ライフサイエンスコーパス: synergize

1 peripheral and central OT releases match and synergize.

2 inically used proteasome inhibitors strongly synergize ART activity against both sensitive and resist

3 Mechanistically, corticosterone and CRH synergized at the spine-actin regulator RhoA, promoting

4 Cyt1Aa is lipophilic and synergizes Bti Cry proteins by increasing midgut binding

5 The cytokines functionally synergize, but their production kinetics widely differ.

6 Anti-CD27 and anti-PD-L1 synergized by downregulating the expression of multiple

7 based photoreception in the large LNvs while synergizing CRY-mediated photoreception in the small LNv

8 docrine signaling by blocking, mimicking, or synergizing endogenous hormones through direct receptor

9 le region 2 and constant region 1 antibodies synergize for recognition of virus-infected cells, infec

10 vantages of both types of compounds could be synergized if low molecular weight molecules could be tr

11 ray of lignin transformation phenotypes that synergize in combination.

12 In vitro, MG and TNF-alpha were shown to synergize in promoting endothelial cell death, which was

13 w opposite structural effects on F-actin yet synergize in promoting release of phalloidin from filame

14 bind weakly to importin alpha, the two NLSs synergize in the context of the full length NP to confer

15 , demonstrating that adjacent VASP molecules synergize in the elongation of a single filament.

16 c-Abl and HIPK2 synergized in activating p53 on apoptotic promoters in a

17 ggered LMP and 2DG-mediated glycolysis block synergized in inducing rapid ATP depletion, mitochondria

18 ABT-263/ABT199 with the CDK7 inhibitor THZ1 synergized in producing growth inhibition and apoptosis

19 ions of CF-301 with vancomycin or daptomycin synergized in vitro and increased survival significantly

20 ator-activated receptor alpha (PPARalpha) to synergize its transcriptional activities in hepatic gluc

21 a key component of NADPH synthesis, potently synergizes MB activity.

22 Overall, SUSP4 appears to use two synergizing modules, the p53 rescue motif described here

23 The combination of PET and MR imaging synergizes molecular and morphologic information, allowi

24 The approach combined and synergized normally disparate vector properties and tool

25 egic plans of both august bodies converge to synergize on population lung health.

26 e demonstrated that small molecular phenamil synergized osteogenesis and bone formation with BMP2 in

27 actly how membrane curvature and composition synergize remains largely unexplored.

28 iver combinatorial adjuvants and selectively synergize specific types of immune responses for vaccine

29 development for the treatment of ABC DLBCL, synergized strongly with BET inhibitors in killing ABC D

30 icts DLBCL survival in vitro and in vivo and synergizes strongly with the Bruton's tyrosine kinase in

31 nal analysis showed that N(1575)Y could also synergize the effect of L(1014)S/W, but not L(1014)G or

32 site structures that immobilize proteins can synergize the properties of both transducers and molecul

33 , whereas its absence in hematopoietic cells synergized the level of dysbiosis.

34 In conclusion, DHA-VE synergized the main beneficial effects of two common nat

35 biofuel cell structure-based glucose sensor synergizes the advantages of both the glucose biosensor

36 ster-bomb"-like lipid-dendrimer nanoassembly synergizes the functions of its components and thereby e

37 hosphoinositide-3 kinase/mTOR pathway, which synergizes the induction of hypoxia-inducible factor (HI

38 nchronize their pharmacokinetic profiles and synergize their activities in solid tumor treatment, a n

39 in using wet spinning approaches in order to synergize their respective strength and cell interaction

40 ompetition between Fim1 and Adf1 for F-actin synergizes their activities, promoting rapid displacemen

41 d underscores the urgent need to realign and synergize these models to reflect evidence-based and out

42 tin remodeler [Brahma related gene 1 (BRG1)] synergize through the +9.5 site, conferring expression o

43 tions, mainly G:C-->T:A, and viral processes synergize to accelerate tumorigenesis, perhaps via infla

44 force and Wnt signaling act independently or synergize to activate beta-catenin signaling and cell di

45 We conclude that C. albicans and S. oralis synergize to activate host enzymes that cleave epithelia

46 that contact the promoter and each other and synergize to activate transcription in the atrioventricu

47 p27 short hairpin RNA and PPARalpha agonists synergize to ameliorate hepatosteatosis in mice fed a hi

48 novel ligand of murine and human STING could synergize to control local and distant tumors.

49 We examine how these oscillators synergize to control sniffing and whisking.

50 Coordinated glucagon and T3 actions synergize to correct hyperlipidemia, steatohepatitis, at

51 Rrp6 and Rrp47 synergize to create a composite and conserved surface gr

52 drug treatment-induced cellular changes, may synergize to create an environment leading to an increas

53 inducers that act by independent mechanisms synergize to decrease the reservoir as measured by viral

54 show how various levels of response kinetics synergize to dictate system sensitivity to different fea

55 ction could explain how obesity and IL-4 can synergize to exacerbate allergic inflammation.

56 circulating (high-density lipoprotein, HDL) synergize to facilitate Abeta transport across bioengine

57 (ethylene glycol) and sodium alginate, which synergize to form a hydrogel tougher than natural cartil

58 Whether pairwise loops synergize to form higher-order structures is still uncle

59 tially acting enzyme activators can potently synergize to give a significantly heightened biological

60 ese enzymes, the GH18 Cphy1799 and Cphy1800, synergize to hydrolyse chitin, a main component of the f

61 and Wnt-dependent beta-catenin stabilization synergize to increase beta-catenin-mediated transcriptio

62 is upregulated cytokines and chemokines that synergize to induce antigen-independent IFN-gamma produc

63 tenin and Activin/SMAD2,3 signaling pathways synergize to induce endodermal differentiation of human

64 n loss driven by the Hoxb13 regulatory locus synergize to induce genomic instability and aggressive p

65 cts, we demonstrated that these combinations synergize to induce HIV-1 transcription.

66 Nras(G12D) and Cbfbeta-SMMHC synergize to induce leukemia in mice in a cell-autonomou

67 These mechanisms are likely to synergize to maintain diploid cell populations.

68 hat the implementation of these efforts will synergize to markedly blunt the effect of the HIV pandem

69 nism dictating how curvature and composition synergize to modulate recruitment of lipidated proteins.

70 novel mechanism by which TLR and type I IFN synergize to promote monocyte/macrophage development fro

71 rthermore, myeloid and lymphoid cells likely synergize to promote obesity/T2D-associated periodontiti

72 naling pathways and upregulates Wnt7b, which synergize to promote PCC invasion, survival, and mitogen

73 eptor (IFN-gammaR) as essential signals that synergize to promote the development and appearance of t

74 r studies demonstrate that p62 and autophagy synergize to promote tumor growth, suggesting that inhib

75 al chaperone and Bcl-2 family inhibitors can synergize to safely degrade the growth of tumors recalci

76 lude that although Hif-1alpha and Hif-2alpha synergize to suppress the development of AML, they are n

77 strate how 2 distinct tolerance pathways can synergize to unleash autoimmunity and have implications

78 p53 and PTEN knockdown synergized to activate pro-inflammatory interleukin-6 (I

79 e impact, but rainfall and nutrient addition synergized to cause large increases in biomass, declines

80 ned with fully responsive fibroblasts likely synergized to contribute to psoriasis susceptibility in

81 ESP), at concentrations achieved clinically, synergized to increase Glo1 expression.

82 IL-4 and BAFF strongly synergized to promote B cell maturation, and IL-4 also r

83 the cell cycle downstream of TP53, and TGM2 synergized to promote oncogenic transformation.

84 r TIM-3 in tumor tissue, and TIM-3 and TIGIT synergized to suppress antitumor immune responses.

85 he combination of c-Met and PARP1 inhibitors synergized to suppress the growth of breast cancer cells

86 These two tracks have increasingly synergized to underscore the importance of cis-regulator

87 s indicated that inactivation of Rb and E2f8 synergizes to increase E2F2 binding to its target gene p

88 unique mechanism of two distinct inhibitors synergizing to inactivate the protease, providing a stru

89 omplementary strengths and weaknesses, which synergize when combined to sharpen gene expression bound

90 equencing (CAPP-Seq) by about threefold, and synergize when combined to yield approximately 15-fold i

91 aeruginosa isolates the activity that can be synergized when used in combination with other classes o

92 tanding selectivity over related enzymes and synergize with a cytidine analogue against leukemic cell

93 ory cytokines has also been reported and may synergize with adaptive signals to potentiate NK cell ac

94 and that targeting C/EBPbeta expression may synergize with anti-androgen or chemotherapy in eradicat

95 pidermal blistering (acantholysis), when AMA synergize with anti-Dsg antibodies.

96 effective maternal HIV-1 vaccine that could synergize with antiretroviral therapy (ART) to eliminate

97 f maternal vaccination strategies that could synergize with ART during pregnancy to achieve the elimi

98 loss of D2-family dopamine receptors did not synergize with bas-1 suppression of tauopathy phenotypes

99 rapeutic treatment may have the potential to synergize with beta-lapachone treatment, creating unique

100 y searched for targeted therapies that might synergize with CDK4/6 inhibition in this setting.

101 vaccines and cellular immunotherapies could synergize with checkpoint blockade, but which of these t

102 nostic factor in breast cancer, and TILs may synergize with chemotherapy and immune checkpoint inhibi

103 Thus, CD27-mediated costimulation can synergize with coinhibitory checkpoint blockade to switc

104 al community of "new experts" that over time synergize with computational efforts to accelerate scien

105 We hypothesized that MTAs synergize with DDAs by interfering with trafficking of D

106 However, whether protein immunizations synergize with DNA prime-viral vector boosts to enhance

107 The selective WEE1 inhibitor MK-1775 synergize with DNA-damaging agent to inhibit cancer cell

108 ubicin-treated cells and that ganetespib may synergize with doxorubicin in part through the downregul

109 dependent effects on dynein motility and can synergize with dynactin to enhance processive dynein mov

110 E84 and E195 synergize with E70, previously shown to be active in mos

111 y that decreased colonization resistance may synergize with effects of malaria on systemic immunity t

112 These IL-6 cytokines can then synergize with ER stress in astrocytes to drive inflamma

113 epressant (AD) paroxetine (PAR) functionally synergize with FKBP51, as revealed by reporter gene and

114 gesting that dioxin-induced AHR pathways can synergize with gene mutations to inhibit MAP3K1 signalin

115 ts voltage-gated l-type Ca(2+) channels that synergize with GluN2A-containing NMDA receptors to drive

116 H3 tail had little effect, but were able to synergize with H4 tail acetylation mimics to further inc

117 investigated whether T cell-recruiting bsAbs synergize with hypofractionated tumor radiotherapy (hRT)

118 Based on the ability of GPCR agonists to synergize with IGFs to enhance gene expression in other

119 nd VEGF signaling pathways, and how they may synergize with immunomodulatory antibodies that target P

120 In this context, insulin can synergize with inflammation to promote proliferation, su

121 at certain drugs that act on aneuploid cells synergize with inhibitors of Aurora B to inhibit colony

122 er a CB1 positive allosteric modulator would synergize with inhibitors of endocannabinoid deactivatio

123 We report that SMCs synergize with innate immune stimulants and immune check

124 els of tumor necrosis factor (TNF)-alpha may synergize with insulin in signaling inflammation and car

125 Tat and Nef regulate the KSHV life cycle and synergize with KSHV oncogenes to promote angiogenesis an

126 nterference is suppression of its ability to synergize with MDA5.

127 more, we show that MAIT cell-derived signals synergize with microbial stimuli to induce secretion of

128 at inhibiting xC(-) transporter function may synergize with modalities that target the IGF-IR to heig

129 Additionally, while DCXs synergize with mTOR to stimulate axon regeneration, alon

130 ur finding that KDM1A inhibitors effectively synergize with multiple conventional as well as candidat

131 ction with IFN-inducing viruses, are able to synergize with New World Leishmania parasites in both pr

132 entify highly active antileukemic drugs that synergize with NOTCH1 inhibition in T-ALL.

133 sed by melanoma cells to identify those that synergize with or cause resistance to checkpoint blockad

134 a docking/interacting site that allows it to synergize with other EFs to promote RNAPII transcription

135 By blocking schizont egress, PfSEA-1 may synergize with other vaccines targeting hepatocyte and R

136 normally fail to control HIV-1 infection can synergize with passively administered bNAbs by preventin

137 HDACIs also synergize with phosphatidylinositol 3-kinase inhibitors

138 tially ordered structures, some of which may synergize with photon absorption and act catalytically.

139 ecule inhibitors of the PIM2 and ZAK kinases synergize with PI3K inhibition.

140 treatment, or a novel therapeutic target to synergize with PI3K-AKT inhibition in RCC treatment.

141 ntly, these isoform-targeted HDAC inhibitors synergize with PKC modulators, namely bryostatin-1 analo

142 Subsets of leukocytes synergize with regenerative growth factors to promote he

143 screened for clinically used drugs that can synergize with RG7787.

144 ylation, suggesting that KRAS mutation might synergize with SNORD50A and SNORD50B loss in cancer.

145 diated Hg reduction and oxidation compete or synergize with sorption, thus affecting the production o

146 as to identify other FDA-approved drugs that synergize with statins to further enhance the anticancer

147 of ion homoeostasis in cancer cells can thus synergize with targeted agents to promote tumour regress

148 regulating motif is not required for PAR2 to synergize with TGF-beta1 to promote cell motility.

149 mily may induce responses that antagonize or synergize with the activities of another family, cell fa

150 small molecules and identified several that synergize with the antibiotic trimethoprim and/or sulfam

151 also mediate transcriptional changes and can synergize with the ER to regulate cell function.

152 Moreover, anti-angiogenic therapies synergize with the first-line anti-tubercular antibiotic

153 lele backgrounds, identifying mutations that synergize with the minor allele.

154 yST to block myoblast differentiation and to synergize with the phosphodiesterase inhibitor isobutylm

155 ghlights how regulated protein secretion can synergize with tissue movement to build a polarized BM a

156 est that higher concentrations of BMP9/BMP10 synergize with TNFalpha to induce the up-regulation of e

157 Therefore, we reasoned that PL would synergize with TRAIL to stimulate potent apoptosis in ca

158 VEGFA, TNF-alpha and IL-6 promote and likely synergize with VEGFA in corneal lymphangiogenesis during

159 ncy via indirect mechanisms, and it may also synergize with Z and R to enhance lytic replication thro

160 In vitro, 1599 synergized with 11 drugs from 6 antibiotic classes.

161 inhibitor of T cell stimulation via the TCR, synergized with abatacept to inhibit T cell activation.

162 nd CDK9 inhibitors including dinaciclib that synergized with ABT-263 through downregulation of MCL-1.

163 Finally, NOD2 synergized with additional PRRs to increase Twist1 and T

164 Consistent with the in vivo data, AngII synergized with BAFF to induce IL-10 production by B cel

165 ath of Myc-induced murine lymphoma cells and synergized with BETi.

166 MTS assay revealed that ganetespib synergized with both doxorubicin and etoposide, two topo

167 tations, partial inhibition of Akt signaling synergized with camptothecin or etoposide, but higher A-

168 However, the SAA fragments potently synergized with CCL3 to induce monocyte migration and wi

169 We found that TSLP synergized with CD40 ligand to promote DC activation and

170 Further studies revealed that IL17A synergized with commensal bacteria to trigger Ikkepsilon

171 ected in conventional screens, and yet, they synergized with conventional transcriptional activators.

172 Furthermore, GMF synergized with Coronin in inhibiting actin nucleation b

173 ion and coinhibitory markers on T cells, and synergized with CTLA4-Ig to promote long-term acceptance

174 Here, we demonstrate that CXCL14 synergized with CXCL12 in the induction of chemokine res

175 KDM5i synergized with DAC to reduce the viability of luminal b

176 ) cells to PKC412; conversely, KIT depletion synergized with decitabine in eliminating decitabine(R).

177 tion, and their independent suppression also synergized with DEX.

178 IL-4 synergized with DG172 to shift the differentiation from

179 In multiple cancer cell populations, ONC201 synergized with diverse drug classes, including the mult

180 ibition in combination with T cell depletion synergized with either CTLA-4Ig administration or subopt

181 Storage at 4 degrees C synergized with encapsulation in preventing degradation

182 and a small-molecule AMPK inhibitor strongly synergized with glucocorticoids, identifying TXNIP, CNR2

183 Checkpoint blockade strongly synergized with heterologous vaccination to enhance over

184 eting BCL2 by the specific inhibitor ABT-199 synergized with ibrutinib in inhibiting growth of both i

185 NOD2 synergized with IFN-gamma to induce CXCL9 and CXCL10 sec

186 Notably, checkpoint blockade therapy synergized with IL12 to fully enable tumor control by NK

187 ck loop of macrophage-derived IL-10 and this synergized with inhibition of the JNK pathway for limiti

188 Activation of Mertk synergized with interferon-beta to tighten cell junction

189 Here we show that growth factor FGF2 synergized with interleukin-17 (IL-17) to induce genes f

190 topic expression of Nef in endothelial cells synergized with K1 to facilitate vascular tube formation

191 Mechanistically, we showed that Tat synergized with K1 to induce the expression of miR-891a-

192 at PRIMA-1(Met) inhibited myeloma growth and synergized with L-buthionine sulphoximine in vivo.

193 oughput screen and identified molecules that synergized with low concentration of IFNgamma.

194 rimary macrophages a subset of rocaglates 1) synergized with low concentrations of IFNgamma in stimul

195 models, pharmacologic CK1alpha inactivation synergized with lysosomotropic agents to inhibit growth

196 SBI-0206965 greatly synergized with mechanistic target of rapamycin (mTOR) i

197 activate PI3K selectively in T lymphocytes, synergized with MEK inhibitors in vivo to elicit potent

198 ABZ had negligible effects on Wolbachia but synergized with minocycline or rifampicin (RIF) to deple

199 and apoptosis in pancreatic cancer cells and synergized with minocycline to yield a robust mitochondr

200 The Salmonella cytochrome bd-II oxidase synergized with nitrate reductases to drive luminal expa

201 These effects synergized with other lytic inducers of EBV, including t

202 Further, deletion of PUMA synergized with PD treatment for even greater intestinal

203 synthetic lethal screen, pan-PI3K inhibition synergized with PDK1 inhibition to suppress melanoma gro

204 Strikingly, AMPK inhibition synergized with physiological metabolic stress caused by

205 printhead consisting of bundled capillaries synergized with programmed movement of the motorized sta

206 ancer cells with a miR-139-5p mimic strongly synergized with radiation both in vitro and in vivo, res

207 However, in both B-ALL and AML, TRC105 synergized with reduced intensity myeloablation to inhib

208 The competitive inhibitor of NQO1 dicoumarol synergized with rifampin to promote intracellular killin

209 downstream effector for BET degraders, which synergized with small-molecule inhibitors of BCL-xL in t

210 In both lines of mice, adjunct 5-HTP SR synergized with SSRI to elevate 5-HTExt beyond the SSRI

211 ith altered dendritic cell (DC) function and synergized with T cell functional defects to promote exp

212 Accordingly, 5-NIdR synergized with temozolomide to increase apoptosis of tu

213 ibitor PET-16 reduced levels of mutant BRAF, synergized with the BRAF inhibitor PLX4032 in vitro, and

214 suppressor cells in the premetastatic niche, synergized with the depletion of AM in preventing metast

215 Notably, both miRNAs synergized with the frontline colorectal cancer chemothe

216 VISTA blockade synergized with the vaccine to effectively impair the gr

217 ent, at higher concentrations both cytokines synergized with tumor necrosis factor-alpha (TNFalpha) t

218 that a nontoxic dose of IL-2 immunocytokine synergized with tumor-specific antibody to significantly

219 of Nef in endothelial cells and fibroblasts synergized with vIL-6 to promote vascular tube formation

220 EK/ERK signalling module and SMYD3 depletion synergizes with a MEK inhibitor to block Ras-driven tumo

221 bset of glucose-deprived melanoma cells, but synergizes with acetate to support cell survival.

222 s (LPEs), elicits no response on its own but synergizes with activating sulfonolipid rosette-inducing

223 ssion and stabilize beta-catenin, which then synergizes with Activin-induced SMADs to activate a subs

224 Further, it synergizes with AGPs to enhance the release of TNF-alpha

225 onal evidence that the Notch1 signaling axis synergizes with alternative pathways in promoting metast

226 c239) replication, and that this restriction synergizes with an intrinsic resistance to infection pre

227 ical data demonstrate that inhibition of COX synergizes with anti-PD-1 blockade in inducing eradicati

228 A4 synergizes with anti-PD-L1, but not anti-CTLA4, therapy

229 etic abnormalities, and (2) in Ph(+) CML, it synergizes with BCR-ABL signaling, reducing the efficacy

230 ptor (TLR) signaling pathways in macrophages synergizes with blocking CD47 on tumor cells to enhance

231 ostatin-1 (Nec-1) and necrosulfonamide (NSA) synergizes with BSO and auranofin in killing TSC-deficie

232 directly binds to IL-4 promoter regions and synergizes with c-Maf to positively regulate IL-4 expres

233 The hyperpolarization signal also synergizes with canonical reprogramming factors (POU and

234 g the activation of the Slt2 MAP kinase, and synergizes with cell wall stressors such as micafungin a

235 PI3Kgamma synergizes with checkpoint inhibitor therapy to promote

236 urthermore, a small-molecule STAT3 inhibitor synergizes with CHOP to trigger oxidative stress and kil

237 ppresses proliferation of leukemia cells and synergizes with CK2 inhibition.

238 skin transplant model, the addition of IL-2 synergizes with CNIs treatment, promoting intragraft acc

239 of the post-transcriptional suppressor DND1 synergizes with concurrent transcriptional changes to en

240 NSC59984 synergizes with CPT11 to induce cell death in mutant p53

241 Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR

242 escence-associated heterochromatic foci that synergizes with DNA methylation to silence tumor-suppres

243 Our results demonstrate that p53(-/-) synergizes with enhanced oncogenic Nras signaling to tra

244 ribose) polymerase (PARP) inhibitor olaparib synergizes with GLS1 inhibitors to suppress the growth o

245 Furthermore, we found that iguratimod synergizes with glucocorticoids in attenuating experimen

246 ranscription through either of these methods synergizes with HDAC inhibition, and DIPG cells resistan

247 LOX in colorectal cancer synergizes with hypoxia-inducible factor-1 (HIF-1) to pr

248 Thus, NOD2 synergizes with IFN-gamma to promote CXCL9 and CXCL10 ex

249 ed for IL-17A secretion by ILCs in vitro but synergizes with IL-17A to induce the expression of neutr

250 e associated with Th2-mediated inflammation, synergizes with IL-4 in inducing IL-31 secretion.

251 Importantly, we established that IL-13 synergizes with IL-4 in inhibiting CTCL cell growth and

252 Importantly, UV-HSV-1 synergizes with interleukin-15 (IL-15) and IL-2 in induc

253 Moreover calcitriol strongly synergizes with itraconazole (ITZ) in Smo inhibition, wh

254 he histone deacetylase (HDAC) inhibitor SAHA synergizes with JQ1 to augment cell death and more poten

255 An epigenetic inhibitor suppressing c-Myc synergizes with lapatinib to suppress cancer growth in v

256 te that expression of a dominant active PI3K synergizes with loss of APC activity resulting in a dram

257 present evidence that loss of Foxa2 and Cdx2 synergizes with loss of Nkx2-1 to fully activate the met

258 ion, we demonstrate that PSGR overexpression synergizes with loss of PTEN to accelerate prostate canc

259 ytated FetA bind to LPS, but only the former synergizes with LPS and grass pollen or mite allergens t

260 It synergizes with metabolic reprogramming of T cells to ac

261 recognition motif (RRM) domains of hnRNP L, synergizes with miR-297, reduces VEGFA mRNA translation,

262 A systemic loss of Parkin synergizes with mitochondrial dysfunction causing dopami

263 These data indicate that Runx2 synergizes with Msx1 to drive tooth morphogenesis throug

264 Chronic activation of Notch1 synergizes with multiple oncogenic pathways altered in e

265 ter-mediated expression of LMO1 in zebrafish synergizes with MYCN to increase the proliferation of hy

266 dent activation of the local innate response synergizes with noncognate T cells to restrict bacterial

267 IL-17A both directly induces and synergizes with other cytokines to promote autoimmune ti

268 es with miR396-mediated AtSVP mRNA decay and synergizes with other effects (e.g. MADS box transcripti

269 signaling in a shallow PDGF gradient, but it synergizes with other feedback mechanisms to enhance amp

270 We also review how TRIM21 synergizes with other innate immune receptors to promote

271 Here we show that RSPO3 antagonism synergizes with paclitaxel based chemotherapies in patie

272 mma independently of PGC-1 coactivators, yet synergizes with PGC-1alpha to induce the thermogenic pro

273 servations identify targets whose inhibition synergizes with PI3K inhibitors and nominate potential c

274 s demonstrate in neonatal mice how gut flora synergizes with poly(I:C) to elicit protective intestina

275 o Gq- and Gi-coupled receptor signaling that synergizes with primary activation signals to maximally

276 ted system, demonstrate that the Shu complex synergizes with Rad55-Rad57 and Rad52 to promote nucleat

277 Here the rigidity of cross-linked collagen synergizes with retinoids in the osteogenesis of human m

278 nce factor, ROP17, which forms a complex and synergizes with ROP5/ROP18 to fully disable the IRG syst

279 We find that activated Src synergizes with Runx1 to activate a Runx1 luciferase rep

280 is stimulated by high membrane curvature and synergizes with SNX9 BAR domain binding in a process we

281 We also find that the acetyltransferase Gcn5 synergizes with Spt3 to promote global transcription and

282 N8237, which is currently in clinical trial, synergizes with tamoxifen and overcomes tamoxifen resist

283 pen-state sodium channel inactivation, which synergizes with temperature-dependent enhancement of ina

284 Jasplakinolide-induced actin polymerization synergizes with TGFbeta to facilitate MRTF-dependent Nox

285 Coco synergizes with TGFbeta1 in both cell culture and Xenopu

286 ngly, G4C2 transcript-mediated neurotoxicity synergizes with that of PR aggregates, suggesting conver

287 Here, we show that DNMT3A loss synergizes with the FLT3 internal tandem duplication in

288 e PPAR-alpha agonists GW7647 and fenofibrate synergizes with the glucocorticoid receptor (GR) to prom

289 ntagonism of IRF-1 is a novel mechanism that synergizes with the noted ability of flaviviruses to sup

290 rthermore, combining miR-137 and antimiR-10b synergizes with the receptor inhibitory function of apta

291 , the mechanism through which the microbiota synergizes with these etiologic factors to promote CRC i

292 Additionally, physapubescin synergizes with TNF-related apoptosis-inducing ligand (T

293 rference with the CD47-SIRPalpha interaction synergizes with tumor-specific monoclonal antibodies to

294 Velcro-CD47 synergizes with tumor-specific monoclonal antibodies to

295 Mechanistic studies indicated that Nef synergizes with vIL-6 to enhance angiogenesis and tumori

296 rther analysis showed that IFN-beta alone or synergizing with CD95 blocked the activation of lytic sw

297 SC responses to local acetylcholine release, synergizing with fibroblast growth factor receptor activ

298 Screening for activators capable of synergizing with HMGN1 in activating DC identified R848.

299 with tau, preserving tau protein levels and synergizing with it to assemble MTs.

300 that anti-TAA mAbs are capable of profoundly synergizing with T cell-directed immunotherapies such as