ライフサイエンスコーパス: synovial tissue

1 nd they promote leukocyte migration into the synovial tissue.

2 ontrols (P = 0.018) and were demonstrated in synovial tissue.

3 e assay and immunostaining were performed on synovial tissue.

4 they promote leukocyte trafficking into the synovial tissue.

5 topic germinal centres compared with diffuse synovial tissue.

6 ravasation through vascular endothelium into synovial tissue.

7 cyte behavior and function in organizing the synovial tissue.

8 lular DNA was detectable in various areas of synovial tissue.

9 be involved in leukocyte trafficking into RA synovial tissue.

10 s of patients with RA, compared with control synovial tissue.

11 essels (angiogenesis), when compared with DA synovial tissue.

12 on from RA compared with osteoarthritis (OA) synovial tissue.

13 n vitro marker of T cell accumulation within synovial tissue.

14 uced serum amyloid A expression in ileum and synovial tissue.

15 in the synovial fluid and macrophages in the synovial tissue.

16 was performed on RA and osteoarthritis (OA) synovial tissue.

17 he cells synthesizing MASP-1/3 and pro-FD in synovial tissue.

18 -3 production, and up-regulated TIMP-1 in RA synovial tissue.

19 SM was produced by macrophages in rheumatoid synovial tissue.

20 y 2-color immunohistochemistry of rheumatoid synovial tissue.

21 tants, was increased 10-fold in RA versus OA synovial tissue.

22 s but also exhibited reduced boron uptake in synovial tissue.

23 erosion, as well as less myeloperoxidase in synovial tissue.

24 mpare the expression of CCR7 and CCL21 in RA synovial tissue.

25 downstream mediator of TNFalpha signaling in synovial tissue.

26 via NF-kappaB or at the genomic level in the synovial tissue.

27 by collagenase digestion of two of the five synovial tissues.

28 n of PDGFR-alphabeta was also elevated in RA synovial tissues.

29 d in RA, were all abundantly expressed in RA synovial tissues.

30 s been observed in rheumatoid arthritis (RA) synovial tissues.

31 nonuclear and endothelial cells in RA and OA synovial tissues.

32 These findings also extended to synovial tissues.

33 sues from patients with RA but not in normal synovial tissues.

34 roblasts isolated from RA and osteoarthritis synovial tissues.

35 and three fz (fz2, 5, and 7) isoforms in RA synovial tissues.

36 of mouse and human synovial fibroblasts and synovial tissues.

37 th osteoarthritis and arthritis-free control synovial tissues.

38 is in whom the synovial fluid (1 patient) or synovial tissue (1 patient) was positive for Tropheryma

39 RT-PCR) was used to identify mRNA for ODF in synovial tissues, adherent synovial fibroblasts, and act

40 the medial femoral condyle cartilage and the synovial tissue adjacent to the central portion of the m

41 nical trials, may lead to the development of synovial tissue analysis as a potential clinical tool fo

42 Synovial tissue analysis confirmed mononuclear leukocyte

43 Synovial tissue analysis has been instrumental in enhanc

44 to investigate the distribution of MTG in RA synovial tissue and also non-RA arthritis and healthy co

45 the activation of infiltrating leukocytes in synovial tissue and are a potential therapeutic target.

46 uman retrovirus-5 proviral DNA is present in synovial tissue and blood specimens from patients with r

47 en are produced by rheumatoid arthritis (RA) synovial tissue and can potentially induce mutations in

48 Pathways Analysis and compared to published synovial tissue and cartilage messenger RNA profiles.

49 d CCR5-immunoreactive cells were found in RA synovial tissue and colocalized with CD68+ macrophages.

50 a, is elevated in human rheumatoid arthritis synovial tissue and correlates with inflammatory cell in

51 Synovial tissue and fibroblast-like synoviocytes from RA

52 By forming a complex with p38 in synovial tissue and FLS, these kinases can potentially b

53 in whose expression is increased in inflamed synovial tissue and fluid in human rheumatoid arthritis

54 in inflammation by recruiting leukocytes to synovial tissue and fluid-and subsequently contributing

55 TSG-6 binds to hyaluronan in inflamed synovial tissue and forms a complex with a serine protea

56 We have now extended these findings to synovial tissue and further explored the mechanism under

57 sed at elevated levels in normal, OA, and RA synovial tissue and in primary RA synoviocytes.

58 cyclooxygenase (COX-2) are found both in the synovial tissue and in the cartilage.

59 Freshly isolated rheumatoid synovial tissue and isolated RA synovial fibroblasts inv

60 ther, these studies implicate cadherin-11 in synovial tissue and lining layer formation and provide a

61 or necrosis factor alpha and IL-1beta in the synovial tissue and lower protein levels of IL-1alpha an

62 e induction of apoptosis of cells within the synovial tissue and lymph nodes of lpr-APC-AdFasL-treate

63 was examined by PCR on genomic DNA of paired synovial tissue and peripheral blood cells of RA patient

64 d in vitro functional assays with rheumatoid synovial tissue and primary cells.

65 NR4A messenger RNA levels in synovial tissue and primary synoviocytes were measured b

66 so analyzed the expression of neuropilins in synovial tissue and SF, as they may interact with vascul

67 RA synovial tissue and synovial fluid macrophages expressed

68 T cell cytokine IL-17 is expressed in the RA synovial tissue and synovial fluid.

69 en demonstrated in rheumatoid arthritis (RA) synovial tissue and synoviocytes, no information is avai

70 tory leukocytes in rheumatoid arthritis (RA) synovial tissue and to the growth and proliferation of R

71 Synovial tissue and whole blood from 75 patients with rh

72 t-like synoviocytes (FLS) were isolated from synovial tissues and incubated with the NO donor S-nitro

73 d severity, enhanced osteoclast abundance in synovial tissues and osteoclastogenic propensities of bo

74 A synovial fibroblasts were isolated from RA synovial tissues and used between passages 3 and 9.

75 macrophage-derived chemokine (CCL22) in the synovial tissue, and also had reduced acute and late-sta

76 ed fibrinogen (CF) is abundant in rheumatoid synovial tissue, and anti-citrullinated protein Ab-posit

77 Vascularization was determined in the synovial tissue, and correlations with inflammation were

78 Apo A-I product was generated by RT-PCR from synovial tissue, and further, by the demonstration that

79 th inflammation in rheumatoid arthritis (RA) synovial tissue, and PAD2 and citrullinated proteins are

80 ynovium of RA patients compared with control synovial tissue, and that it is predominately expressed

81 th a stromal cell line (SCL) derived from RA synovial tissue, and the effects on apoptosis and expres

82 ions identified in rheumatoid arthritis (RA) synovial tissue are dominant negative.

83 Specific pathways within synovial tissues are emerging as associated with diverse

84 cell-membrane factors produced by rheumatoid synovial tissues are likely to play a role in the initia

85 The expression of Bim was reduced in RA synovial tissue as compared with controls, particularly

86 nic inflammatory synovial lesions and normal synovial tissue as well as from fetal lung and adult ski

87 was significantly low in RA serum, SFs, and synovial tissues, as well as in the serum and joints of

88 ontrast enhancement was measured in inflamed synovial tissue at half dose (0.05 mmol per kilogram of

89 In a series of 64 synovial tissue biopsies, lymphoid follicles with germin

90 ere found in a high proportion of RA patient synovial tissues but also in non-RA arthritis control ti

91 receptor expression were investigated in RA synovial tissue by immunohistochemistry and 2-color immu

92 and NOD2 expressions were determined in mice synovial tissue by RT-PCR.

93 suggest that p53 mutations are induced in RA synovial tissues by inflammatory oxidative stress.

94 of CXC chemokine receptor (CXCR)4 expressing synovial tissue CD4(+) memory T cells was significantly

95 levels of CD130 messenger RNA and protein in synovial tissue CD4+ T cells suggested that CD130 is up-

96 In the synovial tissue, CD8+ T cells were the major source of I

97 Synovial tissue cells participate in lymphocyte recruitm

98 duction of neutrophil-active chemokines from synovial tissue cells.

99 t of arthritis, and their migration into the synovial tissue coincides with the onset of clinical dis

100 fe and well tolerated procedure that enables synovial tissue collection from most joints/patients wil

101 Analysis of human RA synovial tissue confirmed that PBEF immunolocalized in a

102 ory sites, such as rheumatoid arthritis (RA) synovial tissue, contain large numbers of activated B ce

103 y expressed in RA B cells from patients with synovial tissue containing ectopic germinal centres comp

104 P3K gene expression in RA and osteoarthritis synovial tissue demonstrated mitogen-activated protein k

105 y analysis and real-time RT-PCR of the ankle synovial tissue demonstrated that hTNF/SphK1(-/-) mice h

106 This was due to lytic viral infection of synovial tissues demonstrated by PCR, immunohistochemist

107 imulated production of NH2-terminal PTHrP by synovial tissue directly invading cartilage and bone in

108 ferred human T cells in rheumatoid arthritis synovial tissue engrafted into immune deficient SCID mic

109 y shown that revascularization of minced JRA synovial tissues engrafted into SCID mice correlated wit

110 ated CD8(+)CD28(-)CD56(+) T cell clones from synovial tissues, expanded them in vitro, and adoptively

111 Synovial tissue explants were stimulated with VEGF, and

112 Giant cells that form within OA synovial tissue express high levels of cathepsin K mRNA.

113 indings in RA PB, CD4+ T cells in the SF and synovial tissue expressed low levels of CD126.

114 Osteoarthritis synovial tissues expressed much less wnt5a and fz5.

115 Synovial tissue expression of alphav integrins was deter

116 Synovial tissue expression of the chemokines interleukin

117 lood in vitro-differentiated macrophages, RA synovial tissue fibroblasts, and human microvascular end

118 tissue, including rheumatoid arthritis (RA) synovial tissue fibroblasts.

119 In the context of inflamed synovial tissues, FLS may be an important and hitherto o

120 isfatin/PBEF in the molecular patterns of RA synovial tissue, focusing on RA synovial fibroblasts (RA

121 DNA damage in inflamed synovium, we analyzed synovial tissues for microsatellite instability (MSI).

122 correlated with numbers of free microscopic synovial tissue fragments (r = 0.826, P < 0.0001).

123 nic factors in fresh JRA synovium and in JRA synovial tissue fragments that had been minced and then

124 Synovial tissue from 12 patients with active systemic JI

125 63 patients with Lyme arthritis (LA) and in synovial tissue from 9 patients.

126 epsin B, and interleukin-1beta (IL-1beta) in synovial tissue from control and affected joints were de

127 gulated in RA synovium compared with control synovial tissue from patients with osteoarthritis or ser

128 TNFalpha production in synovial tissue from patients with RA but not osteoarthr

129 the expression of selected gene products in synovial tissue from patients with RA compared with pati

130 icrovascular endothelium and is expressed in synovial tissue from patients with rheumatoid arthritis

131 Immunohistochemical analysis of synovial tissue from RA and OA patients revealed increas

132 dependent kinase inhibitor p21 is reduced in synovial tissue from RA patients compared to osteoarthri

133 but not SPHK-2) mRNA levels were observed in synovial tissue from RA patients.

134 lated in the sublining area of proliferating synovial tissue from RA patients.

135 in human and rabbit synovial fibroblasts and synovial tissue from rheumatoid arthritis (RA) patients.

136 Synovial tissues from 5 patients with rheumatoid arthrit

137 Synovial tissues from animals treated with targeted fuma

138 s the expression of CD40-downstream genes in synovial tissues from anti-citrullinated protein Ab-posi

139 ll genes were also significantly enriched in synovial tissues from arthralgia patients.

140 Synovial tissues from DA rats and DA.ACI(Cia25) rats obt

141 with real-time polymerase chain reaction on synovial tissues from day-32 ankles.

142 reactivity was assessed by immunostaining of synovial tissues from normal controls and from patients

143 ODF mRNA was detected by RT-PCR in whole synovial tissues from patients with RA but not in normal

144 and by activated T lymphocytes derived from synovial tissues from patients with RA.

145 erred them into NOD-SCID mice engrafted with synovial tissues from patients with rheumatoid arthritis

146 by immunohistochemistry using antibodies in synovial tissues from patients with rheumatoid arthritis

147 oducing predominantly GM-CSF are expanded in synovial tissues from patients with spondyloarthritis.

148 Synovial tissues from RA and osteoarthritis patients wer

149 ultured T cells with FLS lines isolated from synovial tissues from RA patients.

150 Through evaluation of synovial tissues from rheumatoid arthritis (RA) patients

151 naive B cells were significantly enriched in synovial tissues from UA, early RA, and established RA p

152 MD-1068, was added to primary cultures of RA synovial tissue, from which spontaneous cytokine release

153 ed with increased numbers of plasma cells in synovial tissue, greater numbers and activation of endot

154 Immunodepletion of fkn from five RA synovial tissue homogenates inhibited their ability to i

155 al cells and angiogenic activity found in RA synovial tissue homogenates.

156 ty in the rat cornea in vivo than did normal synovial tissue homogenates.

157 ed more IL-8 and ENA-78 compared with normal synovial tissue homogenates.

158 ment of bare area regions with fibrovascular synovial tissue in joints without inflammatory changes.

159 moglobin content reflecting the hyperemia in synovial tissue in metacarpophalangeal (MCP) joints of 1

160 ally beneficial in facilitating apoptosis of synovial tissue in patients with RA.

161 Synovial tissue in rheumatoid arthritis is characterized

162 ated mast cell degranulation in vitro and in synovial tissue in vivo.

163 ESE-1 is expressed in synovial tissues in RA and, to a variable extent, in OA,

164 ed the overexpression of wnt5a and fz5 in RA synovial tissues, in comparison to a panel of normal adu

165 Synovial tissue infections caused by L. pneumophila are

166 haracterize a newly identified population of synovial tissue-infiltrating natural killer (NK) cells o

167 Synovial tissue-infiltrating NK cells were evaluated for

168 similarly reduced, with less infiltration of synovial tissue into the underlying bone.

169 Immune-competent cell trafficking to synovial tissue is integral to the pathogenesis of RA.

170 by macrophages in rheumatoid arthritis (RA) synovial tissue is largely driven by contact-dependent a

171 e mechanism of this activation in rheumatoid synovial tissue is unknown.

172 that is characterized by hypertrophy of the synovial tissue, leukocyte infiltration, angiogenesis, a

173 IL-7 and IL-7R were coexpressed on RA synovial tissue lining and sublining macrophages and end

174 A significant decrease in synovial tissue lubricin gene expression was associated

175 in synovial fluid (SF) lavage specimens and synovial tissue lubricin gene expression were evaluated

176 Actin-normalized Western blot analysis of synovial tissue lysates confirmed the increased expressi

177 The reduction of synovial tissue macrophages is a reliable biomarker for

178 The inflamed microenvironment in the synovial tissue maintains responsiveness to IL-6 trans-s

179 es and growth factors elaborated by inflamed synovial tissues may contribute to osteoclast differenti

180 Thus, local production of EBV Ags in synovial tissues may not be the cause of the accumulatio

181 nd full-dose gadobenate dimeglumine-enhanced synovial tissue (mean: 914.35 +/- 251.1 vs 1022 +/- 244.

182 liferation, consistent with the hyperplastic synovial tissue observed in MPS patients.

183 n of Legionella pneumophila serogroup 4 from synovial tissue obtained from an 80-year-old female with

184 FLS were isolated from synovial tissue obtained from both diseased and nondisea

185 of the CD45+ mononuclear cell infiltrate in synovial tissue obtained from patients undergoing primar

186 Moreover, macrophages in synovial tissue obtained from patients with rheumatoid a

187 significantly increased arthritis severity, synovial tissue OC abundance, and bone erosion.

188 beta and TNFalpha mRNA, respectively, in the synovial tissue of DA.ACI(Cia10) congenic rats compared

189 we identified GAG-binding cells in inflamed synovial tissue of human patients with RA.

190 is revealed that the intimal lining cells of synovial tissue of inflamed joints of patients with rheu

191 tion, we have detected bacterial rRNA in the synovial tissue of late-stage RA and non-RA arthritis co

192 ipheral blood (PB), synovial fluid (SF), and synovial tissue of patients with RA as well as in the PB

193 t sites of chronic inflammation, such as the synovial tissue of patients with RA.

194 B19 DNA has been detected in studies in the synovial tissue of patients with rheumatoid arthritis, b

195 FLS were isolated from synovial tissue of RA patients and from DA rats and arth

196 CD4+CD28- T cells in peripheral blood and synovial tissue of RA patients were found to express NKG

197 ipheral blood (PB), synovial fluid (SF), and synovial tissue of RA patients.

198 of CMV and EBV was detectable by PCR in the synovial tissue of RA.

199 e in the synovial fluid of 1 patient and the synovial tissue of the other.

200 the liver and was found to be upregulated in synovial tissues of CIA mice.

201 Synovial tissues of inflamed joints contain cells expres

202 FLS obtained from the synovial tissues of patients with RA or osteoarthritis w

203 tudying the B lymphocytes that expand in the synovial tissues of patients with rheumatoid arthritis (

204 h mast cells (MCs) often are abundant in the synovial tissues of patients with rheumatoid arthritis,

205 ced ectopic GC formation, as observed in the synovial tissues of patients with rheumatoid arthritis.

206 been measured in plasma, synovial fluid, and synovial tissues of patients.

207 ri to infect multiple tissues, including the synovial tissues of the joints.

208 s, we have investigated the expression in RA synovial tissues of various embryonic growth factors fro

209 Lubricin mRNA expression levels in synovial tissue on days 4 and 7 after arthritis inductio

210 ies have not been identified previously from synovial tissue or fluid from arthritis patients.

211 gen (HLA)-DR molecules in patients' inflamed synovial tissue or joint fluid and tested each epitope f

212 MTG were not found in healthy synovial tissue or the tissue of patients with undiffere

213 ere no differences in EBV gene expression in synovial tissues or peripheral blood when comparing RA w

214 (JRA) is a tumor-like expansion of inflamed synovial tissue, or pannus, which causes much of the joi

215 in-11 in the specific adhesion of FLS and in synovial tissue organization and behavior in health and

216 t component of the rheumatoid arthritis (RA) synovial tissue pannus.

217 expressed in RA compared with osteoarthritis synovial tissues, particularly in the CD68-negative, fib

218 thritis (RA) focusing on the contribution of synovial tissue pathology (synovitis) in determining div

219 Conditioned media from explant cultures of synovial tissue, periprosthetic soft tissue (interface m

220 se results indicate that SCL derived from RA synovial tissue play a role in promoting B cell survival

221 that these rearrangements could occur in the synovial tissues, presumably in pseudo-germinal centers,

222 Moreover, homogenates from RA synovial tissue produced significantly more chemotactic

223 c assessment, micro-computed tomography, and synovial tissue quantitative polymerase chain reaction a

224 RA synovial tissue RANTES (regulated upon activation, norma

225 vivo, we selected a model using whole human synovial tissue rather than isolated cells.

226 CRT citrullination in synovial tissue samples and cell cultures was determined

227 Synovial tissue samples from 32 (31%) of 104 patients wi

228 ls of active versus persistent infection and synovial tissue samples from patients with chronic Chlam

229 Peripheral blood, synovial fluid, and synovial tissue samples were obtained from patients with

230 Synovial tissue samples, obtained prior to fracture and

231 by 2-color immunohistochemistry analysis of synovial tissue samples.

232 for Vbeta20 clonotypes, a motif was found in synovial tissue samples.

233 We utilized the RA synovial tissue SCID mouse chimera system to examine hum

234 Using microdissected RA synovial tissue sections, we observed abundant p53 trans

235 ed proliferation of RASFs and hyperplasia of synovial tissue seen in RA synovium.

236 thritis (RA), and macrophages are reduced in synovial tissue shortly after initiation of TNF inhibito

237 Immunohistological sections of RA synovial tissue showed strong staining for B7-H3 on FLS.

238 both normal muscle biopsy specimens and JRA synovial tissue specimens.

239 was undertaken to examine its expression in synovial tissue (ST) and role in arthritis.

240 DNA was prepared from synovial tissue (ST) and several synovial fluid (SF) sam

241 n-1 (THBS1, alias TSP-1) expression in human synovial tissue (ST) during the resolution phase of chro

242 ction of key proinflammatory mediators in RA synovial tissue (ST) explants.

243 t, by proinflammatory factors produced by RA synovial tissue (ST) fibroblasts and macrophages, result

244 cular endothelial growth factor (VEGF) in RA synovial tissue (ST) fibroblasts, and the underlying sig

245 53 tumor suppressor gene is overexpressed in synovial tissue (ST) from patients with longstanding rhe

246 In rat AIA, synovial tissue (ST) macrophages, fibroblasts, endotheli

247 In a chimeric SCID mouse/human synovial tissue (ST) model, mice were engrafted subcutan

248 canases (aggrecanase-1 and aggrecanase-2) in synovial tissue (ST) or fibroblast-like synoviocytes (FL

249 Synovial tissue (ST) samples from 167 patients with oste

250 ined in 65 synovial fluid (SF) samples and 7 synovial tissue (ST) samples from 17 patients with antib

251 cytes, including monocyte/ macrophages, into synovial tissue (ST), but factors mediating the ingress

252 s overexpressed in rheumatoid arthritis (RA) synovial tissue (ST), few synoviocytes undergo apoptosis

253 mmation, including rheumatoid arthritis (RA) synovial tissue (ST), often contain high endothelial ven

254 mokine receptors on CD3+ T lymphocytes in RA synovial tissue (ST), RA SF, RA PB, and NL PB.

255 ound mononuclear cell (MNC) recruitment into synovial tissue (ST), thought to be due in part to tumor

256 We used an RA synovial tissue (ST)-SCID mouse chimera model to evaluat

257 kocytes leave the bloodstream and invade the synovial tissue (ST).

258 tion into inflamed rheumatoid arthritis (RA) synovial tissue (ST).

259 gulating CTGF gene and protein expression in synovial tissue, suggesting a link with the disease cour

260 chain involved in antigen recognition in the synovial tissue, synovial fluid, and peripheral blood fr

261 was used to isolate CD4 T cells residing in synovial tissue T cell/B cell follicles.

262 Synovial tissue T cells and B cells cooperate in differe

263 Consistent with this phenotype, synovial tissue T cells responded to trans-signaling by

264 HLA-DRB1-matched synovial tissues that were infiltrated by T cells, macro

265 as TSG-6 was broadly detectable in arthritic synovial tissue, the highest level of TSG-6 was co-local

266 zation of pro-myelomonocytic U937 cells into synovial tissue transplanted into SCID mice.

267 ion in the markers of bone turnover (OC) and synovial tissue turnover (HA and PIIINP) support the gen

268 In rat AIA, IL-4 reduces synovial tissue vascularization via angiostatic effects,

269 e production and degranulation by stimulated synovial tissue versus normal blood NK cells were evalua

270 IL-4 induced a reduction in synovial tissue vessel density, which was paralleled by

271 Synovial tissue was analyzed by immunohistochemistry for

272 unosorbent assay, and expression of TSG-6 in synovial tissue was assessed by immunohistochemistry.

273 y and K/BxN serum transfer-induced arthritic synovial tissue was defined using immunohistochemical st

274 xpression of IL-7 and IL-7R in RA and normal synovial tissue was demonstrated by immunohistochemistry

275 Follicular response in the spleen and in synovial tissue was determined by in situ immunohistolog

276 Cadherin 11 expression in rheumatoid synovial tissue was evaluated using immunohistochemistry

277 RA synovial tissue was examined by immunohistochemistry.

278 D130 was minimal in the SF, its level in the synovial tissue was high.

279 ollicular response both in the spleen and in synovial tissue was inhibited by anti-CXCL13 treatment.

280 DA.ACI(Cia10) congenic rat synovial tissue was more likely to preserve its normal h

281 RA synovial tissue was obtained from RA patients during joi

282 Microarray analysis of synovial tissue was performed and gene expression patter

283 Microarray analysis of synovial tissue was performed, and gene expression patte

284 ent of neutrophils into infected kidneys and synovial tissue was significantly higher in mice inocula

285 reased T cell and macrophage infiltration in synovial tissues was accompanied by reduced P-selectin e

286 vealed that peak C was virtually absent from synovial tissue, was present as a minor component in ski

287 Joints and synovial tissue were collected 32 days after the inducti

288 s, and at synovectomy, all results of PCR of synovial tissue were negative.

289 ured fibroblast-like synoviocytes (FLS), and synovial tissues were examined by immunohistology with a

290 ive, mononucleated or multinucleated, within synovial tissue) were also positive for a macrophage-spe

291 pidly cytokine inducible, up-regulated in RA synovial tissue, where it is cell-bound, and up-regulate

292 erforin-positive T cells were present in the synovial tissue, where their frequency correlated with t

293 the migration of monocytes from blood to RA synovial tissue, where they differentiate into macrophag

294 CTMC) phenotype in both normal and arthritic synovial tissue, which expresses mMCP-4, -5, -6, and -7,

295 d in activated T lymphocytes derived from RA synovial tissue, which were expanded by exposure to anti

296 Synovial tissues with diffuse inflammatory infiltrates h

297 infiltrates had high levels of TSP2, whereas synovial tissues with ectopic germinal center reactions

298 Five synovial tissues with severe to mild lymphocytic infiltr

299 Migration of these cells to synovial tissue would result in the transgene being swit

300 paucity of apoptosis has been observed in RA synovial tissues, yet the mechanism remains unknown.