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1 ke; p = 0.020, adjusted p = 0.023 for stroke/systemic embolism).
2 function is a potent predictor of stroke and systemic embolism.
3 The primary endpoint was stroke or systemic embolism.
4 ssociated with increased risk for stroke and systemic embolism.
5 bigatran 110 mg BID in preventing stroke and systemic embolism.
6 icantly increased risk of ischemic stroke or systemic embolism.
7 or the primary outcome of ischemic stroke or systemic embolism.
8 farin for the primary end point of stroke or systemic embolism.
9 to warfarin for the prevention of stroke or systemic embolism.
10 utcome was ischemic or hemorrhagic stroke or systemic embolism.
11 ndpoint of stroke, cardiovascular death, and systemic embolism.
12 including stroke, myocardial infarction, and systemic embolism.
13 f cardiac thrombus formation associated with systemic embolism.
14 dity and mortality due to related stroke and systemic embolism.
15 ctors of stroke/transient ischemic attack or systemic embolism.
16 rms of the risk of having an ischemic stroke/systemic embolism.
17 prior stroke, transient ischemic attack, or systemic embolism.
18 ned as stroke, transient ischemic attack, or systemic embolism.
19 been shown to reduce the risk of stroke and systemic embolism.
20 miodarone-treated patients had a stroke or a systemic embolism (1.58%/year vs. 1.19%/year; adjusted h
22 was associated with a higher rate of stroke/systemic embolism (13.6% vs. 3.2%, p = 0.021, p = 0.047
23 5%; RR, 0.89; 95% CI, 0.82-0.98), and stroke/systemic embolism (2.40% versus 3.13%; RR, 0.77; 95% CI,
24 was significantly associated with stroke or systemic embolism, adjusted hazard ratio 1.98 (1.42-2.78
25 ect of rivaroxaban and warfarin on stroke or systemic embolism among VKA-naive and VKA-experienced pa
27 r of follow-up), the rate of ischemic stroke/systemic embolism and all-cause mortality (per 100 perso
29 The adjusted hazard ratio of ischemic stroke/systemic embolism and all-cause mortality was 0.55 (95%
31 from 0.62 to 0.65 (p = 0.0009) for stroke or systemic embolism and from 0.59 to 0.69 for cardiac deat
33 dysfunction have a higher risk of stroke or systemic embolism and major bleeding but show consistent
34 e clinical cohort, there were similar stroke/systemic embolism and major bleeding rates with dabigatr
35 ith the clinical outcomes of ischemic stroke/systemic embolism and major bleeding using univariate an
36 f apixaban vs warfarin on rates of stroke or systemic embolism and major bleeding were consistent in
37 F trial demonstrated similar risks of stroke/systemic embolism and major/nonmajor clinically relevant
38 outcomes, i.e., stroke (ischemic stroke and systemic embolism) and major bleeding in patients treate
39 mine whether the primary efficacy (stroke or systemic embolism) and safety (major bleeding and nonmaj
40 nial hemorrhage, the rate of ischemic stroke/systemic embolism, and all-cause mortality (per 100 pers
42 therapy (warfarin) for prevention of stroke, systemic embolism, and cardiovascular death in nonvalvul
43 mpared to warfarin for prevention of stroke, systemic embolism, and cardiovascular death in patients
44 composite primary efficacy endpoint (stroke, systemic embolism, and cardiovascular death) is expresse
45 primary efficacy end point included stroke, systemic embolism, and cardiovascular death, and the pri
46 r preventing the combined outcome of stroke, systemic embolism, and cardiovascular death, as well as
47 mposite efficacy end point including stroke, systemic embolism, and cardiovascular/unexplained death,
48 ents of ischemic stroke, hemorrhagic stroke, systemic embolism, and cardiovascular/unexplained death.
49 rior stroke/transient ischemic attack, prior systemic embolism, and congestive heart failure were ass
50 statistics from 0.629 to 0.653 for stroke or systemic embolism, and from 0.591 to 0.731 for cardiac d
51 eeding; apixaban 5 mg B.I.D. reduced stroke, systemic embolism, and mortality as well as major bleedi
52 attack, Caucasian race, hypertension, prior systemic embolism, and New York Heart Association functi
53 Outcomes included the composite of stroke or systemic embolism, any stroke, and major bleeding among,
54 he population attributable risk of stroke or systemic embolism associated with subclinical atrial tac
56 was a significantly increased risk of stroke/systemic embolism at 1 year versus either no diabetes (5
57 The cumulative rate of stroke and stroke/systemic embolism at follow-up were 13.6% and 15.9%, res
58 pixaban compared with warfarin for stroke or systemic embolism, bleeding, and mortality appear simila
59 in statistically similar rates of stroke and systemic embolism, but apixaban had a lower risk of majo
60 was associated with a higher rate of stroke/systemic embolism, but not a higher mortality, at 30 day
62 was a significantly lower risk of stroke and systemic embolism (by 26%) for dabigatran (150 mg BID) c
63 arfarin therapy for the prevention of stroke/systemic embolism/cardiovascular death, there was a sign
64 superior to warfarin in preventing stroke or systemic embolism, caused less bleeding, and resulted in
65 ter than warfarin at prevention of stroke or systemic embolism, causes less bleeding, and results in
66 ive rivaroxaban had a reduction in stroke or systemic embolism compared with those taking warfarin (1
67 as associated with lower rates of stroke and systemic embolism compared with warfarin, without an inc
69 consistently reduced the rate of stroke and systemic embolism, death, and major bleeding compared wi
70 including stroke, non-central nervous system systemic embolism, death, myocardial infarction, and ble
71 terval [CI], 1.16-1.5) but similar stroke or systemic embolism event rates (HR, 1.09; 95% CI, 0.88-1.
72 rences, the long-term incidence of stroke or systemic embolism (hazard ratio [HR]: 1.38; 95% confiden
73 to 8.17; P<0.001) and of ischemic stroke or systemic embolism (hazard ratio, 2.49; 95% CI, 1.28 to 4
74 troke, nonfatal acute myocardial infarction, systemic embolism, heart failure development, or severe
75 these patients had higher rates of stroke or systemic embolism (HR, 1.47; 95% CI, 1.20-1.81) and majo
76 d to be more effective (outcome of stroke or systemic embolism: HR, 0.78; 95% CI, 0.67-0.91; vascular
77 n (HR, 1.53; 95% CI, 1.17-2.01 for stroke or systemic embolism; HR, 1.56; 95% CI, 1.27-1.93 for major
79 associated with the occurrence of stroke and systemic embolism in a large, international atrial fibri
81 uperior to warfarin in preventing stroke and systemic embolism in nonvalvular atrial fibrillation, bu
82 erosis of the aorta is a potential source of systemic embolism in patients undergoing cardiac cathete
83 jor risk factor for perioperative stroke and systemic embolism in patients undergoing cardiac surgery
84 mpared with warfarin (n = 8657) on stroke or systemic embolism in patients with 1 dose-reduction crit
85 is non-inferior for prevention of stroke and systemic embolism in patients with atrial fibrillation a
86 to warfarin for the prevention of stroke and systemic embolism in patients with atrial fibrillation a
87 ulation therapy for the prevention of stroke/systemic embolism in patients with atrial fibrillation.
88 inferior to warfarin in preventing stroke or systemic embolism in patients with atrial fibrillation.
89 ive and safe for the prevention of stroke or systemic embolism in patients with atrial fibrillation.
90 antagonists for the prevention of stroke and systemic embolism in patients with atrial fibrillation.
91 nferior to warfarin in preventing stroke and systemic embolism in patients with atrial fibrillation.
92 all indications except for the prevention of systemic embolism in patients with mechanical heart valv
93 ion of Stroke and Non-Central Nervous System Systemic Embolism in Patients With Non-Valvular Atrial F
94 ion of Stroke and Non-Central Nervous System Systemic Embolism in Patients With Non-Valvular Atrial F
95 ion of Stroke and Non-Central Nervous System Systemic Embolism in Patients With Non-Valvular Atrial F
96 y over warfarin for prevention of stroke and systemic embolism in the 150-mg dose and significantly l
97 dditional factors associated with stroke and systemic embolism included elevated diastolic blood pres
98 ted with reduced risk for ischemic stroke or systemic embolism, intracranial hemorrhage, and all-caus
99 found regarding risk for ischemic stroke or systemic embolism, intracranial hemorrhage, myocardial i
100 the primary endpoint of all-cause stroke or systemic embolism, ischaemic stroke, and all-cause morta
101 rall and cardiovascular mortality, stroke or systemic embolism, ischemic stroke, major and intracrani
106 ed rates of myocardial infarction, stroke or systemic embolism, major bleeding, cause-specific hospit
107 ncidence of myocardial infarction, stroke or systemic embolism, major bleeding, hospitalization, or d
108 fied as "net clinical benefit" (all strokes, systemic embolism, MI, pulmonary embolism, major bleedin
110 an follow-up: 0.99 years) included stroke or systemic embolism, myocardial infarction, major bleeding
111 l effectiveness end point of ischemic stroke/systemic embolism, no significant differences of the NOA
112 During the 30 days postprocedure, stroke or systemic embolism occurred after 16/4624 (0.35%) procedu
115 rence favoring novel oral anticoagulants for systemic embolism (OR, 0.84; 95% CI, 0.72-0.97; P=0.01),
117 e of SCAF in those with a history of stroke, systemic embolism, or transient ischemic attack was 39.4
118 comes were arterial thromboembolism (stroke, systemic embolism, or transient ischemic attack) and maj
119 ly decreased the risk for ischemic stroke or systemic embolism (p = 0.0004 and p = 0.0006, respective
120 statistic from 0.620 to 0.635 for stroke or systemic embolism (p = 0.0226), from 0.592 to 0.711 for
121 ary efficacy analysis was rates of stroke or systemic embolism (per 100 patient-years) by intention t
122 20 +/- 5 months, the rates of death, stroke, systemic embolism, pericardial effusion, and major bleed
124 ing 1.9 years, the annual rates of stroke or systemic embolism ranged from 0.74% in the bottom NT-pro
125 9 years follow-up, annual rates of stroke or systemic embolism ranged from 0.76% in the lowest hs-TnI
126 9-year period, the annual rates of stroke or systemic embolism ranged from 0.87% in the lowest hs-TnT
128 ts who received amiodarone had a stroke or a systemic embolism rate of 1.24%/year versus 1.85%/year (
129 ho did not receive amiodarone, the stroke or systemic embolism rate was 1.29%/year versus 1.57%/year
132 In VKA-experienced patients, stroke and systemic embolism rates were 1.51%, 1.15%, and 1.74% per
135 ated with significantly increased stroke and systemic embolism risk and a lower time in the therapeut
136 erior to well-managed warfarin for stroke or systemic embolism (S/SE) prevention and reduced bleeding
138 l enlargement (LAE) is a predictor of stroke/systemic embolism (SE) in atrial fibrillation (AF) patie
139 irst composite coprimary endpoint of stroke, systemic embolism (SE), or cardiovascular/unexplained de
140 mary efficacy endpoint (composite of stroke, systemic embolism [SE], and cardiovascular/unexplained d
141 strong, independent predictor of stroke and systemic embolism, second only to prior stroke or transi
143 ffective as warfarin in preventing stroke or systemic embolism (the primary end point), because the p
144 The primary efficacy end point was stroke or systemic embolism; the safety end point we studied was m
145 ng the study that report all-cause stroke or systemic embolism, vascular death, myocardial infarction
146 revious stroke or TIA, the rate of stroke or systemic embolism was 1.01 per 100 patient-years of foll
147 revious stroke or TIA, the rate of stroke or systemic embolism was 2.46 per 100 patient-years of foll
149 of rivaroxaban versus warfarin on stroke or systemic embolism was consistent: Rates per 100 patient-
150 (6 randomized controlled trials, n=30,699), systemic embolism was favored with novel oral anticoagul
151 n the ARISTOTLE trial, the rate of stroke or systemic embolism was reduced by apixaban compared with
153 e TTR quartiles, hazard ratios for stroke or systemic embolism were 0.73 (95% confidence interval [CI
158 ninferior to warfarin in reducing stroke and systemic embolism, whether patients received antiplatele
159 absolute reduction in the rate of stroke and systemic embolism with apixaban versus warfarin was 0.77
160 GS: Apixaban significantly reduced stroke or systemic embolism with no evidence of a differential eff
161 . was noninferior to warfarin for stroke and systemic embolism without a difference in major bleeding
162 te 150 mg B.I.D. reduced the rates of stroke/systemic embolism without any difference in major bleedi
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