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1 ed the enhancement of PA learning and silent synapse formation.
2 ntified two new genes involved in electrical-synapse formation.
3 sites, where it promotes dendritic spine and synapse formation.
4 is required for both electrical and chemical synapse formation.
5 contact the plasma membrane directly during synapse formation.
6 gions, stimulate axonal pruning, and inhibit synapse formation.
7 es drive polarity in both cell migration and synapse formation.
8 onset of remodeling and are critical for new synapse formation.
9 instructive role of intrinsic mechanisms in synapse formation.
10 on during fever contributes to immunological synapse formation.
11 dNK, and may represent the initial stage of synapse formation.
12 cytoskeleton to regulate neuronal growth and synapse formation.
13 without changing neuronal differentiation or synapse formation.
14 neuronal differentiation, axon guidance and synapse formation.
15 D1; postsynaptic) were explored for chemical synapse formation.
16 anism distinct from conventional virological synapse formation.
17 esting that Tim-3 plays a functional role in synapse formation.
18 ule play a key role in the efficiency of the synapse formation.
19 s suggest that each plays a distinct role in synapse formation.
20 promote neuronal ion channel maturation and synapse formation.
21 l changes that initiate spine and excitatory synapse formation.
22 d throughout the periphery of T-cells during synapse formation.
23 , forming trans-synaptic triads that promote synapse formation.
24 additional ligands to orchestrate excitatory synapse formation.
25 ntial role in modulating neuronal growth and synapse formation.
26 e neuronal surface and impaired heterologous synapse formation.
27 motility, and promotes stable immunological synapse formation.
28 ion and its role in dendritic maturation and synapse formation.
29 requirement for mRNA during early stages of synapse formation.
30 ficant reduction in motor-learning-dependent synapse formation.
31 M that envelops mature neurons and restricts synapse formation.
32 orebrain during the postnatal period of peak synapse formation.
33 xin-1, Munc18-1, and/or SNAP-25, well before synapse formation.
34 migration, neuritogenesis, axon guidance and synapse formation.
35 r neurexin surface transport or heterologous synapse formation.
36 s sufficient to induce functional inhibitory synapse formation.
37 uired for outer retina lamination and ribbon synapse formation.
38 d severe defects in dendritic refinement and synapse formation.
39 y (NgR1, NgR2, and NgR3) restrict excitatory synapse formation.
40 ng axon guidance, dendrite arborization, and synapse formation.
41 oth genes and phenotypic classes involved in synapse formation.
42 ecreted molecule Shh and its receptor Boc in synapse formation.
43 molecules involved in neurite outgrowth and synapse formation.
44 after the proliferation phase of perisomatic synapse formation.
45 r cues regulating the spatial specificity of synapse formation.
46 urons, a high ProN/N-cad ratio downregulates synapse formation.
47 Morphology-1) regulates axon termination and synapse formation.
48 n TCR signaling, as well as on immunological synapse formation.
49 nd rate limiting steps during the process of synapse formation.
50 trate that is required for MT3-MMP-dependent synapse formation.
51 ribute to Sonic hedgehog (Shh) signaling and synapse formation.
52 ein, RTN3, a reticulon protein implicated in synapse formation.
53 ng RNA topoisomerase reaction, and promoting synapse formation.
54 cts in vertebrate motoneuron development and synapse formation.
55 ogenic thrombospondin 1 (TSP-1) release, and synapse formation.
56 aberrant neurite outgrowth and glutamatergic synapse formation.
57 is a critical and poorly understood step in synapse formation.
58 a and Ank2 are targeted to prevent excessive synapse formation.
59 axon trajectories, synaptic specificity, and synapse formation.
60 brain, such as in dendritic arborization and synapse formation.
61 onal growth and impaired dendritic spine and synapse formation.
62 ic adhesion molecules play critical roles in synapse formation.
63 F186) expressed in the PC AIS during pinceau synapse formation.
64 roles of Celsr3 and Vangl2 in glutamatergic synapse formation.
65 c targets initiates the process of GABAergic synapse formation.
66 at the HIV Env did not disrupt immunological synapse formation.
67 organization of BC axon and impairs pinceau synapse formation.
68 underscoring the importance of FGF-dependent synapse formation.
69 en WASp activation, F-actin assembly, immune synapse formation, actin foci formation, mechanotransduc
72 ing spatial constraints, Kon/Koff rates, and synapse formation, along with in-depth analysis of CAR s
73 o modify its output by way of an increase in synapse formation and a decrease in synaptic release eff
74 ns in the developing mammalian cortex during synapse formation and are enriched at synapses in vivo.
76 hology 1 (RPM-1) is a conserved regulator of synapse formation and axon termination in Caenorhabditis
79 ion that is temporally locked to cholinergic synapse formation and dendritic refinement, thus signifi
80 pearance of dendritic spines, accompanied by synapse formation and elimination may underlie the exper
81 thic pain states through abnormal excitatory synapse formation and enhanced presynaptic excitatory ne
82 he structure and function of synapses during synapse formation and experience-dependent synaptic plas
84 hBs act as a central organizer of excitatory synapse formation and function, and as a key regulator o
85 factors that work synergistically to enhance synapse formation and function, and support neuronal gro
86 strates the requirement of SPAG6 for optimal synapse formation and function, its direct role in immun
87 in development, including neurite outgrowth, synapse formation and function, long-term and homeostati
88 al about the molecules that support chemical synapse formation and function, we know little about the
89 as a novel deafness gene required for ribbon synapse formation and function, which is critical for so
92 ubiquitin ligases that function to regulate synapse formation and growth in mammals, zebrafish, Dros
93 cells in the central nervous system, promote synapse formation and help to refine neural connectivity
94 corticospinal axon regeneration, functional synapse formation and improved skilled forelimb function
95 the CD4 T cell immunological synapse affects synapse formation and intracellular signaling to impact
97 -45A is disposable for NK cell immunological synapse formation and lytic granules reorientation but c
98 fication of cellular and molecular events in synapse formation and maintenance is a key step to under
99 s a key role in promoting learning-dependent synapse formation and maintenance on selected dendritic
104 lt nervous system and a crucial regulator of synapse formation and maturation during post-injury remo
105 ole of IKK/NF-kappaB-Igf2-Igf2R signaling in synapse formation and maturation in adult mice, thus pro
106 al knock-outs, we found excessive excitatory synapse formation and maturation in the cortices of P21
108 t developmental origins influence fine-scale synapse formation and microcircuit assembly of neocortic
110 restored CD8 T-cell cytotoxicity and immune synapse formation and normalized T-cell cytokines and pr
111 t transcellular competitive processes govern synapse formation and number in developing cortex and th
112 the actin cytoskeleton during the phagocytic synapse formation and phosphorylation of extracellular s
115 ival and metabolism, neuronal morphogenesis, synapse formation and plasticity, and learning and memor
117 and astrocytes perform critical functions in synapse formation and refinement in the developing brain
118 nin signaling pathway promotes neurogenesis (synapse formation and remodeling) and inhibits neurodege
119 transmembrane molecules sufficient to induce synapse formation and several intracellular scaffolding
120 prising link between electrical and chemical synapse formation and show that Nbea acts as a critical
121 development and its activation may modulate synapse formation and stability through both pre- and po
122 65 (Np65) highly expressed during periods of synapse formation and stabilization is present at the pr
123 owever, after a period of 3 weeks or longer, synapse formation and stabilization were compromised whe
126 of neuroligins in vivo in the regulation of synapse formation and synapse number has been difficult
127 but not PSD-93, are necessary for excitatory synapse formation and synaptic AMPA receptor (AMPAR) loc
128 sults suggest that the influence of menin on synapse formation and synaptic plasticity occur via modu
131 In motoneuron-astrocyte contact cocultures, synapse formation and synaptic transmission were signifi
134 ppocampal neurons respond and integrate into synapse formation and transmission in cultured neuronal
135 developmental switch from axon elongation to synapse formation and transmission that doubles as a sup
140 ears of life, based on anatomical studies of synapse formation, and establishment of intracortical an
141 y "exhausted" T cells, defective immunologic synapse formation, and immunosuppressive myeloid cells.
142 mechanism for continued circuit plasticity, synapse formation, and integration of new neurons in the
143 lved in Alzheimer's disease, plays a role in synapse formation, and is upregulated in intellectual di
145 role in leukocyte trafficking, immunological synapse formation, and numerous cellular immune response
147 rface expression of other membrane proteins, synapse formation, and presynaptic function were unaffec
148 s important for normal neuronal development, synapse formation, and proper propagation of action pote
149 cytes can eliminate dendritic spines, induce synapse formation, and regulate neurotransmission and pl
150 ction of rapsyn and a role of neddylation in synapse formation, and reveals a potential target of the
151 ble ways in which neurotransmitter may drive synapse formation, and speculate on how the environment
152 prevented reorganization of actin filaments, synapse formation, and synaptic AMPAR trafficking in res
154 ith an RNA-binding protein, FMRP, to promote synapse formation; and Top3beta gene deletion has been l
155 we show that radial bundle fasciculation and synapse formation are disrupted when Pou3f4 (DFNX2) is d
158 rise to mossy fibers--and promotes GABAergic synapse formation as a result of release from axons.
159 inals that expressed VGLUT1 increased during synapse formation, as did expression of VGLUT1 at indivi
160 emonstrate Kirrel3 regulates target-specific synapse formation at hippocampal mossy fiber (MF) synaps
161 ervation, rather than specifically affecting synapse formation at the NMJ, and that the regulation of
162 initial RAG binding events and characterize synapse formation at the single-molecule level, yielding
164 gulators of neuronal development function in synapse formation, axon guidance, and axon termination.
165 shapes bipolar-->ganglion cell glutamatergic synapse formation, beginning around the time of eye-open
166 inhibit Zap70 catalytic activity we examined synapse formation between cytotoxic T lymphocytes and th
167 l steps, the molecular mechanisms underlying synapse formation between group Ia proprioceptive sensor
168 red hippocampal mouse neurons did not impair synapse formation between neurons, but blocked heterolog
169 relates to a coordinated inhibitory chemical synapse formation between sparsely labelled interneurons
170 LFA-1, a critical molecule for immunological synapse formation between T cells and APCs, and for cyto
171 synaptic proteins likely affect not only on synapse formation but also on ongoing synaptic function.
172 cal modifications, including myelination and synapse formation, but also pruning of aberrant connecti
173 ceptor (TCR) microclusters and immunological synapse formation, but no study has integrated and quant
174 s, Lrp4 acts bidirectionally and coordinates synapse formation by binding agrin, activating MuSK and
175 e axonal transport of synaptic materials and synapse formation by controlling the nucleotide state of
176 A may regulate activity-dependent inhibitory synapse formation by coordinately eliminating certain na
178 that Sema4D, via PlexinB1, acts to initiate synapse formation by recruiting molecules to both the pr
179 h, the MuSK receptor initiates neuromuscular synapse formation by restricting presynaptic growth cone
180 functions of Rem2 in neurons: regulation of synapse formation, dendritic morphology, and voltage-gat
183 e report impairments in dendritic growth and synapse formation early on during Purkinje cell developm
185 remains unclear, as does the extent to which synapse formation enhances the stability of newly formed
186 into close contact with each other to enable synapse formation for lineage and stage specific V gene
187 vide neurotrophic support; are implicated in synapse formation, function, and pruning; and help maint
188 hat are thought to contribute to early spine synapse formation; however, the actin regulatory protein
189 , we found that NCAM loss during perisomatic synapse formation impairs the process of basket cell axo
191 oopted by CLL cells to induce impaired actin synapse formation in both allogeneic and autologous T ce
193 neuroligins are generally not essential for synapse formation in CA1 pyramidal neurons but shape syn
195 icate that it is not required for structural synapse formation in dentate granule cells or for Shh-de
196 lexinA2 interactions that inhibit excitatory synapse formation in developmentally born and adult-born
197 NgR1 is sufficient to accelerate excitatory synapse formation in dissociated cortical neurons and in
198 , axonal targeting, dendritic branching, and synapse formation in Drosophila, novel features related
199 mitochondrial development, neurogenesis and synapse formation in hiPSCs-derived cortical neurons.
201 Cdc42 in presynaptic neurons is required for synapse formation in monosynaptic sensory-motor circuits
202 , we show that the Rho GTPase Cdc42 controls synapse formation in monosynaptic sensory-motor connecti
203 lasmic tail was dispensable for heterologous synapse formation in neurexin-deficient neurons, as long
204 restored surface transport and heterologous synapse formation in neurexin-deficient neurons, suggest
207 s antigen receptor signaling in lymphocytes, synapse formation in neurons, and bacterial adhesion to
208 e horizontal cell contribution to rod ribbon synapse formation in PlexA4(-)/(-) retinas is disrupted.
209 to visualize differential allogeneic immune synapse formation in polyclonal CD4(+) T cells using hig
210 at Sema4D is sufficient to promote GABAergic synapse formation in rodent hippocampus and investigate
219 ptic sensory neurons is essential for proper synapse formation in the development of monosynaptic sen
222 Despite their apparent behavioral rescue, synapse formation in these fish was significantly altere
223 ons, but the molecular mechanisms underlying synapse formation in these monosynaptic sensory-motor co
224 observed for APLP1, is essential for proper synapse formation in vitro and synapse maintenance in vi
225 C. elegans SYG-1's specification of proper synapse formation in vivo closely correlates with the he
227 xact temporal relationship between spine and synapse formation in vivo remains unclear, as does the e
231 Despite these differences, neuromuscular synapse formation in zebrafish and mice share similar me
232 on between neurons, but blocked heterologous synapse formation induced by neuroligin-1 or LRRTM2.
234 ocus is on novel glial molecules that induce synapse formation, inhibit synapse formation, or control
235 t7a has been implicated in axon guidance and synapse formation, investigations of its role in the ear
236 ) triggering signalosome assembly and immune synapse formation invoke actin-dependent mechanisms.
240 talytic activity Vav-1 activation occurs and synapse formation is arrested at a stage with actin and
243 was hypothesized, given evidence that local synapse formation is dependent on dendritic translation
244 resent techniques conversion is inefficient, synapse formation is limited, and only small amounts of
247 ted neurons are positioned in the volume and synapse formation is restricted to biological bouton den
248 an CD4(+) T cells, and, during immunological synapse formation, it transiently redistributed to the T
250 s that at the initial stage of immunological synapse formation, LZTFL1 is concentrated at the APC con
251 GF-1) pathway as well as pathways related to synapse formation, maintenance and neuronal differentiat
252 e mechanism described here likely applies to synapse formation, maintenance, and function in multiple
254 ells are emerging as important regulators of synapse formation, maturation, and plasticity through th
255 X-linked mental retardation in humans; thus, synapse formation mediated by EphB/SAP102/PAK signaling
257 issue repair and regeneration by stimulating synapse formation, neurite outgrowth, and neuronal survi
258 ays involved in brain development, including synapse formation, neuron differentiation, cell adhesion
259 d to axon guidance (associated with SEMA6D), synapse formation (NTNG1), and neuronal specification (H
264 ic questions extending from axonal guidance, synapse formation, or axonal transport to the developmen
265 cules that induce synapse formation, inhibit synapse formation, or control synaptic levels of glutama
266 tal alteration in dendritic arborization and synapse formation, our findings provide new insights int
268 this cross-dressed MHC can assist in immune synapse formation prior to the induction of full T cell
269 understanding of the molecular mechanisms in synapse formation provides insight into both learning an
270 In Aplysia sensory-motor neuronal cultures, synapse formation rapidly redistributes the mRNA encodin
271 veral days and weeks revealed that, although synapse formation rates were unaffected, boutons on inju
276 systems that play key roles in immunological synapse formation, shear-dependent thrombus formation, a
277 uggest that they do not play a major role in synapse formation.SIGNIFICANCE STATEMENT Human neuroligi
280 g and cell aggregation, but failed to induce synapse formation, suggesting that IgSF9 acts as a cell
281 domain or catalytic residue fail to promote synapse formation, suggesting that Top3beta requires bot
282 n synaptic function and as key regulators of synapse formation, synaptic activity, plasticity, and sy
283 protein of postsynaptic density involved in synapse formation, synaptic plasticity, and synaptic tar
284 l process that more closely resembles immune synapse formation than it does conventional chemotaxis.
286 el roles for APP in regulating neuromuscular synapse formation through hetero-oligomeric interaction
288 iverse physiological functions, ranging from synapse formation to formation of the kidney filtration
290 ently stable in vivo to allow for functional synapse formation under the conditions of perpetual cell
291 suggest that neurexins mediate heterologous synapse formation via an extracellular interaction with
293 ty for T-cell activation and superior immune synapse formation when compared with paired peripheral b
294 dogenous Asef2 with shRNAs impairs spine and synapse formation, whereas exogenous expression of Asef2
295 Neural circuit wiring relies on selective synapse formation whereby a presynaptic release apparatu
296 ial metabolism and network, neurogenesis and synapse formation, while Mfn2 overexpression enhances mi
297 tin cytoskeleton in TCR signaling and immune synapse formation with an emphasis on how poroelasticity
299 rate that Gpc4-deficient mice have defective synapse formation, with decreased amplitude of excitator
300 dent protein kinase only suppresses chemical synapse formation without effects on neuronal growth and
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