ライフサイエンスコーパス: systemic autoimmune disease

1 es may develop, and perhaps be prevented, in systemic autoimmune disease.

2 ht to trigger the pathogenic consequences of systemic autoimmune disease.

3 specificities in sera from 58 patients with systemic autoimmune disease.

4 The MHC exerts an important influence on systemic autoimmune disease.

5 s that affect the priming and progression of systemic autoimmune disease.

6 and function and that H2S deficiency led to systemic autoimmune disease.

7 entral to the pathogenesis of this prototype systemic autoimmune disease.

8 on inhibits inflammatory pathology caused by systemic autoimmune disease.

9 arthritis as well as other manifestations of systemic autoimmune disease.

10 CD4+ T cells in both spontaneous and induced systemic autoimmune disease.

11 Rheumatoid arthritis is a systemic autoimmune disease.

12 o the contribution of Toll-like receptors in systemic autoimmune disease.

13 within the kappa locus may be shared with a systemic autoimmune disease.

14 athway may be related to the pathogenesis of systemic autoimmune disease.

15 ns, and may drive the autoimmune response in systemic autoimmune disease.

16 and elements necessary for the initiation of systemic autoimmune disease.

17 ich is the cellular signature of a subset of systemic autoimmune diseases.

18 sis include nuclear autoantigens targeted in systemic autoimmune diseases.

19 mic lupus erythematosus (SLE) and many other systemic autoimmune diseases.

20 mmune responses to viral pathogens and other systemic autoimmune diseases.

21 epresent a large fraction of autoantigens in systemic autoimmune diseases.

22 mains, with PCS scores in the range of other systemic autoimmune diseases.

23 nts useful in rheumatoid arthritis and other systemic autoimmune diseases.

24 ipheral B-cell development in the context of systemic autoimmune diseases.

25 ies the production of many autoantibodies in systemic autoimmune diseases.

26 likely play a key role in the development of systemic autoimmune diseases.

27 ed not only organ-specific diseases but also systemic autoimmune diseases.

28 arding occupational exposures that may cause systemic autoimmune diseases.

29 he treatment of multiple sclerosis and other systemic autoimmune diseases.

30 rol sera and with sera from 21 patients with systemic autoimmune diseases.

31 city in relation to disease heterogeneity in systemic autoimmune diseases.

32 n why intracellular antigens are targeted in systemic autoimmune diseases.

33 ntigen targeted by autoantibodies in several systemic autoimmune diseases.

34 l remission from organ-specific-, as well as systemic, autoimmune diseases.

35 Sera from 639 subjects (417 patients with systemic autoimmune disease, 13 with sarcoidosis, 44 wit

36 Rheumatoid arthritis (RA) is the most common systemic autoimmune disease, affecting approximately 1%

37 The induction of systemic autoimmune disease after virus infection in Sig

38 One patient had a preexistent systemic autoimmune disease and another's was later diag

39 daptive immune systems in the development of systemic autoimmune disease and explain the preponderanc

40 terial disease in allograft vasculopathy and systemic autoimmune diseases and involve pathogenic Abs

41 ssociations have also been reported in other systemic autoimmune diseases and suggest that there are

42 ations between occupation and death from any systemic autoimmune disease, and from RA, SLE, and syste

43 ut rapidly developed severe lymphadenopathy, systemic autoimmune disease, and thrombocytopenia.

44 beta T cell-dependent mechanisms can induce systemic autoimmune disease, and to address the roles of

45 (5 for hematologic malignant diseases, 4 for systemic autoimmune diseases, and 2 following organ tran

46 phatidylcholine (LPC) in atherosclerosis and systemic autoimmune disease are well recognized, LPC has

47 Systemic autoimmune diseases are a genetically complex,

48 Systemic autoimmune diseases are characterized by specif

49 tigens targeted across the spectrum of human systemic autoimmune diseases are efficiently cleaved by

50 d concomitant thrombosis risk factors and/or systemic autoimmune disease at the time of thrombosis.

51 stem, and mice lacking TAM receptors develop systemic autoimmune diseases because of inefficient nega

52 autoantigens targeted across the spectrum of systemic autoimmune diseases (but not nonautoantigens) a

53 ated the requirements for the development of systemic autoimmune disease by using bone marrow chimera

54 Although systemic autoimmune diseases can be accompanied by multi

55 rome has become the prototype for an aseptic systemic autoimmune disease caused by a known environmen

56 Rheumatoid arthritis (RA) is a prevalent systemic autoimmune disease, caused by a combination of

57 Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by a loss of t

58 n development of Sjogren's syndrome (SjS), a systemic autoimmune disease characterized by a progressi

59 mic lupus erythematosus (SLE) is a prototype systemic autoimmune disease characterized by flares of h

60 s(lpr)) mice develop a rapidly fatal form of systemic autoimmune disease characterized by glomerulone

61 Primary Sjogren syndrome is a systemic autoimmune disease characterized by mouth and e

62 Systemic sclerosis (SSc) is a rare systemic autoimmune disease characterized by skin and or

63 temic lupus erythematosus (SLE) is a chronic systemic autoimmune disease characterized by the product

64 lupus erythematosus (SLE) is a prototypical systemic autoimmune disease characterized by the product

65 tomyositis, and inclusion body myositis) are systemic autoimmune diseases defined by chronic muscle w

66 Patients with juvenile dermatomyositis, a systemic autoimmune disease, displayed a profound skewin

67 Elucidating how a single systemic autoimmune disease engages distinct immune effe

68 B has been implicated in the development of systemic autoimmune disease; however, there has been no

69 s erythematosus is considered a prototype of systemic autoimmune diseases; however, despite considera

70 Systemic autoimmune disease in humans and mice is charac

71 autoantibodies, especially anti-dsDNA, from systemic autoimmune disease in MRL, NZB/W, and motheaten

72 ce of regulatory T cells (Tregs) and a fatal systemic autoimmune disease in scurfy mice.

73 ptor or its ligand (FasL) lead to lupus-like systemic autoimmune diseases in mice and in some humans.

74 y arthritis, as assessed histologically, and systemic autoimmune disease, including glomerulonephriti

75 upations were associated with death from any systemic autoimmune disease, including mining machine op

76 f occupations was associated with death from systemic autoimmune diseases, including several of a pri

77 Ab-dependent and Ab-independent functions in systemic autoimmune diseases, including systemic lupus e

78 Independent systemic autoimmune disease is an uncommon feature.

79 The findings reveal that injury-induced systemic autoimmune disease is exacerbated in the absenc

80 Systemic autoimmune disease is frequently characterized

81 The possible role of B7.2 dysregulation in systemic autoimmune diseases is discussed.

82 ic lupus erythematosus (SLE), the prototypic systemic autoimmune disease, is a debilitating multisyst

83 nts is considered to be the primary cause of systemic autoimmune diseases, like systemic lupus erythe

84 cells maturing to produce autoantibodies in systemic autoimmune diseases, like those in normal immun

85 Systemic sclerosis, or scleroderma, is a systemic autoimmune disease manifest by vascular damage

86 Systemic autoimmune disease manifestations, including ly

87 ment of corneal ulceration in the setting of systemic autoimmune disease may represent progression of

88 Our results suggest that death from systemic autoimmune diseases may be associated with occu

89 both foreign Ag-driven immune responses and systemic autoimmune diseases mediated by B lymphocytes.

90 pothesis that induction of autoantibodies in systemic autoimmune diseases might be triggered by a T c

91 ontrast to oligoclonal expansion observed in systemic autoimmune disease models, insulin-binding B ce

92 1), systemic sclerosis (n = 5,642), or other systemic autoimmune disease (n = 4,270).

93 ccupation was associated with death from any systemic autoimmune disease (OR 1.3 [95% CI 1.2-1.4]), a

94 , but in no sera from 94 patients with other systemic autoimmune diseases (P = 0.016).

95 blic, such as teachers, were associated with systemic autoimmune disease-related death, whereas other

96 epitopes recognized by pathogenic T cells in systemic autoimmune disease remain poorly defined.

97 ty in vivo; the mice rapidly developed fatal systemic autoimmune disease resembling the FoxP3 KO phen

98 Systemic autoimmune diseases result from interactions be

99 oplasmic autoantibody (ANCA) vasculitis is a systemic autoimmune disease resulting in small-vessel in

100 In systemic autoimmune disease, self-tolerance fails, leadi

101 Patients with systemic autoimmune diseases show increased incidence of

102 osaccharide chains (N-glycans), results in a systemic autoimmune disease similar to human systemic lu

103 king Btk an attractive therapeutic target in systemic autoimmune disease such as SLE.

104 H are caused by capillaritis associated with systemic autoimmune diseases such as antineutrophil cyto

105 Systemic autoimmune diseases such as lupus affect multip

106 In systemic autoimmune diseases such as lupus the immune sy

107 e complexes in the serum are associated with systemic autoimmune diseases such as lupus.

108 uced by IFNs during viral. infections and in systemic autoimmune diseases such as systemic lupus eryt

109 ay be of benefit in the treatment of chronic systemic autoimmune diseases such as systemic lupus eryt

110 s strongly implicated in the pathogenesis of systemic autoimmune diseases, such as lupus, and rare mo

111 Autoimmunity to DNA in mouse models for the systemic autoimmune disease systemic lupus erythematosus

112 G production, as well as in the serum of the systemic autoimmune disease systemic lupus erythematosus

113 Type 1 diabetes is a systemic autoimmune disease that can be cured by transpl

114 temic lupus erythematosus (SLE) is a chronic systemic autoimmune disease that disproportionately affe

115 Lupus is a prototypic systemic autoimmune disease that has a significant genet

116 Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that is accompanied by the e

117 erythematosus (SLE) is a heterogenous multi-systemic autoimmune disease that is associated with cons

118 Primary Sjogren's syndrome (SS) is a systemic autoimmune disease that is characterized by ker

119 Lupus-prone mice develop a systemic autoimmune disease that is dependent upon the B

120 ot MHC class I, permitted the development of systemic autoimmune disease that is indistinguishable fr

121 Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that predominantly affects w

122 mic lupus erythematosus (SLE) is a prototype systemic autoimmune disease that results from a break in

123 d autoimmunity (mHgIA) is a T cell-dependent systemic autoimmune disease that shares a number of comm

124 ic inflammatory myopathies (IIMs), which are systemic autoimmune diseases that are characterized by m

125 Tim-1(Deltamucin) mice did not develop frank systemic autoimmune disease unless they were crossed ont

126 negative screening for vasculitis and other systemic autoimmune disease were included.

127 s to DNA and nucleoproteins are expressed in systemic autoimmune diseases, whereas B cells producing

128 stemic lupus erythematosus (SLE) is a common systemic autoimmune disease with complex etiology but st

129 Gluten sensitivity is a systemic autoimmune disease with diverse manifestations.

130 These results suggest that in a systemic autoimmune disease with multiple manifestations

131 Systemic sclerosis is an orphan, systemic autoimmune disease with no FDA-approved treatme

132 Mixed connective tissue disease (MCTD) is a systemic autoimmune disease with significant morbidity a

133 i-dsDNA Id(+) B cells in mice suffering from systemic autoimmune disease with SLE-like features.

134 rtk (TAM) triply knockout (TKO) mice exhibit systemic autoimmune diseases, with characteristics of in