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1 received bilateral orthotopic injections of syngeneic 67NR, 4T07, or 4T1cells (1 x 10(5) cells per i
4 ed ASNase efficacy in mice transplanted with syngeneic ALL cells and, like in humans, without affecti
8 In vivo, cell engraftment was similar in the syngeneic and allogeneic groups 1 week and 3 weeks after
9 first days after embryo implantation in both syngeneic and allogeneic matings; express the markers of
11 B-cell reconstitution is abrogated in both syngeneic and allogeneic transplantation using Treg-depl
12 t of an antibody-mediated CD47 blockade in a syngeneic and an allogeneic DCD rat kidney transplant mo
13 expression of PD-L1, which was confirmed in syngeneic and genetically engineered mouse models of lun
14 iferated more in response to Ag presented by syngeneic APC than the same T cell subset from healthy a
15 ce, C1q-deficient (C1qa(-/-)) mice bearing a syngeneic B16 melanoma exhibit a slower tumour growth an
17 udy, we show that the growth of transplanted syngeneic B16F10 melanoma or Lewis lung carcinoma cells
20 e immunized against platelets from wild-type syngeneic BALB/c (CD61(+)/H-2(d)), allogeneic C57BL/6 (C
21 n of a GR9-B11 mouse fibrosarcoma clone into syngeneic BALB/c mice, all animals remained free of spon
26 ansfer of T cells from transplanted nudes to syngeneic black-coated RAG(-/-) recipients caused progre
27 though CMV infection was self-limiting after syngeneic BMT, in the presence of GVHD after allogeneic
32 on analyses combined with in vivo studies in syngeneic breast cancer models demonstrate the participa
34 use HCC cells (Hepa1-6) were inoculated into syngeneic C57BL/6 mice, intratumoral injection of adenov
35 ies of the promising cationic amphiphiles in syngeneic C57BL/6J mice under prophylactic settings.
36 injected B16rho(0) mouse melanoma cells into syngeneic C57BL/6N(su9-DsRed2) mice that express red flu
37 We demonstrated that both allogeneic and syngeneic CAR T cells show initial expansion as effector
38 y of diabetes reversal of allogeneic but not syngeneic CC islets was lower than that of naked islets,
41 a diminished 5-FU therapeutic response in a syngeneic colorectal tumor model consistent with increas
42 the bacterial population dynamics in ectopic syngeneic colorectal tumours in mice via a luminescent r
46 ed inflammation when they were recipients of syngeneic corneal transplants but also exhibited signifi
52 ion of hapten conjugated to self-antigens of syngeneic erythrocytes and subsequent contact immunizati
53 specific STAT3-knockdown postnatal mice-plus syngeneic fibroblast cell-transplant models-we demonstra
57 B signaling (p65) in myeloid cells inhibited syngeneic glioblastoma (GBM) through decreased CD45 infi
60 rates that resistance to MYXV virotherapy in syngeneic glioma models involves a multifaceted cellular
64 he airway epithelium was mostly preserved in syngeneic grafts, mostly destroyed in the KCa3.1 and TRA
65 the survival or histology of DST/MR1-treated syngeneic heart grafts, the latter indicating that persi
66 cytomegalovirus (anti-MCMV) responses after syngeneic hematopoietic stem cell transplantation (HSCT)
67 Compound 3c almost eliminated the growth of syngeneic hepatocellular carcinoma in Balb/c mice, sugge
69 ated events in the liver after transplanting syngeneic hepatocytes into dipeptidyl peptidase IV-defic
73 developed murine models of this disease, in syngeneic hosts as well as in nonobese diabetic/severe c
74 51 days), and old (736 days) C57BL/6 mice as syngeneic hosts for engraftment of Lewis lung cancer to
79 ion gp96-Ig within 2 weeks of T cell-replete syngeneic HSCT led to cross-presentation and increased s
81 trate that human induced Treg cells suppress syngeneic human ILC2s through ICOSL to control airway in
83 phatic drainage from murine B16 melanomas in syngeneic, immune-competent C57Bl/6 mice is associated w
84 ompared with an otherwise identical IgG in a syngeneic immunocompetent animal, and we identify TNFalp
85 y, and immunosuppressive microenvironment in syngeneic immunocompetent mice and should prove useful f
86 otopic malignant gliomas were established in syngeneic immunocompetent mice and then treated with den
91 T cell proliferation in vitro, rejection of syngeneic iPSC-derived EBs/tissue-specific cells (TSCs)
94 ockade leads to a significant improvement of syngeneic islet engraftment and of allogeneic islet graf
98 etic C57BL/6 mice were transplanted with 350 syngeneic islets through the portal vein and treated onc
99 of suboptimal islet transplants of 50 or 125 syngeneic islets to achieve glycemic control in STZ-indu
100 plantation of a marginal mass (50 islets) of syngeneic islets treated with nanoparticle conjugates ta
101 xpression of TGF-beta prevented rejection of syngeneic islets, that there was reduction of dendritic
103 iatrogenic interference), allogeneic but not syngeneic leukocytes could induce a rapid (after 1 d) ac
105 acity in NFAT5-deficient macrophages against syngeneic Lewis lung carcinoma and ID8 ovarian carcinoma
107 used systemically to treat established BCL1 syngeneic lymphoma, and therapy is lost when using a mou
108 male mice of inbred strain CBA do not reject syngeneic male skin grafts even though they mount a T-ce
109 R4 blockade resulted in significantly better syngeneic marginal mass islet engraftment and in indefin
110 for mAb-induced therapy of both subcutaneous syngeneic melanoma and human breast cancer xenografts.
111 lidated a mouse model of endometriosis using syngeneic menstrual endometrial tissue introduced into t
113 cle for doxorubicin delivery (CP-Dox) in the syngeneic metastatic murine models 4T1 and Lewis lung ca
117 ailed to grow when transplanted into normal, syngeneic mice but grew progressively in immunosuppresse
118 promoted the tumor growth in immunocompetent syngeneic mice but not in immunocompromised or Treg cell
120 tly, we showed that generation of tumours in syngeneic mice by cells devoid of mitochondrial (mt) DNA
124 r accomplishing robust anti-PDAC immunity in syngeneic mice through the induction of immunogenic cell
125 coma cells were injected into the spleens of syngeneic mice to isolate tumour sub-populations that co
126 ts in complete FC-muMCL1 tumor regression in syngeneic mice via NK- and T-cell-dependent mechanisms.
127 cle or PAHSA and splenic CD4(+) T cells from syngeneic mice were co-cultured to assess antigen presen
128 lls distributed predominantly to the lung of syngeneic mice, a frequent site of breast cancer metasta
129 d for tumor cells to grow and metastasize in syngeneic mice, a surprising finding given that other in
130 line recapitulated mast cell recruitment in syngeneic mice, demonstrating that this cell state can d
131 e tumorigenesis and lung metastasis model in syngeneic mice, depletion of LKB1 markedly increased tum
133 cells were transplanted into 3-day wounds of syngeneic mice, only CD206(+)/CD301b(+) macrophages sign
135 the growth of transplantable B16 melanoma in syngeneic mice, which is accompanied by enhanced antitum
142 tion-induced (10 Gy) tumor growth delay in a syngeneic model (C3H) but not immunosuppressed (Nu/Nu) s
144 eatment in immune competent mice utilizing a syngeneic model of mammary tumor growth in FVB mice.
148 We previously showed that ID8, a widely-used syngeneic model of ovarian cancer, lacked any of the fre
150 culminating in improvement in survival in a syngeneic model of ovarian peritoneal carcinomatosis.
152 tastatic gene signature' derived from murine syngeneic model predicts poor patient survival in the ma
154 apparent body weight loss in the murine CT26 syngeneic model, after oral administration of 400 mg/kg.
157 I-402257 reduced MM growth in an orthotopic, syngeneic model, when used as a single agent, and more s
158 ls rendered protection against melanoma in a syngeneic model, with decreased expression of PD-L1 and
160 ompared these activities using two different syngeneic models for normal and oncogene-transformed hum
161 d (AP20187) triggered apoptosis in 2 in vivo syngeneic models of bone tumor growth in which apoptosis
165 n mouse triple-negative breast cancer (TNBC) syngeneic models with a TGI (tumor growth inhibition) of
167 e compared more than 3700 compounds in three syngeneic mouse embryonic stem cell (mESC) lines: htt(-/
168 d in synergistic activity in two independent syngeneic mouse glioma models by promoting migration of
169 ortalized normal human astrocytes (NHAs) and syngeneic mouse glioma models, the introduction of mutan
170 tempered by evidence that undifferentiated, syngeneic mouse iPSCs are immunogenic upon transplantati
173 iability probe to immune cells isolated from syngeneic mouse MB49 bladder tumors, spleens, and tumor-
174 icle-encapsulated paclitaxel in subcutaneous syngeneic mouse melanoma and orthotopic xenograft lung c
175 istently, inflammatory MITF(low)/c-Jun(high) syngeneic mouse melanomas recruit myeloid immune cells i
176 high metastatic potential and an orthotopic syngeneic mouse model and in vitro using a CXCR2 small-m
177 mor activity of K145 was also confirmed in a syngeneic mouse model by implanting murine breast cancer
184 2 displayed potent efficacy in an aggressive syngeneic mouse model of multiple myeloma and prolonged
189 copal effects on both 4T1 and TUBO bilateral syngeneic mouse models further demonstrate that ZnP@pyro
192 eriments and mouse transcriptome analyses in syngeneic mouse models, we provide evidence that tumour-
199 n of 10(6) 5T33 mouse myeloma cells into the Syngeneic mouse strain C57BL/KaLwRij resulted in a rapid
200 nation with a clinical chemotherapeutic to a syngeneic mouse transplantation model of hepatic colorec
202 , and oral RA190 treatment retarded HPV16(+) syngeneic mouse tumor growth, without affecting spontane
205 survival improvements are achieved in three syngeneic mouse tumor models, including complete respons
207 lines, we performed a secondary screen in a syngeneic murine AML model driven by the MLL-AF9 oncogen
208 Dox-LTSLs were injected intravenously into a syngeneic murine breast cancer model (6 mg Dox/kg body w
215 ays, alternative methods of quantitation and syngeneic murine models have all led to an appreciation
216 in a physiologic setting, using preclinical, syngeneic murine models of hematologic malignancies and
218 esmoplastic human lung cancer xenografts and syngeneic murine pancreatic cancers in an immune-indepen
221 Tumor targeting of DAB4 was selective for syngeneic murine tumors and for human tumor xenografts o
223 ntraportally with 2500 ferucarbotran-labeled syngeneic (n=10) or allogeneic (n=12) islet equivalents
224 ls are similarly capable to polarize ex vivo syngeneic naive CD4(+) T cells toward a T-bet(+)IFN-gamm
225 oietic stem/progenitor cells into irradiated syngeneic or allogeneic young or aged recipients resulte
226 cts were elicited by 3'3'-cGAMP injection in syngeneic or immunodeficient mice grafted with multiple
227 oma (CTCL) lines, HH and Hut78, were used in syngeneic or standard NSG mouse models to demonstrate a
228 ses PDAC tumour cell growth in xenograft and syngeneic orthotopic animal models, and induces growth i
231 cells in the tumor microenvironment, using a syngeneic orthotopic mouse model of epithelial ovarian c
236 therapeutic response in an in vivo primary, syngeneic p53(null) claudin-low tumor model that is norm
237 H mutations in immune response, we created a syngeneic pair mouse model for mutant IDH1 (muIDH1) and
240 ction of Mobilan into subcutaneously growing syngeneic prostate tumors in immunocompetent hosts impro
242 ntly, low-purity (30:70% endocrine:exocrine) syngeneic rat islet preparations displayed function equi
246 widely on human ovarian tumors, along with a syngeneic rat tumor model expressing human FRalpha.
252 ed of autophagosomes (DRibbles) derived from syngeneic sarcomas could induce cross-reactive T-cell re
255 abeled TPP is continuously internalized into syngeneic, spontaneous, chemically/genetically induced a
256 microenvironment role of RAGE, we performed syngeneic studies with orthotopically injected breast ca
258 alloreactive T cells and was not observed in syngeneic T cells during homeostatic proliferation.
259 ultaneous transfer of genetically engineered syngeneic T cells expressing a chimeric antigen receptor
260 the role of BLT1 in antitumor immunity using syngeneic TC-1 cervical cancer model, and observed accel
261 fragmentation one week before engraftment of syngeneic TC1 or LL3 tumor cells and tumor analysis four
271 y (5 weeks) or at maturation (10 weeks) with syngeneic Trp53-null mammary tissue fragments and monito
272 two in vivo experimental systems: an ectopic syngeneic tumor (Lewis lung carcinoma) and an orthotopic
273 ytokine response and potent cytotoxicity for syngeneic tumor cells upon activation, as do human CD8al
274 -CpG-B could substantially protect mice from syngeneic tumor challenge, even after 4 mo of vaccinatio
276 pression within T cells is required to limit syngeneic tumor growth and promote IFNgamma production b
277 r-infiltrating CD8 expression in preclinical syngeneic tumor immunotherapy models including antigen-s
279 ement membrane, whereas its attenuation in a syngeneic tumor model resulted in reduced metastatic col
280 demonstrate that, in three different murine syngeneic tumor models (B16, SCC7, and 4T1), loss of the
281 ne cells to eliminate large tumor burdens in syngeneic tumor models and a genetically engineered mous
283 and inflammatory analysis of four additional syngeneic tumor models revealed that tumors can induce f
284 any of the effects of anti-mouse GITR mAb in syngeneic tumor models, decreasing both Treg numbers and
285 imaging inflammation in both xenogeneic and syngeneic tumor models, which resulted in detection of t
286 plete protection from tumor engraftment in a syngeneic tumor vaccine model, inhibited neutrophil extr
287 mes was similar to non-targeted liposomes in syngeneic tumor-bearing FVB mice and C-LPP liposomes red
288 The peptides were injected into rats with syngeneic tumors and mice with orthotopic or xenograft t
289 y was CD8 dependent and controlled growth of syngeneic tumors even when an adoptive immunotherapy was
290 C57BL6/KaLwRij mice bearing murine 5TGM1-GFP syngeneic tumors generated after intravenous injection v
291 ring peritoneal MKN-45P xenografts and CT-26 syngeneic tumors with IP linTT1-D(KLAKLAK)2-NWs resulted
292 tivity in orthotopic human tumor xenografts, syngeneic tumors, and a genetic model of pancreatic canc
294 munotargeting of xCT in mice challenged with syngeneic tumorsphere-derived cells delayed established
295 es and this correlated with no difference in syngeneic tumour growth between wild-type, Claudin 14-he
296 ma model SMA560 injected intracranially into syngeneic VM/Dk mice, analyzing animals at various posti
297 plantation (major histocompatibility complex syngeneic) was modeled by transplanting hearts from A-Tg
298 The stroke phenotype can be transferred to syngeneic wild-type mice via Tgfbr2(Myeko) bone marrow t
300 lls are directly implanted into the lungs of syngeneic WT mice or mice globally deficient in 5-LO (5-
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