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1 liquid gating, thereby forming a nonvolatile switch.
2 st density dependence to the lytic-lysogenic switch.
3 es during reversals akin to a spatial toggle switch.
4 had a manic switch or was hospitalized for a switch.
5 genesis or to trigger the tumoral angiogenic switch.
6 rol group and were completely resolved after switch.
7 f IF2 drive and regulate this conformational switch.
8 ructure of the prism faces accounts for this switch.
9 the role of miR-125a-5p in VSMCs phenotypic switch.
10 rain inputs activating the MLR like a dimmer switch.
11 inetics and energetics of the conformational switch.
12 rom increased cognitive load during language switches.
13 mental speed limit of the current electronic switches.
14 and subsequent bypass by error-free template switching.
15 es similarly to many types of effortful task switching.
16 ng logic gates through incoherent spintronic switching.
17 s to control food-regulated behavioral state switching.
18 mammals, enabling damage bypass by template switching.
19 which undergoes solvent-triggered tautomeric switching.
20 which revealed multiple episodes of capsular switching.
21 eries have suggested beneficial effects from switching.
22 switch, and then we discuss how this toggle switch accounts for the abrupt and irreversible nature o
23 atically revealed the behaviours of a toggle switch across scales from single-cell dynamics to popula
24 Ampaphos ligand triggers a regioselectivity switch, allowing both linear and branched isomers to be
25 the complex form, a conformation for domain switching, allows FIN219 to switch to its high-affinity
28 evaluated clinical benefit from early taxane switch and circulating tumor cell (CTC) biomarkers to in
32 points in the time-series, characterize the switches and filter the results with user input paramete
37 o signals in the manner of a bistable toggle switch, and then we discuss how this toggle switch accou
38 ublications indicating problems with generic switches, and complaints to the US Food and Drug Adminis
40 evolutionary implications of symbiont gains, switches, and replacements, and identify future research
41 onal single-molecule devices such as diodes, switches, and wires are well studied, complex single-mol
42 ors, different modalities and definitions of switching, and available literature and recommendations
45 ayed accumulation of virus-specific, isotype-switched ASC requires CD19-dependent GC formation in CLN
50 ich are Cdc42, Rac1, and RhoA, are molecular switches best known for regulating the actin cytoskeleto
51 w a polymer composed of a single protein can switch between different supercoiled states with high co
52 totrophs such as Rhodobacter sphaeroides can switch between heterotrophic and photosynthetic growth.
56 a as a major neural substrate regulating the switch between positive and negative affective states, w
59 tivation is not analogous to a simple binary switch between two defined conformations, but the activa
60 ean network modelling identifies a mandatory switch between two stable states (stem and differentiate
61 al sensorimotor area while monkeys naturally switched between exploring and exploiting rewarding opti
62 a result, 45%, 49%, and 50% of all subjects switched between tertiles of sodium intake when the 1-,
63 with intestinal bacteria in mice undergoing switches between high-fat, high-sugar (HFHSD) and low-fa
64 food availability controls behavioral state switching between active (roaming) and sedentary (dwelli
66 ultiplexed cell culture system, we find that switching between certain combinations of antibiotics co
68 k agents, characterized by a higher level of switching between different social activities than expec
72 geometries during the lifetime of a complex, switching between states of opposing prochirality in the
73 are approximately a factor of 10 different, switching between the different images modes may be done
75 beads at low stiffness of restraint revealed switching between two states: frictional coupling to ret
76 first implements the G-quadruplex structure-switching biosensing principle in graphene nanoelectroni
78 tion vectors decorrelated rapidly after each switch, but did not develop anticorrelated firing patter
79 APA site usage frequencies of 42 genes were switched by auxin, suggesting that auxin affects the cho
80 method to predict potential phosphorylation switches by mapping phosphorylation sites to protein-pro
81 fectors YAP/TAZ act as on-off mechanosensing switches by sensing modifications in extracellular matri
85 gle CLCb-expressing NSCLC cells, as well as "switched" cells that predominantly express CLCb, exhibit
86 ng the filament to the atomic scale, current switching characteristics are observed that are distinct
88 hway that involves ERF74 acting as an on-off switch controlling an RbohD-dependent mechanism in respo
91 tatory-to-inhibitory gamma-aminobutyric acid switch; defects in this switch have been unequivocally l
95 Persistent currents in non-molecular rings switch direction as a function of the magnetic flux pass
96 are clearly observed when the magnetization switches direction in the GaMnAs layer, but are negligib
100 resents a multistable, epigenetic anatomical switch: experimental reversals of bioelectric state rese
101 orectal cancer cells, as well as a metabolic switch favoring glutamine consumption through IGF1 recep
102 /- 220 mum at baseline to 419 +/- 212 mum at switch follow-up (p = 0.86), but decreased significantly
104 rent EPFs, thus functioning as a specificity switch for the regulation of the activities of ERfs.
107 c chemostat cultures to demonstrate that the switch from aerobic to anaerobic metabolism is brought a
109 ons are predisposed to an activity-dependent switch from GABA-mediated inhibition to excitation.
111 n ring aromaticity/antiaromaticity, with the switch from ground-state singlet ions to triplet-favored
112 also be the result of an age-related subunit switch from high affinity beta2-containing nAChRs to low
113 s whereby IL-13Ralpha2 serves as a molecular switch from invasion to proliferation, and suggest that
114 Previous studies suggested that the KSHV switch from latency to lytic replication is primarily co
116 liest stages of plant development and on the switch from pluripotency to differentiation in different
117 lates STAT3 and TBK1 signaling, triggering a switch from proinflammatory to anti-inflammatory respons
118 he authors show that beta-cells in zebrafish switch from proliferative to functional states with incr
120 role in biofilm development by enabling the switch from the planktonic to the biofilm mode of growth
121 In many ways, the experience with the global switch from trivalent OPV (tOPV) to bivalent OPV (bOPV)
122 n stimulus, the tweezers can be mechanically switched from an open "W"-shaped conformation to a close
123 harmful nanoparticles by a third, as drivers switched from ethanol to cheaper gasoline, showing a ben
126 ctivity, an increase in current density when switching from a Ca(2+)-containing solution to a divalen
128 n adenine dinucleotide(FAD), and prompts VVD switching from Dark state to Light state with significan
129 o CPPase, with product selectivity gradually switching from FPP to GPP, until replacement of the fina
130 We aimed to assess glycaemic outcomes when switching from multiple daily injections (MDI) to CSII i
131 ctance difference of 7.3 is observed for the switching from the highest conducting state to second-hi
133 s therapeutic targets due to their molecular switch function in turning gene expression on or off and
134 lso show that optix simultaneously acts as a switch gene for blue structural iridescence in some butt
135 embrane-bound glycolytic enzymes and in turn switches glucose flux towards glycolysis relative to the
136 ring enzyme 1alpha (IRE1alpha) as a critical switch governing M1-M2 macrophage polarization and energ
138 ht, so-called all-optical helicity dependent switching, has renewed interest in the physics that gove
139 ma-aminobutyric acid switch; defects in this switch have been unequivocally linked to diseases such a
144 ults suggests that UBP684 binding may induce switch in conformation similar to glutamate LBD locked s
145 reporter to directly monitor the phenotypic switch in drug-resistant bacteria with temporal resoluti
147 1 proteins of S. pyogenes show a dichotomous switch in ligand binding between human tissue and blood
149 yte-enriched microRNA-211, a known metabolic switch in nonpigmented melanoma cells, was severely down
150 f, soft, or suspension, induced a phenotypic switch in prostate cancer cells via mechanotransduction.
151 ch a mechanotransduction-mediated phenotypic switch in prostate cancer cells was accompanied by decre
153 ence, dopamine signalling mediates an energy switch in the mushroom body that controls long-term memo
157 ferroelectric polarization and polarization switching in prototypical BaTiO3 of tetragonal symmetry.
160 r invariant natural killer T (iNKT) cells in switching inflammation to tissue repair in an interlukin
161 odel of aromatic amino acid side chains) can switch inherent dynamical tendencies for competing modes
163 ur theoretical calculations suggest that the switch is due to the change in the energy level alignmen
171 k, operating on a longer time scale, changes switch-like behavior into oscillations having a period o
173 S, which leads to bistability and allows for switch-like responses to inputs, is nested within a nega
175 een in topologically associating domains, as switching markedly favors local (short-range) contacts o
178 controls revealed that frequencies of class-switched memory B cells were increased in the patients,
179 These methods reveal that conformational switches modulate normal and abnormal information transf
182 n different states and that a conformational switch of aromatic side-chains fine-tunes sequence speci
184 st that, by regulating DCC, miR-218 may be a switch of susceptibility versus resilience to stress-rel
185 tients with compartmental samples, whereas a switch of the major HCMV population was observed in 6 in
187 significant expansion, retention, and class-switching of autoreactive B cells in GCs under condition
192 dal analysis leads to discovery of a general switching of polyhedral distortions at symmetry-disallow
193 sequence-specific oligomer synthesis and the switching of product chirality, a photo-responsive host
194 system genes in the same operon ensures that switching of tetrapyrrole metabolism toward bacteriochlo
195 ed and reduced states, leading to reversible switching of the DNA conductance between two discrete le
197 When <10 rewarded trials separated goal switches, OFC population vectors decorrelated rapidly af
198 alpha-methylisoserine-derived sulfamidates, switching off and on the nucleophilic ring-opening in a
199 uminescence would be better interpreted as a switching off of the promoter, or where an increase in b
200 d (2) switching on the expression of PYY and switching off the expression of certain other hormones i
201 st importantly, the computational ability to switch on and off hydrogen bonds permitted us to identif
202 ntiating into enteroendocrine cells, and (2) switching on the expression of PYY and switching off the
203 cular smooth muscle cells (VSMCs) phenotypic switch, one of the main events responsible for bare meta
204 lidean lattice in particular, hysteresis and switching only occur in an extremely narrow region of th
205 20% were atrial baffling procedures (atrial switch operation) or 2-stage repairs (pulmonary artery b
212 steps of TSIS are to search for the isoform switch points in the time-series, characterize the switc
213 e broken) statistical system and uncover how switching policy affects oscillatory trends and the spee
214 inal dynorphin/KOR signaling, functions as a switch, preventing or promoting, respectively, spinal EM
218 ed to exhibit very clean on/off fluorescence switching properties for polar volatile organic compound
220 16-residue "target region" of the flagellar switch protein, FliM, leads to easily measurable changes
221 at PufQ governs the haem/bacteriochlorophyll switch; pufQ is found within the oxygen-regulated pufQBA
224 to two orders of magnitude higher resistance-switching ratio at 300 K, which is attributed to the int
225 ytidine deaminase (AID) initiates both class switch recombination (CSR) and somatic hypermutation (SH
228 We find that AhR negatively regulates class-switch recombination ex vivo by altering activation-indu
230 rates mimicking the mammalian immunoglobulin switch regions are particularly good AID substrates in v
233 an visual acuity over the 3 months after the switching rules were met, although all patients continue
240 hybrid transcription factor SS18:SSX alters SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin remod
241 Visible-light-responsive reversible color-switching systems are attractive to many applications be
244 plays a key role in controlling a molecular switch that dictates cell fate following exposure to adv
246 dy reveals a GbetaL-ubiquitination-dependent switch that fine-tunes the dynamic organization and acti
247 rain sites under the control of a PBel(CGRP) switch that is necessary to arouse animals from hypercap
249 mediated dephosphorylation provide a phospho-switch that regulates the cellular activity of ATG4B to
250 angl2-Dvl interaction as a key bi-functional switch that underlies the central logic of PCP signaling
251 rae biofilm formation, as RbmA variants with switches that are locked in either of the two states lea
252 ling elicits context-dependent transcription switches that determine normal development and oncogenes
253 Moriarty et al. now suggest that the pH switching that occurs between different cellular environ
255 emical (EC) gate voltage to the molecule, we switch the redox group between the oxidized and reduced
256 dimers bind to a myriad of genomic sites and switch the targeted genes on or off with precision.
258 c responses are dynamically controllable via switching the folding state of Miura-ori split-ring reso
260 ng the participants who met the criteria for switching, the CATT participants were a mean (SD) of 79.
261 nesis to produce astroglia and interneurons, switch their fate and generate granule neurons in mice.
262 ypic plasticity, as they have the ability to switch their functional phenotypes during inflammation a
263 d to a reduced foraging payoff, 49% of birds switched their behavior to a higher-payoff foraging tech
264 al, we demonstrate that matrix degradability switches three-dimensional endothelial cell invasion bet
265 be reinforced by the elevated costs of prey switching, thus promoting the process of resource specia
266 intensity at 355 nm tune the characteristic switching time over several orders of magnitude, from le
267 6 weeks, 1 hospital was randomly assigned to switch to "HEART care," during which physicians calculat
270 Patients who were economically motivated to switch to clopidogrel had (compared with patients who co
271 Flint is located) was directly linked to the switch to corrosive Flint River water from noncorrosive
273 ation for domain switching, allows FIN219 to switch to its high-affinity mode and thereby enhances JA
275 ontinue risperidone for 16 weeks followed by switch to placebo for 16 weeks, or to receive placebo fo
277 atio [HR] 2.6, 95% CI 2.5-2.8; p<0.0001) and switch to second-line ART (HR 5.2, 4.4-6.1; p<0.0001]) c
278 Patients were randomly assigned (2:1) to switch to the open-label study regimen or continue the c
279 set, 2 of 9 (22.2%) ERBB2/HER2-negative BrCa switched to ERBB2/HER2-positive with 1 BrM acquiring ERB
280 of the 35 patients in ACOSOG Z1031B who were switched to neoadjuvant chemotherapy experienced a pCR (
281 lacebo [62%, including early escape patients switched to sirukumab at week 18] of 294; 194 [66%] of 2
285 We investigated the efficacy and safety of switching to a single-tablet regimen of darunavir, cobic
286 studies have established that a strategy of switching to an aromatase inhibitor after 2 to 3 years o
287 conversion, no association was found between switching to an employment model and improvement in any
291 te the efficacy, safety, and tolerability of switching to this regimen compared with remaining on cof
292 t nitrate induces PGC1alpha expression and a switch toward type I and IIa fibers in rat muscle and my
293 mines language control networks' engagement: switching under external constraints heavily recruited p
294 Our results indicate that the benefits of switching virologically suppressed NVP-exposed HIV-infec
297 y networks that control this differentiation switch, we employed a high-throughput microfluidic imagi
299 icular, the C terminus functions as a toggle switch, which affects access of the NADPH substrate to t
300 Moreover, Coop-seq uncovers a nucleotide switch within the POU half-site when spacing is altered,
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