ライフサイエンスコーパス: susceptibility loc(us|i)

1 ncorporating information from common genetic susceptibility loci.

2 heterogeneous, with evidence for hundreds of susceptibility loci.

3 nked to >30 insulin-dependent diabetes (Idd) susceptibility loci.

4 8 cases and 13,970 controls) to identify new susceptibility loci.

5 :03 (Pcombined=1.83 x 10(-9)) as independent susceptibility loci.

6 ysis using Immunochip data have uncovered 36 susceptibility loci.

7 ified numerous common prostate cancer (PrCa) susceptibility loci.

8 wer, leading to the discovery of six new EOC susceptibility loci.

9 mmary, we provide evidence of five novel SLE susceptibility loci.

10 cinoma may be attributable to shared genetic susceptibility loci.

11 heterogeneity to discover additional obesity susceptibility loci.

12 ltiple biologically relevant lupus nephritis susceptibility loci.

13 mapping for detecting previously overlooked susceptibility loci.

14 -1 receptor-like 1 (IL1RL1)/IL18R1 as asthma susceptibility loci.

15 tent not previously observed in other cancer susceptibility loci.

16 tive phenotypes to identify putative disease-susceptibility loci.

17 rlap with previously reported SLE-associated susceptibility loci.

18 reveals a strong enrichment for DMRs in T2D-susceptibility loci.

19 ping studies in the search for CCLE specific susceptibility loci.

20 0(-8), OR 0.89), confirming that both are RA susceptibility loci.

21 mosome 9q21.32 are true diabetic nephropathy susceptibility loci.

22 dies (GWAS) have reported several suggestive susceptibility loci.

23 are causally linked to specific mutagens or susceptibility loci.

24 AS) have identified 140 Crohn's disease (CD) susceptibility loci.

25 ful tool in the investigation of new disease susceptibility loci.

26 nformation has been used to identify genetic susceptibility loci.

27 ments in the fine-mapping resolution at many susceptibility loci.

28 entified multiple renal cell carcinoma (RCC) susceptibility loci.

29 enia (SCZ) in Han Chinese identified several susceptibility loci.

30 eract with the 92 DRE that were found at IBD susceptibility loci.

31 nderstanding the biology of specific disease susceptibility loci.

32 tenic with the human 10q22-q23 schizophrenia-susceptibility locus.

33 the 17q12-21 locus, near a well-known asthma susceptibility locus.

34 ich find the xMHC to be the most significant susceptibility locus.

35 c lupus erythematosus, with IRF8 as a strong susceptibility locus.

36 ve T cells in mice carrying the Sle1a1 lupus-susceptibility locus.

37 We identify an additional four susceptibility loci: 11q23.3 CADM1, a metastasis suppres

38 y proxy points to 27 candidate schizophrenia susceptibility loci, 12 of which are associated with sch

39 from the PDED3 and MED24 genes at the asthma susceptibility locus 17q21 were associated with increase

40 tive immunity and genetic variants on asthma susceptibility locus 17q21.

41 H (CFH) and A69S in age-related maculopathy susceptibility locus 2 (ARMS2).

42 Here we show the discovery of four new BCC susceptibility loci: 2p24 MYCN (rs57244888[C], OR=0.76,

43 We identified 25 new susceptibility loci, 3 of which contain integrin genes t

44 gies have led to the discovery of 242 common susceptibility loci, 45 of which have been fine-mapped t

45 We identified 16 additional psoriasis susceptibility loci achieving genome-wide significance,

46 We identified 18 susceptibility loci achieving genome-wide significance,

47 ls, including 27 new genome-wide significant susceptibility loci and 3 unreported shared risk loci.

48 m six East Asian cohorts to identify new SLE susceptibility loci and better localize known loci.

49 Given previous evidence that certain susceptibility loci and carcinogens are associated with

50 tion between 12 GWAS-identified hypertension-susceptibility loci and cardiotoxicity in a cohort of lo

51 We identified shared susceptibility loci and commonalities in pathways betwee

52 ociations between inflammatory bowel disease susceptibility loci and gene expression.

53 we used an alternative approach to annotate susceptibility loci and identify candidate genes for hum

54 s and Epidemiology (PAGE) study, we identify susceptibility loci and investigate pleiotropy among gen

55 Our results highlight several promising new susceptibility loci and reinforce the importance of lyso

56 We identify new CBD susceptibility loci and show that CBD and PSP share a ge

57 the general population to a potential autism susceptibility locus and a linkage region for dyslexia,

58 e functional landscape of the 11q23.3 glioma susceptibility locus and identify a network of functiona

59 k alleles carried at 27 validated common CRC susceptibility loci), and history of endoscopic examinat

60 our of these regions are known breast cancer susceptibility loci, and four additional regions were fo

61 iously published loci, we discovered six new susceptibility loci, and further gene prioritization ana

62 e 2 diabetes risk variants at 37 established susceptibility loci, and indices of proinsulin processin

63 22.2-22.1 schizophrenia and bipolar disorder susceptibility locus, and additional neurodevelopmental

64 We thus identify a sexually dimorphic IS susceptibility locus, and propose the first functionally

65 pped and examined for enrichment for disease susceptibility loci annotated in the genome-wide associa

66 ; P = .02) and CD2AP (rs9349407; P = .03) AD susceptibility loci are associated with neuritic plaque

67 ether genotypes of 10 recently identified RA susceptibility loci are associated with radiologic sever

68 y the scientific community investigating SLE susceptibility loci as they are more powerful than simpl

69 ciation (GWA) studies-identified lung cancer susceptibility loci assessed, a variant (rs2808630) of t

70 tudies (GWAS) have identified 11 independent susceptibility loci associated with bladder cancer risk.

71 smoking women have previously identified six susceptibility loci associated with lung cancer risk.

72 04 controls, among which we identified 3 new susceptibility loci at 11q12 (rs174549), 6p21 (rs2857595

73 This identified three additional susceptibility loci at 2q13, 8q24.1 and 12q24.31.

74 P<5.0 x 10(-8)) evidence of 4 additional CHD susceptibility loci at 4q31.22 (rs1400558, upstream of E

75 We also identified two novel susceptibility loci at 5q15 near ERAP2 (rs7705093; OR =

76 rited susceptibility to BCP-ALL, identifying susceptibility loci at 7p12.2, 9p21.3, 10q21.2, and 14q1

77 Finally, we identify two EOC susceptibility loci at 9q22.33 (rs1413299 in COL15A1, P(

78 We identified SNPs at 41 new breast cancer susceptibility loci at genome-wide significance (P < 5 x

79 ,000 controls, identifies five new psoriasis susceptibility loci at genome-wide significance (P<5 x 1

80 We have thus identified a novel susceptibility locus at 3p21, and confirmed previous sug

81 inkage analysis, we identified a keratoconus susceptibility locus at 9q34.

82 The CLPTM1L gene lies within a cancer susceptibility locus at chromosome 5p15.33 defined by ge

83 ween the immune system, psoriasis-associated susceptibility loci, autoantigens, and multiple environm

84 y is unexplained, indicating that additional susceptibility loci await identification.

85 d IL1RL1, were previously reported as asthma susceptibility loci, but the effect sizes for these loci

86 reveals that several diseases share multiple susceptibility loci, but there are many nuances.

87 2 was identified recently as a neuroblastoma susceptibility locus, but its mechanistic contributions

88 ested in mapping common and uncommon disease susceptibility loci by focusing on output linking correl

89 ng to functionally interpret complex-disease susceptibility loci by GWAS and eQTL integration have pr

90 or which the goal is to discover new genetic susceptibility loci by leveraging G-E interaction when p

91 eth cells associated with particular genetic susceptibility loci can be used to define specific subty

92 genetic basis of the disease, the identified susceptibility loci can only account for a small portion

93 ts at four established type 2 diabetes (T2D) susceptibility loci (CDKAL1, CDKN2A-B, IGF2BP2 and KCNQ1

94 Many disease susceptibility loci colocalize with DNA regulatory eleme

95 These new TGCT susceptibility loci contain biologically plausible genes

96 d Hrh3 as a positional candidate for the EAE susceptibility locus Eae8.

97 -associated loci, suggesting that additional susceptibility loci exist.

98 nts; in addition, known rheumatoid arthritis susceptibility loci explain only a portion of familial c

99 More than 70 prostate cancer susceptibility loci, explaining approximately 30% of the

100 some 19p13.11 (p = 1.0 x 10(-11) ) as shared susceptibility loci for ALS and FTD-TDP.

101 vances have been made in identifying genetic susceptibility loci for autoimmune diseases, but evidenc

102 s have driven the discovery of more than 300 susceptibility loci for autoimmune diseases.

103 To discover new susceptibility loci for Behcet's disease, we performed a

104 High-penetrance susceptibility loci for breast cancer usually result fro

105 To identify functional susceptibility loci for breast cancer, we interrogated t

106 East Asian women to search for novel genetic susceptibility loci for breast cancer.

107 The recent identification of over 60 susceptibility loci for CAD confirms not only the import

108 d with lupus, potentially harboring distinct susceptibility loci for CCLE.

109 We discuss genetic susceptibility loci for CD and how these affect Paneth c

110 ation studies (GWAS) have identified several susceptibility loci for childhood acute lymphoblastic le

111 Several susceptibility loci for classical Hodgkin lymphoma have

112 ion studies (GWASs) have identified multiple susceptibility loci for colorectal cancer, but much of h

113 To identify additional susceptibility loci for colorectal cancer, here we perfo

114 ociation Studies (GWAS) have identified many susceptibility loci for common diseases, they only expla

115 ssociation studies (GWAS) have revealed many susceptibility loci for complex genetic diseases.

116 wide association study (GWAS) identified two susceptibility loci for congenital heart disease (CHD) i

117 gulatory elements that colocalize with known susceptibility loci for coronary artery disease (CARDIoG

118 Genetic susceptibility loci for Crohn's disease (CD) are numerou

119 ome-wide association study (GWAS) identified susceptibility loci for dengue shock syndrome (DSS) at M

120 ieve the large sample sizes needed to detect susceptibility loci for depression.

121 We identified nine new susceptibility loci for different EOC histotypes: six fo

122 To identify genetic susceptibility loci for DLBCL, we conducted a meta-analy

123 In humans, these genes reside in susceptibility loci for epilepsy, and, in flies, we obse

124 ociation studies (GWAS) have identified four susceptibility loci for epithelial ovarian cancer (EOC),

125 nduct a genome-wide linkage scan to identify susceptibility loci for fibromyalgia.

126 vious candidate gene studies suggested a few susceptibility loci for food allergy, but no study inves

127 ) of Hodgkin's lymphoma (HL) have identified susceptibility loci for HL at 2p16.1, 8q24.21 and 10p14.

128 nal candidate-gene annotation for 37 disease susceptibility loci for human atherosclerotic disease th

129 city, leading to the hypothesis that genetic susceptibility loci for hypertension may serve as predic

130 nochip genotyping array expand the number of susceptibility loci for IBD in Caucasians to 163, but th

131 We correlated these regions with susceptibility loci for IBD.

132 tion studies (GWAS) have identified multiple susceptibility loci for immunoglobulin A nephropathy (Ig

133 Twenty-two previously identified susceptibility loci for individual MetS component traits

134 Genetic studies have identified 163 susceptibility loci for inflammatory bowel disease, most

135 Major susceptibility loci for islet autoantibodies are separat

136 and to investigate relationships with known susceptibility loci for kidney function and lipids.

137 (GWAS) have led to the discovery of several susceptibility loci for leprosy with robust evidence, pr

138 To identify genetic susceptibility loci for MacTel, we performed a genome-wi

139 ubstantially increases the number of genetic susceptibility loci for NSCLP and provides important ins

140 ome-wide interaction study to identify novel susceptibility loci for occupational exposure to biologi

141 ermine whether the identified genes are true susceptibility loci for occupational exposures and wheth

142 udies (GWAS) have identified multiple common susceptibility loci for pancreatic cancer.

143 idence for SMAP1, B3GAT2, and RIMS1 as novel susceptibility loci for pediatric VTE and warrant future

144 We identify two independent susceptibility loci for prostate cancer at 11p15.4 (rs12

145 dies (GWAS) have identified >100 independent susceptibility loci for prostate cancer, including the h

146 in UC patients with the aim of detecting new susceptibility loci for PSC.

147 ve facilitated the identification of over 30 susceptibility loci for rheumatoid arthritis (RA).

148 the MYC oncogene on chromosome 8q24 contains susceptibility loci for several major forms of human can

149 ion studies (GWAS) have identified dozens of susceptibility loci for SU/gout, but few have been condu

150 tion (GWA) studies have reported 19 distinct susceptibility loci for testicular germ cell tumor (TGCT

151 We conducted a meta-analysis to identify new susceptibility loci for testicular germ cell tumor (TGCT

152 ighted SNP-scores were built involving known susceptibility loci for the aforementioned traits (53, 7

153 IoGRAM and METASTROKE, are ongoing to reveal susceptibility loci for their underlying disease-atheros

154 To identify additional susceptibility loci for this common cancer, we conducted

155 To identify further susceptibility loci for this common, complex skin diseas

156 Known genetic susceptibility loci for type 2 diabetes (T2D) explain on

157 studies (GWAS) have identified more than 80 susceptibility loci for type 2 diabetes (T2D), but most

158 to the CF disease-causing gene) and at four susceptibility loci for type 2 diabetes in the general p

159 To identify susceptibility loci for visceral leishmaniasis, we under

160 loss in autism, suggest SPRY3 as a candidate susceptibility locus for autism.

161 encoding fetuin-A, has been identified as a susceptibility locus for diabetes and metabolic syndrome

162 The QTL has further been supported as a susceptibility locus for dyslipidemia and related metabo

163 common mutation, perhaps responsible for the susceptibility locus for genetic generalized epilepsy on

164 y, we observed the first example of a common susceptibility locus for genetic mosaicism, specifically

165 We have therefore identified a new susceptibility locus for HPS.

166 Although no major susceptibility locus for HSV-1 was identified, our resul

167 STAT4 is highly plausible as a susceptibility locus for invasive NTS disease.

168 FTO is the strongest known genetic susceptibility locus for obesity.

169 and 6,661 non-ALL controls, we identified a susceptibility locus for Ph-like ALL (GATA3, rs3824662;

170 roles in neurodevelopment and is a putative susceptibility locus for schizophrenia.

171 We investigated whether the MBOAT7-TMC4 is a susceptibility locus for the development and progression

172 hort of 1,481 individuals and identified two susceptibility loci: for lobar ICH, chromosomal region 1

173 h as discoveries of large numbers of disease susceptibility loci from genome-wide association studies

174 r risk using genome-wide data sets of cancer susceptibility loci, genetic variation, p53 occupancy, a

175 dies have had limited success in identifying susceptibility loci, genome-wide association studies (GW

176 lay between lifestyle risk factors and these susceptibility loci has not been fully elucidated.

177 While numerous genetic susceptibility loci have been identified for clinical Al

178 Over 40 susceptibility loci have been identified for type 1 diab

179 More than 200 susceptibility loci have been identified in populations

180 ory skin disorder for which multiple genetic susceptibility loci have been identified, but few resolv

181 Although several lung cancer susceptibility loci have been identified, much of the he

182 cing dyslipidemia and currently; 157 genetic susceptibility loci have been reported to be associated

183 Several chronic lymphocytic leukaemia (CLL) susceptibility loci have been reported; however, much of

184 Thirteen common susceptibility loci have been reproducibly associated wi

185 have identified common risk variants in >100 susceptibility loci; however, the contribution of rare v

186 Additional susceptibility loci identified at genome-wide significan

187 Susceptibility loci identified by GWAS generally account

188 ion to prioritize candidate genes in disease susceptibility loci identified by GWAS.

189 on in a subset of the 72 known breast cancer susceptibility loci identified through genome-wide assoc

190 Intriguingly, two PBC susceptibility loci identified through genome-wide assoc

191 tudy, we aimed to investigate whether the OA susceptibility loci identified to date are functioning a

192 eritability for PsA, the majority of genetic susceptibility loci identified to date are shared with p

193 ntribution to prostate cancer, with over 100 susceptibility loci identified to date that can explain

194 MR-MEGA to fine-mapping four type 2 diabetes susceptibility loci in 22,086 cases and 42,539 controls

195 to investigate established RA, IBD, and T1D susceptibility loci in AD.

196 olism (VTE) and identified a number of novel susceptibility loci in adults.

197 e we identified a role for nine genes in IBD susceptibility loci in antibacterial autophagy and chara

198 We recently identified ten novel SLE susceptibility loci in Asians and uncovered several addi

199 sing the Immunochip to determine whether IBD susceptibility loci in Caucasians also affect risk in AA

200 Here we map common genetic susceptibility loci in European ancestry women for the N

201 ing regulatory biofeatures at 17 known HGSOC susceptibility loci in FTSECs (P = 3.8 x 10(-30)), OSECs

202 s have been reproducibly identified as major susceptibility loci in large-scale genome-wide associati

203 (GWAS1 and GWAS2), we identified 27 vitiligo susceptibility loci in patients of European ancestry.

204 NXB, and ERBB3, which had been identified as susceptibility loci in previous genome-wide association

205 nd Behcet's disease and exploring additional susceptibility loci in the human leukocyte antigen (HLA)

206 We identify four novel inguinal hernia susceptibility loci in the regions of EFEMP1, WT1, EBF2

207 have not previously been identified as TGCT susceptibility loci in these GWA scans, demonstrating th

208 We evaluated 15-PDGH as a colon cancer susceptibility locus in a three-stage design.

209 diovascular phenotypes, we identify novel AD susceptibility loci, including 2 genome-wide significant

210 s of this study identify three candidate LSL susceptibility loci, including one that appears to be as

211 We have mapped 43 susceptibility loci, including ten new associations.

212 additive interactions between smoking and 12 susceptibility loci, individually and combined as a poly

213 50-IL13 and IL4), and 12q13 (STAT6) as major susceptibility loci influencing the regulation of total

214 cellular structure affected by schizophrenia susceptibility loci is the actin cytoskeleton, an organe

215 spite the large number of identified disease-susceptibility loci, it is not known which loci influenc

216 gene (MGEA5) is a documented human diabetes susceptibility locus, its role in maintaining insulin-gl

217 determine whether, similarly, common cancer susceptibility loci map to genes that have altered frequ

218 A combined analysis identifies new HL susceptibility loci mapping to 3p24.1 (rs3806624; P=1.14

219 A combined analysis identified new susceptibility loci mapping to 3q26.2 (rs10936599, P = 1

220 A combined analysis identified a novel susceptibility locus mapping to 2q22.3 marked by rs12105

221 tified the human/rat-conserved breast cancer susceptibility locus MCS5A/Mcs5a.

222 o date, but the identification of additional susceptibility loci might be important to enhance our un

223 pots were enriched in breast cancer germline susceptibility loci (odds ratio (OR) = 4.28) and breast-

224 addition to PLG, the currently known shared susceptibility loci of CAD and periodontitis, ANRIL and

225 Several susceptibility loci of differentiated thyroid cancer (DT

226 , including SLC25A39 and SLC25A40, reside in susceptibility loci of severe forms of epilepsy.

227 ned interactions between smoking and obesity susceptibility loci on BMI.

228 GWAS have identified a breast cancer susceptibility locus on 2q35.

229 report the discovery of a new endometriosis susceptibility locus on 4q12 (rs17773813[G], OR=1.28; P=

230 imity to the previously reported lung cancer susceptibility locus on 6q.

231 ols of Japanese populations, we identified a susceptibility locus on chromosome 15q24.

232 A previous GWAS reported a possible TGCT susceptibility locus on chromosome 1q23 in the UCK2 gene

233 tudies uncovered a major atrial fibrillation susceptibility locus on human chromosome 4q25 in close p

234 In addition to revealing two new TGCT susceptibility loci, our results continue to support the

235 Our joint analysis identifies new ESCC susceptibility loci overall as well as a new locus uniqu

236 genetic variation at CSMD1, a schizophrenia susceptibility locus, plays a role in the ratio between

237 Furthermore, among 21 breast cancer susceptibility loci previously established in European p

238 These susceptibility loci provide deeper insight into the path

239 We describe six new susceptibility loci reaching a genome-wide threshold of

240 previously reported loci and identify 14 new susceptibility loci reaching genome-wide significance (P

241 hisms (SNPs) in 67 independent breast cancer susceptibility loci recently identified by genome-wide a

242 These observations suggest that OA susceptibility loci regulate the level of DNA methylatio

243 ty and function of the causal genes in these susceptibility loci remain, however, elusive.

244 diabetes predisposition at most established susceptibility loci remains poorly understood.

245 not only confirmed the association of a PrCa susceptibility locus, rs11672691 on chromosome 19, but a

246 Ultimately, we identified a NSCL/P susceptibility loci (rs17095681 at 10q25.3, intron of SH

247 Two GVHD susceptibility loci (rs17114803 and rs17114808) within t

248 de association study (GWAS) has identified a susceptibility locus (rs41270488) for HPV8 seropositivit

249 scovery of the first genome-wide significant susceptibility locus (rs4769613; P = 5.4 x 10(-11)) in 4

250 es of rheumatoid arthritis (RA) identified a susceptibility locus, rs874040(CC), which implicated the

251 ormatics using all 82 loci revealed that SLE susceptibility loci share many gene regulatory features,

252 -DR2 and HLA-DR3, two well established lupus susceptibility loci, showed evidence of association with

253 e Pbx1 that corresponds to the NZM2410 lupus susceptibility locus Sle1a1.

254 ar germ cell tumor (TGCT) have identified 18 susceptibility loci, some containing genes encoding prot

255 To identify susceptibility loci specific to ER-negative disease, we

256 dies (GWAS) in PSC have detected a number of susceptibility loci that also show associations in UC an

257 and we discover novel etiologically relevant susceptibility loci that are invisible to standard singl

258 y identified four novel diabetic nephropathy susceptibility loci that have subsequently been shown to

259 ically analyze chromatin-interactions at IBD susceptibility loci that localize to regulatory DNA.

260 , our integrated analyses highlight a set of susceptibility loci that might subserve a shared molecul

261 e polymorphisms in lncRNAs, such as the 9p21 susceptibility locus that encodes the lncRNA antisense n

262 In addition to identifying a new melanoma-susceptibility locus, this is to our knowledge the first

263 and progression of DR, the identification of susceptibility loci through candidate gene approaches, l

264 f colorectal cancer (CRC) have identified 23 susceptibility loci thus far.

265 renal cell cancer (RCC) have identified four susceptibility loci thus far.

266 for all phenotypes conferred by murine viral susceptibility locus Tmevp3.

267 e a mouse model based on the human psoriasis susceptibility locus TNIP1, also referred to as ABIN1, w

268 WAS) have mapped multiple independent cancer susceptibility loci to chr5p15.33.

269 thnic GWAS is still useful to identify novel susceptibility loci to complex traits not only for ethni

270 studies have identified not only hundreds of susceptibility loci to immune-mediated diseases but also

271 cts demonstrated a high tendency for leprosy susceptibility loci to show association with autoimmunit

272 nt with previous genetic mapping of teratoma susceptibility loci to the region containing Gfra1.

273 Known susceptibility loci together can only explain about 6-8%

274 were coupled to position a new hypertension-susceptibility locus, uncovering a previously unsuspecte

275 report a fine-mapping analysis of the 9q31.2 susceptibility locus using 43 160 cases and 42 600 contr

276 NKX2-1 and DIRC3) and identified seven novel susceptibility loci (VAV3, PCNXL2, INSR, MRSB3, FHIT, SE

277 ly, the aggregated effect of all 170 disease susceptibility loci was not associated with disease prog

278 cdkn2c gene encoding p18(INK4c) within a SLE susceptibility locus was found to account for reduced p1

279 To identify new susceptibility loci, we carried out a genetic study of m

280 To identify additional CLL susceptibility loci, we conducted a GWAS and performed a

281 To identify additional BCP-ALL susceptibility loci, we conducted a GWAS and performed a

282 To identify additional FL susceptibility loci, we conducted a large-scale two-stag

283 To identify new glioma susceptibility loci, we conducted a meta-analysis of fou

284 To identify novel CRC susceptibility loci, we conducted a new GWAS and perform

285 To identify additional CLL susceptibility loci, we conducted the largest meta-analy

286 tter understand the genetic basis of the MHC susceptibility loci, we genotyped 7,264 MHC SNPs in 22,6

287 To further discover new susceptibility loci, we imputed data from four GWAS of A

288 To identify new susceptibility loci, we performed a meta-analysis of 11

289 In this study, to identify new ER-negative susceptibility loci, we performed a meta-analysis of 11

290 To identify new susceptibility loci, we performed meta-analysis on genom

291 To identify an additional RCC common susceptibility locus, we conducted a GWAS and performed

292 l dissection of the CD33 Alzheimer's disease susceptibility locus, we found that the rs3865444(C) ris

293 gle nucleotide polymorphisms (SNPs) at these susceptibility loci were associated with diabetic nephro

294 Twenty-three new susceptibility loci were identified at association P < 5

295 Twenty-three new prostate cancer susceptibility loci were identified at genome-wide signi

296 Four novel susceptibility loci were identified with genome-wide sig

297 After adjusting for these factors, 100 susceptibility loci were identified.

298 n the allele frequencies and effect sizes of susceptibility loci, which we use to interpret the volum

299 We identified 16 shared susceptibility loci with association P<5x10(-8), includi

300 We increased the number of susceptibility loci with genome-wide significant associa