ライフサイエンスコーパス: susceptibility locus

1 fied TRAF1/C5 as a rheumatoid arthritis (RA) susceptibility locus.

2 connection between alpha-syn and another PD susceptibility locus.

3 ce that the IL2RA/CD25 gene represents a JIA susceptibility locus.

4 lable data and to identify a new keratoconus susceptibility locus.

5 the -707 site within the CRP gene is an SLE susceptibility locus.

6 s also a candidate in the murine Sle1c lupus susceptibility locus.

7 , was identified as a second Crohn's disease susceptibility locus.

8 cates a wide region and at least one disease-susceptibility locus.

9 96 x 10(-5)) tagged the PARK10 late-onset PD susceptibility locus.

10 the 17q12-21 locus, near a well-known asthma susceptibility locus.

11 e uncertainty surrounding the actual T1D MHC susceptibility locus.

12 pproach that models the marginal effect of a susceptibility locus.

13 ablishing its importance as a major vitiligo susceptibility locus.

14 closely flanking gene may be a tuberculosis-susceptibility locus.

15 owel disease (IBD), and TNF maps to the IBD3 susceptibility locus.

16 there is no convincing evidence of a common susceptibility locus.

17 tenic with the human 10q22-q23 schizophrenia-susceptibility locus.

18 autism families indicate the existence of a susceptibility locus.

19 precise chromosomal location for the disease-susceptibility locus.

20 ge disequilibrium of a marker with a disease susceptibility locus.

21 ich find the xMHC to be the most significant susceptibility locus.

22 c lupus erythematosus, with IRF8 as a strong susceptibility locus.

23 tion that we have mapped to the Sle2c1 lupus susceptibility locus.

24 gene cluster on chromosome 2q37.1 as a novel susceptibility locus.

25 ocus of the NZM2410-derived Sle1 major lupus susceptibility locus.

26 ve T cells in mice carrying the Sle1a1 lupus-susceptibility locus.

27 oding CIKS has recently been identified as a susceptibility locus.

28 cate the orthologous human gene as a disease susceptibility locus.

29 B cells from mice carrying the Sle2c1 lupus susceptibility locus.

30 n ortholog of Ema, is a candidate autoimmune susceptibility locus.

31 cript that mapped to the human breast cancer susceptibility locus 17q12-q21 with unknown function.

32 from the PDED3 and MED24 genes at the asthma susceptibility locus 17q21 were associated with increase

33 tive immunity and genetic variants on asthma susceptibility locus 17q21.

34 H (CFH) and A69S in age-related maculopathy susceptibility locus 2 (ARMS2).

35 Previously, we localized PSORS2 (psoriasis susceptibility locus 2) to chromosomal region 17q25.3-qt

36 etiological heterogeneity, with each genetic susceptibility locus accounting for only a small fractio

37 PSORS1 is the major susceptibility locus, accounting for approximately 33%-5

38 for linkage or association between a disease-susceptibility locus and a chromosome region in which se

39 the general population to a potential autism susceptibility locus and a linkage region for dyslexia,

40 perties of the networks, an established COPD susceptibility locus and domain-domain interactions invo

41 e functional landscape of the 11q23.3 glioma susceptibility locus and identify a network of functiona

42 in AFF2 may be a previously unrecognized ASD susceptibility locus and may help explain some of the ma

43 22.2-22.1 schizophrenia and bipolar disorder susceptibility locus, and additional neurodevelopmental

44 d within a recently mapped human lung cancer susceptibility locus, and association of the p34 A/G SNP

45 We thus identify a sexually dimorphic IS susceptibility locus, and propose the first functionally

46 enetic evidence that EN2 might act as an ASD susceptibility locus, and they suggest that a risk allel

47 , we identified a 7 Mb interval containing a susceptibility locus (ANE1) in a family segregating recu

48 cases and 6732 controls, we identified a new susceptibility locus associated with overall PrCa risk a

49 , and confirmed the existence of a novel SLE susceptibility locus at 12q24 (designated "SLEB4") that

50 tudy provided evidence for a prostate cancer-susceptibility locus at 1q24-25.

51 n both subpopulations, and evidence of a new susceptibility locus at 2q37 was found in S2.

52 We have thus identified a novel susceptibility locus at 3p21, and confirmed previous sug

53 is result indicated that the type 2 diabetes susceptibility locus at 3q27 influences both genetic pre

54 We identified a new susceptibility locus at 4q22.1 in FAM13A and replicated

55 A candidate susceptibility locus at 6q23-25 for lung cancer was rece

56 leading to the identification of a confirmed susceptibility locus at 9p22 (in BNC2).

57 inkage analysis, we identified a keratoconus susceptibility locus at 9q34.

58 A novel RA susceptibility locus at AFF3 was identified with convinc

59 The location of a schizophrenia susceptibility locus at chromosome 22q11 has been sugges

60 The CLPTM1L gene lies within a cancer susceptibility locus at chromosome 5p15.33 defined by ge

61 ve colitis and identify a previously unknown susceptibility locus at ECM1.

62 In addition, we identified a new asthma susceptibility locus at PYHIN1, with the association bei

63 vidence supporting the presence of an asthma susceptibility locus at the proximal end of chromosome 1

64 e attributed to strong LD to another class I susceptibility locus (B*4403).

65 that the IL4RA gene is an atopy- and asthma-susceptibility locus but that variation outside the codi

66 2 was identified recently as a neuroblastoma susceptibility locus, but its mechanistic contributions

67 AP, a gene adjacent to the familial melanoma susceptibility locus CDKN2A on 9p21 (rs4636294, combined

68 The diabetes susceptibility locus (chromosome 18p11) was systematical

69 type 2 diabetes and are consistent with one susceptibility locus common to obesity and diabetes.

70 Linkage to 17q22 syntenic to a susceptibility locus common to two experimental rat mode

71 Landers and Kruglyak), the power to detect a susceptibility locus could drop from 83.6% under a one-l

72 on studies (GWAS) have heralded a new era in susceptibility locus discovery in complex diseases.

73 d Hrh3 as a positional candidate for the EAE susceptibility locus Eae8.

74 A major JME susceptibility locus (EJM1) was mapped to chromosomal re

75 en demonstrated that fine-scale mapping of a susceptibility locus for a complex disease can be accomp

76 gene encoding complement factor 5 (C5) as a susceptibility locus for allergen-induced airway hyperre

77 These complex regions contain more than one susceptibility locus for allergic disease.

78 original hypothesis, that ABCR is a dominant susceptibility locus for AMD, by screening 1,218 unrelat

79 es identified chromosome 1q32 as harboring a susceptibility locus for AMD.

80 he IL4RA gene was examined as the 16p-linked susceptibility locus for asthma and atopy.

81 The authors recently mapped a susceptibility locus for autism to chromosome region 2q2

82 loss in autism, suggest SPRY3 as a candidate susceptibility locus for autism.

83 n orthologue of ema, Clec16A, is a candidate susceptibility locus for autoimmune disorders, and its e

84 ajor histocompatibility complex and AITD1, a susceptibility locus for autoimmune thyroid disease.

85 sults provide an example of a shared genetic susceptibility locus for bipolar disorder and MDD.

86 esults provide evidence of the presence of a susceptibility locus for BN on chromosome 10p.

87 These results strongly implicate 6q25.1 as a susceptibility locus for breast cancer.

88 romosome 6D3 and on human chromosome 3p14, a susceptibility locus for cancer and epilepsy.

89 ting cell growth suggests that PEG3 may be a susceptibility locus for cancer as well as neurobehavior

90 A susceptibility locus for coronary artery disease (CAD) a

91 A susceptibility locus for coronary artery disease (CAD) h

92 ars, which suggests that this locus may be a susceptibility locus for developing RA later in life.

93 encoding fetuin-A, has been identified as a susceptibility locus for diabetes and metabolic syndrome

94 The QTL has further been supported as a susceptibility locus for dyslipidemia and related metabo

95 ugh the p16INK4a locus is the most prominent susceptibility locus for familial melanomas, the low fre

96 Thus, a heretofore unidentified genetic susceptibility locus for FHBL may reside on chromosome 3

97 ntitative trait mapping in mice identified a susceptibility locus for gallstones (Lith6) spanning the

98 common mutation, perhaps responsible for the susceptibility locus for genetic generalized epilepsy on

99 y, we observed the first example of a common susceptibility locus for genetic mosaicism, specifically

100 We have therefore identified a new susceptibility locus for HPS.

101 Although no major susceptibility locus for HSV-1 was identified, our resul

102 Beta(2)-adrenergic receptor (beta2-AR) is a susceptibility locus for hypertension, and polymorphisms

103 STAT4 is highly plausible as a susceptibility locus for invasive NTS disease.

104 kers in the VTCN1 gene defined an additional susceptibility locus for JIA and implicates a novel path

105 ed with corneal malformation, is a potential susceptibility locus for keratoconus.

106 A major susceptibility locus for leprosy has recently been mappe

107 e analysis consolidates clear evidence for a susceptibility locus for LOAD on 10q21.2.

108 indings support previous evidence of a major susceptibility locus for lung cancer and suggest that li

109 strongly implicated by genetic studies as a susceptibility locus for major mental illnesses.

110 histocompatibility molecules are the primary susceptibility locus for many autoimmune disorders, incl

111 esults confirm that MC1R is a low-penetrance susceptibility locus for melanoma, show that pigmentatio

112 We identified a new susceptibility locus for meningioma at 10p12.31 (MLLT10,

113 resent study thus identifies a novel genetic-susceptibility locus for MI and provides a framework for

114 kocyte antigen (HLA) region is the strongest susceptibility locus for MS, but a genome-wide associati

115 oci, none overlaps with the newly identified susceptibility locus for myocardial infarction and coron

116 P = 1 x 10(-65)]; this interval represents a susceptibility locus for nephropathy.

117 FTO is the strongest known genetic susceptibility locus for obesity.

118 ased studies that indicated that SLC1A1 is a susceptibility locus for OCD.

119 1 (LOD=2.55) overlapping a recently reported susceptibility locus for ocular and cutaneous melanoma i

120 and 6,661 non-ALL controls, we identified a susceptibility locus for Ph-like ALL (GATA3, rs3824662;

121 (GeneQuest) identified a significant genetic susceptibility locus for premature myocardial infarction

122 rgely from Irish pedigrees, indicates that a susceptibility locus for psoriasis maps to chromosome 4q

123 PSORS1 is the major susceptibility locus for psoriasis vulgaris (PV) and lie

124 n leukocyte antigen-C gene likely contains a susceptibility locus for psoriasis.

125 At least 1 additional non-DRB1 susceptibility locus for RA exists in an interval that e

126 The identification of a susceptibility locus for refractive error on 15q25 will

127 chromosome 11q13.3, recently identified as a susceptibility locus for renal cell carcinoma, modulates

128 omplementary evidence for chromosome 8p as a susceptibility locus for schizophrenia, and suggest that

129 tion groups provide convergent support for a susceptibility locus for schizophrenia--and, more recent

130 rical P value of.012) and represents a novel susceptibility locus for schizophrenia.

131 roles in neurodevelopment and is a putative susceptibility locus for schizophrenia.

132 itin-modifying enzyme A20, is an established susceptibility locus for SLE.

133 Recent linkage studies mapped a susceptibility locus for stuttering to chromosome 12 in

134 Sle is a susceptibility locus for systemic autoimmunity derived f

135 nectin gene is located in chromosome 3q27, a susceptibility locus for T2DM and metabolic disorders (S

136 The susceptibility locus for the autoimmune disease lupus on

137 We investigated whether the MBOAT7-TMC4 is a susceptibility locus for the development and progression

138 OXP2 has also been considered as a potential susceptibility locus for the language deficits in autism

139 ngenic mapping in NOD mice have identified a susceptibility locus for type 1 diabetes, Idd5.1 on mous

140 an chromosome 3q27, recently identified as a susceptibility locus for type 2 diabetes and the metabol

141 udies in Mexican-Americans localized a major susceptibility locus for type 2 diabetes, NIDDM1, to chr

142 esent cohort with UC, IBD5 may also act as a susceptibility locus for UC (chi2=8.10; P=.002).

143 n combination with KITLG, the strongest TGCT susceptibility locus found to date, men with TGCT had gr

144 ently, we demonstrated that the Friend virus susceptibility locus, Fv2, which is required for the exp

145 Strong statistical evidence for a 13q32 BIP susceptibility locus has been reported.

146 We identified a major susceptibility locus (HIVAN4) on chromosome 6 G3-F3, wit

147 gnosis of type 1 diabetes, sex, or the major susceptibility locus, HLA class II, remain mostly unexpl

148 pport for the existence of a prostate cancer-susceptibility locus HPC20 at 20q13.

149 has provided evidence for a prostate cancer-susceptibility locus, HPC20, which maps to 20q13.

150 chromosome 4 containing the type 1 diabetes susceptibility locus Idd9.2.

151 date for the type 1 diabetes mellitus (T1DM) susceptibility locus IDDM2.

152 orthologous to human 5q11.2, a breast cancer susceptibility locus identified in multiple genome-wide

153 Sle3/5 is a lupus susceptibility locus identified on mouse chromosome 7 of

154 hese results demonstrate evidence for a PRCA susceptibility locus in a subset of families that is dis

155 We evaluated 15-PDGH as a colon cancer susceptibility locus in a three-stage design.

156 implicated 10q22-q23 as a schizophrenia (SZ) susceptibility locus in Ashkenazi Jewish (AJ) and Han Ch

157 inkage studies yielded strong evidence for a susceptibility locus in HPC families.

158 disease has been used to identify a novel RA susceptibility locus in humans.

159 The results identify a novel mammary tumor susceptibility locus in mice and support a role for DMBT

160 d linkage analysis to identify a major HIVAN susceptibility locus in mouse, HIVAN1.

161 on of chromosome 7 was identified as a lupus susceptibility locus in MRL/Fas(lpr) mice as Lmb3.

162 Sle1 is a major lupus susceptibility locus in NZM2410 lupus model that is asso

163 67 has recently been identified as an asthma susceptibility locus in subjects of European ancestry bu

164 ted significant evidence for a schizophrenia susceptibility locus in the Ashkenazim on chromosome 10q

165 We previously identified a disease-susceptibility locus in the BBDR rat, iddm4, which is as

166 he syntenic region of the glomerulosclerosis susceptibility locus in the BUF/Mna rat.

167 stablished the presence of a major psoriasis-susceptibility locus in the human leukocyte antigen (HLA

168 he interval containing PSORS1, the psoriasis-susceptibility locus in the major histocompatibility com

169 Sle1 is a major susceptibility locus in the NZM2410 murine model of syst

170 In earlier studies of the Iddm14 diabetes susceptibility locus in the rat, we identified an allele

171 nteraction between the major prostate cancer susceptibility locus in the subregion of 8q24 that conta

172 that the HLA region harbors a predominant CD-susceptibility locus in these Finnish families.

173 Identification of a susceptibility locus in this region may eventually lead

174 These results localize a major susceptibility locus influencing lung cancer risk to 6q2

175 The mouse T1D susceptibility locus insulin-dependent diabetes suscepti

176 xpected genotypic frequencies (delta) at the susceptibility locus is a function of the susceptibility

177 The 19p13.1 breast cancer susceptibility locus is a modifier of breast cancer risk

178 gene (MGEA5) is a documented human diabetes susceptibility locus, its role in maintaining insulin-gl

179 es have clearly identified a primary disease susceptibility locus lying within the major histocompati

180 This is the first time that an arthritis susceptibility locus mapped in experimental animal model

181 A combined analysis identified a novel susceptibility locus mapping to 2q22.3 marked by rs12105

182 Evidence has been presented for an RA susceptibility locus mapping under the linkage peak on 6

183 lated macular degeneration (AMD) wherein the susceptibility locus maps to chromosome 12q, a region be

184 genetic studies suggest that a schizophrenia susceptibility locus maps to chromosome 22q.

185 It is therefore clear that a schizophrenia susceptibility locus maps to chromosome 22q11.

186 tified the human/rat-conserved breast cancer susceptibility locus MCS5A/Mcs5a.

187 ed with the lpr mutation or the murine lupus susceptibility locus Nba2 causes dramatic B cell and PC

188 Given that the murine lupus susceptibility locus Nba2 includes the IFN-regulated gen

189 The murine lupus susceptibility locus Nba2 on chromosome 1 and the synten

190 We found significant evidence that a susceptibility locus near the marker D10S587 on chromoso

191 With these data, we identified a susceptibility locus near TIMP3 (overall P = 1.1 x 10(-1

192 out, but apart from the well-established HLA susceptibility locus, none of the reported significant r

193 he power of this study was >0.95 to detect a susceptibility locus of lambda(s)= 3 with a genome-wide

194 While the Sle1 lupus susceptibility locus of NZM2410/NZW origin leads to chro

195 tion studies have identified a breast cancer susceptibility locus on 16q12 with an unknown biological

196 e positional candidate for the schizophrenia-susceptibility locus on 1q22, although initial mutation

197 GWAS have identified a breast cancer susceptibility locus on 2q35.

198 report the discovery of a new endometriosis susceptibility locus on 4q12 (rs17773813[G], OR=1.28; P=

199 lymphocytic leukaemia (CLL) has identified a susceptibility locus on 6p25.3 associated with a modest

200 imity to the previously reported lung cancer susceptibility locus on 6q.

201 n 13q32 and support the presence of a second susceptibility locus on 8p21.

202 SCR inheritance, a genome scan reveals a new susceptibility locus on 9q31 exclusively in group II fam

203 Mice with the Sle3 lupus-susceptibility locus on a wild-type background were foun

204 likely due to a mutation in a major diabetes susceptibility locus on Chr 19, which interacts with add

205 Sle1 is a potent autoimmune susceptibility locus on chromosome 1 originally identifi

206 ndition in Europeans and implicating a novel susceptibility locus on chromosome 1.

207 and resistant (FVB/N ApoE0) mice revealed a susceptibility locus on chromosome 10 (11 cM, logarithm

208 reports, our data support evidence for a DN susceptibility locus on chromosome 10.

209 e independently identified a prostate cancer susceptibility locus on chromosome 10q11.2.

210 n by age at diagnosis highlighted a putative susceptibility locus on chromosome 11, among the later-o

211 ovide further evidence for a prostate cancer susceptibility locus on chromosome 15q and demonstrate t

212 ols of Japanese populations, we identified a susceptibility locus on chromosome 15q24.

213 s evidence for the IBD1 Crohn's disease (CD) susceptibility locus on chromosome 16 in several but not

214 A strands flanking a Multiple Sclerosis (MS) susceptibility locus on Chromosome 17q24.

215 revealed linkage to a previously unreported susceptibility locus on chromosome 18p11.

216 with FVBN mice mapped to an atherosclerosis susceptibility locus on chromosome 19 revealed in an int

217 y, the Piasy gene is localized in the PSORS6 susceptibility locus on chromosome 19p13, and Piasy nega

218 uggestive evidence for the presence of an AN-susceptibility locus on chromosome 1p.

219 young-onset (aged <45 years) type 2 diabetes susceptibility locus on chromosome 1q21-q23.

220 ts of previous studies for the presence of a susceptibility locus on chromosome 1q21-q25 (173.9 cM) a

221 A previous GWAS reported a possible TGCT susceptibility locus on chromosome 1q23 in the UCK2 gene

222 upporting the existence of a type 1 diabetes susceptibility locus on chromosome 1q42 and identify a c

223 significant evidence for an early-onset COPD-susceptibility locus on chromosome 2 and suggestive evid

224 lity 1 (Pas1) is the major mouse lung cancer susceptibility locus on chromosome 6.

225 nkage data reinforce the evidence of a major susceptibility locus on chromosome 6.

226 ded unambiguous evidence for a major disease susceptibility locus on chromosome 6p21 (PSORS1).

227 ings provide evidence for linkage to a novel susceptibility locus on chromosome 6p23.

228 from Sudan and Brazil identified a putative susceptibility locus on chromosome 6q27.

229 The putative autism-susceptibility locus on chromosome 7 may be the result o

230 American family showed evidence for a keloid susceptibility locus on chromosome 7p11 (maximal two-poi

231 nclusion, our data support a type 2 diabetes susceptibility locus on chromosome 8p that appears to be

232 re is evidence of linkage to a schizophrenia susceptibility locus on chromosome 8p21-22 found by seve

233 nalysis identified one novel significant RLS-susceptibility locus on chromosome 9p24-22 with a multip

234 (1) confirm the previously reported obesity-susceptibility locus on chromosomes 3, 7, and 17 and (2)

235 for NZB autoimmunity 2 (Nba2), a NZB-derived susceptibility locus on distal chromosome 1, produce aut

236 tudies uncovered a major atrial fibrillation susceptibility locus on human chromosome 4q25 in close p

237 idence in inbred mice and identified a major susceptibility locus on mouse chromosome 2 (rs27328255,

238 HIVAN and demonstrate a major renal disease susceptibility locus on mouse chromosome 3A1-3.

239 An NZM2410-derived lupus susceptibility locus on murine chromosome 4, Sle2(z), ha

240 Sle3 is an NZM2410-derived lupus susceptibility locus on murine chromosome 7.

241 ly inherited, but only one recessive genetic susceptibility locus, on chromosome 7p, has been identif

242 To map more precisely the susceptibility locus (or loci) within this broad region,

243 inkage disequilibrium with an unknown nearby susceptibility locus, or a direct maternal effect alone.

244 A second SNP tagged the PARK11 late-onset PD susceptibility locus (P=1.70 x 10(-5)).

245 genetic variation at CSMD1, a schizophrenia susceptibility locus, plays a role in the ratio between

246 Previous studies mapped one promotion susceptibility locus, Psl1, to distal chromosome 9.

247 viously recognized as containing a psoriasis susceptibility locus, PSORS5.

248 t lie within Idd (insulin-dependent diabetes susceptibility locus) regions, which are known to contai

249 s of 1,852 pedigrees, that a type 2 diabetes susceptibility locus resides on chromosome 20q.

250 A novel PD susceptibility locus, RIT2, on chromosome 18 (rs12456492

251 INTERPRETATION: We identified a novel PD susceptibility locus, RIT2, replicated several previousl

252 not only confirmed the association of a PrCa susceptibility locus, rs11672691 on chromosome 19, but a

253 de association study (GWAS) has identified a susceptibility locus (rs41270488) for HPV8 seropositivit

254 scovery of the first genome-wide significant susceptibility locus (rs4769613; P = 5.4 x 10(-11)) in 4

255 es of rheumatoid arthritis (RA) identified a susceptibility locus, rs874040(CC), which implicated the

256 ic mouse strains to map the major skin tumor susceptibility locus Skts1 within a genetic interval of

257 Ola)F1 backcrosses, to identify a skin tumor susceptibility locus, Skts14, on proximal chromosome 7.

258 or murine systemic lupus erythematosus (SLE) susceptibility locus Sle1 is syntenic to a chromosomal r

259 ematosus (SLE) modifiers yaa and lpr and the susceptibility locus Sle1.

260 or murine systemic lupus erythematosus (SLE) susceptibility locus, Sle1, corresponds to three loci in

261 e Pbx1 that corresponds to the NZM2410 lupus susceptibility locus Sle1a1.

262 J is prone to absence seizures, with a major susceptibility locus, spkw1, accounting for most of the

263 ith severe lung tissue damage mediated by TB-susceptibility locus sst1.

264 not yet provided convincing evidence for any susceptibility locus subject to parent-of-origin effects

265 The human IGRP gene maps to a diabetes susceptibility locus, suggesting that IGRP also may be a

266 of multiple sclerosis (MS) identified a new susceptibility locus tagged by a single nucleotide polym

267 nificant linkage of an oligogenic autoimmune susceptibility locus, termed AIS1, to a 14.4 cM interval

268 A major susceptibility locus, termed the Gvh1 locus, was identif

269 eptor 1 (CR1) is an Alzheimer's disease (AD) susceptibility locus that also influences AD-related tra

270 the risk variant in the PSORS1 [MIM 177900] susceptibility locus that confers the greatest risk for

271 e polymorphisms in lncRNAs, such as the 9p21 susceptibility locus that encodes the lncRNA antisense n

272 Sle2 is a lupus susceptibility locus that has been linked to glomerulone

273 Sle2c1 is an NZM2410- and NZB-derived lupus susceptibility locus that induces an expansion of the B1

274 , sex, and smoking status identified a novel susceptibility locus that mapped to a region of 18q12.3,

275 When we combine Tg7 with the Sle1 lupus susceptibility locus, the mice develop severe disease.

276 In addition to identifying a new melanoma-susceptibility locus, this is to our knowledge the first

277 for all phenotypes conferred by murine viral susceptibility locus Tmevp3.

278 e a mouse model based on the human psoriasis susceptibility locus TNIP1, also referred to as ABIN1, w

279 We mapped a previously unknown susceptibility locus to 2q37.1 and identified germline m

280 one large family of a presumptive strabismus susceptibility locus to 7p22.1 with a multipoint logarit

281 we have localized a potential hereditary PC-susceptibility locus to chromosome 1p36.

282 previous genome scan mapped a primary hip OA susceptibility locus to chromosome 2q with a maximum mul

283 icant evidence of linkage of a schizophrenia-susceptibility locus to markers on 13q32 and support the

284 were coupled to position a new hypertension-susceptibility locus, uncovering a previously unsuspecte

285 report a fine-mapping analysis of the 9q31.2 susceptibility locus using 43 160 cases and 42 600 contr

286 One novel significant susceptibility locus was detected for MI on chromosomal

287 The strongest evidence for an AMD susceptibility locus was found on chromosome 10q26 where

288 < 0.00002), the strongest evidence for an RA susceptibility locus was found on chromosome 16 (P = 0.0

289 cdkn2c gene encoding p18(INK4c) within a SLE susceptibility locus was found to account for reduced p1

290 lications compared with C57BL/6J, and a BALB susceptibility locus was mapped by linkage analysis to c

291 Linkage to a prostate cancer susceptibility locus was recently reported on chromosome

292 HeJ congenic mice in which the H2k purported susceptibility locus was replaced with the H2b purported

293 rbors the factor H gene (HF1/CFH), as an AMD susceptibility locus, we analyzed HF1 for genetic variat

294 To identify an additional RCC common susceptibility locus, we conducted a GWAS and performed

295 l dissection of the CD33 Alzheimer's disease susceptibility locus, we found that the rs3865444(C) ris

296 dence for significant association of a lupus susceptibility locus, which has been mapped to a chromos

297 Sle1a.1 is part of the Sle1 susceptibility locus, which has the strongest associatio

298 er to detect the gene underlying the disease-susceptibility locus, which hold regardless of the linka

299 he telomeric end of the NZM2410-derived Sle2 susceptibility locus, which we named Sle2c2.

300 For example, for a disease susceptibility locus with minor allele frequency of 15%,