ライフサイエンスコーパス: synthesis inhibition

1 smaller effect on nrd expression during DNA synthesis inhibition.

2 ry were similar to those produced by protein synthesis inhibition.

3 partial agonist activity as measured by DNA synthesis inhibition.

4 hormones, developmental signals, and protein synthesis inhibition.

5 observed appeared to be a consequence of DNA synthesis inhibition.

6 and hypertension in response to nitric oxide synthesis inhibition.

7 nvolved recovery from stress-induced protein synthesis inhibition.

8 uggest the presence of ER stress and protein synthesis inhibition.

9 cludes eIF2alpha phosphorylation and protein synthesis inhibition.

10 it down recapitulates the effects of protein synthesis inhibition.

11 nous mRNAs, leading to a strong host protein synthesis inhibition.

12 cell monolayers from ricin-mediated protein synthesis inhibition.

13 synthesis without an effect on host protein synthesis inhibition.

14 e from mechanisms unrelated to prostaglandin synthesis inhibition.

15 M breakdown, were ruled out as causes of RNA synthesis inhibition.

16 gardless of MHV-induced general host protein synthesis inhibition.

17 -6, during virus-induced severe host protein synthesis inhibition.

18 ring sustained hyperemia is unaffected by NO synthesis inhibition.

19 lcholine were not attenuated by nitric oxide synthesis inhibition.

20 of exercise, and this was not changed by NO synthesis inhibition.

21 induced COX-2 independently of prostaglandin synthesis inhibition.

22 use of blockers of ET-1 receptors and by NO synthesis inhibition.

23 duction of calreticulin mRNA resists protein synthesis inhibition.

24 culture and that did not increase during DNA synthesis inhibition.

25 Parallel to RNA synthesis inhibition, 8-Cl-Ado was maximally incorporate

26 del of high serum Ang II) or by nitric oxide synthesis inhibition (a model of low serum Ang II).

27 Moreover, protein synthesis inhibition, a feature of the high-altitude pla

28 ng hypothermia as the only cause for protein synthesis inhibition (active, 0.47 +/- 0.08 pmol/mg prot

29 e mature protein) that had identical protein synthesis inhibition activity as compared to native BD1.

30 BD1-G28-5 sFv retained the full protein synthesis inhibition activity of recombinant BD1 and spe

31 nists or postsynaptic 2-arachidonoylglycerol synthesis inhibition again reversed this block.

32 sor and renal vasoconstrictor response to NO synthesis inhibition, although the natriuretic response

33 Differential aspects of DNA synthesis inhibition among cell types are presented and

34 ypoxic ROS and contributed to global protein synthesis inhibition and adaptive ATF4-mediated gene exp

35 Similarly, the protein synthesis inhibition and apoptosis induction correlated

36 in BCR-stimulated cells, leading to protein synthesis inhibition and cell cycle block.

37 8 or 249-265 lack functions of IFN-beta mRNA synthesis inhibition and degradation of PKR.

38 The dose responses for fatty acid synthesis inhibition and DNA synthesis inhibition are si

39 de the first evidence that placental protein synthesis inhibition and endoplasmic reticulum (ER) stre

40 lular pH and calcium manipulation on protein synthesis inhibition and energy failure due to anoxia/ag

41 olar macrophages with endogenous leukotriene synthesis inhibition and enhance this process in leukotr

42 factor alpha (TNF-alpha), the ability of RNA synthesis inhibition and NF-kappaB inactivation to sensi

43 summarize recent findings about triglyceride synthesis inhibition and prevention of progressive disea

44 ases the apoptotic threshold through protein synthesis inhibition and simultaneous production of cera

45 lls from forodesine-induced RNA- and protein-synthesis inhibition and stabilized and increased Mcl-1

46 ecifically discuss their role in the protein synthesis inhibition and the intrinsic pathway of apopto

47 minals show decreased sensitivity to protein synthesis inhibition, and resistance coincides with a de

48 ells in nude mice treated with C75 showed FA synthesis inhibition, apoptosis, and inhibition of tumor

49 for fatty acid synthesis inhibition and DNA synthesis inhibition are similar.

50 on was correlated with the degree of protein synthesis inhibition as measured by autoradiography and

51 competed by an excess of IL-13 in a protein synthesis inhibition assay and confirmed by a clonogenic

52 neck cancer cells, as determined by protein synthesis inhibition assay and confirmed by clonogenic a

53 , resulting in nanomolar potencies in an ATP synthesis inhibition assay.

54 rom 12 to 50 microM in the cell-free protein synthesis inhibition assay.

55 )H-radiolabeled precursors in macromolecular synthesis inhibition assays against MRSA.

56 lls, as determined by clonogenic and protein synthesis inhibition assays.

57 Furthermore, sterol synthesis inhibition blocks Mga2 pathway activation.

58 tein genes occurs in a background of protein synthesis inhibition, but in the course of diapause, a s

59 3' --> 5' exonuclease may contribute to DNA synthesis inhibition by alkylating agents.

60 proposed model for the mechanism of protein synthesis inhibition by aminoglycosides that invokes a d

61 The mechanism of DNA synthesis inhibition by cerulenin is indirect, because e

62 Protein synthesis inhibition by cycloheximide (CHX) treatment in

63 ion by bisindolylmaleimide (BIM) and protein synthesis inhibition by cycloheximide (CX) on basal and

64 DF is selectively inactivated during protein synthesis inhibition by cycloheximide and at a late stag

65 gation of mesangial cell Fas, and by protein synthesis inhibition by cycloheximide.

66 Based on this model for protein synthesis inhibition by DB, and the proposed mechanism o

67 ic pathway activity and the magnitude of DNA synthesis inhibition by FAS inhibitors are increased in

68 The mechanism of protein synthesis inhibition by hypoxia and its circumvention by

69 We also found that hepatocyte DNA synthesis inhibition by IL-1beta was completely antagoni

70 The degree of DNA synthesis inhibition by myeloperoxidase-sufficient neutr

71 (-5) mol/L) was measured before and after NO synthesis inhibition by nitro-L-arginine (LNA, 10(-4) mo

72 window, hours after training, where protein synthesis inhibition can cause amnesia.

73 t what injection time window(s) will protein synthesis inhibition cause spatial memory amnesia?

74 While Hsc70 completely reversed protein synthesis inhibition caused by Hg2+.

75 L-1 reproduced the induction of iNOS and DNA synthesis inhibition caused by TCT and endotoxin.

76 ts into the mode of action, drug uptake, DNA synthesis inhibition, cell cycle effects, and induction

77 Finally, we find that protein synthesis inhibition, cell-cycle arrest, protein kinase

78 revious studies have shown that nitric oxide synthesis inhibition corrects the hyporesponsiveness to

79 Brain cholesterol synthesis inhibition (CSI) at a young age in rats has be

80 hat brief periods of global or local protein synthesis inhibition decrease the synaptic vesicles avai

81 transcriptional level, resulting in protein synthesis inhibition, decreased viral messenger RNA asso

82 Klf13 mRNA was resistant to de novo protein synthesis inhibition, demonstrating that Klf13 is a dire

83 correlate with TRAIL resistance, and protein synthesis inhibition did not sensitize the TRAIL-resista

84 increased biosynthetic activity, and protein synthesis inhibition downstream of mammalian target of r

85 reduction itself also attenuated the protein synthesis inhibition due to anoxia/aglycemia (to 55.6% o

86 measurements were made before and during NO synthesis inhibition during exercise.

87 E-BP1 occurs roughly concurrent with protein synthesis inhibition; during recovery from heat shock re

88 Protein synthesis inhibition experiments confirmed the mechanism

89 alternative interpretations are that protein synthesis inhibition facilitates extinction and that pos

90 s, cases have been reported in which protein synthesis inhibition failed to affect memory consolidati

91 zation of the medium exacerbated the protein synthesis inhibition following anoxia/aglycemia, and sig

92 Moreover, protein synthesis inhibition following early FOS expression resu

93 Although protein synthesis inhibition has been shown to affect long-term

94 ecifically and highly cytotoxic [50% protein synthesis inhibition (IC50) ranging from >0.1 to 13 ng/m

95 neither postsession inactivation nor protein synthesis inhibition impaired context-appropriate respon

96 We show that protein synthesis inhibition impairs the SMN complex, revealing

97 otein expression and was overcome by protein synthesis inhibition in 50% of the resistant cell lines.

98 ent, receptor-mediated and prolonged protein synthesis inhibition in CA1 pyramidal neurons.

99 host protein synthesis, whereas host protein synthesis inhibition in SARS-CoV-mt-infected cells was n

100 GSE treatment also showed DNA synthesis inhibition in starved and EGF-stimulated cells

101 study was to examine the effects of protein synthesis inhibition in the intermediate cerebellum on t

102 ate the beneficial effects of thromboxane A2 synthesis inhibition in the setting of ischemia-reperfus

103 DCs display an unusual resistance to protein synthesis inhibition induced in response to cytosolic ds

104 Triggering cell lysis by peptidoglycan synthesis inhibition is a traditional route for antimicr

105 These results suggest (1) that protein-synthesis inhibition is an important consideration in th

106 Transient protein synthesis inhibition is an important protective mechanis

107 Protein synthesis inhibition is required to sensitize the endoth

108 extinction and that postreactivation protein synthesis inhibition leads to an inability to retrieve t

109 NO synthase blockade and acute prostaglandin synthesis inhibition led to the equalization of GFR, ERP

110 ns were sought with these parameters and DNA synthesis inhibition measured ex vivo by [3H]thymidine i

111 with superimposition of acute prostaglandin synthesis inhibition (meclofenamate, 10 mg/kg IV), renal

112 Transient protein synthesis inhibition, mediated by phosphorylation of the

113 atosis in alcohol-fed mice, but only de novo synthesis inhibition, not sphingomyelin hydrolysis, impr

114 The NO synthesis inhibition observed for raw CPH was reduced af

115 viability was greatly preserved when protein synthesis inhibition occurred after peroxide induction.

116 s of both effects are rapid, with fatty acid synthesis inhibition occurring within 30 min and DNA syn

117 s inhibition occurring within 30 min and DNA synthesis inhibition occurring within 90 min of drug exp

118 arrest at the G0/G1 phase, inhibition of DNA synthesis, inhibition of cyclin D and cyclin E promoter

119 amined the effects of pharmacologic ceramide synthesis inhibition on hepatic PLIN2 expression, steato

120 n accumulation, azithromycin-induced protein synthesis inhibition, oprM (encoding the outer-membrane

121 The effects of GA synthesis inhibition or exogenous GA application differe

122 cells subjected to stresses, such as protein synthesis inhibition or UV irradiation.

123 ensitive electrode, that was abolished by NO synthesis inhibition, or endothelium removal, and reduce

124 -3 activation was also attenuated by protein synthesis inhibition, p53 deficiency, or Bax deficiency,

125 ruption of original consolidation by protein synthesis inhibition (PSI) begun shortly after training.

126 Persistent protein synthesis inhibition (PSI) is a robust predictor of even

127 ed to examine the impact of systemic protein synthesis inhibition (PSI) on the reconsolidation of a c

128 I-labeled ligand binding competition and DNA synthesis inhibition revealed that IGFBP-3 was a more po

129 Protein synthesis inhibition selectively stabilized PTC containi

130 ons of mitochondrial and cytoplasmic protein synthesis inhibition to AG-induced ototoxicity.

131 Using protein synthesis inhibition to measure enzymatic activity, the

132 K activity was always accompanied by protein synthesis inhibition to some extent.

133 e-activated cell sorting analyses showed DNA synthesis inhibition uniformly throughout the S phase af

134 , were studied in vitro by examining protein synthesis inhibition using Vero monkey kidney cells and

135 DNA synthesis inhibition was dependent on the UPR effector P

136 The DNA-binding domain essential for DNA synthesis inhibition was mapped to within 42 amino acid

137 The extent of DNA synthesis inhibition was related to the residual concent

138 Percentages of protein synthesis inhibition were determined by comparing [(35)S

139 op1-mediated DNA single-strand breaks or DNA synthesis inhibition were observed after 1 h exposure to

140 noid signaling, or by 2-arachidonoylglycerol synthesis inhibition, which impairs postsynaptic endocan

141 )O(2) from elevating Nrf2 protein level, RNA synthesis inhibition with actinomycin D failed to do so.

142 he next experiment examined the effect of NE synthesis inhibition with bis(4-methyl-1-homopiperazinyl

143 tensin II hypertensive model of nitric oxide synthesis inhibition with L-NAME.

144 holesterolemic patients before and during NO synthesis inhibition with N(G)-monomethyl-L-arginine (4

145 ience can be disrupted; by contrast, protein synthesis inhibition without prior reminding commonly do