ライフサイエンスコーパス: synergistic action

1 tion, consistent with this being the mode of synergistic action.

2 different cancer types to identify modes of synergistic action.

3 l to understand the molecular basis of their synergistic action.

4 Furthermore, through synergistic action between IL-17 and interferon-gamma, T

5 t.3-mediated release of nitric oxide and the synergistic action between OX42 and beta25-35 in inducin

6 Following the discovery of synergistic action between oxacillin and manuka honey ag

7 respectively, of the cells, demonstrating a synergistic action between PAF and TNF-alpha.

8 Finally, potential synergistic actions between Al (AlQ and Al-S) and beta-a

9 Synergistic actions between all-trans-retinoic acid (atR

10 ormation on metallic Ni and the second via a synergistic action by Ni and ZrO(2) through adsorbing th

11 High sensitivity to PSMA resulted from synergistic action by two different ligands to PSMA on t

12 that generated the greatest antagonistic or synergistic actions, compared with a theoretically neutr

13 These synergistic actions dramatically prevent the post-ischem

14 The results illustrate two mechanisms of synergistic action: First, maximal leakage requires an o

15 sistent with a principal role for Nogo-A and synergistic actions for MAG and OMgp, presumably through

16 e tolerance, the mechanisms underlying their synergistic actions have not been established.

17 ion is thus proposed to reflect the positive synergistic action in female liver of liver-enriched and

18 phages and RIT, suggesting the potential for synergistic action in vivo.

19 DA receptor sensitivity is attributable to a synergistic action involving increased phosphorylation a

20 optimal doses of IMQ and IFN-alpha exhibited synergistic action, leading to optimal TRAIL expression

21 The synergistic actions mediated by alpha7 nAChRs and NMDA r

22 The synergistic action of 5-HT plus phasic CCK may then acti

23 pharmacogenetic" approach that relies on the synergistic action of a drug (rapamycin) and a genetic m

24 Yeast one-hybrid assays demonstrated synergistic action of ABI4 with ABI5 or related bZIP fac

25 es with the plasma membrane is driven by the synergistic action of AIIt and arachidonic acid.

26 In conclusion, synergistic action of all 3 mutations results in a mice

27 rdingly amine-dependent folding occurs via a synergistic action of amines' basicity and the progressi

28 icating that acantholysis in PV results from synergistic action of antibodies to different keratinocy

29 This involves the synergistic action of beta-amylase 1 (BAM1) and alpha-am

30 rd cells, starch is rapidly mobilized by the synergistic action of beta-AMYLASE1 (BAM1) and alpha-AMY

31 ells to gain germ-line competency before the synergistic action of BMP4 and BMP8B.

32 We report that the synergistic action of Bora and the kinase Aurora A (Aur-

33 proximately 100 microM Ca2+ and involves the synergistic action of both C2 domains of synaptotagmin.

34 However, prd function in vivo requires the synergistic action of both the PAI domain and the HD.

35 ration of differentiating cells requires the synergistic action of CDK2 and CDK4.

36 In the present study, the possible synergistic action of CYP2E1 and LPS in liver injury was

37 act as a molecular bridge that controls the synergistic action of dopamine and glutamate on striatal

38 Studies have documented a synergistic action of expansins for cellulose digestion

39 These data are evidence for a synergistic action of fimbrial operons during colonizati

40 e myotomes results at least in part from the synergistic action of GATA and bHLH myogenic factors tha

41 precise biochemical mechanism underlying the synergistic action of gene activators on eukaryotic tran

42 We provide evidence that the synergistic action of GKLF and Sp1 is dependent on the p

43 Our findings show that synergistic action of glia- and neurone-derived ATP can

44 These data suggest that the synergistic action of glucose and GLP-1 to promote insul

45 wo cell types are inversely modulated by the synergistic action of glutamate and acetylcholine acting

46 e signalling in plants, and suggest that the synergistic action of glutamate and glycine at NMDA-like

47 This synergistic action of Hsp33 and Lon was responsible for

48 sion of cellulose was thought to rely on the synergistic action of hydrolytic enzymes, but recent wor

49 mma, or both, while direct activation by the synergistic action of IL-12 and IL-18 leads to IFN-gamma

50 correction of diabetes, indicating that the synergistic action of insulin and glucokinase is needed

51 beta-casein gene promoter is induced by the synergistic action of insulin, prolactin, and glucocorti

52 ssociated with gene expression caused by the synergistic action of intratumoral hypoxia and HIF-1alph

53 -mediated release of Ca(2+) triggered by the synergistic action of IP3 and Ca(2+) released by RyRs.

54 ubiquitinated cellular proteins through the synergistic action of its UBA domains.

55 fungi, Ostrinia nubilalis herbivory, and the synergistic action of jasmonic acid and ethylene.

56 l amounts of IL-6 protein in response to the synergistic action of KL and IL-10 to induce IL-6 gene t

57 Silencing the STAT3 gene abolished the synergistic action of leptin/CCK-8 on neuronal firing.

58 R agonists, up-regulates VEGF, mimicking the synergistic action of LPS with A(2A)R agonists.

59 The synergistic action of miRNA paralogs in development may

60 o a single mechanism acting alone but on the synergistic action of multiple "modes" of lubrication th

61 into the male vs. hermaphrodite fate by the synergistic action of multiple, independent XSEs that re

62 ss the delineation of the heart field by the synergistic action of muscle and gut determinants.

63 expression resulted from the codependent and synergistic action of NANOG and pSTAT3 in embryonic stem

64 te and activates the Pitx2 enhancer with the synergistic action of Nkx2.5.

65 re, we briefly outline current evidence that synergistic action of noradrenaline and cortisol enables

66 ular tumorigenesis, hormonal carcinogenesis, synergistic action of other carcinogens on hormone-induc

67 ut this effect may have been contingent on a synergistic action of phototoxicity from the imaging met

68 Two basic observations defined the synergistic action of PKA as "gating" for neuregulin-Erb

69 /c 3T3 fibroblasts into S phase requires the synergistic action of platelet-derived growth factor (PD

70 modeling is supplied via the cooperative and synergistic action of proteins and lipids, as cellular s

71 suggesting that STAT5 is not involved in the synergistic action of SCF and EPO.

72 dicted human boundaries may function via the synergistic action of sequence-specific recruitment of t

73 ion of the AKT-mTOR pathway, and uncovered a synergistic action of Smad4 and Pten in repressing pancr

74 lts are consistent with a model in which the synergistic action of Sox2 and Oct-3 results from two ma

75 domain is targeted to endosomes through the synergistic action of stereospecific PtdIns(3)P head gro

76 epithelial cells is believed to require the synergistic action of structural coat proteins and mecha

77 on of astrocytic tenascin is mediated by the synergistic action of TGF-beta1 and bFGF in vitro and af

78 machinery and mesoderm formation through the synergistic action of the diversified signal pathways de

79 full transactivation activity relies on the synergistic action of the four exon fragments.

80 s suggest that curvature is generated by the synergistic action of the N-terminal helices embedding i

81 a cells is thought to arise in part from the synergistic action of the transcription factors Pdx1 and

82 alone, providing biological support for the synergistic action of the two ligands.

83 d proliferation in hematopoietic MO7e cells; synergistic action of these factors is blocked by the su

84 nsplant model, we further validated that the synergistic action of these proapoptotic JAK1 targets is

85 Here we report that the synergistic action of two inhibitors of SMAD signaling,

86 Here we describe the synergistic action of two peptides: one from the third i

87 d from corn cell walls were increased by the synergistic action of XynA and cellulases.

88 e-grain intake, which has been attributed to synergistic actions of bioactive compounds.

89 ent of the Th1 phenotype was mediated by the synergistic actions of both cytokines.

90 emokine mRNA and protein generation involves synergistic actions of calcium flux-dependent NFAT trans

91 Here, we demonstrate novel synergistic actions of corticosterone and corticotropin-

92 Therefore, the synergistic actions of corticosterone and CRH at hippoca

93 Here, we demonstrate novel synergistic actions of corticosterone and CRH on hippoca

94 Therefore, synergistic actions of corticosterone and CRH underlie e

95 ed programme is repressed in the dark by the synergistic actions of CUL4(COP1-SPA) E3 ubiquitin ligas

96 However, after chronic cocaine, the combined synergistic actions of DA and CRF switched polarity to e

97 These findings strongly suggest that synergistic actions of glucocorticoids and emotional aro

98 get gene specificity of PR-B depended on the synergistic actions of MAGE-11 and p300 mediated by the

99 n genes are regulated by the cooperative and synergistic actions of many transcription factors.

100 lines, although not in the mouse model, the synergistic actions of MK-2206 and ridaforolimus (MK-866

101 s to determine how alcohol might disrupt the synergistic actions of molecular systems and to assess g

102 While synergistic actions of mu-opioid receptor agonists have

103 division is a complex process requiring the synergistic actions of multiple factors, including mecha

104 The present study examines the synergistic actions of N-(4-hydroxyphenyl) retinamide (4

105 cuss our results with reference to the known synergistic actions of NA with another aminergic neuromo

106 est that PNH in SJS originates distally from synergistic actions of peripheral nerve and neuromuscula

107 In this study, we demonstrated synergistic actions of PGE(2) and the receptor tyrosine

108 itment of many cellular proteins may require synergistic actions of PS and phosphoinositides.

109 ion but that it also plays a key role in the synergistic actions of retinoic acid and cytokines on th

110 These results suggest that the synergistic actions of selective MOR- and DOR-agonists m

111 Furthermore, the synergistic actions of suboptimal concentrations of phor

112 nd provide a mechanistic basis for the known synergistic actions of surface ectoderm/neural tube and

113 d miR-31 were prominently elevated under the synergistic actions of TGF-beta/TNF-alpha.

114 lysis of changes in gene expression revealed synergistic actions of the antibody combination over a b

115 This low rate is attributed to the synergistic actions of Tyr 149 and Ser 124 in wild-type

116 As a possible mechanism of this synergistic action on CAM expression, hypoxia induced a

117 idually administered to SK-N-SH cells, had a synergistic action on cytotoxicity.

118 and fractional sodium excretion, suggesting synergistic actions on tubular transport and vascular sm

119 combination of metformin and sitagliptin had synergistic actions to preserve beta-cell mass and funct

120 imal timing for IR treatment to increase the synergistic action using xenograft models and, later, in

121 This synergistic action was, at least in part, mediated throu

122 as also studied to examine the potential for synergistic action with expansins.

123 protein FKBP12 homolog is required for FK506 synergistic action with fluconazole.

124 hat CBP activity may be mediated through its synergistic action with p53.