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1 e of impaired synaptic formation/maturation (synaptogenesis).
2 s C. elegans orthologue MIG-10 also supports synaptogenesis.
3 ensable of molecular events occurring during synaptogenesis.
4 diates glutamate receptor trafficking during synaptogenesis.
5 e transcription factor UNC-3 is required for synaptogenesis.
6 he coordination of dendritic morphology with synaptogenesis.
7 survival, axon outgrowth, axon guidance, and synaptogenesis.
8 d electrophysiological maturation, including synaptogenesis.
9 the period of heightened postnatal cortical synaptogenesis.
10 ctural features are important in instructing synaptogenesis.
11 t for axon guidance, dendrite formation, and synaptogenesis.
12 protein and proteoglycan interactions during synaptogenesis.
13 al vs extrasomal) in chemical and electrical synaptogenesis.
14 f afferents and targets during the period of synaptogenesis.
15 toxicity and promoted dendrite branching and synaptogenesis.
16 leads to impairment of neuronal function and synaptogenesis.
17 e metalloproteinases (MT-MMPs) in excitatory synaptogenesis.
18 rentiation, migration, neurite outgrowth and synaptogenesis.
19 ors utilize the Tiam1-Bcr complex to control synaptogenesis.
20 signaling cascades, and promotes excitatory synaptogenesis.
21 nslation of p250GAP, a negative regulator of synaptogenesis.
22 eceptor expression or enhanced glutamatergic synaptogenesis.
23 barrel cortex by sensory deprivation during synaptogenesis.
24 orticospinal pathways, neuronal pruning, and synaptogenesis.
25 to young adult development, coincident with synaptogenesis.
26 comes highly phosphorylated at serine-9 upon synaptogenesis.
27 Conversely, increased Mafb accelerates synaptogenesis.
28 n growth, and terminal axon branching during synaptogenesis.
29 ms that glial cells use to regulate neuronal synaptogenesis.
30 ble if PSD-95 expression is prevented during synaptogenesis.
31 gration and adhesion, neurite outgrowth, and synaptogenesis.
32 r astrocytes, are key regulators of neuronal synaptogenesis.
33 146a, which inhibited neuroligin 1-dependent synaptogenesis.
34 driving synaptic scaffold recruitment during synaptogenesis.
35 s critical for regulation of adhesion during synaptogenesis.
36 developmental functions of astrocytes during synaptogenesis.
37 o-activator 1alpha inhibits spinogenesis and synaptogenesis.
38 Isl1SS subset and inhibits branch growth and synaptogenesis.
39 including cell migration, axon guidance, and synaptogenesis.
40 onal roles in axon guidance and in GABAergic synaptogenesis.
41 hfinding but were downregulated beginning in synaptogenesis.
42 -response profiles for neurite outgrowth and synaptogenesis.
43 s is dependent on neuronal activity prior to synaptogenesis.
44 during postnatal development coinciding with synaptogenesis.
45 ressed on cortical neurons before and during synaptogenesis.
46 igh-throughput and quantitative screening of synaptogenesis.
47 hfinding to dendrite growth and branching to synaptogenesis.
48 , neuronal plasticity, spine maturation, and synaptogenesis.
49 hippocampus and showed increased excitatory synaptogenesis.
50 gest that Ribeye plays an organizing role in synaptogenesis.
51 us NT-3 is necessary for SGN axon growth and synaptogenesis.
52 role in horizontal cell differentiation and synaptogenesis.
53 binding of VCP to NF1, resulting in reduced synaptogenesis.
54 oss-of-function mutant in inducing GABAergic synaptogenesis.
55 d scaffolding molecules necessary for proper synaptogenesis.
56 n that plays a role in synaptic adhesion and synaptogenesis.
57 an unavoidable concomitant of rapid adaptive synaptogenesis.
58 ved in neuritogenesis, dendritic growth, and synaptogenesis.
59 roligins and link astrocyte morphogenesis to synaptogenesis.
60 uding axon guidance, target recognition, and synaptogenesis.
61 xon wiring, such as elongation, pruning, and synaptogenesis.
62 ll differentiation, neuronal innervation and synaptogenesis.
63 development, dendritic spine formation, and synaptogenesis.
64 erate the substrate for specific patterns of synaptogenesis.
65 endrite arborisation, neuronal survival, and synaptogenesis.
66 re, which may arise from abnormal excitatory synaptogenesis.
67 twork essential for neuronal development and synaptogenesis.
68 fferentiation, including dendritogenesis and synaptogenesis.
69 f GABAARs influences their ability to induce synaptogenesis, a co-culture model system incorporating
70 urite outgrowth, dendritic arborization, and synaptogenesis all exhibited bidirectional concentration
71 h exclusive CNS expression, is implicated in synaptogenesis and AMPA receptor recruitment to immature
72 Because LRRK2 expression levels rise during synaptogenesis and are highest in dorsal striatal spiny
73 hich serve as a necessary component for both synaptogenesis and axonal branch formation, directly reg
75 in dorsal spinal cord to promote excitatory synaptogenesis and central sensitization that contribute
76 these V1-IN subclasses is determined before synaptogenesis and circuit formation by a process that i
77 activity either enhances or impairs de novo synaptogenesis and circuit integration of neurons, but h
81 other activity-dependent processes, such as synaptogenesis and dendritic growth, remain unaffected d
83 n of the serotonin 5-HT(7) receptor promotes synaptogenesis and enhances synaptic activity in hippoca
84 postsynaptic CAMs work in concert to control synaptogenesis and establish a general framework for GAB
85 ble adhesive contacts that are important for synaptogenesis and for tuning synaptic transmission.
87 determination and migration, axon guidance, synaptogenesis and function, behavioral neurogenetics, a
88 sed numerous genes and proteins critical for synaptogenesis and gap junction formation, concomitant w
89 od after AIE, suggesting aberrant excitatory synaptogenesis and hyperexcitability in memory-related c
92 n kinase A (PKA) activity in the SPNs during synaptogenesis and in response to dopamine receptor Drd1
93 orn was associated with increased excitatory synaptogenesis and increased frequency, but not the ampl
95 lthough the role of mature BDNF on GABAergic synaptogenesis and maintenance has been well studied, an
97 ptic densities, regulates activity-dependent synaptogenesis and mature synapse number on cortical lay
98 Neurexins and neuroligins play a key role in synaptogenesis and neurexin-neuroligin adhesion is one o
99 We generated mixed neural cultures analyzing synaptogenesis and neuronal activity using a multielectr
100 to the deregulation of gene sets involved in synaptogenesis and neuronal transmission, all implicated
101 hippocampal synaptic deficits, by promoting synaptogenesis and neurotransmission at glutamatergic te
103 luRs) play important roles in the control of synaptogenesis and neurotransmitter release, yet their r
104 nal enrichment for transcription regulation, synaptogenesis and other basic intracellular processes.
106 ity to promote neuronal survival, outgrowth, synaptogenesis and phagocytosis, and induce the death of
107 rate a novel mechanism underlying inhibitory synaptogenesis and provide new insights in understanding
108 c studies show that ketamine rapidly induces synaptogenesis and reverses the synaptic deficits caused
110 lar and molecular mechanisms that coordinate synaptogenesis and synapse elimination are poorly unders
111 neuroligin 1 and neuroligin 3, have roles in synaptogenesis and synaptic maintenance that appear larg
113 iminating alpha2delta4 in mice abolishes rod synaptogenesis and synaptic transmission to rod ON-bipol
114 opment of neural circuits through regulating synaptogenesis and that SRPX2 is a synaptogenic factor t
115 tamate receptor GluR1, resulting in abnormal synaptogenesis and transmission in the developing SPNs.
116 These populations selectively contribute to synaptogenesis and tumor pathophysiology, providing a bl
118 y infiltrated the neuropil coordinately with synaptogenesis, and astrocyte ablation reduced synapse n
120 es such as glutamate uptake and promotion of synaptogenesis, and become mature astrocytes by forming
122 ranslation is required for axon guidance and synaptogenesis, and dysregulation of this process contri
123 ostsynaptic scaffolds are recruited to drive synaptogenesis, and Mgat1 mutants exhibit loss of both c
127 lamination of adult retinal neurons, impairs synaptogenesis, and reduces cone photoreceptor survival.
128 e activated calcium channels, is involved in synaptogenesis, and regulates dendritic morphology.
129 or complex/hybrid N-glycans in morphological synaptogenesis, and strengthened functional synapse diff
130 c NR2B over NR2A controls spine motility and synaptogenesis, and suggest a structural role for the in
131 ifferentiation, dendritic and axonal growth, synaptogenesis, and synaptic pruning, all of which can b
132 s, such as axonal outgrowth and pathfinding, synaptogenesis, and the maturation of ion channel and re
133 tin in target cells plays a critical role in synaptogenesis, and this can be exploited by pathogens t
134 ical axons relaying sensory information, (3) synaptogenesis; and (4) development of functional connec
137 e molecular pathways required for electrical synaptogenesis are not well understood, and whether they
140 plays a crucial role during axonogenesis and synaptogenesis as well as in synaptic transmission and p
141 o understanding of the general principles of synaptogenesis as well as of neuromuscular disorders.
142 ncreased cell proliferation, vascularity and synaptogenesis, as well as reduced apoptosis in the hema
143 cite an example from preliminary studies of synaptogenesis at the calyx of Held, a large nerve termi
144 SS neurons display reduced branch growth and synaptogenesis at the hindbrain-spinal cord junction.
146 This elevated neurotransmission enhances synaptogenesis between BCs and RGCs, without altering th
147 This study provides novel insights into synaptogenesis between central neurons revealing both di
151 iods of neurogenesis and migration, up until synaptogenesis, both nitric oxide (NO) and its downstrea
152 mplicated in the control of neurogenesis and synaptogenesis but its potential roles in intervening pr
154 mily, has been shown to have a clear role in synaptogenesis, but its roles in other tissues have not
156 atory motion of the filopodia is crucial for synaptogenesis, but the underlying mechanisms are poorly
157 ribute to many neuronal functions, including synaptogenesis, but their role in the development of syn
158 These results indicate that PKC promotes synaptogenesis by activating PSD-95 phosphorylation dire
159 lasmin proteolysis impairs parallel fiber-PN synaptogenesis by blocking brain-derived neurotrophic fa
161 ndicate that EphBs control axon guidance and synaptogenesis by distinct mechanisms and provide a new
164 n of some BC neighbors resulted in increased synaptogenesis by the remaining axons in a transmission-
165 With a fixed number of neurons, adaptive synaptogenesis can control the speed of synaptic develop
166 tified three conceptually distinct routes to synaptogenesis: cell-cell contact mediated by adhesion p
167 ued the morphological neuronal phenotype and synaptogenesis defects from ASD neuronal co-cultures.
169 o the first developmental milestones such as synaptogenesis, dendrite formation, and maturation of in
171 mutants revealed that APP potently promotes synaptogenesis depending on copper binding to the GFLD.
173 that whereas dNedd4S promotes neuromuscular synaptogenesis, dNedd4Lo inhibits it and impairs larval
175 We investigated the role of NR2 subunits in synaptogenesis during the period in which expression and
176 receptor tyrosine kinases mediate excitatory synaptogenesis early during development, and then later
177 Remarkably, TrkC-IgG reduced axon growth and synaptogenesis even in the presence of BDNF, indicating
179 opose that dysregulation of such specific MN synaptogenesis genes, compounded by many additional tran
180 al factors including regional differences in synaptogenesis, glucose metabolism, and myelination acro
183 ly promotes neurogenesis, neuritogenesis and synaptogenesis; however, the underlying molecular mechan
184 mechanisms that are relevant to depression: synaptogenesis, immunomodulation and regulation of glyco
186 expression of DISC1 suppresses glutamatergic synaptogenesis in developing neuromuscular junctions.
187 show that mouse Sema5A negatively regulates synaptogenesis in early, developmentally born, hippocamp
188 state, results in a selective enhancement of synaptogenesis in gamma-aminobutyric acidergic interneur
189 neural hearing loss and prevented the normal synaptogenesis in inner hair cells (IHCs) in the newly i
190 ansiently coexpressed with FMRP during early synaptogenesis in layer- and region-specific pyramidal n
191 Spontaneous activity is thought to regulate synaptogenesis in many parts of the developing nervous s
196 is characterized by extensive glutamatergic synaptogenesis in striatal spiny projection neurons (SPN
197 ction with immunohistochemistry, to quantify synaptogenesis in the auditory cortex of normal hearing
199 pathways regulating mRNA translation during synaptogenesis in the genesis of neurodevelopmental diso
202 olamine increases glutamate transmission and synaptogenesis in the medial prefrontal cortex (mPFC).
203 mammalian target of rapamycin and increased synaptogenesis in the prefrontal cortex are crucial in m
207 pathway modulating structural and functional synaptogenesis, including the GPI-anchored heparan sulfa
208 regeneration is delayed or absent, blue-cone synaptogenesis increases and ectopic synapses are made w
213 nexplored question is whether the process of synaptogenesis is coordinated with the adoption of speci
214 edly impaired, consistent with the idea that synaptogenesis is dependent on dendritic translation/rel
217 ectively, our results suggest that lateralis synaptogenesis is intrinsically nonselective and that in
219 sm of developmental plasticity wherein rapid synaptogenesis is promoted by the coordinated actions of
220 st that a main role of SYD-2/Liprin-alpha in synaptogenesis is to regulate the polymerization of DPs.
221 We propose that Np65, by regulating IHC synaptogenesis, is critical for auditory function in mam
222 del of synapse development, such as adaptive synaptogenesis, it is possible to study such overproduct
223 ns display abnormal neurogenesis and reduced synaptogenesis leading to functional defects in neuronal
225 sms, regulates postnatal PN dendritogenesis, synaptogenesis, mitochondrial structure and function, an
226 s lost as a result of Pb(2+) exposure during synaptogenesis, namely Synaptophysin (Syn) and Synaptobr
227 NMDA receptors (NMDARs) are critical to synaptogenesis, neural circuitry and higher cognitive fu
228 Elucidating the mechanisms that coordinate synaptogenesis, neuronal activation, and neurotransmitte
229 anisms controlling neural circuit formation, synaptogenesis, neuronal polarity, and dendritic arboriz
234 nges in the odour environment are rapid, the synaptogenesis of adult-born neurons occurs over a longe
235 pic mechanism by which one afferent controls synaptogenesis of another afferent, but not vice versa.
236 by Foxp2 in neonatal mouse striatum controls synaptogenesis of corticostriatal inputs and vocalizatio
241 hat whereas both profilins are needed during synaptogenesis, only PFN2a is crucial for adult spine pl
243 whether spontaneous activity itself promotes synaptogenesis or plays a purely permissive role remains
245 ing and identify the vesicular transport and synaptogenesis pathways as the major targets of the fear
250 unilateral brain damage results in aberrant synaptogenesis, potentially of transcallosal projections
252 nt synapses in D1-type neurons, likely via a synaptogenesis process, whereas morphine induced silent
253 n of glutamate transmission and induction of synaptogenesis, providing novel targets for a new genera
255 role in shutting down expression of specific synaptogenesis-related genes in the cerebellum, resultin
261 ay matter following preadolescence overtakes synaptogenesis, resulting in a more efficient, adult-lik
262 etween SMA motoneurons and astrocytes impair synaptogenesis seen in SMA pathology, possibly due to th
263 neurodevelopment of excitatory postsynaptic synaptogenesis, setting the stage for neuronal interconn
264 d with increased glutamate transmission, and synaptogenesis, similar to N-methyl-D-aspartate receptor
265 nt at postsynaptic specializations is key in synaptogenesis, since this step confers functionality to
267 clear how this switch affects the process of synaptogenesis, synapse maturation, and synapse stabiliz
268 ch supports the positive role of lecithin in synaptogenesis, synaptic development and maturation.
269 pecific microRNA and plays a pivotal role in synaptogenesis, synaptic plasticity and structural remod
270 glutamate receptor (NMDAR) is essential for synaptogenesis, synaptic plasticity, and higher cognitiv
271 eceptors (NMDARs) have a fundamental role in synaptogenesis, synaptic plasticity, and learning and me
272 on through the modulation of neuritogenesis, synaptogenesis, synaptic plasticity, and memory consolid
273 and function, including neuronal migration, synaptogenesis, synaptic plasticity, and myelination.
274 pecifically, the adaptive algorithm includes synaptogenesis, synaptic shedding, and bi-directional sy
275 sion, with enrichment of genes important for synaptogenesis, synaptic transmission, photoreceptor mor
276 WF), neurogenesis (BrdU TUJ1, DCX and NeuN), synaptogenesis (synaptophysin) and apoptosis (TUNEL).
277 he functional relations of key regulators of synaptogenesis that contribute to both typical cortical
278 ndicate that BAI1 plays an important role in synaptogenesis that is mechanistically distinct from its
279 r of cell-type specific features of auditory synaptogenesis that offers a new entry point for treatin
280 mmune response signaling, axon guidance, and synaptogenesis that significantly influenced DMN modulat
281 gnaling in astrocytes and promote excitatory synaptogenesis, thereby increasing seizure susceptibilit
283 ynaptic adhesion molecules, are important in synaptogenesis through a well-characterized trans-synapt
286 are hyperactive due to increased excitatory synaptogenesis using electrophysiology, calcium imaging,
287 ase C (PKC) promotes synaptic maturation and synaptogenesis via activation of synaptic growth factors
288 sensitization modulates spine formation and synaptogenesis via CREB-mediated miR132 upregulation, wh
289 expression required for dendritogenesis and synaptogenesis via delayed occupancy of target promoters
290 urotrophic factor (NTF)-dependent excitatory synaptogenesis, via two proteolytic fragments generated
293 ting GluN2 subunits in single neurons during synaptogenesis, we find that both GluN2B and GluN2A supp
294 e capable of promoting neuronal survival and synaptogenesis when co-cultured with iPSC-derived neuron
295 y parvalbumin-expressing interneurons during synaptogenesis, whereas Adamts4 mRNA is exclusively gene
296 n target of rapamycin complex 1 (mTORC1) and synaptogenesis, which have been implicated in the rapid
297 sory neuron hyperexcitability and excitatory synaptogenesis, which together lead to central sensitiza
298 pinal cord resulted in abnormal motor neuron synaptogenesis, which was not rescued by immigration of
299 RGFP968, were most effective at stimulating synaptogenesis, while the selective HDAC3 inhibitor, RGF
300 ponds to the period of process outgrowth and synaptogenesis, with robust expression in hippocampal an
301 arisons confirmed massive cell death, before synaptogenesis, within 1-4 DIV upon loss of t-SNAREs (sy
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