ライフサイエンスコーパス: synthetic pathway

1 was synthesized through an efficient 13-step synthetic pathway.

2 ynthesis in a highly convergent and flexible synthetic pathway.

3 n recycling purine groups from the polyamine synthetic pathway.

4 complished through exploitation of a related synthetic pathway.

5 talyses the first, rate-limiting step in the synthetic pathway.

6 synthase, a pivotal enzyme in the early GSL synthetic pathway.

7 way with the cholesterol catabolic bile acid synthetic pathway.

8 onvergence of PPARalpha with the cholesterol synthetic pathway.

9 s the first committed step of the fatty acid synthetic pathway.

10 ve or negative regulators of the siderophore synthetic pathway.

11 3z, sidearm buildup was also employed in the synthetic pathway.

12 stimulation of a normal but under-utilized, synthetic pathway.

13 ated S-adenosylmethionine from the polyamine synthetic pathway.

14 e host for purines since they lack a de novo synthetic pathway.

15 ures of intermediates and a stereocontrolled synthetic pathway.

16 to determine the site of action in the PGD2 synthetic pathway.

17 ta and reference texts are available on this synthetic pathway.

18 ase (NMNAT) is a conserved enzyme in the NAD synthetic pathway.

19 oxo-3,4-dehydroxyneomajucin (ODNM) along the synthetic pathway.

20 for transforming TCP based on an immobilized synthetic pathway.

21 lic antimalarial agent that derived from the synthetic pathway.

22 o manno epimerization at a late stage of the synthetic pathway.

23 ylase (TH), a rate-limiting enzyme in the CA synthetic pathway.

24 aphthyridinediones were prepared via a novel synthetic pathway.

25 ing the strict specificity of the fatty acid synthetic pathway.

26 itical regulatory contribution to the serine synthetic pathway.

27 form of a stable prehapten through a 5 step synthetic pathway.

28 of BH4 salvage/reduction versus de novo BH4 synthetic pathways.

29 o seven urea linkages were made by iterative synthetic pathways.

30 novel analogues were prepared by two general synthetic pathways.

31 se phosphate shunt, and lipogenic and sterol synthetic pathways.

32 nt antibiotics that act to inhibit bacterial synthetic pathways.

33 cts in two key genes in different methionine synthetic pathways.

34 edirect precursor molecules into alternative synthetic pathways.

35 hips between the degradation, recycling, and synthetic pathways.

36 those compounds obtained through each of the synthetic pathways.

37 to either the P1 or P1' residue required new synthetic pathways.

38 mbinant microorganisms containing artificial synthetic pathways.

39 NMR spectroscopy, and additional independent synthetic pathways.

40 ts role in early steps of both wax and cutin synthetic pathways.

41 otein oxygenases involved in natural product synthetic pathways.

42 Fatty acid synthetic pathway activity and the magnitude of DNA synt

43 etylglucosamine, a product of the hexosamine synthetic pathway, acts as a substrate at an early stage

44 This synthetic pathway allowed for the creation of hydrogel m

45 The lipid synthetic pathway also provides precursors for protein m

46 tolerance to salinity and hypoxia makes its synthetic pathway an interesting target for metabolic en

47 This review concentrates on the phospholipid synthetic pathway and discusses recent data on the synth

48 of genes in the leaf involved in the sucrose synthetic pathway and photosynthesis, such as Calvin cyc

49 The highly convergent nature of our synthetic pathway and the flexibility of the modular syn

50 ifran analogs prepared using newly developed synthetic pathways and evaluated as agonists for GPR109a

51 lytical scientist as well as inspiration for synthetic pathways and innovative research into next-gen

52 tured HOK express enzymes of the epinephrine synthetic pathway, and generate epinephrine.

53 lecular tools for several key enzymes in the synthetic pathway are becoming available.

54 ions that patients with disorders in the PyN synthetic pathway are not overtly immunodeficient milita

55 The described synthetic pathways are based on a highly anti-diastereos

56 The two synthetic pathways are connected by prostaglandin E2 (PG

57 ring offers an alternative approach in which synthetic pathways are engineered into user-friendly hos

58 These synthetic pathways are frequently upregulated in cancer

59 Biotin synthetic pathways are readily separated into two stages

60 The synthetic pathways are sensitive to metal radius.

61 ere enriched in specific metabolic and lipid synthetic pathways, as well as the draper/Megf10 and Mer

62 In this regard, synthetic pathways based on thiolase enzymes to catalyze

63 Cell-free synthetic pathway biotransformation (SyPaB) is the imple

64 mparable complexity, which are united in the synthetic pathway by conjugate addition of a nucleophili

65 amide generation is derived from the de novo synthetic pathway by coordinate activation of SPT and ce

66 creasing vesicular glutamate, access to this synthetic pathway by exogenously applied glutamine to ne

67 s requirement provided the currently complex synthetic pathway can be simplified.

68 In theory, hybrid polyketide synthetic pathways can be constructed through the ration

69 Furthermore, the synthetic pathways can be used to construct pancratistat

70 izes and the regulation of the two bile acid synthetic pathways (classic, via cholesterol 7alpha-hydr

71 However, synthetic pathway construction in cyanobacteria is still

72 eered 13 strains of Yarrowia lipolytica with synthetic pathways converting glycolytic NADH into the l

73 An intermediate in the synthetic pathway, Delta(23,24)-dehydroascomycin, was li

74 Astrocyte synthetic pathways, dependent on glutathione, are involv

75 trates the efficacy of ensemble modeling for synthetic pathway design.

76 that could afford both the precursors of the synthetic pathways eventually leading to RNA and to the

77 nuatum, a member of the genus that lacks the synthetic pathway for beta-Ala betaine.

78 Herein a fundamentally different synthetic pathway for bioalcohol production at 70 degree

79 id excipients and open a novel and effective synthetic pathway for derivation of phenyl alcohols.

80 ndocytic signals, we were able to generate a synthetic pathway for efficient transport of a reporter

81 In one example, we divided the synthetic pathway for the acetylated diol paclitaxel pre

82 This method provides an efficient synthetic pathway for the combinatorial synthesis of con

83 ene-based molecular receptors is a important synthetic pathway for the elaboration of more sophistica

84 Because the synthetic pathways for both molecules are complex, in ad

85 Establishing efficient synthetic pathways for microbial production of biochemic

86 Engineering synthetic pathways for production of alpha-methyl acids

87 Several synthetic pathways for the production of liquid biofuels

88 hallenging functional groups and opens novel synthetic pathways for the utilization of renewable carb

89 nature of the involved chemistries sets the synthetic pathway free from any functional group protect

90 We uncovered a placental 5-HT synthetic pathway from a maternal tryptophan precursor i

91 alization in cellular organelles can isolate synthetic pathways from competing pathways, and provide

92 an efficient method for building large-scale synthetic pathways from standardized, reusable component

93 ssion of the first enzyme in the glutathione synthetic pathway [glutamate cysteine ligase (GCL)] were

94 key regulatory enzyme in the de novo purine synthetic pathway, glutamine PRPP amidotransferase (also

95 sing the possibility that loss of the purine synthetic pathway had rendered 10-CHO-THF dispensable in

96 H biosynthesis and provide evidence that the synthetic pathway has similarities to that established f

97 hain acyl-ACPs, the intermediates of the UFA synthetic pathway have been followed in vivo for the fir

98 The synthetic pathways have been developed to prepare 7-, 8-

99 Classical synthetic pathways, i.e., anionic polymerization, coordi

100 We now identify a novel retinoid synthetic pathway in differentiating F9 cells that resul

101 ion of an exogenous stepwise O-glycosylation synthetic pathway in E. coli In addition, we have determ

102 ion of an exogenous stepwise O-glycosylation synthetic pathway in E. coli.

103 investigated the keratinocyte catecholamine synthetic pathway in response to acute trauma.

104 lighted the role of the polyphosphoinositide synthetic pathways in activated cells.

105 t of new tools and approaches to engineering synthetic pathways in microbial hosts for chemical produ

106 , suggesting a different regulation of these synthetic pathways in the adrenal cortex inner zone duri

107 notyped for functional variants on vitamin D synthetic pathway including GC (rs4588, rs7041, rs22020,

108 ithin the de novo fatty acid and cholesterol synthetic pathways, including sterol regulatory element

109 oxylase (ODC), a key enzyme of the polyamine synthetic pathway, increased cellular aggregates and inc

110 tures and a mouse model and showed that this synthetic pathway increases free fatty acid beta-oxidati

111 tamine (polyQ) proteins promote the spermine synthetic pathway, increasing polyQ-aggregation and cell

112 The reconstructed synthetic pathways indicate that small radicals and form

113 Here, a simple synthetic pathway integrates gold quantum dots within a

114 ethionine metabolism-related and glutathione synthetic pathway intermediates, including S-adenosylmet

115 of the use of these reactions to devise new synthetic pathways, investigate reaction mechanisms, and

116 The alternative synthetic pathway involves an initiator containing a mal

117 A two-step synthetic pathway involving decyanation chemistry for th

118 Key to the success of this synthetic pathway is a Pd-catalyzed C(sp(3))-H arylation

119 ide formation from IMP in the de novo purine synthetic pathway is carried out by two isoforms of the

120 The taurine synthetic pathway is proposed to be incomplete in astroc

121 This large synthetic pathway is shared by virtually all salmonellae

122 The synthetic pathway is suitable for preparation and biolog

123 The type II fatty acid synthetic pathway is the principal route for the product

124 ase (TPH), the first enzyme in the melatonin synthetic pathway, is expressed rhythmically under the c

125 ding suppression of the intermediates in the synthetic pathway leading to expression of the T cell co

126 The synthetic pathway leads to platinum nanoparticles of app

127 B12 in living forms, we suggest that the B12 synthetic pathway may have evolved to allow anaerobic fe

128 Activity of the fatty acid synthetic pathway measured by labeling of six surgical s

129 Although the unsaturated fatty acid (UFA) synthetic pathway of Escherichia coli is the prototype o

130 The anaerobic unsaturated fatty acid synthetic pathway of Escherichia coli requires two speci

131 protein (ACP)) synthase I/II (FabF/B) in the synthetic pathway of fatty acids.

132 While studying the bile acid synthetic pathway of hamsters, we discovered an NADP+-de

133 e candidate substance that emanates from the synthetic pathway of melanin that plays a key role in re

134 This paper aims to elucidate whether the synthetic pathway of Melatonin in Saccharomyces and non-

135 The synthetic pathway of morphine in the opium poppy has bee

136 ression, suggesting that the thyroid hormone synthetic pathway of the mouse could be dissociated into

137 In particular, we present a plausible synthetic pathway of the tetramers and their further com

138 ic mesolimbic activity, and (2) in controls, synthetic pathways of this neurocircuitry maintain suffi

139 The glycan synthetic pathways of this pathogen are of great interes

140 is illustrated with several case studies: a synthetic pathway problem of signaling regulation, a two

141 erimental methods testedincluded the use of "synthetic pathways" (random sets of genes) to estimate p

142 merization, plant metabolic engineering, and synthetic pathway reconstruction were demonstrated for v

143 have highlighted the relevance of the serine synthetic pathway (SSP), which consists of three success

144 ia coli BioC protein as the initiator of the synthetic pathway that forms the pimeloyl moiety of biot

145 OX-2) is a cellular enzyme in the eicosanoid synthetic pathway that mediates the synthesis of prostag

146 The next frontier is to create synthetic pathways that adapt to changing environments.

147 vides the experimentalist with complimentary synthetic pathways that afford either the pyrimidin-7-on

148 Synthetic pathways that are able to systematically produ

149 hotochemistry of TiO(2) and suggests general synthetic pathways that are the result of the ability to

150 This review focuses on those synthetic pathways that build up a polymer chain from et

151 sively investigated, together with plausible synthetic pathways that might have led, abiotically, to

152 lism into energy production rather than into synthetic pathways that require hexosamines.

153 matic specificity within the N-linked glycan synthetic pathway, the sequencing results of GlycoSeq we

154 steps in the classic and alternate bile acid synthetic pathways, thereby reducing the hepatic bile ac

155 he substrate for the next enzyme in the dTTP synthetic pathway, thymidylate synthase.

156 The synthetic pathway to 2 was optimized from seven to five

157 Finding a synthetic pathway to artificial analogs of nacre and bon

158 Here we report a new and simple synthetic pathway to form ordered, hollow carbon nitride

159 We redesigned the DAP synthetic pathway to generate L,L-NSDAP and other L,L-NS

160 This work suggests a simple synthetic pathway to high surface-area, low-density nano

161 of xenobiotics and in a recently constructed synthetic pathway to produce D-glucaric acid, a "top val

162 and our approach provides a straightforward synthetic pathway to such compounds.

163 A new synthetic pathway to the 4,5-diarylphenanthrenes 8 havin

164 Here, we describe the first de novo synthetic pathway to this exceptionally rare C5-nor stem

165 Herein, we report a general synthetic pathway to various shapes of three-dimensional

166 Synthetic pathways to (salcy)CoX (salcy = N,N'-bis(3,5-d

167 Investigations of potential synthetic pathways to 1 initially utilized as starting m

168 New synthetic pathways to 11H-benzo[b]fluoren-11-ols, 1H-cyc

169 In this report, we present synthetic pathways to a variety of SF5CF2-substituted co

170 Synthetic pathways to complex meroterpenes derived from

171 s of glycosidic linkage as defined by glycan synthetic pathways to eliminate improbable glycan struct

172 the structure of the helical pores indicate synthetic pathways to helical pores with bioinspired fun

173 Here, we show that targeting synthetic pathways to peroxisomes can increase the produ

174 New synthetic pathways to the 5H-pyrido[3',4':4,5]pyrrolo[2,

175 tic properties and reveals a straightforward synthetic pathway toward novel energetic 1,2,4-triazole

176 A simple and unpredicted synthetic pathway toward racemic and scalemic tetrahydro

177 The synthetic pathways used for the syntheses of dicarba-clo

178 future from an evolving forward analysis of synthetic pathways, used in diversity-oriented synthesis

179 n of microsomal and peroxisomal glycerolipid synthetic pathways, using D-[3-(3)H, U-(14)C]glucose as

180 The synthetic pathway was unique in that the major product,

181 The synthetic pathway was via Wittig-Horner coupling of the

182 n to enhance muscle regeneration and protein synthetic pathways, we asked whether high levels of musc

183 Using multiple synthetic pathways, we probed diverse substitutions of t

184 ing for promiscuous aldehyde dehydrogenases, synthetic pathways were constructed to produce both C5 a

185 rity of genes involved in fructan and starch synthetic pathways were positively correlated with sucro

186 This synthetic pathway, which avoids intermediate purificatio

187 ovo DNA synthesis approach for engineering a synthetic pathway with microchip-synthesized oligonucleo