ライフサイエンスコーパス: synaptic event

1 le consuming only approximately 1-100 fJ per synaptic event.

2 equency and increased amplitude of GABAergic synaptic events.

3 in the amplitude of spontaneously occurring synaptic events.

4 creases in the rate of observable inhibitory synaptic events.

5 onsistently decreased the rate of observable synaptic events.

6 ls into the dendrites, and reduce excitatory synaptic events.

7 on the millisecond time scale of individual synaptic events.

8 govern a transition from slow to fast phasic synaptic events.

9 pate in network activity and produce complex synaptic events.

10 d to minimize wiring and conduction delay of synaptic events.

11 y close in their kinetics to alpha1-mediated synaptic events.

12 hose underlying the generation of inhibitory synaptic events.

13 the frequency and amplitude of glutamatergic synaptic events.

14 er inputs received high rates of spontaneous synaptic events.

15 s, and partial philanthotoxin sensitivity of synaptic events.

16 d EPSP amplitudes to that of the spontaneous synaptic events.

17 ut not in the average size of multivesicular synaptic events.

18 cantly increased the frequency of excitatory synaptic events.

19 hannels and the integration of glutamatergic synaptic events.

20 rolling the temporal summation of excitatory synaptic events.

21 by an increase in the frequency of miniature synaptic events.

22 ectively, produced an increase in excitatory synaptic events.

23 ents rather than on the average frequency of synaptic events.

24 ich are generated following the summation of synaptic events.

25 Unique downstream gene sets controlling synaptic events and cellular homeostasis for proper matu

26 t is manifested as an increased frequency of synaptic events and increased extrasynaptic conductance,

27 acid (AMPA) receptor-mediated miniature post synaptic events and increased neuronal excitability.

28 ces using in vitro patch-clamp recordings of synaptic events and multiscale imaging of synaptic marke

29 n can be induced by precisely timed pairs of synaptic events and postsynaptic spikes.

30 area CA1, buffers glutamate released during synaptic events and prolongs the time course of its clea

31 al Ca(2+) have been shown to occur with both synaptic events and spontaneous electrical activity invo

32 ings support a motor origin for song-related synaptic events and suggest an updated circuit model for

33 n inverse relationship between the number of synaptic events and the accumulation of cofilin rods in

34 The rate of endogenous synaptic events and the amplitude of nerve-evoked excita

35 ore, parallel changes in the kinetics of the synaptic events and the distribution of spines indicated

36 ses, through two identified calcium signals, synaptic events and their efficacy in eliciting spikes.

37 iring of individual SGNs in response to each synaptic event, and enhances coincident activity of neig

38 ht consistently elevated rates of observable synaptic events, and SNP-evoked increases of excitatory

39 NGFCs received low-frequency spontaneous synaptic events, and stimulation of perforant path fiber

40 f synaptic drive, including the frequency of synaptic events, and the paired-pulse ratio of synaptic

41 These more rapid synaptic events are selectively mediated by non-NMDA rec

42 Recent work, however, suggests that synaptic events arising from action potential (AP)-indep

43 ced the amplitude of the train of inhibitory synaptic events associated with an oscillation and enhan

44 e-specific retinogeniculate segregation, the synaptic events associated with this process, and the im

45 olved in homeostatic regulation of miniature synaptic events at excitatory synapses in response to ac

46 ll and cannot match the size of real unitary synaptic events, but we can obtain a good fit to data wh

47 wledge, new method for detecting spontaneous synaptic events by deconvolution, using a template that

48 Similarly the facilitation of synaptic events by paired-pulse stimuli, and LTP induced

49 igo et al. identify a new class of miniature synaptic event, called "preminis," that originate from a

50 Understanding how brief synaptic events can lead to sustained changes in synapti

51 To explore how these synaptic events contribute to behavioral circuits, we ha

52 Excitatory synaptic events contributed little to seizure activity.

53 receptor-dependent synaptic plasticity, the synaptic events controlling the plasticity of GluR2-lack

54 ons of MCH on both excitatory and inhibitory synaptic events, coupled with opposing excitatory action

55 the two sexes: the frequency of spontaneous synaptic events decreased significantly in neurons deriv

56 y up to 35%, but the frequency of inhibitory synaptic events did not scale with the number of transpl

57 mission, the quantal properties of miniature synaptic events do not match those derived from synaptic

58 The success rate of synaptic events evoked at a frequency range of 0.1-10 Hz

59 aptic events do not match those derived from synaptic events evoked by action potentials.

60 ling to interneurons, such that subthreshold synaptic events from a single principal cell are suffici

61 Furthermore, isolated, large-amplitude synaptic events (>100 pA) occurred more frequently in tr

62 wever, as dopamine does not directly evoke a synaptic event in MSNs, the time course of dopamine sign

63 ber of tetrodoxin- and bicuculline-sensitive synaptic events in > 80% of cholinergic- and GABA-type n

64 dendritic GABA receptor-mediated inhibitory synaptic events in adult mouse hippocampal CA1 pyramidal

65 function, including measures of spontaneous synaptic events in CA1 pyramidal cells.

66 rgic (GABAergic) and spontaneous glycinergic synaptic events in CPNs was significantly increased.

67 ncy of spontaneous excitatory and inhibitory synaptic events in ganglion cells.

68 A reliable method for recording evoked synaptic events in identified neurons in Caenorhabditis

69 ous, and evoked cholinergic and serotonergic synaptic events in pyramidal cells and interneurons of a

70 nist-induced depolarizing responses and slow synaptic events in submucosal neurons.

71 r, these results reveal a role for miniature synaptic events in the acute regulation of dendritic pro

72 mal sensitivity of spontaneous and miniature synaptic events in TRPV1+ and TRPV1- second-order NTS ne

73 anding motivation for following cellular and synaptic events in vivo (intravital microscopy), until r

74 e in the frequency of spontaneous excitatory synaptic events in vivo, which correlated with the numbe

75 ce-dependent scaling of miniature inhibitory synaptic events, in contrast to the scaling of excitator

76 Ca2+ sources for these local synaptic events included NMDA receptors, voltage-depende

77 of proteins has been implicated in important synaptic events including neurotransmitter release and s

78 l frequency but not the quantal amplitude of synaptic events increased more than threefold for null-s

79 al lemniscus that turns extremely well-timed synaptic events into a signal code that is three orders

80 ed for associative LTP and the conversion of synaptic events into long-term emotional memory.

81 mmatory IL-1beta in triggering molecular and synaptic events involved in neurodegenerative processes

82 at this regulation is part of the cascade of synaptic events involved in the consolidation of memory.

83 vation with spontaneous, naturally occurring synaptic events is capable of inducing LTP.

84 captured by a model in which each excitatory synaptic event leads to an immediate reduction in synapt

85 Interestingly, synaptic events mediated by alpha6beta3 or alpha6beta3ga

86 results because in single cell cultures all synaptic events mediated by AMPARs should be detected.

87 s as either (1) trains of GABA(A) inhibitory synaptic events mediated by depolarization of both pyram

88 During neuronal development synaptic events mediated by GABAA receptors are progress

89 receptors, providing a window on the hidden synaptic events mediating discrete psychological process

90 vealed decreased amplitude of AMPAR-mediated synaptic events (mEPSCs) with MCH treatment.

91 h action potentials and miniature excitatory synaptic events (minis).

92 of NMDA receptor (NMDAR) mediated miniature synaptic events ("minis") rapidly scales up synaptic str

93 As expected for vesicular release, first synaptic events occurred earlier as presynaptic calcium

94 hus prompting us to investigate cellular and synaptic events occurring before cell death that may con

95 refore, the spontaneous miniature excitatory synaptic events of approximately 1 mV, as also observed

96 both suprathreshold spiking and subthreshold synaptic events of single neurons in the brain.

97 Both excitatory and inhibitory synaptic events participate during the network oscillati

98 s both the amplitude and width of inhibitory synaptic events profoundly increased under deep anesthes

99 est multiple possible functions, its role in synaptic events remains unknown.

100 were severalfold faster than for glycinergic synaptic events reported previously.

101 indicate that alpha-CaMKII may modulate the synaptic events required for the consolidation of memory

102 Miniature synaptic events, resulting from spontaneous presynaptic

103 Further analysis of the Int E449K-attL/attR synaptic events revealed a preference for one of the two

104 anced N-methyl-D-aspartate receptor-mediated synaptic events, serving an essential function in the in

105 related with the frequency of the background synaptic events, so that cells with weak but numerous mo

106 A(A) receptors are typically extremely rapid synaptic events that do not last beyond a few millisecon

107 n neurons within HVC exhibit precisely timed synaptic events that may represent the ongoing motor pro

108 substance P does not appear to mediate fast synaptic events that underlie nociception in the spinal

109 a tonic and respiratory-modulated barrage of synaptic events that were blocked by intrathecal kynuren

110 a biochemical sensor that couples miniature synaptic events to local translational suppression in ne

111 e signal-transduction mechanisms that couple synaptic events to protein translational machinery durin

112 In the absence of spikes, synaptic events trigger potentiation.

113 2+) fluorescence transients evoked by single synaptic events under physiological conditions.

114 urse of free glutamate in the cleft during a synaptic event was estimated by measuring the extent to

115 Spontaneous synaptic events were also inhibited when either of these

116 Glutamatergic synaptic events were blocked by kynurenic acid, leaving

117 ents, and SNP-evoked increases of excitatory synaptic events were blocked by pretreatment with glutam

118 amplitude and kinetics of individual evoked synaptic events were measured to reveal the patterns and

119 an in vitro brainstem slice preparation, and synaptic events were recording using whole cell voltage

120 -pass filters by responding only to discrete synaptic events while ignoring temporally summed EPSPs.

121 onsistently increased the rate of observable synaptic events while TRIM consistently decreased the ra

122 The pairing of ten single evoked excitatory synaptic events with ten postsynaptic single action pote

123 processing at the level of single spikes and synaptic events, yielding a widely applicable tool for n