ライフサイエンスコーパス: synthetic biology

1 ich are central to the future development of synthetic biology.

2 great significance in bionanotechnology and synthetic biology.

3 ance of noise analyses for circuit design in synthetic biology.

4 attention to the potential contribution from synthetic biology.

5 of TNA as an artificial genetic polymer for synthetic biology.

6 promise for advancing future applications in synthetic biology.

7 ene and genome transfer in biotechnology and synthetic biology.

8 achievements in the fields of biophysics and synthetic biology.

9 ld be interfaced with other circuits used in synthetic biology.

10 of subcellular compartments in the field of synthetic biology.

11 he "translational filter" and lead to a true synthetic biology.

12 ased architectures for applications in plant synthetic biology.

13 t applications and emerging opportunities in synthetic biology.

14 c methods can be integrated into systems and synthetic biology.

15 o the design of biomaterials and peptides in synthetic biology.

16 biological clockwork, with implications for synthetic biology.

17 networks, modeling and systems biology, and synthetic biology.

18 may be leveraged for future applications in synthetic biology.

19 ments of DNA molecules for biotechnology and synthetic biology.

20 gy and programming new cellular processes in synthetic biology.

21 and (19)F-MRI make them important tools for synthetic biology.

22 h that is the nexus of chemical genomics and synthetic biology.

23 erse applications in mammalian stem cell and synthetic biology.

24 ential biological functions are key goals in synthetic biology.

25 creates new opportunities in force-activated synthetic biology.

26 rials for applications in nanotechnology and synthetic biology.

27 nal and robust genomes, the ultimate goal of synthetic biology.

28 network is a major challenge in cellular and synthetic biology.

29 s is a key topic of both systems biology and synthetic biology.

30 ncrease the repertoire of inducible parts in synthetic biology.

31 create, a major step forward in this area of synthetic biology.

32 e future, as well as the possible impact for synthetic biology.

33 microbial engineering, shaping the field of synthetic biology.

34 lly sized, are critical for advancing fungal synthetic biology.

35 o the field of artificial metalloenzymes and synthetic biology.

36 rce of metabolic modules for applications in synthetic biology.

37 alies, and we explore their implications for synthetic biology.

38 sive engineering efforts for applications in synthetic biology.

39 nto living organisms is a major challenge in synthetic biology.

40 ial provided by genome engineering for plant synthetic biology.

41 ising approach for metabolic engineering and synthetic biology.

42 ting their architectures for applications in synthetic biology.

43 roved protein production and developments in synthetic biology.

44 s is one of the foundational technologies of synthetic biology.

45 ogs and predict host-circuit interactions in synthetic biology.

46 terials to integrated biophysical models for synthetic biology.

47 vanced the fields of genetic engineering and synthetic biology.

48 are a good target for reengineering through synthetic biology.

49 stems of gene expression is instrumental for synthetic biology.

50 ing and manipulating microbial metabolism by synthetic biology.

51 also being exploited in multiple contexts in synthetic biology.

52 analogues of membrane proteins have advanced synthetic biology.

53 of novel and more functional protocells for synthetic biology.

54 increasingly important tool in molecular and synthetic biology.

55 DNA assembly forms the cornerstone of modern synthetic biology.

56 ns in biomolecular design, biotechnology and synthetic biology.

57 eactions that have potential applications in synthetic biology.

58 se applications in molecular programming and synthetic biology.

59 diversity by combinatorial biosynthesis and synthetic biology.

60 reat promise to advance the growing field of synthetic biology.

61 e findings have implications in the field of synthetic biology.

62 nanostructure-based molecular circuitry for synthetic biology.

63 tion in fields ranging from drug delivery to synthetic biology.

64 artmentalization, at the core of systems and synthetic biology.

65 ction is now a standard design principle for synthetic biology(2,3).

66 Using principles of synthetic biology, advances in immunology, and genetic e

67 Synthetic biology aims to develop engineering-driven app

68 This might be considered a synthetic biology analog of molecular signal release and

69 remains a formidable challenge in mammalian synthetic biology and a desirable asset in gene therapy

70 erable potential for applications throughout synthetic biology and bio-manufacturing as they are able

71 design of regulatory biological circuits for synthetic biology and biomedicine.

72 way for use of the 3-HP-inducible system in synthetic biology and biotechnology applications.

73 ally useful gene regulatory tools for use in synthetic biology and biotechnology fields.

74 s, and promote a more general use of CFPS in synthetic biology and biotechnology.

75 halo-metabolites in living cultures.Coupling synthetic biology and chemical reactions in cells is a c

76 manner has great potential for a variety of synthetic biology and compound screening applications.

77 e bacterial cell cycle is a useful asset for synthetic biology and DNA-replication studies in particu

78 present an unrealized source of reagents for synthetic biology and for characterizing cellular transc

79 ill become essential for further progress in synthetic biology and in the development of virtual orga

80 anism-specific regulatory parts, fragmenting synthetic biology and metabolic engineering into host-sp

81 mes and other BMCs for applications in plant synthetic biology and metabolic engineering is understan

82 Synthetic biology and metabolic engineering seek to re-e

83 of protein interdependency in the context of synthetic biology and metabolic engineering, and points

84 ed for many applications at the interface of synthetic biology and metabolic engineering.

85 tate future applications of QS-regulation in synthetic biology and metabolic engineering.

86 , from traditional cloning methods to modern synthetic biology and molecular diagnostics protocols.

87 al. (2016) have exploited recent advances in synthetic biology and molecular engineering to deliver a

88 les match a diverse range of applications in synthetic biology and nanomaterials.

89 gn of diverse DNA binding factors useful for synthetic biology and other purposes.

90 Advances in synthetic biology and our understanding of the rules of

91 elds such as structural biology, biophysics, synthetic biology and photonics.

92 -of-concept experiments have applications in synthetic biology and potentially broad implications for

93 Genetic code expansion is a key objective of synthetic biology and protein engineering.

94 The newly emerged discipline of synthetic biology and related molecular engineering appr

95 We propose this combination of synthetic biology and scalable, point-of-care sensing ha

96 Here, we provide a brief history of plant synthetic biology and significant recent examples of thi

97 an important role in metabolic engineering, synthetic biology, and biocatalysis, but it has rarely b

98 an important tool in metabolic engineering, synthetic biology, and biocatalysis.

99 g diverse applications in molecular biology, synthetic biology, and biotechnology.

100 d products (e.g., CRISPR, gene drives, RNAi, synthetic biology, and genetically modified [GM] insects

101 w that an approach combining bioinformatics, synthetic biology, and heterologous gene cluster express

102 hen introduce several concepts that underpin synthetic biology, and show how generic parts are identi

103 ing translation-reprogramming mechanisms for synthetic biology, and they establish -1 PRF switches as

104 d has been widely applied in genome editing, synthetic biology, and transcriptional modulation in cel

105 of DNA sequences are currently available for synthetic biology applications and technologies for larg

106 this technology opens new opportunities for synthetic biology applications due to the versatility of

107 ks and could provide an engineering point in synthetic biology applications.

108 complex megadimensional datasets, including synthetic biology applications.

109 e range of opportunities to develop advanced synthetic biology applications.

110 roadening the potential use of biosensors in synthetic biology applications.

111 entially very advantageous for biotechnology/synthetic biology applications.

112 onal reprogramming of cellular processes for synthetic biology applications.

113 l basis for developing threshold devices for synthetic biology applications.

114 oteins for drug development and mirror-image synthetic biology applications.

115 hampering the design of engineered genes for synthetic biology applications.

116 th genetic analysis of gene function and for synthetic biology applications.

117 interaction specificity for a broad range of synthetic biology applications; more generally, our resu

118 CRISP-Disp will facilitate synthetic-biology applications and enable the elucidatio

119 es will eventually succeed, I suggest that a synthetic biology approach - moving free-living nematode

120 The 4 x 4 array derived by this bottom-up synthetic biology approach can detect grey-scale images

121 Here, we take a synthetic biology approach to decipher the complexity of

122 hanisms of filament assembly, we have used a synthetic biology approach to reconstitute, in a nonnati

123 Here we describe a synthetic biology approach to the study of neural circui

124 nant protein production by P. pastoris and a synthetic biology approach to this industrial host.

125 Here we have developed a new synthetic biology approach, combinatorial supertransform

126 nimal models, pharmacologic inhibitors and a synthetic biology approach, here we show that the small

127 ieved more efficiently through adoption of a synthetic biology approach.

128 top-bottom leaf patterning and from a novel synthetic biology approach.

129 To overcome this barrier, we developed a synthetic-biology approach based on a technique known as

130 Here, we use a synthetic-biology approach to assemble patterned materia

131 Synthetic biology approaches achieving the reconstructio

132 As synthetic biology approaches are extended to diverse app

133 The emergence of synthetic biology approaches for cellular engineering is

134 metabolons offers opportunities to optimize synthetic biology approaches for efficient production of

135 and this is followed by a discussion of how synthetic biology approaches might be used to create new

136 ess the productivity of CAM crops, while new synthetic biology approaches need to be developed for CA

137 ortunity to incorporate advanced systems and synthetic biology approaches to create cancer therapeuti

138 , Torggler et al. (2016) leverage innovative synthetic biology approaches to dissect the spatiotempor

139 natural products using in vitro and in vivo synthetic biology approaches.

140 We envision future applications in complex synthetic biology architectures, gene therapy and trace-

141 r advanced metabolic engineering and applied synthetic biology are considered, as are the issues that

142 aboratory and transformative applications of synthetic biology are still in their infancy.

143 Two of the many goals of synthetic biology are synthesizing large biochemical sys

144 Emerging technologies, such as genomics and synthetic biology, are enabling new ways for discovering

145 ould both provide tools for biocatalysis and synthetic biology, as well as guide efforts to uncover n

146 s and their application in developmental and synthetic biology, as well as in biomedical research.

147 Synthetic biology aspires to construct natural and non-n

148 merous applications in biomedicine including synthetic biology, assisted fertilization, and drug/gene

149 A combination of traditional and synthetic biology-based heterologous expression efforts

150 istance with Isomap and Laplacian Eigenmaps, synthetic biology biobircks are successfully visualized

151 eaction cascades are of great importance for synthetic biology, biochemistry and bioengineering.

152 of technological advancements in systems and synthetic biology, biomaterials engineering, and traditi

153 s9 in basic biology, translational medicine, synthetic biology, biotechnology, and other fields.

154 l of membrane proteins in nanotechnology and synthetic biology by manipulating global bilayer propert

155 bed as ultrasensitive, and can be applied in synthetic biology by using various techniques including

156 iagnostics in the field and demonstrates how synthetic biology can be used to develop diagnostic tool

157 Within the scope of synthetic biology, carboxysomes and other BMCs hold even

158 nells thus enable a more modular creation of synthetic biology cascades, an essential step towards th

159 aders of the international plant science and synthetic biology communities, including inventors, deve

160 robial community levels that show promise in synthetic biology contexts.

161 By extracting biobricks from synthetic biology database Registry of Standard Biologic

162 As crowdsourcing-based synthetic biology databases face similar data quality is

163 ich could help to assess crowdsourcing-based synthetic biology databases' quality, and make biobricks

164 , the current work illustrates its power for synthetic biology design, and thus has wider significanc

165 SBOL represents synthetic biology designs in a community-driven, formali

166 ole, these models inform QS observations and synthetic biology designs.

167 Synthetic biology devices, such as engineered gene circu

168 However, plant synthetic biology efforts have been hampered by a dearth

169 This size limits large-scale synthetic biology efforts in yeasts.

170 Successful synthetic biology efforts rely on conceptual and experim

171 r aryl O-demethylation and as a component of synthetic biology efforts to valorize previously underus

172 Recent developments in synthetic biology enable one-step implementation of enti

173 Synthetic biology enables the construction of genetic ci

174 This key process remains a bottleneck in synthetic biology, especially for genome engineering str

175 on, modern methods of directed evolution and synthetic biology, especially those effecting changes in

176 ity-driven standard, SBOL will be updated as synthetic biology evolves to provide specific capabiliti

177 Here, we describe current efforts in synthetic biology, focusing on the translation of promis

178 es are extensively used in biotechnology and synthetic biology for assembly and rearrangement of DNA

179 This work addresses a current need in synthetic biology for simplified and robust methods to c

180 This work establishes a synthetic biology framework for endowing mammalian cells

181 This work provides a synthetic biology framework to approach cell fate determ

182 NA plays a significant role in the fields of synthetic biology, functional genomics and bioengineerin

183 and easy adaptation for other uses, such as synthetic biology, genetic screens, and CRISPR-Cas9.

184 Synthetic biology has become a widely used technology, a

185 Modern synthetic biology has been reinvented as an engineering

186 A longstanding goal of synthetic biology has been the programmable control of c

187 The advent and growth of synthetic biology has demonstrated its potential as a pr

188 The new field of plant synthetic biology has emerged in recent years and is exp

189 Synthetic biology has enabled the production of many val

190 Synthetic biology has focused on engineering microbes to

191 Synthetic biology has seen an explosive growth in the ca

192 Recent developments in synthetic biology have positioned lactic acid bacteria (

193 Recent advances in synthetic biology have provided tools to efficiently con

194 mical pathways that provide tools needed for synthetic biology in both plant and microbial systems.

195 In this short article, I argue why synthetic biology in conjunction with the quantitative s

196 The present review considered the role of synthetic biology in sustaining biosensor technology, re

197 We have designed a novel synthetic biology 'in situ epistasis' analysis in which

198 An important challenge in synthetic biology involves the de novo design of RNA mod

199 Synthetic biology is advancing the design of genetic dev

200 Synthetic biology is characterized by the development of

201 Synthetic biology is increasingly used to develop sophis

202 An important goal in synthetic biology is the assembly of biomimetic cell-lik

203 One major objective of synthetic biology is the bottom-up assembly of minimalis

204 A challenge of synthetic biology is the creation of cooperative microbi

205 One promise of synthetic biology is the creation of genetic circuitry t

206 One fundamental challenge in synthetic biology is the lack of quantitative tools that

207 One of the goals of synthetic biology is to build regulatory circuits that c

208 The central goal of synthetic biology is to create new life forms and functi

209 A defining goal of synthetic biology is to engineer cells to coordinate tas

210 A central goal of synthetic biology is to implement diverse cellular funct

211 A central goal of molecular and synthetic biology is to uncover design principles linkin

212 rs (CRISPR-TRs) have transformed the current synthetic biology landscape by allowing specific activat

213 We cite specific examples from the synthetic biology literature that illustrate these princ

214 l therapies requires advances in immunology, synthetic biology, manufacturing processes, and governme

215 The results indicate that synthetic biology may be preferred over nanotechnology a

216 This work also indicates that synthetic biology may be utilized to create de novo TPs

217 ization, and, with examples, demonstrate how synthetic biology may maximize CO2 uptake within and abo

218 s of potential applications in the fields of synthetic biology, medicine, molecular computation, etc.

219 n a hybrid method that includes drug design, synthetic biology, metabolomics and pharmacological assa

220 Here we present a synthetic biology method to engineer histones that bear

221 however, has been challenging, because most synthetic biology methods have focused solely on rewirin

222 As de novo gene synthesis and synthetic biology methods permeate many biotechnology sp

223 ent very promising opportunities for further synthetic biology modification and for a variety of biot

224 pate these regulators will find broad use as synthetic biology moves beyond parts engineering to the

225 The combination of cell-free synthetic biology, nanodisc-technology and non-covalent

226 In the emerging field of synthetic biology, noise and context dependency are amon

227 Synthetic biology offers the potential to expand communi

228 ships and coupled to the emerging methods of synthetic biology, offers scope for the development of n

229 Synthetic Biology Open Language (SBOL) Visual is a graph

230 The library was formatted using the Synthetic Biology Open Language, an emerging standard de

231 the design of next-generation DNA pores for synthetic biology or biomedicine.

232 ary property could be engineered by adopting synthetic biology or biomimetic chemistry to obtain tail

233 o develop novel peptides for applications in synthetic biology or nanotechnology.

234 ostulate that XNA could be used to safeguard synthetic biology organisms by storing genetic informati

235 the localized feedback model, we developed a synthetic biology platform based on mammalian cells expr

236 Here, we present a synthetic biology platform for rapid construction and op

237 rovide a sound base for the development of a synthetic biology platform for the production of bioacti

238 This synthetic biology platform resolves important practical

239 I diTPS functions in plants, and may promote synthetic biology platforms for a broader spectrum of di

240 S) enzymes continue to hold great promise as synthetic biology platforms for the production of novel

241 ng of plant and microbial metabolism for the synthetic biology platforms of tomorrow will require pre

242 esting biosensor constructs, developed using synthetic biology principles, in different bacterial gen

243 ymatic activity, we launched a combinatorial synthetic biology program in which we combined CYP716Y1

244 versity and expand the toolbox available for synthetic biology programmes for sustainable production

245 e, extendable workflow management system for synthetic biology projects with entry points for oligos

246 Because cI is used in so many synthetic biology projects, the new set of variants will

247 Plant synthetic biology promises immense technological benefit

248 The new field of synthetic biology promises to change health care, comput

249 of advanced molecular tools and the rise of synthetic biology provide an opportunity to expedite the

250 Synthetic biology provides an opportunity for the constr

251 ge may be manipulated for genome editing and synthetic biology purposes.

252 typically are missing from considerations of synthetic biology R&D-related risk and containment.

253 The past decade of synthetic biology research has witnessed numerous advanc

254 Also falling under the synthetic biology rubric and discussed here is the nasce

255 Synthetic biology seeks to create new biological systems

256 Synthetic biology seeks to extend approaches from engine

257 As one of its goals, synthetic biology seeks to increase the number of buildi

258 Synthetic biology should be employed for de novo design

259 ges in agriculture, human health and energy, synthetic biology should develop predictive design princ

260 oswitches have gained attention as tools for synthetic biology, since they enable researchers to repr

261 Here, we review advances in synthetic biology, single cell genomics, and multiscale

262 t recent advances made in the field of plant synthetic biology, specifically in genome editing, trans

263 discuss notable challenges that the field of synthetic biology still faces in achieving reliable and

264 f Saccharomyces cerevisiae as a platform for synthetic biology, strain engineering remains slow and l

265 One promising approach is to use synthetic biology techniques to engineer simple genetic

266 laccase on the surface of yeast cells using synthetic biology techniques.

267 To realize the full potential of plant synthetic biology, techniques are required that provide

268 Synthetic genetics is a subdiscipline of synthetic biology that aims to develop artificial geneti

269 cations in basic research, biotechnology and synthetic biology that involve the multistep engineering

270 remediation by comparing nanotechnology and synthetic biology to conventional remediation methods.

271 cted technologies of genetic engineering and synthetic biology to create entertaining stories.

272 networks, but also to perform sophisticated synthetic biology to develop innovative engineered stem

273 Applying synthetic biology to engineer gut-resident microbes prov

274 y, we give a long-term vision for the use of synthetic biology to engineer immune cells as a general

275 es a methodology for leveraging the tools of synthetic biology to exploit the natural propensity for

276 ish a library of devices that can be used in synthetic biology to facilitate modular circuit design.

277 Here we use bioinformatics and synthetic biology to mine the human microbiota for N-acy

278 Significant advances have been made in synthetic biology to program information processing capa

279 s, this review describes the emerging use of synthetic biology to recombinantly reconstitute plant te

280 The synthetic biology toolbox lacks extendable and conformat

281 approach will be a valuable addition to the synthetic biology toolkit, facilitating the understandin

282 signed to combat cancer, focusing on how new synthetic biology tools are providing potential ways to

283 eins inducible by small molecules are useful synthetic biology tools as sensors and switches.

284 Using synthetic biology tools combined with long-read DNA sequ

285 Synthetic biology tools provide novel functionality to c

286 In this study, we review synthetic biology tools that are being applied to effect

287 This study offers new synthetic biology tools to program spatial structures.

288 Synthetic biology uses living cells as molecular foundri

289 Synthetic biology was founded as a biophysical disciplin

290 With the rapid advancement of synthetic biology, we can now engineer and equip immune

291 metabolism, in combination with advances in synthetic biology, we can now tailor plant lipids for de

292 To fully realize the promise of synthetic biology, we must be aware of life's unique pro

293 stitute an interesting potential resource in synthetic biology, where engineered RNATs could prove to

294 Modern methods of synthetic biology, whereby increasingly large sequences

295 studies in DNA nanotechnology, genetics and synthetic biology, which all require thousands of these

296 Marrying synthetic biology with synthetic chemistry provides a po

297 rogram cellular behaviour is a major goal of synthetic biology, with applications in health, agricult

298 Synthetic biology, with its rational and short design-to

299 ic capabilities for different aspects of the synthetic biology workflow.

300 ize libraries of genetic parts to facilitate synthetic biology workflows.