenatal expression enrichment of susceptibility genes systematically, as composite gene s

256 Taken together, LBD20 is a F. oxysporum susceptibility gene that appears to regulate components

257 ATM is an important cancer susceptibility gene that encodes a critical apical kinas

258 transcriptional cofactor, as a neuroblastoma susceptibility gene that functions as an oncogene in hig

259 stemic autoimmunity and that FAAH is a lupus-susceptibility gene that might regulate this process.

260 y common regulatory elements and predict new susceptibility genes that are biologically meaningful to

261 evelopmental in etiology are associated with susceptibility genes that are relatively upregulated dur

262 Synapsins are epilepsy susceptibility genes that encode phosphoproteins reversi

263 We identified 20 potential schizophrenia susceptibility genes that encode proteins that are the t

264 virulence factors of Liberibacters serve as susceptibility genes that facilitate compatibility (e.g.

265 could instead be "downstream" of the primary susceptibility genes that increase the risk of each dise

266 is also evidence suggesting the existence of susceptibility genes that predispose chronically stresse

267 IDE (insulin-degrading enzyme) as a diabetes susceptibility gene, the relationship between the activi

268 KN2A is the most frequent high-risk melanoma susceptibility gene, the underlying genetic factors for

269 igm is expected to apply to other arrhythmia-susceptibility genes, the majority of which encode ubiqu

270 Dysbindin is an established schizophrenia susceptibility gene thoroughly studied in the context of

271 .3 and SEMA3A as a possible Brugada syndrome susceptibility gene through a Kv4.3 gain-of-function mec

272 can synergize with mutations in other autism susceptibility genes to contribute to the development of

273 s in genes in the steroid pathway and asthma susceptibility genes to exacerbations in children and yo

274 nogaster model system can identify candidate susceptibility genes to guide subsequent studies in huma

275 ase DUSP14 in particular, that are promising susceptibility genes to pulmonary TB.

276 etes in restricted lines of inbred mice, the susceptibility genes to virus-induced diabetes have not

277 results suggest that ADAM12 gene is a novel susceptibility gene underlying both joint destruction an

278 R can evaluate the functional relatedness of susceptibility genes underlying schizophrenia and breast

279 TIONALE: Genetic polymorphisms in the asthma susceptibility gene, urokinase plasminogen activator rec

280 ed intervals and also identify additional CD susceptibility genes using a mapping approach that local

281 ne DNA was tested for mutations in 25 cancer susceptibility genes using next-generation sequencing.

282 Admission to the NICU in those without the susceptibility gene variant at rs17815905 (LOC283710/KLF

283 particular, breast-feeding in those with the susceptibility gene variant at rs6736278 (CAPN14) reduce

284 Overall, 17 sudden death-susceptibility gene variants were identified in 12 of 28

285 e mutational analysis of BrS1- through BrS12-susceptibility genes was performed in 129 unrelated pati

286 Germline findings in cancer susceptibility genes were concordant with the individual

287 ous and splice-site variants in 2 arrhythmia susceptibility genes were identified in 223 individuals

288 Nine candidate FSGS susceptibility genes were identified in our patient coho

289 for mutations in other breast/ovarian cancer susceptibility genes when these genes are analyzed as a

290 in DNA mismatch repair emerged as candidate susceptibility genes whereas those acting in the autopha

291 e existence of further major high-penetrance susceptibility genes, which individually account for >1%

292 ontribute to the regulation of breast cancer susceptibility genes, which is consistent with the effec

293 Genetic analyses have reported numerous BD susceptibility genes, while some variants, such as singl

294 cal member of the Bcl-2 family, as a therapy susceptibility gene with elevated expression in solid an

295 d molecular mechanisms connecting a disorder susceptibility gene with environmental factors remain mo

296 een successfully applied to identify disease susceptibility genes with genetic markers such as micros

297 diseases, suggesting the involvement of many susceptibility genes with small effect sizes.

298 0L as a candidate familial Barrett esophagus susceptibility gene, with a putative role in maintaining

299 ystematically search for schizophrenia (SCZ) susceptibility genes within 49 genomic loci previously i

300 n explained by risk alleles at the psychosis susceptibility gene ZNF804A and its interacting partners