ライフサイエンスコーパス: synovial cell

1 with catabolic processes in chondrocytes and synovial cells.

2 rticular chondrocytes and in fibroblast-like synovial cells.

3 ecruitment of EPCs and hyperproliferation of synovial cells.

4 uired for the prodestructive phenotype of RA synovial cells.

5 spontaneous release of cytokines by human RA synovial cells.

6 iate adherence to respiratory epithelial and synovial cells.

7 pulmonary artery endothelial cells and human synovial cells.

8 adherence to both respiratory epithelial and synovial cells.

9 popolysaccharide and in rheumatoid arthritis synovial cells.

10 expression and apoptosis are evident in the synovial cells.

11 odestructive invadosome-forming phenotype of synovial cells.

12 arkedly increase aFGF production by cultured synovial cells.

13 tion of calcium from intracellular stores in synovial cells.

14 require elimination of most or all activated synovial cells.

15 ilage boundary lubrication and inhibition of synovial cell adhesion.

16 iate adherence to respiratory epithelial and synovial cells and are selected against during invasive

17 ockade led to profound hyperproliferation of synovial cells and arthritogenic lymphocytes and heighte

18 Pro-Df was present in both synovial cells and chondrocytes of knees of WT and MASP1

19 cible hyaluronan-binding protein produced by synovial cells and chondrocytes that is present in synov

20 Interleukin 1 (IL-1), produced by both synovial cells and chondrocytes, plays a pivotal role in

21 ression of NKG2D and its ligands on human RA synovial cells and extended this finding to the paws of

22 itis are characterized by hyperactivation of synovial cells and hyperplasia of the synovial membrane.

23 stigated by Western blot analysis of primary synovial cells and immunohistochemical analysis of RA jo

24 igh levels of Fas are expressed on activated synovial cells and infiltrating leukocytes in the inflam

25 rylated VEGFR2 in articular chondrocytes and synovial cells and reduce levels of phosphorylated VEGFR

26 ient adherence to respiratory epithelial and synovial cells and that the number of pili expressed by

27 Of significance, Snail is overexpressed in synovial cells and tissues of CIA rats and RA patients,

28 els of FasL expression, induced apoptosis of synovial cells, and ameliorated collagen-induced arthrit

29 Keystones are inflammation, proliferation of synovial cells, and attachment and invasion of synovial

30 /-) donors and recipients, flow cytometry of synovial cells, and competition experiments measuring en

31 Mutant glenoid fossa, disc, synovial cells, and condyles displayed higher Hyaluronan

32 rg4) is secreted by surface chondrocytes and synovial cells, and has been shown to reduce friction in

33 in vitro, including monocytes, fibroblasts, synovial cells, and keratinocytes.

34 6), is induced in fibroblasts, chondrocytes, synovial cells, and mononuclear cells by the proinflamma

35 duced the expression of mdm2 by normal human synovial cells approximately 8-fold.

36 ndrocytes, genes for inflammatory factors in synovial cells, as well as pain-related proteins and ion

37 um correlates with the level of adherence to synovial cells but not with the level of adherence to re

38 trate that SAA is synergistically induced in synovial cells by interleukin (IL)-1 and IL-6 that are p

39 induces extracellular matrix degradation in synovial cells by repressing PTEN, resulting in increase

40 RNA variant of ADAMTS4 (ADAMTS4_v1) in human synovial cell cocultures obtained from patients with ost

41 SIGIRR was also overexpressed in synovial cells derived from RA patients.

42 an T cell subpopulations and fibroblast-like synovial cells (FLS) and examine its pathophysiologic si

43 (mRNA) expression in lymph node cells and in synovial cells from arthritic paws was measured by RNase

44 r matrix-degrading invadosomal structures by synovial cells from collagen-induced arthritis (CIA) rat

45 ytes and regulates inflammatory cytokines in synovial cells from human knee joints.

46 FcgammaRII F(ab')2 treatment of inflammatory synovial cells from RA patients inhibited ROS production

47 lpha transcripts were clearly evident in the synovial cells from the arthritic paws of IFNgamma-/- mi

48 FGF synthesis and release is a component of synovial cell growth that is markedly increased in RA.

49 he protection of surfaces and the control of synovial cell growth.

50 an and bovine chondrocytes, human and rabbit synovial cells, human epithelial cells, and rodent fibro

51 of functional cardiomyocytes from pathogenic synovial cells in RA patients through iPSC reprogramming

52 in human carcinomas and in chondrocytes and synovial cells in rheumatoid arthritis and osteoarthriti

53 ovial cadherin-11 determines the behavior of synovial cells in their proinflammatory and destructive

54 re used to examine the expression of aFGF by synovial cells in vitro.

55 that could account for the survival of CD95+ synovial cells in vivo.

56 jA (0-30 microM) in vitro to human blood and synovial cells increased production of LXA(4) (ELISA) 2-

57 findings suggest a novel mechanism by which synovial cells induce degradation of cartilage matrix th

58 ibition of synovial angiogenesis and reduced synovial cell infiltrate, pannus formation, and cartilag

59 t the interaction of viable spirochetes with synovial cells leads to the release of IL-8, which proba

60 ression vector was transfected into a rabbit synovial cell line (HIG-82) and a stably transfected cel

61 ction of the sIL-1R expression vector into a synovial cell line in vitro resulted in the appearance o

62 Acidic FGF was detected in all synovial cell lines during growth in vitro; however, syn

63 ransfected in vitro, and SV40-transformed RA synovial cell lines in SCID mice were transfected in viv

64 ucible specific inhibitor of apoptosis in RA synovial cell lines.

65 r bone was evident in any section containing synovial cell-loaded ceramic cubes that were harvested a

66 These synovial cells may contribute directly to the expansion

67 Adherent human rheumatoid synovial cells mobilize intracellular calcium via a P2U-

68 -1 protein was immunochemically localized to synovial cells of knees of WT mice with arthritis.

69 arthritis, with increased amounts present in synovial cells of WT mice with CAIA.

70 The activated synovial cells produce inflammatory cytokines and degrad

71 viously, we showed that iron increased human synovial cell proliferation and induced c-myc expression

72 was dependent on type I IFNs that inhibited synovial cell proliferation and inflammatory cytokine pr

73 in and assigned a histologic score (based on synovial cell proliferation, cartilage erosion, bone ero

74 nonuclear cells from HJD subjects stimulated synovial cell proliferation, which was blocked by a huma

75 emophilic synovitis and a marked increase in synovial cell proliferation.

76 hese cytokines induced phenotypic changes in synovial cells, promoting protrusion and increased cellu

77 In cocultures, IL-1RII(+) synovial cells released sIL-1RII, which in a paracrine f

78 One patient developed synovial cell sarcoma 8 years after therapy.

79 , which is expressed in 80% of patients with synovial cell sarcoma and approximately 25% of patients

80 s were observed in four of six patients with synovial cell sarcoma and five of 11 patients with melan

81 ies or a T-cell receptor against NY-ESO-1 in synovial cell sarcoma and melanoma.

82 ion in patients with metastatic melanoma and synovial cell sarcoma.

83 utic approach for patients with melanoma and synovial cell sarcoma.

84 g 18 months was observed in one patient with synovial cell sarcoma.

85 based prognostic variables characteristic of synovial cell sarcoma.

86 complement regulator can result in prolonged synovial cell surface binding and significant clinical b

87 joints are extremely low, and most activated synovial cells survive despite high levels of Fas expres

88 induce VEC growth directly and to stimulate synovial cells to produce endothelial growth factors.

89 es, human B cells, and human fibroblast-like synovial cells treated with SSRIs.

90 Isolated synovial cells were also tested for their chondrogenic p

91 Both RA and noninflammatory synovial cells were competent to release aFGF into the m

92 Fura-2-loaded synovial cells were screened for changes in cytosolic ca

93 Human synovial cells, when incubated with HJD sera, could elic

94 a have been well characterized in immune and synovial cells, which are known to be major contributors

95 Synovial explants and isolated synovial cells will undergo chondrogenesis when cultured