ライフサイエンスコーパス: swine influenza

1 s sporadic infection with triple-reassortant swine influenza A (H1) viruses in persons with exposure

2 infection of humans with triple-reassortant swine influenza A (H1) viruses reported to the Centers f

3 Triple-reassortant swine influenza A (H1) viruses--containing genes from av

4 o prevent an influenza epidemic from another swine influenza A H1N1 recombinant virus.

5 After a new reassortant swine influenza A H1N1 virus caused outbreaks in Mexico

6 pin-enhanced DFA detected 230 (84.6%) of 272 swine influenza A PCR-positive results overall but 25 (9

7 immune responses and the major component in swine influenza A vaccines.

8 Control of swine influenza A virus (IAV) in the United States is hi

9 luate the efficacy of commercial inactivated swine influenza A virus (IAV) vaccines and experimental

10 Swine influenza A virus is an endemic and economically i

11 Swine influenza A viruses (IAV) are a major cause of res

12 additional 1,404 whole-genome sequences from swine influenza A viruses collected globally during 1931

13 s are evidently more resistant to avian than swine influenza A viruses, mediated in part through fron

14 cific for the detection of human, avian, and swine influenza A viruses.

15 s are higher than those of human and classic swine influenza A viruses.

16 ed to assess persistence of antibody against swine influenza A/H1N1(2009) pandemic influenza, childre

17 am began in January 1976 with an outbreak of swine influenza among trainees at Ft. Dix, New Jersey.

18 rigins of the pandemic virus and the classic swine influenza and (postpandemic) seasonal H1N1 lineage

19 69 ferrets infected with seasonal influenza, swine influenza, and highly pathogenic avian influenza (

20 Concern that pandemic H1N1 swine influenza could be transmitted by solid organ tran

21 ecobiological association between human and swine influenza could extend to before 1918.

22 918, but an anecdotal report suggests that a swine-influenza epizootic might have occurred in England

23 gin reassortant containing human, avian, and swine influenza genes.

24 A/New Caledonia/20/99 [Ncal99]), a classical swine influenza H1N1 virus isolate (A/Swine/Iowa/15/30 [

25 lowing in vitro infection with 2009 pandemic swine influenza (H1N1/09).

26 Swine influenza has been recognised only since 1918, but

27 The Swine Influenza Immunization Program began in January 19

28 Drawing from the ill-fated swine influenza immunization program of 1976, this artic

29 By contrast with the recent documentation of swine influenza, influenza in horses has been well docum

30 Swine influenza is a highly contagious zoonotic disease

31 Swine influenza is an acute respiratory disease caused b

32 lly poorly transmitted between humans, while swine influenza is better transmitted due to glycan simi

33 Control of swine influenza is primarily through the vaccination of

34 2009 virus was derived from well-established swine influenza lineages; however, there is no convincin

35 ity to pandemic H1N1 hemagglutinin after the swine influenza pandemic of 2009 in pooled human polyclo

36 luenza A virus strains, such as the new H1N1 swine influenza, represents a serious threat to global h

37 lCer generates protective immunity against a swine influenza (SI) virus infection when applied as an

38 In 1976, the national swine influenza vaccination program in the United States

39 drome (GBS) occurred among recipients of the swine influenza vaccine in 1976-1977.

40 e (GBS) following administration of the 1976 swine influenza vaccine led to a heightened focus on GBS

41 Vaccination with the A/New Jersey/1976 swine influenza vaccine substantially boosted cross-reac

42 ain-Barre Syndrome (GBS) found with the 1976 swine influenza vaccine, both active surveillance and en

43 tantially lower than that seen with the 1976 swine influenza vaccine.

44 GBS has also been associated with the 1976 swine-influenza vaccine.

45 were vaccinated with recent seasonal or 1976 swine influenza vaccines.

46 lb09]), with that of the 1918-like classical swine influenza virus (A/swine/Iowa/1930 [IA30]) in the

47 In 2009, a swine influenza virus (pH1N1) jumped to humans and sprea

48 Swine influenza virus (SIV) H3N2 with triple reassorted

49 1-F2 protein of triple-reassortant (TR) H3N2 swine influenza virus (SIV) in pigs and turkeys.

50 raction between Mycoplasma hyopneumoniae and swine influenza virus (SIV) in the induction of pneumoni

51 dentifying a student with triple-reassortant swine influenza virus (SIV) infection and pig exposure a

52 ole of the NS1 protein in the virulence of a swine influenza virus (SIV) isolate in pigs by using rev

53 ation of a so-called triple reassortant (TR) swine influenza virus (SIV).

54 Swine influenza virus (SwIV) is one of the important zoo

55 As a positive control, an H3N2 swine influenza virus A was used.

56 y shown to enhance the replication of a 1976 swine influenza virus also significantly improved the re

57 Novel triple-reassortant H3N2 swine influenza virus emerged in 1998 and spread rapidly

58 n that infection in humans with the pandemic swine influenza virus induces antibodies with specificit

59 Before 1998, swine influenza virus isolates in the United States were

60 recursor strains from the triple-reassortant swine influenza virus lineage, which cause only sporadic

61 , and nonstructural genes being of classical swine influenza virus origin, and the PA and PB2 polymer

62 The recent flu epidemic caused by an H1N1 swine influenza virus presents an opportunity to examine

63 Biosystems 7500 Fast platform, using the CDC swine influenza virus real-time RT-PCR detection panel (

64 in A/New Caledonia/20/1999 and 2009 pandemic swine influenza virus strain A/California/04/2009.

65 rotected completely against lethal avian and swine influenza virus strains in mice, and induced robus

66 to a representative human triple-reassortant swine influenza virus that has circulated in pigs in the

67 ls which recovered from exposure to virulent swine influenza virus were completely resistant to infec

68 th the reconstructed 1918 virus, a 1976 H1N1 swine influenza virus, and a highly pathogenic H5N1 viru

69 CD8(+) T-cell epitopes in NP of human versus swine influenza virus, consistent with the idea that the

70 Therefore, we chose a H1N1 swine influenza virus, Sw/OH/24366/07 (SwIV), which has

71 Unlike classical swine influenza virus, TR SIV produces a full-length PB1

72 onstrate here that an engineered reassortant swine influenza virus, with the same gene constellation

73 We report that swine influenza virus-like substitutions T200A and E227A

74 A new H1N1 triple-reassortant "swine" influenza virus was recently described in individ

75 e its absence from some animal (particularly swine) influenza virus isolates, variable expression in

76 Swine influenza viruses (SIV) have been shown to sporadi

77 Swine influenza viruses (SIV) naturally infect pigs and

78 Triple reassortant swine influenza viruses (SIVs) and 2009 pandemic H1N1 (p

79 Since the introduction of H3N2 swine influenza viruses (SIVs) into U.S. swine in 1998,

80 We identified 34 swine influenza viruses (termed rH3N2p) with the same co

81 logic factors that limit the transmission of swine influenza viruses between humans are unresolved.

82 large-scale genomic characterization of 290 swine influenza viruses collected from 14 European count

83 ttle known about the host barriers that keep swine influenza viruses from entering the human populati

84 se data highlight the increased diversity of swine influenza viruses in the United States and would i

85 fluenza subtypes by mixing avian, human, and swine influenza viruses is possible.

86 Due to their attenuation, NS1-mutated swine influenza viruses might have a great potential as

87 e epitopes in parallel lineages of human and swine influenza viruses that have been diverging since r

88 Here we use comparisons of human and swine influenza viruses to rigorously demonstrate that h

89 y (typically found in avian and classic H1N1 swine influenza viruses), conferring binding to human- a

90 uman H1N1 influenza A virus strains, several swine influenza viruses, and influenza B viruses but wer

91 uenza viruses, unlike other human, avian and swine influenza viruses, are resistant to the antiviral

92 nes can be recombined from human, avian, and swine influenza viruses, leading to triple reassortants.

93 However, when transferred into avian and swine influenza viruses, only partial ts and attenuation

94 ing a panel of 28 distinct human, avian, and swine influenza viruses, we found that only a small subs

95 ses--containing genes from avian, human, and swine influenza viruses--emerged and became enzootic amo

96 l cells which is characteristic for virulent swine influenza viruses.

97 modon hispidus) are susceptible to avian and swine influenza viruses.

98 nd might reassort with currently circulating swine influenza viruses.

99 es and antigenically distinct from reference swine influenza viruses.

100 understanding of the antigenic diversity of swine influenza will facilitate a rational approach for