ライフサイエンスコーパス: swine

1 ablishing long-term or chronic infections in swine.

2 were grown from core hepatic specimens from swine.

3 duced electrocardiographic asystole in large swine.

4 ave ablation of the lung was performed in 12 swine.

5 ere deployed via a catheter in the IVC of 11 swine.

6 morphology, and pulmonary hemodynamics in 10 swine.

7 arteries of 18 familial hypercholesterolemic swine.

8 the most economically significant viruses of swine.

9 nza A viruses (IAV) currently circulating in swine.

10 h acute respiratory failure and anesthetized swine.

11 e survival in the lower respiratory tract of swine.

12 he improvement of reproductive efficiency in swine.

13 torically contaminated soils fed to juvenile swine.

14 vesicular disease and neonatal mortality in swine.

15 A virus into Ohio and/or Indiana exhibition swine.

16 een used as growth promoters for poultry and swine.

17 rge, diverse viral reservoirs in poultry and swine.

18 ival in maximally immunologically mismatched swine.

19 ed ancestor viruses were identified in Asian swine.

20 tion of BICv in vitro and virus virulence in swine.

21 riant H3N2v cases associated with exhibition swine.

22 llance in areas with large concentrations of swine.

23 duced by cardiac catheterization of domestic swine.

24 lism for at least 5 weeks after placement in swine.

25 ersistence in the upper respiratory tract of swine.

26 use in controlling and preventing disease in swine.

27 When dosed systemically in swine, 13d provided a 15-fold enhanced CSF-to-plasma rat

28 -enhanced CT volume scans were acquired in 5 swine (40+/-10 kg) to generate CT angiography and perfus

29 METHODS AND Male Yorkshire Landrace cross swine (80.0 +/- 6.0 kg) underwent anesthesia, instrument

30 amily Bovidae shared the most pathogens with swine (82%).

31 In swine, a DT-CMR index of sheetlet reorientation (E2A) ch

32 es pose a potential risk to public health if swine-adapted viruses with H1N1pdm09 genes also have an

33 ell as a potential risk for public health if swine-adapted viruses with H1N1pdm09 genes have an incre

34 enetic diversity of H3N2 circulating in U.S. swine after 2009, with important implications for the co

35 t H3N2 genetic diversity circulating in U.S. swine after 2009.

36 response to adrenergic stimulation in obese swine after myocardial infarction.

37 an H9N2 strain three times in differentiated swine airway epithelial cells.

38 udorabies virus (PRV) is a broad host range, swine alpha herpesvirus that enters neuronal cells and u

39 were implanted in 58 coronary arteries of 23 swine and followed-up to 180 days.

40 tes, ascariasis still persists in commercial swine and has been designated a neglected disease of pov

41 arbonyl)amino)hexanoate (13d), was stable in swine and human plasma but liberated 14 in swine brain h

42 st that PCV3 commonly circulates within U.S. swine and may play an etiologic role in reproductive fai

43 ed into the spine and the uterine cavity, in swine and pregnant ovine models in vivo.

44 ly modified virus, we were able to vaccinate swine and protect them from developing ASF.

45 Influenza A viruses (IAVs) are endemic in swine and represent a public health risk.

46 orbable IVC filter can be safely deployed in swine and resorbs gradually over the 32-week testing per

47 red blood cells (RBC) isolated from knockout swine and to allogeneic or autologous human RBC.

48 ding the natural history of these viruses in swine and to selecting strains for effective vaccines.

49 no differences in the abilities of classical swine and TRIG swine viruses to exclude a second virus,

50 luenza A virus surveillance in US exhibition swine and whole-genome sequencing of 380 isolates, we de

51 tle and manure methane emissions for cattle, swine, and poultry for the contiguous United States.

52 tures of this platform in non-human primate, swine, and rodent models of deep brain stimulation (DBS)

53 nza outbreaks generally spread rapidly among swine, and the conventional methods for antigenic charac

54 ic CT perfusion technique was validated in a swine animal model.

55 ination inhibition (HI) data with monovalent swine antisera and antigenic cartography to evaluate the

56 ided the best support for cannulation of the swine aorta and vena cava.

57 Swine aortic arch endothelia exhibited elevated ROS, NOX

58 380 isolates, we demonstrate that exhibition swine are actively involved in the evolution of influenz

59 Feral swine are globally known as one of the most destructive

60 of swine IAVs.IMPORTANCE On a global scale, swine are one of the main reservoir species for influenz

61 flunixin, and sulfamethazine) in cattle and swine based on extensive published literature.

62 n swine and human plasma but liberated 14 in swine brain homogenate.

63 We performed a longitudinal field study in a swine breeding herd that presented with an outbreak of v

64 ing phylogenetic relationships among various swine breeds, Yorkshire and Landrace, are considered phe

65 Swine IAVs not only cause outbreaks among swine but also can be transmitted to humans, causing spo

66 Volume-overload HF was created in Yorkshire swine by inducing severe mitral regurgitation.

67 Cirrhosis was induced in swine by means of transcatheter infusion of ethanol and

68 c post-capillary PH was created in Yorkshire swine by partial pulmonary vein banding.

69 cardiomyopathy was created in 10 additional swine by subselective transcoronary ethanol administrati

70 Swine can harbor influenza viruses that are pathogenic t

71 ate recipients have been developed in mouse, swine, canine, and nonhuman primate models.

72 s influenza D virus (IDV), was identified in swine, cattle, sheep, and goats.

73 ficantly decreased ability to replicate in a swine cell line (SK6) and swine macrophage primary cell

74 sentery (SD) is a mucohemorrhagic colitis of swine classically caused by infection with the intestina

75 human influenza cases among individuals with swine contact.

76 Inflammatory sites in ACCT and MSC-treated swine contained immunotolerant CD3(+)/CD25(+)/FoxP3(+) r

77 l evolution of influenza A viruses infecting swine, contributing to the genetic and antigenic diversi

78 tran40 solution flushing was demonstrated in swine coronary arteries.

79 ge analysis, and myography, we show that the swine coronary artery endothelium generates discrete bas

80 cross-reactivity with other closely related swine coronaviruses, the N protein sequences of PEDV wer

81 ons proposing that SUCRAM supplementation of swine diet has potential for reducing meat contamination

82 ent of control strategies for this important swine disease.

83 Only 49% of currently listed OIE domestic swine diseases had published wild pig surveillance studi

84 ted 293 significant archaeological sites for swine disturbance across a vast area.

85 We found a 42% prevalence of swine disturbance among all sites, with prevalence not d

86 st a higher benefit of hyperoxia in comorbid swine due to an increased susceptibility to hemorrhagic

87 nces from isolates collected from exhibition swine during 2009 to 2013 to understand how the peak of

88 Swine dysentery (SD) is a mucohemorrhagic colitis of swi

89 ance on antimicrobial therapy for control of swine dysentery has been followed by reports of antimicr

90 wn to retain its ability to cause disease in swine, efficiently replicate in swine macrophage and tha

91 tometry showed that RBC from 2-gene knockout swine exhibited less human antibody binding than human b

92 al blood hematopoietic cells from transgenic swine expressing high or low levels of human CD47 were i

93 998-2016 using ORF5 sequences collected from swine farms in the Midwest region.

94 e of FRGs in the soils adjacent to the three swine farms where florfenicol was heavily used compared

95 e studied the resistome of Finnish dairy and swine farms where use of antibiotics is limited to treat

96 FRGs and the residue of florfenicol from six swine farms with the record of florfenicol usage.

97 In this study, we studied 5 swine farrow-to-wean farms for a year and characterized

98 ance and subsidence of different IAVs within swine farrow-to-wean farms over time, demonstrating that

99 The control of African swine fever (ASF) has been hampered by the unavailabilit

100 m day 10 postimmunization.IMPORTANCE African swine fever (ASF) is endemic in Africa, parts of the Tra

101 immune pigs developed signs of acute African swine fever (ASF).

102 native surveillance strategies for Classical Swine Fever (CSF) in wild boar and compared them with th

103 Classical swine fever (CSF) is a notifiable, highly contagious vir

104 Surveillance of Classical Swine Fever (CSF) should not only focus on livestock, bu

105 s (CSFV) is the causative agent of classical swine fever (CSF), a highly contagious viral disease end

106 s (CSFV) is the causative agent of classical swine fever (CSF), an economically important viral disea

107 Amazonia, coupled with expansion of African swine fever and possibly great economic losses.

108 African swine fever is a contagious and often lethal disease for

109 African swine fever is an acute hemorrhagic disease of pigs.

110 the usefulness of a dynamic network model of swine fever to predict pre-detection spread via movement

111 e linear DNA genome are found in the African swine fever virus (asfarvirus) and in the Phycodnavirida

112 African swine fever virus (ASFV) can cause highly lethal disease

113 ximately 165 proteins encoded by the African swine fever virus (ASFV) genome do not have significant

114 African swine fever virus (ASFV) infection is characterized by a

115 African swine fever virus (ASFV) is a highly pathogenic, double-

116 African swine fever virus (ASFV) is a macrophage-tropic virus re

117 African swine fever virus (ASFV) is the etiological agent of a c

118 The etiological agent, African swine fever virus (ASFV), is a highly structurally compl

119 t-and-mouth disease virus (FMDV) and African swine fever virus (ASFV).

120 2 sub-domains of two pestiviruses, classical swine fever virus (CSFV) and border disease virus (BDV),

121 Classical swine fever virus (CSFV) is the causative agent of class

122 Classical swine fever virus (CSFV) is the causative agent of class

123 role of MEK2 in the replication of classical swine fever virus (CSFV), a devastating porcine pestivir

124 the major envelope glycoprotein of classical swine fever virus (CSFV), is involved in several critica

125 assessed the benefits of adding the African swine fever virus NP868R capping enzyme during reovirus

126 African swine fever virus, a double-stranded DNA virus that infe

127 p or cluster of viruses encompassing African swine fever virus, faustovirus, pacmanvirus, and kaumoeb

128 that 31 genes are conserved between African swine fever virus, pacmanvirus, faustovirus, and kaumoeb

129 are caused by circulating strains of African swine fever virus.

130 mmercially available vaccine against African swine fever.

131 ired throughout the cardiac cycle in healthy swine, followed by in situ and ex vivo DT-CMR, then vali

132 were implanted in 99 coronary arteries of 37 swine for pharmacokinetics and healing evaluation at var

133 administered from below the filter in seven swine from 0 to 35 days after filter placement.

134 logenetic analysis of 368 IAV circulating in swine from 2009 to 2016 in the United States.

135 ing as a "swarm" of viruses were identified (swine H1-gamma, H1-beta, and H3-cluster-IV IAVs) and co-

136 culation in pigs of Eurasian avian-like (EA) swine H1N1 and 2009 pandemic (pdm/09) H1N1 viruses, reas

137 dy, we determined the 8 gene combinations of swine H3N2 IAV detected from 2009 to 2016.

138 Isolated perfused swine hearts were stained with di-4-ANEPPS and fiducial

139 sent a diagnostic investigation conducted in swine herds affected by vesicular disease and increased

140 ur Brachyspira species originating from U.S. swine herds and to investigate their associations with t

141 length polymorphism analysis of ITS revealed swine, human, and hybrid genotypes.

142 ely separate the viruses at two contemporary swine IAV antigenic clusters (H3N2 swine IAV-alpha and H

143 temporary swine IAV antigenic clusters (H3N2 swine IAV-alpha and H3N2 swine IAV-ss) with a sensitivit

144 enic clusters (H3N2 swine IAV-alpha and H3N2 swine IAV-ss) with a sensitivity of 84.9% and a specific

145 allowing H1N1pdm09 to reassort with endemic swine IAV.

146 interventions to reduce the transmission of swine IAVs and minimize the public health risk.

147 Antigenic characterizations of swine IAVs are key to understanding the natural history

148 lts demonstrated the molecular complexity of swine IAVs during natural infection of pigs in which nov

149 However, the epidemiology and diversity of swine IAVs is not completely understood.

150 Swine IAVs not only cause outbreaks among swine but also

151 regarding the diversity and distribution of swine IAVs on farrow-to-wean farms, where novel IAVs can

152 ited information on the genetic diversity of swine IAVs within farrow-to-wean farms, which is where m

153 identify antigenic variants of subtype H3N2 swine IAVs.

154 understand the diversity and epidemiology of swine IAVs.IMPORTANCE On a global scale, swine are one o

155 Genetic analysis highlighted that Italian swine IDVs are closely related to the D/swine/Oklahoma/1

156 ases have been children who had contact with swine in agricultural fairs.

157 The role of exhibition swine in influenza A virus transmission was recently dem

158 A viruses of the same genotype in exhibition swine in Ohio fairs sampled that year.

159 iridae family, was first reported in 2011 in swine in Oklahoma, and consequently found in cattle acro

160 ses that were introduced into North American swine in the mid-1990s, but they are antigenically disti

161 ly introduced into commercial and exhibition swine in the United States.

162 ght per group) and 28 in the livers of eight swine in vivo (seven per group).

163 between viruses cocirculating in exhibition swine increases viral diversity.

164 complexity of viral evolution in exhibition swine indicates that novel viruses are likely to continu

165 have resulted in enormous economic losses to swine industries worldwide.

166 breaks of the disease are devastating to the swine industry and are caused by circulating strains of

167 The US swine industry has been impaired over the last 25 years

168 onsistently low vulnerability of the British swine industry to large CSF outbreaks, we identified con

169 rn piglets, leading to massive losses to the swine industry worldwide during recent epidemics.

170 s, causing tremendous economic losses to the swine industry worldwide.

171 e most significant etiological agents in the swine industry worldwide.

172 ations in the control of this disease by the swine industry, as well as a potential risk for public h

173 implications for the control of IAV for the swine industry.

174 the costliest viral disease to ever face the swine industry.

175 s with a significant economic impact for the swine industry.

176 as significant economic consequences for the swine industry.

177 lCer generates protective immunity against a swine influenza (SI) virus infection when applied as an

178 In 2009, a swine influenza virus (pH1N1) jumped to humans and sprea

179 Swine influenza virus (SwIV) is one of the important zoo

180 ing a panel of 28 distinct human, avian, and swine influenza viruses, we found that only a small subs

181 l cells which is characteristic for virulent swine influenza viruses.

182 uenza A viruses in commercial and exhibition swine is central to assessing the risk for human infecti

183 uctural genes was constructed in a wild-type swine isolate and found to be negative for poly-N-acetyl

184 eltabps mutant was compared to the wild-type swine isolate for the ability to colonize and cause dise

185 in of B. bronchiseptica We hypothesized that swine isolates would also have the ability to form matur

186 3 glycan knockout (KO) pig cells and class I swine leukocyte antigens (SLA).

187 s were introduced into the HA of an isogenic swine lineage virus.

188 dazole (FBZ) and flunixin meglumine (FLU) in swine liver.

189 Twelve pairs of swine lungs were retrieved after cardiac arrest and stud

190 e disease in swine, efficiently replicate in swine macrophage and that is fluorescently tagged.

191 to replicate in a swine cell line (SK6) and swine macrophage primary cell cultures.

192 condition was applied in the pretreatment of swine manure, and the effect of the pretreatment on anae

193 ternative process for effective treatment of swine manure.

194 chnique was retrospectively validated in six swine (mean weight, 37.3 kg +/- 7.5 [standard deviation]

195 (<4 days) took place with the development of swine MHC-specific cytotoxic alloantibody.

196 events the development of heart failure in a swine MI model.

197 swine/Pennsylvania/2436/2012 (pH1N1-1) and A/swine/Minnesota/2499/2012 (pH1N1-2) viruses.

198 ruses A/Ann Arbor/6/1960 (H2N2) (AA60) and A/swine/MO/4296424/06 (H2N3) (Sw06).

199 technique was retrospectively validated in a swine model and has the potential to be used for accurat

200 nd left ventricular functional recovery in a swine model of chronic ischemic cardiomyopathy without a

201 nal angiogenesis in RVD using an established swine model of chronic RVD.

202 In the familial hypercholesterolemic swine model of femoral restenosis, the implantation of a

203 esponse in the familial hypercholesterolemic swine model of femoral restenosis.

204 We recently demonstrated in a swine model of ischemia-reperfusion (IR) that hyperchole

205 also confirmed in a more clinically relevant swine model of skin.

206 solution for extended lung preservation in a swine model using OCS Lung.

207 lly deployed in the curved blood vessel of a swine model without any significant complications or abn

208 ntions is technically feasible and safe in a swine model, and potentially, in humans.

209 In the swine model, lung collapse and intratidal recruitment/de

210 erventions by using a phantom and an in vivo swine model.

211 orbable inferior vena cava (IVC) filter in a swine model.

212 LA structural remodeling in experimental MI swine models recapitulating the effects of left ventricu

213 human antibody binding to donor tissues from swine must approximate the antibody binding occurring in

214 In 15 swine, myocardial infarction was induced by left anterio

215 dial injection to immunosuppressed Yorkshire swine (n = 29) 2 weeks after MI.

216 lian swine IDVs are closely related to the D/swine/Oklahoma/1334/2011 cluster.

217 influenza-like illnesses (ILIs) and licensed swine operations from 2008 to 2012 in North Carolina.

218 models to correlate the number of permitted swine operations per county with the weeks of onset and

219 ionship between ILI onset week and number of swine operations.

220 isolated from various genetically engineered swine or from humans.

221 s study, we examined human and swine sera by swine or human TTV-specific PCRs, to determine whether s

222 In 2009, a swine-origin H1N1 IAV (pH1N1) was transmitted to humans,

223 Recent outbreaks of swine-origin influenza A(H3N2) variant (H3N2v) viruses h

224 Streptococcus suis is a zoonotic swine pathogen and a major public health concern in Asia

225 We identified 34 (87%) OIE listed swine pathogens that cause clinical disease in livestock

226 compared to that of the highly homologous A/swine/Pennsylvania/2436/2012 (pH1N1-1) and A/swine/Minne

227 Swine play a key role in the ecology and transmission of

228 uired to become virulent for pigs.IMPORTANCE Swine play an important role in the interspecies transmi

229 Influenza A(H1N1) viruses entered the U.S. swine population following the 1918 pandemic and remaine

230 2 viruses that were introduced into the U.S. swine population in the mid-1990s, but they are differen

231 a A viruses (IAVs) are circulating among the swine population, playing an important role in influenza

232 Bordetella bronchiseptica is pervasive in swine populations and plays multiple roles in respirator

233 ction of influenza A viruses from commercial swine populations provides new genetic diversity in exhi

234 In 2013, U.S. swine producers were confronted with the disruptive emer

235 ASF, a transboundary disease that threatens swine production world-wide.

236 Xenoantigenicity of swine RBC can be eliminated via gene disruption.

237 reduce the levels human antibody binding to swine RBC that is as low as autologous human RBC.

238 k, owing to an expansion of IAV diversity in swine resulting from long-distance live swine trade.

239 Feral swine rooting commonly exceeds 20 cm in depth, especiall

240 In this study, we examined human and swine sera by swine or human TTV-specific PCRs, to deter

241 Serological tests were conducted on 3698 swine sera, including archive sera collected in 2009, as

242 ity of genotypes cocirculating in exhibition swine since 2013 could facilitate the evolution of new r

243 ding to markedly prolonged survival of donor swine skin xenografts that may be applicable to clinical

244 f the monocyte-macrophage lineage, affecting swine species and provoking severe economic losses and h

245 During in-vivo swine studies (n = 6), 12-lead ECG signals were recorded

246 Route of delivery was analyzed in AMI swine studies and clinical trials (6 clinical trials; n=

247 odulating the efficacy of MSC therapy in AMI swine studies and clinical trials, suggesting the superi

248 In AMI swine studies, transendocardial stem cell injection redu

249 able tool to conduct pathogenesis studies in swine, study on virus-macrophage interaction and to run

250 Both mechanisms fail in CFTR(-/-) swine, suggesting that cystic fibrosis airways do not re

251 We show in swine that IgL rearrangements precede IgH gene rearrange

252 to the pathogenesis of B. bronchiseptica in swine, the KM22Deltabps mutant was compared to the wild-

253 es and did not affect disease progression in swine, the natural host for ASFV.

254 When administered intramuscularly (i.m.) to swine, there was no induction of disease, even at high d

255 ome sequences from IAVs collected in Mexican swine to establish that the swine virus responsible for

256 ted pigs suggest that it may be possible for swine to serve as a reservoir for prion disease under na

257 The potential for swine to serve as hosts for the agent of CWD is unknown.

258 udy was to investigate the susceptibility of swine to the CWD agent following experimental oral or in

259 y in swine resulting from long-distance live swine trade.

260 Swine treated with endothelial cell therapy showed mean

261 Recently it was found that swine TTV's (TTSuVs) can act as primary pathogens.

262 uman TTV-specific PCRs, to determine whether swine TTVs (TTSuV) DNA can be detected in humans and vic

263 Healthy swine underwent endocardial and epicardial linear ablati

264 METHODS AND Female Gottingen swine underwent left anterior descending coronary artery

265 Massachusetts General Hospital miniature swine underwent occlusion of the midleft anterior descen

266 c acid was injected into the myocardium of 8 swine using MRI-conspicuous needle catheters.

267 lic brain of propofol-anaesthetized juvenile swine using subdural electrode strips (electrocorticogra

268 wine viruses of the pandemic H1N1 lineage, A/swine/Virginia/1814-1/2012 (pH1N1low-1) and A/swine/Virg

269 wine/Virginia/1814-1/2012 (pH1N1low-1) and A/swine/Virginia/1814-2/2012 (pH1N1low-2), with almost und

270 Nevertheless, the classical swine virus also showed the ability to reassort, suggest

271 ected in Mexican swine to establish that the swine virus responsible for the 2009 pandemic evolved in

272 bility to reassort compared to the classical swine virus.

273 The reassortment with endemic swine viruses and maintenance of some of the H1N1pdm09 i

274 However, no related swine viruses have been detected in Mexico or any part o

275 We recently characterized two swine viruses of the pandemic H1N1 lineage, A/swine/Virg

276 dm09 is also highly adapted to humans, these swine viruses pose a potential risk to public health if

277 in the abilities of classical swine and TRIG swine viruses to exclude a second virus, suggesting that

278 d TX/96 infection was fully excluded by both swine viruses.

279 fferent epidemiologies of TRIG and classical swine viruses.

280 eassortment capacities of classical and TRIG swine viruses.

281 After 3 min of arrest, swine were allocated to one of three (1) REBOA plus 4 un

282 Swine were assessed by cardiac magnetic resonance imagin

283 traportal delivery of endothelial cells, the swine were euthanized and the explanted liver underwent

284 kin grafts from the hematopoietic cell donor swine were placed on recipients 5 weeks after the last c

285 tricular fibrillation, 16 female 3-month-old swine were randomized to 1) blood pressure care: titrati

286 hree weeks after induction of cirrhosis, the swine were randomly assigned to receive autologous cell

287 Obese Ossabaw swine were subjected to gradually developing regional co

288 tifiable, highly contagious viral disease of swine which results in severe welfare and economic conse

289 ical studies (58 studies; n=1165 mouse, rat, swine) which revealed a reduction in infarct size and im

290 ical studies (58 studies; n=1165 mouse, rat, swine) which revealed a reduction in infarct size and im

291 Eight 50 kg Yorkshire swine with a femoral artery catheter for blood pressure

292 in vitro); intact, large animal models (eg, swine with chronic coronary stenosis); as well as human

293 stories in hypothetical populations of feral swine with different contact structures (homogenous, met

294 Gottingen swine with experimental ischemic cardiomyopathy were ran

295 In swine with healed infarction, the total area of low bipo

296 ring resuscitation from hemorrhagic shock in swine with preexisting coronary artery disease reduced r

297 ring resuscitation from hemorrhagic shock in swine with preexisting coronary artery disease.

298 nfectivity.IMPORTANCE We challenged domestic swine with the chronic wasting disease agent by inoculat

299 line was technically successful in all eight swine, with no complications.

300 ic pathogen that causes Glasser's disease in swine, with polyserositis, meningitis, and arthritis.

301 mplications for vaccine strategies targeting swine workers, as well as virologic surveillance in area