ライフサイエンスコーパス: syntenic

1 ea that the majority of Drosophila genes are syntenic.

2 in animal models where a single copy of the syntenic 16p11.2 region has been deleted have revealed m

3 ral cortex from mouse models with CNV of the syntenic 7qF3 region and lymphoblast lines from 34 membe

4 region around the origin of replication was syntenic across the genus.

5 a combination of phylogenetic analyses with syntenic alignment of mammalian CD59 genes to identify t

6 At the genome level, syntenic alignments between sorghum (Sorghum bicolor) an

7 al spans in their genomic context, including syntenic alignments with other kinetoplastid organisms.

8 e proteins, as a model for gene evolution by syntenic alignments with sorghum and rice, two genomes t

9 haplotype" (or "haploid genotype") refers to syntenic alleles inherited on a single chromosome, and w

10 Genetic, evolutionary and syntenic analyses indicate that chIFN-kappa is a type I

11 bination of phylogenetic, splicing site, and syntenic analyses revealed that zebrafish have two per1

12 gh comprehensive sequence, phylogenetic, and syntenic analyses, we fully describe the identification

13 Genome syntenic analysis between spinach and sugar beet suggest

14 Syntenic analysis of regions harbouring GmSNAP genes in

15 'Syntenic anchors' are conserved non-repetitive locations

16 e orthologous relationships based on sharing syntenic anchors, collocating in the same syntenic block

17 The proportion of genes syntenic and collinear within each synteny block is rela

18 rived open reading frames (ORFs) that showed syntenic and copy number variation among species, but we

19 ferentiation complex (EDC) locus comprises a syntenic and linear cluster of genes whose concomitant e

20 n DNA replication and genome maintenance, is syntenic and linked to Trp53 in mice and humans.

21 species elements (LIMEs), which include both syntenic and nonsyntenic regions, of at least 100 identi

22 by phylogenetic gene family trees help infer syntenic and orthologous relationships.

23 Comprehensive syntenic and phylogenetic analyses support our hypothesi

24 P compiles gene and gene family information, syntenic and phylogenetic context and tissue-specific tr

25 In better studied species, ODG can perform syntenic annotation translations or rapidly identify cha

26 t in all five genomes, and display conserved syntenic architecture with respect to gene order, orient

27 ed-end sequences (2 x 76 bp) provides a good syntenic assembly with >95% high-quality coverage (more

28 To date, this syntenic association of the Fugu C4 and other MHC class

29 Of the 12 syntenic associations of human chromosomes present in th

30 QTL-peak candidate genes delineated are syntenic between rat and human genomes, increasing clini

31 located between the lplA and glnQ genes are syntenic between the two phytoplasmas and contain the ma

32 netic mapping revealed that 83% of ESTs were syntenic between wheat and rice, a far higher level of s

33 nic blocks across species, the disruption of syntenic blocks (via chromosomal inversion events) and i

34 or themes are addressed: the conservation of syntenic blocks across species, the disruption of synten

35 char also revealed extensive conservation of syntenic blocks across species, which was generally cons

36 Identification of conserved syntenic blocks across these genomes suggests a large nu

37 Comparison of syntenic blocks across this large genomic data set confi

38 nally, we identify and analyze the conserved syntenic blocks among reconstructed ancestral genomes an

39 y manifested as chromosomal rearrangement of syntenic blocks and DNA insertions/deletions.

40 ng syntenic anchors, collocating in the same syntenic blocks and sharing the same annotated protein f

41 other hand, an analysis of the disruption of syntenic blocks between species allowed the identificati

42 ey comparative alignment type and search for syntenic blocks between two sequences and zoom in to vie

43 C6 were the result of complex reshuffling of syntenic blocks from three (AK3, AK5 and AK11), three (A

44 Among the >300 syntenic blocks identified are segments of over 40 Mb wi

45 The largest syntenic blocks occur in regions with low meiotic recomb

46 chicken, turkey and zebra finch, identifying syntenic blocks of at least 250 kb.

47 e rate in another, when comparing homologous syntenic blocks of the genome.

48 he location and orientation of 53 C. hystrix syntenic blocks on the seven cucumber chromosomes, and a

49 Comparisons of syntenic blocks reveal clear structural similarities in

50 vely reshuffled, leading to a minimum of 921 syntenic blocks shared between the species.

51 ECRbase features a database of syntenic blocks that recapitulate the evolution of rearr

52 Arabidopsis' unique gene content is found in syntenic blocks that were formed during the most recent

53 Micro-syntenic blocks were detected in apple (Malus x domestic

54 sed for a fine-scale comparison of conserved syntenic blocks with the human and canine genomes.

55 tly ordered anchors between the two genomes (syntenic blocks).

56 s repetitive sequences, telomeres, conserved syntenic blocks, and expansion of pathogenicity-related

57 er scaffolds on the basis of the analysis of syntenic blocks.

58 ethod, with 3,941 ORFs present in conserved, syntenic blocks.

59 ra genome at many junctions between adjacent syntenic blocks.

60 netic networks were found for individual rye syntenic blocks.

61 hat repeats and repeat-clusters are found at syntenic break points between E. histolytica and E. disp

62 e organized in clusters, frequently found at syntenic break points providing insights into their cont

63 pped the locations of 31 major human-chicken syntenic breakpoints.

64 ic genes, many of which are found at or near syntenic breaks, implicating evolutionary breakpoint reg

65 tegrative Web-based system to find and align syntenic chromosomal regions and visualize the output in

66 The gl8a and gl8b genes map to syntenic chromosomal regions, have similar, but not iden

67 s chromosomes in the two species from highly syntenic chromosomes in most cases to chromosomes with a

68 JY-1-like sequences are present on syntenic chromosomes of other vertebrate species, but la

69 , phylogenetic profiles (presence/absence of syntenic conservation across 17 species), and locations

70 cat, human, and mouse highlights regions of syntenic conservation and species-specific gene rearrang

71 everal previous studies examined genome-wide syntenic conservation to infer the contents of ancestral

72 genomes followed by post-processing of those syntenic datasets to identify and plot gene retention pa

73 e family expansion are often associated with syntenic discontinuities that-along with gene divergence

74 ther gene that resembles CRH in sequence and syntenic environment.

75 The results show that a syntenic expression site is present in all strains of A.

76 oximately 25 kb of all 4 linear plasmids was syntenic for orthologous genes for plasmid maintenance o

77 e timing of gene set duplications located on syntenic gamma blocks.

78 ete basal fungal lineage, the sex locus is a syntenic gene cluster governing sexual reproduction in w

79 We also discovered a syntenic gene cluster of transcription factors that regu

80 Strikingly dissimilar conserved syntenic gene content, gene sequence diversity signature

81 subfunctionalization and/or fractionation of syntenic gene sets, and conserved noncoding sequence con

82 erved housekeeping genes are concentrated in syntenic gene-rich blocks, whereas virulence genes are d

83 eudoobscura We find that while the original (syntenic) gene copy has generally retained the ancestral

84 including insertions of high numbers of non-syntenic genes and a high rate of tandem gene duplicatio

85 ic changes; it has acquired more than 80 non-syntenic genes and only 13 ancestral genes are shared am

86 The high frequency of non-syntenic genes and rapid local gene evolution correlate

87 s were highly conserved with less than 1% of syntenic genes being subject to differential fractionati

88 ed a more relaxed selection pressure for non-syntenic genes compared to syntenic genes, and gene onto

89 Local duplication of non-syntenic genes contributed significantly to the expansio

90 lative codon bias is broadly conserved among syntenic genes from different trypanosomatids.

91 to establish the chromosomal arrangement of syntenic genes from model grass species.

92 nd gene ontology analysis indicated that non-syntenic genes may be enriched in functions involved in

93 Insertions of non-syntenic genes occurred at a similar rate along the chro

94 These non-syntenic genes on 3B have high sequence similarity to at

95 icken leptin together with a cluster of five syntenic genes provided the final proof for its identifi

96 whereas, by applying the same criteria, non-syntenic genes represent on average only 10 % of the pre

97 The few variably fractionated syntenic genes that were identified are unlikely to cont

98 Between these two genomes, syntenic genes were highly conserved with less than 1% o

99 comparisons of 60 diverse inbred lines, non-syntenic genes were six times more likely to be variable

100 pressure for non-syntenic genes compared to syntenic genes, and gene ontology analysis indicated tha

101 These non-syntenic genes, including prolamin and resistance-like g

102 re six times more likely to be variable than syntenic genes, suggesting that comparisons among additi

103 are under different selection pressure than syntenic genes.

104 large-scale presence/absence variation among syntenic genes.

105 plication and are therefore younger than the syntenic genes.

106 e database since its last release, including syntenic genome regions for human poly(A) sites in seven

107 We further show that orthologs in syntenic genomic blocks are more likely to share correla

108 reakage and fusion events based on conserved syntenic genomic blocks lead to conserved patterns of ka

109 es resulted in identification of a conserved syntenic genomic island consisting of up to 33 core gene

110 first report of a diverse family of related syntenic genomic islands with a deep evolutionary origin

111 mals because no direct homologs exist at the syntenic genomic locus in metatherian (marsupial) or pro

112 mparison of assemblies to alignment of large syntenic genomic regions and whole genome human/mouse al

113 binds to a core group of approximately 1200 syntenic genomic regions in both species, with these con

114 both the gene structure and alignment of two syntenic genomic regions.

115 om mammals to fish, that are maintained in a syntenic group across vertebrates.

116 A WWRH map of the syntenic group composed of linkage groups 9 and 13 was c

117 h GC-content observed for the chicken leptin syntenic group suggests that other similar clusters of g

118 oups, LG 13 and LG 9, were combined into one syntenic group, and the chromosome 1 linkage group marke

119 In this syntenic group, the RNA-binding protein 28 (RBM28) was i

120 P, 52 of 102 SSR markers were mapped into 16 syntenic groups.

121 Furthermore, the repeated recruitment of syntenic homologs from large gene families strongly impl

122 biogenesis were identified, 14 of which were syntenic homologs in maize and S. viridis.

123 locus maps to a 3.9-Mb region, with complete syntenic homology to human chromosome 14, that contains

124 gene is located on chromosome 2, a region of syntenic homology with human chromosome 20, and in a reg

125 region on distal mouse chromosome 1 and its syntenic human counterpart 1q23-42 show strong evidence

126 ptibility locus Nba2 on chromosome 1 and the syntenic human locus are associated with a loss of immun

127 GEDDs along the mouse chromosomes that were syntenic in human.

128 ed the tree tests, the bulk (8 of 10) remain syntenic in the genomes with only a few (3 of the 10) ha

129 mparative genomics approaches are limited to syntenic inference and recombination is suppressed withi

130 As an example, we have used the syntenic information for the rat Rf-1 disease region and

131 Using the syntenic information in combination with expression data

132 sequence validated by genetic, physical and syntenic information.

133 Seventeen conserved syntenic linkage blocks making up the rye and barley gen

134 These profiles were cross-referenced with syntenic locations exhibiting hippocampal DNA methylatio

135 hologs of each PAI can be found in conserved syntenic locations in other Pseudomonas species, indicat

136 an and rat, with major clusters occurring in syntenic locations.

137 Similarly, the mouse clade B serpins map to syntenic loci at 13A3.2 and 1D, respectively.

138 melon and watermelon, we uncovered conserved syntenic loci encoding metabolic genes for distinct cucu

139 R) in approximately 3000 human and zebrafish syntenic loci, we detected approximately 300 pairs of di

140 indicates that these proteins are encoded by syntenic loci.

141 An identical domain was activated at the syntenic locus in a specific molecular subclass of spont

142 is insufficient to account for the extensive syntenic losses described in Lovell et al.

143 The rat-to-human syntenic map displays rearrangement of this region on ra

144 Using syntenic mapping and the functional characterization of

145 es or projected from a related species using syntenic mapping information.

146 Syntenic mapping is well-suited to annotate genomes clos

147 ment with homologs from related species, and syntenic mapping with other cereal species.

148 7 of cultivated and wild cucumbers, and the syntenic melon chromosome I suggested that the paracentr

149 series of rearrangements engineered over the syntenic mouse region, we show that this interval contai

150 human transcripts show no orthologues in the syntenic mouse regions although 13 have homologous seque

151 y, activity could not be demonstrated with a syntenic murine receptor homolog.

152 and Supt3h promoters, consistent with their syntenic nature.

153 us and duplicated regions to construct local syntenic networks, we show that a shared ancient hexaplo

154 ution in rat, mouse, and human identified 11 syntenic NR gene blocks, including three small clusters

155 aize and rice reveals that 13% of genes with syntenic orthologs in both species exhibit conserved imp

156 Nonsyntenic genes that lack syntenic orthologs in other grass species, and thus evol

157 elated expression patterns compared with non-syntenic orthologs.

158 Although they were syntenic, overlapping a- and b-type ribotype genomes har

159 known as homeologs, homoeologs, ohnologs, or syntenic paralogs, is uneven between duplicate regions.

160 These syntenic patches are often not colinear, however, and fo

161 d core proteome of about 6200 genes in large syntenic polycistronic gene clusters.

162 lting from differential fractionation in the syntenic portion of the genome using two whole-genome de

163 ns, insertions, or deletions) and located in syntenic positions in at least two genomes.

164 cription factors, maintain their chromosomal syntenic positions throughout angiosperm evolutionary ti

165 remnants of all seven dedicated GAL genes as syntenic pseudogenes, providing a rare glimpse of an ent

166 look at regions that are especially prone to syntenic rearrangements.

167 The analysis of the murine and human syntenic region and its control has important implicatio

168 apping in mice to association mapping of the syntenic region in the human genome.

169 The syntenic region in the mouse is organized and imprinted

170 Furthermore, this response is conserved at a syntenic region in zebrafish cells.

171 Several genes within a syntenic region of human and mouse chromosome 1 are asso

172 amplification at mouse chromosome 9qA1, the syntenic region of human chromosome 11q22.

173 amin K-dependent protein deficiencies to the syntenic region of human chromosome 16.

174 g the human orthologue highly conserved on a syntenic region of human chromosome 7p12.

175 7.6-kb GC-rich repeat units reside within a syntenic region of mouse chromosome 1.

176 in the region of human chromosome 21 and the syntenic region of mouse chromosome 16, trisomy of which

177 hin the human leukocyte receptor complex and syntenic region of mouse chromosome 7, named T cell-inte

178 for both nephropathy and albuminuria in the syntenic region of this interval for both human and mous

179 The human syntenic region of this locus has been previously linked

180 most complete deletion (CD) of the conserved syntenic region on chromosome 5G2.

181 CRISPR/Cas9 technique to delete in mice the syntenic region on chromosome 8 to create a Dnajb1-Prkac

182 us autoimmune diseases have been mapped to a syntenic region on human chromosome 2q33.

183 ice and conducted association mapping of the syntenic region on human chromosome Xp22.

184 rbor a duplication spanning the entire Hsa21 syntenic region on Mmu10, Mmu16, or Mmu17, respectively.

185 [Df(11)17] or duplication [Dp(11)17] of the syntenic region on mouse chromosome 11 that spans the ge

186 duplication [Dp(11)17 ] (Dup mutant) of the syntenic region on mouse chromosome 11.

187 tion spanning the entire human chromosome 21 syntenic region on mouse chromosome 16 in mice using Cre

188 proximately 56.5% of the human chromosome 21 syntenic region on mouse chromosome 16.

189 maize chromosome 3, could be aligned with a syntenic region on rice (Oryza sativa) chromosome 1, whi

190 B strain, germline-encoded regulation of the syntenic region resulted in decreased miR-15a/16-1.

191 Map3k1 within the syntenic region was expressed in the embryonic mouse gon

192 n the mouse, as has been shown for the human syntenic region.

193 le genome fractionation requires identifying syntenic regions across genomes followed by post-process

194 atterns, whose parental genes are located in syntenic regions and/or have clear orthologs in at least

195 mapped a subset of OC mouse ESTs to several syntenic regions associated with human autosomal and rec

196 regions and genes within a single genome or syntenic regions between related genomes.

197 e duplicates as well as the absence of large syntenic regions consisting of duplicated gene copies im

198 ne disease models, and to disease-regulating syntenic regions identified in autoimmune patients on hu

199 In a wider context, the syntenic regions identified in peach, apple and strawber

200 ed an automated system to identify conserved syntenic regions in a primary genome using as outgroup a

201 Finally, analysis of corresponding syntenic regions in the mouse, rat and chimp genomes ind

202 cluster of CslF genes that remain located in syntenic regions of all the grass genomes examined.

203 Single coorthologs of Baf1 are found in syntenic regions of brachypodium (Brachypodium distachyo

204 ies, genome-wide search for oncogenes within syntenic regions of chromosome gain.

205 Analyses of relaxin family genes on syntenic regions of model tetrapods showed that the A ch

206 econd, when mapping the identified CNAs onto syntenic regions of the human genome, we noted that the

207 H3K4me1, and H3K27Ac levels were detected at syntenic regions of the IL-10 locus in mouse neutrophils

208 rries duplications spanning the entire Hsa21 syntenic regions on all three mouse chromosomes.

209 tered tandemly, but instead are dispersed in syntenic regions on different chromosomes, most likely a

210 th DS, particularly the impacts of different syntenic regions on these phenotypes.

211 evolutionarily conserved positions, occur in syntenic regions, and evolve under purifying selection.

212 tein sequences, gene models and annotations, syntenic regions, protein families and phylogenetic tree

213 tive loci fall outside the inferred colinear/syntenic regions, suggesting that many small rearrangeme

214 or exhibit no p63 binding in the orthologous syntenic regions, typifying an occupancy lost subset.

215 ition and loss, and rearrangement within the syntenic regions-have shaped the genomes of each parasit

216 as BAC fingerprint, other genomic maps, and syntenic relations with other genomes.

217 We accomplished this using syntenic relationship among four closely related species

218 ve analyses were undertaken to determine the syntenic relationship between L. perenne/F. pratensis an

219 There is a strong syntenic relationship between the two zebrafish genes an

220 Defining syntenic relationships among orthologous gene clusters i

221 the diploid sorghum genome identified clear syntenic relationships and collinear tracts.

222 genomic analysis identifies chromosome-level syntenic relationships between bottle gourd and other cu

223 Sequence and syntenic relationships between zebrafish and human genes

224 s chromosomal rearrangements that break down syntenic relationships occur; however, they do not appea

225 The syntenic relationships of similar genes in other teleost

226 it also facilitates the characterization of syntenic relationships with other cultivated and model l

227 The syntenic relationships with other grass genomes examined

228 h to organize and interpret massive pairwise syntenic relationships.

229 leta and L. gigantea, and investigated local syntenic relationships.

230 by long-range chromatic interactions through syntenic repeats combined with regional methylation spre

231 1BS aneuploidy are related to rice genes on syntenic rice chromosome 5 short arm (5S).

232 man chromosome 17q differs from CFA9 and the syntenic rodent chromosomes through two macroreversals o

233 To attain functional information about this syntenic segment in mice, we have generated a 6.9-Mb del

234 mouse mutant with a targeted deletion of the syntenic segment of the mouse X chromosome that phenocop

235 selection signature that spanned a conserved syntenic segment to bovine chromosome 12 on caprine and

236 ns by finding the best alignment between two syntenic sequences, while at the same time finding biolo

237 Chains (putative syntenic sets of anchors) are computed using a dynamic p

238 ls containing a heterozygous deletion of the syntenic SMS critical region, were observed in Rai1(+/-)

239 ions are processed pseudogenes; we define a "syntenic" subset of the alignments that excludes these a

240 titive elements, segmental duplications, and syntenic tandem DNA repeats were enriched in methylation

241 The S. aureus and S. epidermidis genomes are syntenic throughout their lengths and share a core set o

242 small 350-kb amplicon from a region that is syntenic to a much larger locus amplified in human cance

243 This locus is syntenic to a region of human chromosome 4q13.3 containi

244 g proteins of the C4 cycle in S. viridis are syntenic to homologs used by maize.

245 ptn to chromosome 2, within a region that is syntenic to human 10p14.

246 f mouse chromosome 11B3, a 4-megabase region syntenic to human 17p13.1, produces a greater effect on

247 6v1b1 maps to a region of mouse chromosome 6 syntenic to human 2p13, the location of ATP6V1B1.

248 he distal end of rat chromosome 14, a region syntenic to human 2p13-p16 and proximal mouse 11.

249 This DNA region, syntenic to human 2q31-32, contains a range of regulator

250 ized on chromosome 19 at bands C2-C3 that is syntenic to human chromosome 10q24-26; (iii) N-CDase exp

251 row interval on bovine chromosome 15 that is syntenic to human chromosome 11p12-p11.2.

252 n mice that harbor a chromosomal duplication syntenic to human chromosome 21q.

253 Interestingly, HIVAN1 is syntenic to human chromosome 3q25-27, an interval showin

254 pe and markers located on CFA34, in a region syntenic to human chromosome 3q26.

255 hymic lymphomas with t(12;14) translocation, syntenic to inv(14;14) in humans.

256 m of rice chromosome 3, which is known to be syntenic to long arms of group-4 chromosomes of wheat.

257 We also noted that PUL1,6-beta-glucan is syntenic to many PULs from other Bacteroidetes, suggesti

258 of allelic loss of chromosome 16q, which is syntenic to mouse chromosome 8.

259 e of linkage to BMD phenotypes in the region syntenic to our linkage finding on chromosome 1q.

260 ity to each other in aligned regions and are syntenic to phage BcepNazgul.

261 These loci are syntenic to regions on human chromosomes 17q and 5q impl

262 CD8+ T cells, and genetic linkage to disease syntenic to that found in humans.

263 ately one-half of it in a chromosomal region syntenic to that of the mouse, with similar intron-exon

264 ops3) maps to the mouse chromosome 11 region syntenic to the common deletion interval for the Smith-M

265 a chromosomal deficiency spanning a segment syntenic to the human 22q11.2 locus.

266 lyrata p4-siRNA hot spots are generally not syntenic to the most active p4-siRNA hot spots of A. tha

267 /lpr mice, with trans-repression of a region syntenic to the murine CD8b promoter.

268 ith a duplication of a 2-Mb genomic interval syntenic to the PTLS region and identified consistent be

269 a heterozygous deletion in the mouse region syntenic to the SMS common deletion, and exhibit craniof

270 a 12.67-Mb interval (8q21.13-q22.1) that is syntenic to the Wpk locus in rat, which is a model with

271 amplifications and deletions targeting loci syntenic to those not only in human T-ALL but also in di

272 quired copy number gains and losses that are syntenic to those observed in human MYCN-amplified NBL i

273 c regions on human chromosome 21 (Hsa21) are syntenic to three regions in the mouse genome, located o

274 nimal genomes, we found the previously known syntenic UCEs as well as previously undescribed nonsynte

275 a region of canine chromosome CFA15 that is syntenic with a region of human chromosome 14 (HSA14q11.

276 This amplicon is syntenic with a similar chromosome 11q22 amplicon identi

277 acteria such as transposases and integrases) syntenic with ARGs were rare in soil by comparison with

278 A. carolinensis microchromosomes are highly syntenic with chicken microchromosomes, yet do not exhib

279 porting the conclusion that the two loci are syntenic with conservation of function.

280 The M. truncatula region is syntenic with duplicated regions of Arabidopsis chromoso

281 s to canine chromosome 9 (CFA9), in a region syntenic with gene-dense human chromosome 17q.

282 1 amplifications and chromosome 4 deletions, syntenic with human 17q21-25 and 1p35-36, respectively.

283 to a 0.44 Mb interval of mouse chromosome 1 syntenic with human 1q23.2.

284 d of mouse chromosome 17 in a region that is syntenic with human chromosome 21q22.3, where the gene f

285 e trac mutation maps to mouse chromosome 17, syntenic with human chromosome 2p21-22.

286 This region is syntenic with human chromosome 9 where the gene encoding

287 This mouse QTL is syntenic with human chromosome 9p.

288 tion in the H. rubra mitochondrial genome is syntenic with most malacostracans that have been examine

289 nsposable elements and are less likely to be syntenic with orthologous genes in other grasses.

290 several growth factor proteins, and regions syntenic with pearl millet or maize genomic regions that

291 This region is syntenic with previously identified blood pressure-relat

292 ost interestingly, AID induces DSBs at sites syntenic with sites of translocations, deletions, and am

293 al of 64% and 66% of Ae. tauschii genes were syntenic with sorghum and rice genes, respectively.

294 The chl gene is on a region of chromosome 21 syntenic with the area of murine chromosome 7 bearing th

295 ied a locus on chromosome 14 (34.5-41.4 Mb), syntenic with the human 10q22-q23 schizophrenia-suscepti

296 at the IFITM locus exists in chickens and is syntenic with the IFITM locus in mammals.

297 that 27 % of the 3B predicted genes are non-syntenic with the orthologous chromosomes of Brachypodiu

298 This gene order is syntenic with the vernalization1 locus responsible for f

299 the L.monocytogenes genomes are essentially syntenic, with the majority of genomic differences consi

300 hat shares high sequence similarity to a non-syntenic zebrafish analog, cat7l Defects caused by inter