ライフサイエンスコーパス: synergistic effect

1 ents in combination with bFGF did not show a synergistic effect.

2 y of these neurotrophic factors has a strong synergistic effect.

3 These results suggest a synergistic effect.

4 vascular wall, and a combined dose showed a synergistic effect.

5 ty, their combination could promote greater, synergistic effects.

6 Thereby, their combinations revealed synergistic effects.

7 nomegaly) were identified to result from VVI synergistic effects.

8 e inhibitor GSK-J4 revealed that the two had synergistic effects.

9 ave different mechanisms of action to afford synergistic effects.

10 rformance is attributed to Fe-doping-induced synergistic effects.

11 ht to identify molecule(s) involved in these synergistic effects.

12 and suggest that combined exposures may have synergistic effects.

13 nique risks that might have additive or even synergistic effects.

14 s were tested to study potential additive or synergistic effects.

15 , their ecological roles, and their possible synergistic effects.

16 eated with venetoclax and romidepsin showing synergistic effects.

17 general atopic disease loci, which can have synergistic effects.

18 elimination of regulatory T cells had potent synergistic effects against metastatic disease that was

19 lass of charged metallopolymers that exhibit synergistic effects against MRSA by efficiently inhibiti

20 It is demonstrated that the synergistic effect allows the exceptional mechanical pro

21 Synergistic effects also allow dynamic programming and t

22 combination of ozone and ultrasound showed a synergistic effect and enhanced the inactivation to 99%

23 urements showed that TCNQ and GO triggered a synergistic effect and exhibited an unexpected electroca

24 al oxo in a frustrated Lewis pair can have a synergistic effect and results in enhanced catalytic act

25 Notably, the hybrid CPT-Cap prodrug showed a synergistic effect and significantly enhanced potency ag

26 scavenging capacity of carotenoids, such as synergistic effects and solubility, are sometimes overlo

27 wth factor receptor (IGF1R) inhibitors had a synergistic effect, and ligand stimulation of EGFR and M

28 The synergistic effects are produced by nuclear factor kappa

29 Synergistic effects arising from the conjugation of orga

30 Here we show that local synergistic effects associated with acquaintances of pai

31 oxyphenyl)-4H-chromen-4-one) has the highest synergistic effect at concentration of 1.3 muM, 11.7-fol

32 cantly enhance by OA treatment, indicating a synergistic effect between BMP2 and OA.

33 with superior properties by using effective synergistic effect between components.

34 the unique 3D hierarchical structure and the synergistic effect between hybrid components, the as-pre

35 no studies have explored whether there is a synergistic effect between LT-age and LT-MELD.

36 Here, based on the synergistic effect between nanowires and orientated mart

37 on on the molecular mechanism reveals that a synergistic effect between Pt, NbOx species and acidic s

38 erior electrochemical performance due to its synergistic effect between rGO and Cn.

39 A synergistic effect between the AMO-LDH and OCNT was obse

40 than its separated components, indicating a synergistic effect between the high and low molecular we

41 This synergistic effect between the two sequential reactions

42 Our study demonstrates that the synergistic effect between TLR4 and TLR3 in macrophages

43 for the CFH and CFI genotypes, suggesting a synergistic effect between vitamin D status and compleme

44 In the present study, we demonstrate that synergistic effects between biogenic ligands and a reduc

45 Unique synergistic effects between phosphonium-alkylphosphate i

46 icient Fe acquisition strategies may rely on synergistic effects between reactive exudates.

47 s a more uncommon mixed-anion catalyst where synergistic effects between sulfur and phosphorus produc

48 The synergistic effects between the hierarchically porous 1D

49 tro and in vivo Consistent with the in vitro synergistic effects between the SK1-specific inhibitor S

50 The success is attributed to synergistic effects between the two drugs.

51 s have been studied separately, the possible synergistic effects between these reactions remain poorl

52 studies using RK-33 and radiation exhibited synergistic effects both in vitro and in a xenograft mod

53 echanisms have the potential for additive or synergistic effects, but experimental design and analyse

54 enhanced conductivities, or even to unclear synergistic effects, but the importance of the defects,

55 3D-hierarchical BRG nanoconstruct exhibited synergistic effect by combining enhanced electrical prop

56 mation on the silica surface combined with a synergistic effect caused by the silica support itself.

57 rcinoma cells in vitro demonstrating a clear synergistic effect (combination index of 0.79).

58 entrations of adsorbed ascorbate and HBED, a synergistic effect could still be identified.

59 These synergistic effects could be decisive for the survival o

60 Integration of these two treatments for synergistic effects could eradicate more tumor cells and

61 ified plaque, but there was no evidence of a synergistic effect due to HIV/HCV coinfection.

62 al molecular stability and also allows for a synergistic effect during collagen folding.

63 However, it is unknown whether a synergistic effect exists.

64 that the combination of RSV, PRF, and HA has synergistic effects, explaining their role as a regenera

65 ences compared to the wild-type enzyme, with synergistic effects for combinations of interaction site

66 monstrate the feasibility of utilizing these synergistic effects for controlling the growth rates and

67 Our analyses also suggest a large synergistic effect from river-ocean mixing, global and l

68 ferent doping levels and configurations, and synergistic effects from co-dopants, hoping to assist a

69 aditional treatments may achieve additive or synergistic effects, further augmenting patient benefit.

70 Our results demonstrate that synergistic effects greatly enhance the reactivity of mi

71 Interestingly, the synergistic effect has also been observed for sarcosine,

72 To test the synergistic effect, high-Killip patients with triglyceri

73 mostly inactive in DTT oxidation, but shows synergistic effect in (*)OH formation in the presence of

74 ticoid treatment in dystrophic muscle have a synergistic effect in alleviating the dystrophic phenoty

75 neous inhibition of p300/CBP and Notch has a synergistic effect in esophageal adenocarcinoma.

76 inase pathway inhibition and showed a strong synergistic effect in halting proliferation and in induc

77 easome inhibitor bortezomib, VR23 produced a synergistic effect in killing multiple myeloma cells, in

78 corticosteroids and their potential additive/synergistic effect in neutrophils from patients with COP

79 TGF-beta/Fc and nonlytic IL-2/Fc exert a synergistic effect in promotion of alloengraftment and d

80 -Cl(-) cotransporter (KCC) - it would have a synergistic effect in protection against sickling, direc

81 Treatment with FK506 produced a synergistic effect in the grafts from AID(-/-) recipient

82 Combining LPS and CX3CL1 displayed a strong synergistic effect in vitro, but HMOX-1 levels were sign

83 ograft tumor models, and we observed similar synergistic effects in a lung cancer xenograft tumor mod

84 the nicotinic partial agonist cytisine have synergistic effects in a mouse model of antidepressant e

85 bosutinib and gefitinib showed additive and synergistic effects in cancer cell lines resistant to EG

86 ed siRNA and its delivery system, to achieve synergistic effects in cancer therapy.

87 n with zoledronic acid displayed additive or synergistic effects in cell growth assays in 10 of 11 ce

88 Hit 7a and lead 7ii both showed synergistic effects in combination with existing HCV dru

89 Lenalidomide has been shown to produce synergistic effects in experimental models when evaluate

90 and memantine (triple combination) produces synergistic effects in extracellular levels of acetylcho

91 se 1 and RhoA/Rho kinase (ROCK) leads to the synergistic effects in KRAS-mutant cancers.

92 Synergistic effects in particular can accelerate ecologi

93 howed that PTEN loss and activated Kras have synergistic effects in promoting development of IPMN and

94 hibition of miR-21, miR-23a, and miR-27a had synergistic effects in reducing proliferation of PDAC ce

95 Inhibition of MIR21, MIR23A, and MIR27A had synergistic effects in reducing proliferation of PDAC ce

96 -1R, Src and c-Met/ALK, respectively) led to synergistic effects in some of the cell lines examined.

97 sed the highest reduction in CML, suggesting synergistic effects in the muffin formula.

98 gen-activated protein kinase signaling shows synergistic effects in the process of melanoma tumorigen

99 Chinese Medicinal (TCM) formulae can achieve synergistic effects in therapeutics and antagonistic eff

100 ed by linker installation, which resulted in synergistic effects including an enhancement of H2 adsor

101 s to uncover pairs of genes with potentially synergistic effects, including a potential synergy betwe

102 th potassium and calcium channels), produced synergistic effects, including an 11.5-fold reduction in

103 or antagonistic (interference), additive and synergistic effect interactions.

104 all antioxidants in the diet by also taking synergistic effects into account.

105 Notably, the synergistic effect is dependent on type I IFN and TNF-al

106 d to increase viral antigen production, this synergistic effect is directly associated with H3K27 dem

107 This synergistic effect is likely the result of both passive

108 The molecular mechanism underpinning this synergistic effect is poorly understood.

109 ures the range of other phenotypes that show synergistic effects is usually unknown.

110 eal that a logic based on local, nonspecific synergistic effects, largely among pioneer TFs, is suffi

111 For DFOB, the synergistic effect lasted for the 168 h duration of the

112 Such synergistic effects lead to superior HER catalytic activ

113 Co-expression of CPK32 and CNGC18 had a synergistic effect leading to more severe depolarization

114 ination of both types of inhibitors produced synergistic effects, leading to complete inhibition at v

115 tivity of cancer cells with a supra-additive synergistic effect of "0 + 1 > 1." Noteworthy is that "D

116 ensitive electrochemical sensor based on the synergistic effect of 7,7,8,8-tetracyanoquinodimethane (

117 This technique, combined with the synergistic effect of active plasma boundary control, en

118 The synergistic effect of alloying with Fe leads to better p

119 We examined the synergistic effect of alpha9 integrin and kindlin-1 on s

120 INTERPRETATION: Our study identified a synergistic effect of amyloid and tau deposits and demon

121 The synergistic effect of anti-ADAMTS13 IgG antibody in the

122 The synergistic effect of As(III) on H2 production can be ex

123 The synergistic effect of As(III) on H2 production shows tha

124 her with HsRAD51, potentially explaining the synergistic effect of attenuating the expression of both

125 r performance was mainly originated from the synergistic effect of B and N co-doping, high N content

126 motherapeutic drug doxorubicin to maximize a synergistic effect of chemosensitization and chemotherap

127 The synergistic effect of chemotherapy and immunotherapy is

128 This is the first study to investigate the synergistic effect of colistin/doripenem combination on

129 ions in the Ebf1 and Pax5 genes, revealing a synergistic effect of combined dose reduction of these p

130 We used this model to investigate the synergistic effect of combined gemcitabine monophosphate

131 The synergistic effect of combining molecular imprinting and

132 by NOTCH1 pathway inhibition and explore the synergistic effect of combining NOTCH inhibition with co

133 Our data demonstrate the synergistic effect of combining PD901 with PBNP-based PT

134 A synergistic effect of DFOB and ascorbate on the rate of

135 Our concept depends on synergistic effect of electrical characterization in com

136 In this study, we investigated the synergistic effect of ethanol and acetaldehyde on the ti

137 Src kinase and MLCK inhibitors blocked this synergistic effect of ethanol and acetaldehyde on tight

138 The synergistic effect of ethyl acetate fractions of seaweed

139 We observed a synergistic effect of FASN inhibitors with gemcitabine i

140 dition, costimulation experiments revealed a synergistic effect of FGF1 and TWEAK in regard to cardio

141 ko habitat selection but did not explain the synergistic effect of fire and elephants.

142 Our results indicated a synergistic effect of formate and lactate on electricity

143 ated SUMOylation drives GA by regulating the synergistic effect of GATA2 and NF-kappaB and consequent

144 These results shed light on the possible synergistic effect of GQs and HQs on transcriptional con

145 ivity of this sensor was good as a result of synergistic effect of graphene and AuNPs (2D and 0D nano

146 The synergistic effect of graphene and AuNPs, which facilita

147 Here, we explored the synergistic effect of HIV-1 Tat and KSHV oncogene Orf-K1

148 HSF1gamma isoforms potentially suppress the synergistic effect of HSF1alpha and HSF1beta co-expressi

149 Strong evidence on the synergistic effect of inclusion of vitamin C rich fruits

150 Based on our findings, we conclude that a synergistic effect of increased availability of feeding

151 nanostructuring of the CoS2 material has the synergistic effect of increasing its operational stabili

152 The synergistic effect of LTC4 with IL-33 was completely dep

153 stant to axotomy-induced death, indicating a synergistic effect of MKK7/MAP2K7 on axotomy-induced dea

154 The synergistic effect of MnO2/PANI plus the unique coaxial

155 increased PTEN synthesis and suppressed the synergistic effect of Nef- and K1-induced angiogenesis a

156 bility, a comprehensive understanding of the synergistic effect of network topology and individual dy

157 The observed increases may be due to the synergistic effect of new traits introduced into corn va

158 The synergistic effect of polymet alongside CDDP demonstrate

159 on dystrophic muscle, but also revealed the synergistic effect of RhoA/ROCK inhibition and glucocort

160 The synergistic effect of SNRIs on AMPARs was blocked by inh

161 ation bursts, few studies have looked at the synergistic effect of such factors.

162 NF-kappaB p65 and ultimately suppressed the synergistic effect of Tat- and K1-induced angiogenesis.

163 ll responses equally well, arguing against a synergistic effect of TCR and inflammatory signals on T

164 Due to the synergistic effect of the constituents, the SnO2 QDs/RGO

165 Furthermore, the synergistic effect of the fast kinetics of electron tran

166 ons we interpret magnetization reversal as a synergistic effect of the metastable ferroelastic switch

167 electrocatalytic activities originate from a synergistic effect of the N, S heteroatom doping and uni

168 newly developed biosensing platform exhibits synergistic effect of the nano-hybrid functional constru

169 nhanced binding affinity for IGF-1R due to a synergistic effect of the Pro-Gln insertion and S29N poi

170 A synergistic effect of the two metals was found.

171 s differently, suggesting the potential of a synergistic effect of these proteases in improving the t

172 The synergistic effect of these two materials significantly

173 creased induction of apoptosis underlies the synergistic effect of this combination.

174 cardiovascular risk factors, especially the synergistic effect of thrombophilia with diabetes mellit

175 The synergistic effect of tPMET inhibition plus intracellula

176 The synergistic effect of two types of stereoactive lone-pai

177 ddition, the model shows that the unresolved synergistic effect of YAP/TAZ activity between the mecha

178 Combined, our data show a synergistic effect of zwitterionic and negatively charge

179 r structural engineering contributing to the synergistic effects of 2D morphology, amorphous structur

180 r SnTe-based material, which arises from the synergistic effects of Ag and In on the electronic struc

181 ikely that at least additive, or potentially synergistic effects of aging and HIV infection will be f

182 Our findings demonstrate the synergistic effects of calcipotriol and 5-FU treatment i

183 Importantly, an acidic pH reduced the synergistic effects of combinations of ASL antibacterial

184 ze, to our knowledge for the first time, the synergistic effects of combining different CPAs, and for

185 Synergistic effects of contact-killing and protein-repel

186 These initial results demonstrate how the synergistic effects of deploying multiple chemical mitig

187 0 unique diets; we quantified individual and synergistic effects of dietary macronutrients and the mi

188 Based on the synergistic effects of disparate sources of PCR bias, we

189 e and may promote understanding of potential synergistic effects of disparate stresses in this critic

190 Our results demonstrate separate and synergistic effects of diversity and eutrophication on s

191 l that the improved performance results from synergistic effects of enlarged open circuit voltage, su

192 l emphasis on preparative techniques and the synergistic effects of enzymes and MOFs.

193 ilability, and biomarkers to demonstrate the synergistic effects of foods are required.

194 ic community-to quantify the independent and synergistic effects of genetic, lifestyle, and other env

195 perazine N atoms of probe 1 is attributed to synergistic effects of H-bonding and electrostatic inter

196 ory and anti-apoptotic activities due to the synergistic effects of H2O2-scavenging boronic esters an

197 The synergistic effects of heterometals bestow CPM-200s with

198 The synergistic effects of I-CBP112 and current standard the

199 Furthermore, we evaluated the synergistic effects of itraconazole and paclitaxel using

200 ncreased FGF-21 mRNA levels, supporting that synergistic effects of lithium and VPA are mediated via

201 ammatory disorders, it is possible to detect synergistic effects of lung endothelium and epithelium o

202 is regulatory pattern strongly suggests that synergistic effects of miRNAs play critical roles in reg

203 In particular, we report synergistic effects of mitogen-activated protein kinase

204 To establish a method for exploring the synergistic effects of multiple compounds, we study the

205 In the study, we aimed to explore the synergistic effects of multiple risk factors on birth de

206 reatment for MDR-related tumors based on the synergistic effects of P-gp inhibition, enhanced endocyt

207 s and strong cross-programme links, enabling synergistic effects of public health policies that promo

208 Theoretical calculations reveal that the synergistic effects of Se vacancies and subsequent P dis

209 Our data suggest synergistic effects of sensory processing deficits, aber

210 s mammoth population died out because of the synergistic effects of shrinking island area and freshwa

211 Through the synergistic effects of size exclusion and charge repulsi

212 moke during their pregnancy, the potentially synergistic effects of smoking and pregnancy on the subg

213 ides an important tool for investigating the synergistic effects of spatially heterogeneous mechanica

214 The synergistic effects of Tat and LPS resulted in a reduced

215 these observed anomalous growth rates to the synergistic effects of the catalytic properties of Pt an

216 sensing performance can be attributed to the synergistic effects of the individual components in the

217 T calculations, which highlight the powerful synergistic effects of the Si:-->Ni moiety in the breaki

218 s lead to a good understanding of the stereo-synergistic effects of the sidearm.

219 roadband photodetection is attributed to the synergistic effects of the spatial nonuniform collective

220 dditionally, studies have yet to examine the synergistic effects of the various P gene products on pa

221 We achieved synergistic effects of these two hormones and mitigation

222 In preclinical studies, these synergistic effects of TSEC on ERalpha inhibition also s

223 The synergistic effects of ultrananoporosity and rich N/O co

224 In addition, synergistic effects of US on EC treatments were evaluate

225 otocol was designed on the basis of in vitro synergistic effects of valproic acid (VPA) and all-trans

226 The synergistic effects of vitamin D3 and vitamin K2 on bone

227 each of the CDC13A and CDC13B genes caused a synergistic effect on aberrant telomere elongation and t

228 ly, we show that depletion of Poltheta has a synergistic effect on cell survival in the absence of BR

229 Prevotella intermedia, resulted in a strong synergistic effect on complement.

230 The size and duration of the synergistic effect on Fe mobilization varied with ligand

231 by etoposide in AIRE-expressing cells had a synergistic effect on genes with low expression levels.

232 A synergistic effect on hD4R levels is noted when cytoplas

233 PI3K and Tiam1 to the apical membrane has a synergistic effect on membrane remodeling.

234 find that spr-5;met-2 double mutants have a synergistic effect on sterility, H3K4me2, and spermatoge

235 The synergistic effect on the ETP population was further cha

236 ay (ELISA) revealed that EC-TC contact has a synergistic effect on the expression of the cytokines in

237 utyrate and glycerol displayed a significant synergistic effect on the low temperature rescue of the

238 Parental asthma and recent SHS had a synergistic effect on the risk of asthma, the adjusted o

239 s, and end products of lipid oxidation had a synergistic effect on TLR2 activation.

240 ontrast, we did find consistent evidence for synergistic effects on (micro)environmental variation.

241 cted to identify which gene combinations had synergistic effects on clinical outcome in lung cancer s

242 Significant synergistic effects on E. coli presence and concentratio

243 n roots, mycorrhizal fungi and PGPR can have synergistic effects on growth and systemic priming of wh

244 orinostat/SAHA, the CARM1 inhibitor achieved synergistic effects on HIV-1 activation.

245 tigated, with several studies describing the synergistic effects on local and distant tumour control

246 rprisingly, we found no evidence of negative synergistic effects on Olympia oyster growth; rather, we

247 S1P and nSMase had synergistic effects on pulmonary vasoconstriction that i

248 Some miRNAs appeared to have synergistic effects on shared targets.

249 etween MRTF-A and YAP are suggested by their synergistic effects on SRE.L- and TEAD-luciferase expres

250 sistent with this idea, LEC2 and ABI3 showed synergistic effects on the activation of the OLE1 promot

251 We hypothesized that alcohol and HCV have synergistic effects on the phenotype and function of mon

252 of Apt-Au NPs or BiOCl nanosheets, revealing synergistic effects on their activity.

253 If the environment and mutation load have synergistic effects on trait means, then the difference

254 n with sorafenib (100 mg/kg, orally) exerted synergistic effects on tumor suppression, as compared wi

255 h defects, and examine temporal trend of the synergistic effects over time.

256 kinase inhibitor to inhibit ERBB3/2 elicits synergistic effects, reducing cell viability by 90% and

257 ls (CSCs), the underlying mechanism for this synergistic effect remains incompletely understood.

258 in and AaIT (Na(+) channel blocker) produced synergistic effects, requiring 45% fewer spores to kill

259 extracts and a combination of both, showing synergistic effects (Sl:Ca, 1:1), were microencapsulated

260 y, mixtures of OH-PBDEs may show very strong synergistic effects, stressing the importance of further

261 hose of existing drugs and to deliver better synergistic effects than coadministration of a mixture o

262 ropic and metabotropic 5-HT receptors have a synergistic effect that is critical to both electrophysi

263 polyP-SNPs creates a substantially enhanced synergistic effect that lowers clotting time and increas

264 omedical approaches could create additive or synergistic effects that drive improved reduction of HIV

265 Data is emerging that these treatments have synergistic effects that might further increase therapeu

266 mixture of caftaric acid and SO2, there were synergistic effects that were more pronounced with the F

267 on of nonlytic IL-2/Fc and TGF-beta/Fc had a synergistic effect to promote engraftment and resulted i

268 ACCT demonstrates synergistic effects to enhance cardiac regeneration and

269 AR3A, and, especially HC84.26, demonstrated synergistic effects towards the majority of the HCVcc's

270 ation of the experiment; for DMA, an initial synergistic effect turned into an antagonistic effect af

271 ere all important, with two combinations for synergistic effects, two for antagonistic, and five for

272 and TAG to 3.8% dry weight, demonstrating a synergistic effect upon combining these mutations.

273 The magnitude of the synergistic effect varied between 1.06 and 1.24 dependin

274 This synergistic effect was evident only when the two vaccine

275 mutants were similarly impaired, a dramatic synergistic effect was found for the double mutant acros

276 For HBED, macroscopically the synergistic effect was hidden due to the inhibitory effe

277 A synergistic effect was observed between aminophylline an

278 A synergistic effect was observed between the eugenol and

279 ssociation of UTIs and young maternal age, a synergistic effect was observed.

280 g metals; and for esculetin and citrate, the synergistic effect was temporary (less than 24 h).

281 This synergistic effect was validated in vivo using an HCV-in

282 Synergistic effects were observed between (beta-carotene

283 Synergistic effects were observed in multiple cell lines

284 In addition, pevonedistat exhibited additive/synergistic effects when combined with cytarabine, benda

285 -dependently induced chemotaxis of MSCs with synergistic effects when combined.

286 tin were the principal constituents that had synergistic effects when used at the optimal ratio.

287 Our data revealed complex synergistic effects, whereby tN-Ras binding was higher o

288 ion of RNO and dexamethasone showed additive/synergistic effects, which were consistent with the reve

289 inhibitors targeting histone methylation for synergistic effects while still maintaining selectivity.

290 apacity, less cytotoxicity, and a remarkable synergistic effect with anti-TB drugs both in vitro and

291 ating that hGH may exert a complementary and synergistic effect with c-Mpl ligands on thrombopoiesis.

292 low" protein intake or 2) dietary protein's synergistic effect with Ca+/-D intake on bone health out

293 Notably, glutamine starvation has a synergistic effect with cisplatin, a component of the cu

294 ruses, in vitro drug resistance barrier, and synergistic effect with oseltamivir.

295 e bacteria is still not clarified, even if a synergistic effect with the bisguanidine chlorhexidine o

296 ojunction layer, which is found to promote a synergistic effect with the GQD-incorporated hole extrac

297 In particular, MMAR showed a strong synergistic effect with the PR-D212N,F234S double mutant

298 e pleuromutilin derivative 1 displays strong synergistic effects with doxycycline in a wide range of

299 They also exhibit strong synergistic effects with standard chemotherapy.

300 properties of each component, or even with a synergistic effect, would present improved characteristi