ライフサイエンスコーパス: systemic infection

1 results in one genetic variant establishing systemic infection.

2 za virus, naive ferrets rapidly succumbed to systemic infection.

3 A) clone usa300 derived directly from murine systemic infectiON.

4 Inoculation into either site causes systemic infection.

5 nthase in an NRAMP1(r) murine model of acute systemic infection.

6 expression of antiviral genes and prevented systemic infection.

7 s essential for MRSA virulence during murine systemic infection.

8 gen in pigs and humans that can cause severe systemic infection.

9 protective or a deleterious function during systemic infection.

10 ed for fungal virulence in a murine model of systemic infection.

11 ministration of BCG has been associated with systemic infection.

12 rough the mediastinal lymph nodes to cause a systemic infection.

13 by the inflammatory mediators that accompany systemic infection.

14 s neoformans into the brain parenchyma after systemic infection.

15 tion and culminating with establishment of a systemic infection.

16 e mechanisms that can help prevent local and systemic infection.

17 ive bacteria or Gram-positive bacilli during systemic infection.

18 ammatory response similar to neutrophilia in systemic infection.

19 ant for dissemination and establishment of a systemic infection.

20 sary for intracellular survival, growth, and systemic infection.

21 and is characterized by severe pneumonia and systemic infection.

22 l inoculation of Listeria markedly decreased systemic infection.

23 hal and some profile 2 strains did not cause systemic infection.

24 l code; or 2) CIED procedure code along with systemic infection.

25 rophylaxis prevented febrile neutropenia and systemic infection.

26 f S. aureus lacking agr in a murine model of systemic infection.

27 restrict the production of flagellin during systemic infection.

28 ulence of P. aeruginosa in a murine model of systemic infection.

29 ride capsule for survival in the host during systemic infection.

30 t the portal of entry necessary to establish systemic infection.

31 erial population and a resulting decrease in systemic infection.

32 nize the intestine but are unaffected during systemic infection.

33 mum opportunity for interventions to prevent systemic infection.

34 itical for controlling GBS dissemination and systemic infection.

35 d/founder viruses responsible for productive systemic infection.

36 es, and spleen, suggesting a role for Hfq in systemic infection.

37 ytes and neutrophils are rapidly depleted by systemic infection.

38 protein that is rapidly cleaved following a systemic infection.

39 equences leading to more extensive local and systemic infection.

40 ong distance through the phloem to establish systemic infection.

41 lation anthrax before the onset of fulminant systemic infection.

42 albicans virulence in two distinct models of systemic infection.

43 g allow us to use the eye as a window to the systemic infection.

44 cess to target cells and tissues, leading to systemic infection.

45 ADAP) in promoting CD8 T cell responses to a systemic infection.

46 1 cell responses provided protection against systemic infection.

47 s; however, it is an extremely rare cause of systemic infection.

48 ation on early pathogen invasion and chronic systemic infection.

49 issue damage in clinical scenarios of severe systemic infection.

50 usly shown to be a major virulence factor in systemic infection.

51 strains lacking a functional RgfA increased systemic infection.

52 significant influence on virus titers during systemic infection.

53 us responsible for chronic mucocutaneous and systemic infections.

54 tified, although it has been associated with systemic infections.

55 r being a primary source of cytokines during systemic infections.

56 intestinal illness and, occasionally, severe systemic infections.

57 eservoir for innate antibiotic resistance in systemic infections.

58 sed to attack cells in immune defense during systemic infections.

59 prevents sustained hyper inflammation during systemic infections.

60 sociated with a diverse array of mucosal and systemic infections.

61 soft tissue infections to potentially lethal systemic infections.

62 virulent and rarely causes life-threatening, systemic infections.

63 amassed predominantly from models of acute, systemic infections.

64 r antigens and are important for immunity to systemic infections.

65 fficult to eradicate, and can lead to lethal systemic infections.

66 teurianus may be an underrecognized agent of systemic infections.

67 le blood environment during life-threatening systemic infections.

68 ulminating in the establishment of efficient systemic infections.

69 ge of infections, including life-threatening systemic infections.

70 lonization, translocation, dissemination and systemic infections.

71 ing that they are not suitable therapies for systemic infections.

72 al blood and the propensity to both skin and systemic infections.

73 lbicans may spread to cause life-threatening systemic infections.

74 e the inflammatory response in patients with systemic infections.

75 rstanding of the role these microbes play in systemic infections.

76 en that causes pneumonia and soft tissue and systemic infections.

77 Indications included systemic infection (18%), pocket infection (32%), lead m

78 sponses play an important role in preventing systemic infection after exposure to the virus.

79 ), promotes acute pulmonary inflammation and systemic infection after lung challenge with S. pneumoni

80 den or cytokine response in a mouse model of systemic infection (after intravenous inoculation) at th

81 lence in mouse models of acute pneumonia and systemic infections, although they grow normally in cult

82 a key virulence factor for the induction of systemic infection and abortion in pregnant animals and

83 slocate across the intestinal tract, causing systemic infection and abortion in pregnant animals.

84 to small amounts of HCV, but do not develop systemic infection and acute liver disease.

85 ort a case of echovirus 18-associated severe systemic infection and acute liver failure in an adult h

86 r the host, where it proliferates and causes systemic infection and death.

87 vere skin infection, not every strain caused systemic infection and death.

88 ocess of cancer metastasis in the context of systemic infection and identify NETs as potential therap

89 roteins are strongly induced in the liver by systemic infection and in the intestine by bacterial col

90 Intrauterine and systemic infection and inflammation cause 30-40% of spon

91 O concentration in the exhaled breath during systemic infection and inflammation, and (ii) encourage

92 During systemic infection and inflammation, immune effector cel

93 bone marrow (BM) injury, transplantation, or systemic infection and inflammation.

94 e a protective role in both gut-centered and systemic infection and inflammation.

95 mutant encoding NS1-ESEV and NS1-138F caused systemic infection and killed mice more efficiently.

96 (-/-) mice with the same vectors resulted in systemic infection and lethal outcome for the majority o

97 nzyme is crucial for host protection against systemic infection and lung challenge by GBS.

98 In vivo mouse systemic infection and neutropenic thigh model experimen

99 PS), but the specific role that CPS plays in systemic infection and particularly abortion in animals

100 cquired through tainted food and may lead to systemic infection and possible death.

101 Additionally, increased GBS systemic infection and preterm births were observed in M

102 serum, and human urine and in vivo in mouse systemic infection and pulmonary challenge models.

103 averse tissue barriers, disseminate to cause systemic infection and reach target organs.

104 Subclinical systemic infection and reinfection with attenuated L. mo

105 ed that HSCs also proliferate in response to systemic infection and replenish effector immune cells.

106 of HAdV in the respiratory tract may precede systemic infection and require early intervention.

107 commandeers patrolling monocytes to mediate systemic infection and seed a persistent reservoir essen

108 ofin is efficacious in a mouse model of MRSA systemic infection and significantly reduces the bacteri

109 monopartite virus that is able to establish systemic infection and silencing of endogenous maize gen

110 UNV C1 determines how quickly mice can clear systemic infection and that this depended on the cellula

111 of 349 amino acids of CP are dispensable for systemic infection and/or virion assembly, which is rare

112 infant gut are more likely to associate with systemic infections and can reach high abundances in ind

113 of this inhibitor for use in vivo to prevent systemic infections and cellular damage, such as that ca

114 reached clinical development for therapy of systemic infections and Clostridium difficile infection

115 syndrome) are associated with cutaneous and systemic infections and early-onset forms of periodontit

116 We review here the most recent findings on systemic infections and inflammation complicated by oral

117 cause of maternal genital tract and neonatal systemic infections and initiates infection by colonizin

118 ing to initial EBV penetration that leads to systemic infection, and (ii) basolateral to apical trans

119 that targets this innate response to prevent systemic infection, and I conclude with an agenda for fu

120 is important for S. pneumoniae to establish systemic infections, and TacL represents a potential tar

121 ), and host related factors (age; coincident systemic infection; and organ dysfunction, especially he

122 e responses in check during establishment of systemic infection are not completely understood.

123 that these coordinators of host responses to systemic infection are required for aPC to provide prote

124 Systemic infections are mainly with Pneumocystis jirovec

125 These studies imply that HIV achieves systemic infection as a consequence of a failure in host

126 nistration of cognate glycolipids and during systemic infection but not following exogenous cytokine

127 fferentially infect SDp2: WSMV-S81 induces a systemic infection, but WSMV-T does not.

128 bility to CD, but also protect the host from systemic infection by a common enteric bacterium.

129 The events driven by systemic infection by bacterial pathogens on the T cell

130 Sts enzymes leads to profound resistance to systemic infection by C. albicans, such that greater tha

131 at Sts(-/-) mice are profoundly resistant to systemic infection by Candida albicans, with resistance

132 for inhibition of neutrophil recruitment and systemic infection by hypervirulent GAS.

133 MET-1 may attenuate systemic infection by preserving tight junctions, thereb

134 (LysMcre) mice were also more susceptible to systemic infection by S Typhimurium than wild-type mice.

135 C57BL/6J mice are extremely susceptible to systemic infection by Salmonella Typhimurium because of

136 o have no effect on replication, movement or systemic infection by the challenge virus.

137 Systemic infection by the pathogenic yeast Candida albic

138 nhibition of anorexia prevented invasion and systemic infection by wild-type S.

139 2 with WSMV-T and/or WSMV-S81 did not affect systemic infection by WSMV-S81, suggesting that WSMV-T d

140 al antigens and conferred protection against systemic infections by E. coli and Salmonella by directl

141 ling and protected mice against local and/or systemic infections by Streptococcus pyogenes, Streptoco

142 During systemic infection C. albicans is disseminated via the c

143 own of the blood-brain barrier, showing that systemic infection can alter the pathogenesis of MS-like

144 The term given to the severe pneumonia and systemic infection caused by Legionella bacteria is Legi

145 ntimicrobial treatment for typhoid, a severe systemic infection caused by the bacterium Salmonella en

146 hat dietary Mn levels dictate the outcome of systemic infections caused by Staphylococcus aureus, a l

147 Although Listeria monocytogenes can induce systemic infection causing spontaneous abortion, septice

148 thereby preventing acquisition and averting systemic infection, CD4 T-cell depletion and pathologies

149 Streptococcus iniae causes systemic infection characterized by meningitis and sepsi

150 ial results and experimental models, include systemic infections, deleterious metabolic activities, e

151 f plant xylem tissues and the development of systemic infections, deletion of the two biofilm-promoti

152 k for complications and early mortality from systemic infection despite device extraction and appropr

153 Bacterial pathogens causing systemic infections disseminate from the initial infecti

154 also known as San Joaquin Valley fever, is a systemic infection endemic to parts of the southwestern

155 markedly reduced for their ability to cause systemic infections, exhibit decreased beta-hemolysin/cy

156 ntical, co-housed Drosophila given identical systemic infections experience different outcomes, with

157 9-day-old (P9), rat pups are susceptible to systemic infection following gastrointestinal colonizati

158 ococcal infection and is required for lethal systemic infection following S. pneumoniae lung challeng

159 tions, with continued virion assembly and/or systemic infection found after extensive deletions are m

160 In this study, we demonstrate that systemic infection fundamentally modifies the traffickin

161 preeclampsia/eclampsia and postpartum acute systemic infection had the highest risk of VTE during th

162 suggest that adaptation during the course of systemic infection has implications beyond the level of

163 rus (CCoV) variants that are associated with systemic infections have been reported in the European U

164 In multivariable analysis, systemic infection (hazard ratio [HR], 3.52; 95% CI, 1.9

165 is a common, life-threatening consequence of systemic infection; however, the underlying mechanisms t

166 Conversely, in systemic infection, hyperinflammation associated with M1

167 Reasons for isolated enterectomy included systemic infection in 11, gastrointestinal bleeding in 1

168 can inhibit neutrophil recruitment and cause systemic infection in a mouse model of skin infection.

169 he Hrp pathogenicity island, is required for systemic infection in apple.

170 d to be strong and long-lasting, pointing to systemic infection in humans.

171 fer of B1a cells was protective during acute systemic infection in IL-10-deficient hosts.

172 urvival of A. baumannii in a lethal model of systemic infection in immunocompetent mice.

173 e that the FoMV infectious clone establishes systemic infection in maize inbred lines, sorghum (Sorgh

174 During early systemic infection in mice with serotype 1, large-colony

175 capsule and magA contribute to virulence of systemic infection in mice; however, little is known abo

176 for efficient TVCV cell-to-cell movement and systemic infection in Nicotiana benthamiana and Arabidop

177 major fungal pathogen that frequently causes systemic infection in patients with compromised immunity

178 to inhibition of neutrophil recruitment and systemic infection in subcutaneous infection of mice by

179 Moreover, simulation of a minor systemic infection in tumor-bearing, but not control, mi

180 ported by in vivo data from a mouse model of systemic infection in which NKKY101 cells led to higher

181 mmunodeficiency state and heightened risk of systemic infections in advanced liver disease.

182 sae and skin, but it causes life-threatening systemic infections in hospital settings in the face of

183 en associated with superficial, visceral, or systemic infections in humans, other mammals, or cold-bl

184 dimorphic fungus capable of causing lung and systemic infections in immunocompetent animal hosts.

185 ultative intracellular bacterium that causes systemic infections in immunocompromised hosts.

186 Systemic infections in Melody valve-implanted patients w

187 Thus, multimodality imaging of experimental systemic infections in real time indicates complex dynam

188 ithelium and biofilm formation, while during systemic infection, increased capsule is required to eva

189 tion on erythroid development and found that systemic infection induced anemia, splenomegaly, elevate

190 Systemic infection induces conserved physiological respo

191 Thus, ECs catalyze the detection of systemic infection into demand-adapted granulopoiesis.

192 Systemic infection is characterized by septicemia, toxem

193 eling how mucosal exposure of HIV results in systemic infection is critical for the development of ef

194 In a SYTA knockdown line, CaLCuV systemic infection is delayed, and cell-to-cell spread o

195 immunodeficiency virus type 1 transmission, systemic infection is established by one or only a few v

196 ion of HIV-1, like many pathogens that cause systemic infection, is structured and differentiated wit

197 onellae in that it causes a life-threatening systemic infection known as typhoid fever.

198 ontagious viruses infecting humans, causes a systemic infection leading to fever, immune suppression,

199 ortedly, are the bacterial pathogens causing systemic infections like gastroenteritis and typhoid fev

200 During murine systemic infection, LipA suppresses pro-inflammatory mac

201 antation within 12 weeks of baseline; active systemic infection; malignancy within the last 5 years;

202 In this study, we evaluated a systemic infection model of C. tropicalis, a clinically

203 Challenge of HlaH35L-immunized mice using a systemic infection model resulted in a limited, but stat

204 Here we established a novel zebrafish larvae systemic infection model showing that Pg rapidly adheres

205 In this article, we show in a systemic infection model that the major receptor for C5a

206 Compounds were screened in a murine systemic infection model to rapidly identify compounds w

207 A murine systemic infection model was used as an oral efficacy sc

208 timal growth in serum, virulence in a murine systemic infection model, and antifungal drug tolerance

209 bliniensis in the Galleria mellonella insect systemic infection model.

210 opment and survival of memory CD8 T cells in systemic infection models, we hypothesized that TSLP spa

211 virulence of this organism in orogastric or systemic infection models.

212 de data supporting the in vivo efficacy in a systemic infection murine model setup with a drug-resist

213 Systemic infection occurred across inflamed but not norm

214 nderwent extraction of 1,838 leads; local or systemic infection occurred in 480 patients.

215 d the p33 or the p13 gene was sufficient for systemic infection of calamondin plants.

216 r the p33 or the p18 gene was sufficient for systemic infection of grapefruit trees and the p33 or th

217 d reduced responsiveness to IFN-gamma during systemic infection of IFN-alphabeta-responsive mice.

218 nterica serovar Typhimurium causes a natural systemic infection of mice that models acute and chronic

219 It also is required to prevent systemic infection of mice with enteric bacteria.

220 We show that systemic infection of mice with Escherichia coli, common

221 08 and ytfE promote Salmonella growth during systemic infection of mice.

222 nicity island (SPI-2), which is required for systemic infection of Salmonella.

223 SMV-T isolates were collectively involved in systemic infection of SDp2.

224 other viruses and that are not required for systemic infection of some species of citrus, which allo

225 ed as an important virulence determinant for systemic infection of Streptococcus iniae.

226 essential step in establishing the efficient systemic infection of the entire plant.

227 Thus, these three genes are required for systemic infection of the full host range of CTV, but di

228 ssues, confirmed that TuMV could establish a systemic infection of the plant by going through xylem v

229 , p18, and p13 genes that are expendable for systemic infection of the two laboratory hosts, Citrus m

230 We evaluated the system with experimental systemic infections of severe combined immunodeficiency

231 ever, this fungus can also cause mucosal and systemic infections once immune function is compromised.

232 ruit the target cells necessary to establish systemic infection, opens a promising new avenue for the

233 g and cognitive function often occurs during systemic infection or inflammation.

234 their deletion causing no obvious effects on systemic infection or virion assembly.

235 on is required for high-level bacteremia and systemic infection, partly by disrupting lung epithelium

236 infection promotes T(H)17 immunity, whereas systemic infection promotes T(H)1 immunity.

237 After hospitalization, remote-site invasive systemic infection related to DFU (DFU-ISI) may occur.

238 Optimal protection following respiratory or systemic infection required a mixture of Abs that target

239 may occur, ranging from mucosal to invasive systemic infections resulting in microbe-mediated and/or

240 During systemic infection, Salmonella avoids NLRC4 inflammasome

241 etween 1 and 10 viruses were responsible for systemic infection, similar to humans infected by sexual

242 Despite establishing a systemic infection, SNV differentially activated host re

243 nthracis exhibits a rapid growth rate during systemic infection, suggesting that the bacterium expres

244 (W83) infection of Drosophila resulted in a systemic infection that killed in a dose-dependent manne

245 e spirochete Leptospira interrogans causes a systemic infection that provokes a febrile illness.

246 biotic-resistant bacteria (ARB) are prone to systemic infections that are difficult to treat.

247 erficial mucosal infections to disseminated, systemic infections that are often lifethreatening.

248 Listeria monocytogenes Within a few hours of systemic infection, the massive proliferation of L. mono

249 from superficial mucosal to life-threatening systemic infections, the latter particularly in patients

250 function for the gut microbiota in combating systemic infection through the induction of protective I

251 thymic homeostasis can constantly adjust to systemic infection to ensure that naive T cell output is

252 We used a murine model of systemic infection to test the virulence of a PhoQ-defic

253 s is by shifting from a virulent lifestyle, (systemic infection), to a dormant carrier state.

254 ella including Salmonella Typhi which causes systemic infection, typhoid, in humans.

255 ll-depleted mice also developed disseminated systemic infection, unlike control infected mice.

256 Using an in vivo model of systemic infection, we demonstrated that the ability of

257 After systemic infection, we found that >95% of memory CD8 T c

258 mouse models of intestinal colonization and systemic infection, we identified eight transcription re

259 ot involved in T(H)1 immune responses during systemic infection, whereas the TLR2/TLR6 receptor compl

260 ion to previously reported associations with systemic infection, which are reviewed herein, Lyme dise

261 Systemic infections, which frequently precede relapses i

262 itis is a lethal disease of felids caused by systemic infection with a feline coronavirus.

263 eficiency or inactivation protects mice from systemic infection with a lethal dose of C. albicans, an

264 By contrast, systemic infection with a murine cytomegalovirus (MCMV)

265 or acute decompensated heart failure, severe systemic infection with at least one risk factor for ven

266 Sirpalpha(-)/(-) mice succumbed to systemic infection with attenuated Salmonella, possessin

267 ndancy of CD4(+) T cells for defense against systemic infection with C. albicans and have important i

268 mice, dectin-1 is essential for controlling systemic infection with C. albicans but appears to be re

269 Using a mouse model of systemic infection with C. albicans, we identified the S

270 s more effective than amphotericin B against systemic infection with C. neoformans.

271 ce was observed as host sensitivity to early systemic infection with Candida albicans and T cell-medi

272 on of TNF-alpha and IL-6 and lethality after systemic infection with E. faecalis despite normal bacte

273 However, during systemic infection with either pathogen, MPYS deficiency

274 The strong age dependency of neonatal systemic infection with Escherichia coli K1 can be repli

275 icrobial protein, is critical for control of systemic infection with Escherichia coli; however, its r

276 that these memory responses protect against systemic infection with GAS.

277 Systemic infection with HSV-1, a persistent latent virus

278 n preventing dissemination of VACV following systemic infection with large doses of virus, it is whol

279 Indeed, following systemic infection with Listeria monocytogenes, germ-fre

280 se cells with memory T cells generated after systemic infection with lymphocytic choriomeningitis vir

281 d profile 2 were more likely to cause lethal systemic infection with more severe indicators of virule

282 Systemic infection with murine cytomegalovirus elicited

283 This study investigated the effect of systemic infection with murine cytomegalovirus on the di

284 25 million people annually and results from systemic infection with Salmonella enterica serovar Typh

285 However, mutant mice rapidly succumb to systemic infection with Salmonella Typhimurium, a pathog

286 erse settings of glycolipid immunization and systemic infection with Streptococcus pneumoniae.

287 emale B10.T(6R) mice are highly resistant to systemic infection with the KIM5 strain of Yersinia pest

288 icient in alpha(X)beta(2) were more prone to systemic infection with the LD(5)(0) fungal inoculum dec

289 deficiency rendered mice more susceptible to systemic infection with the pathogenic bacterium group B

290 Unexpectedly, we found that systemic infection with the protozoan Toxoplasma gondii

291 ne is required for effective host defense to systemic infection with this organism.

292 classic Whipple's disease (CWD), the chronic systemic infection with Tropheryma whipplei, immune reco

293 xoma virus is nonpathogenic in mice, whereas systemic infection with vaccinia virus can be lethal eve

294 Systemic infection with virulent L. monocytogenes induce

295 play important roles in host defense against systemic infections with extracellular bacteria and fung

296 Systemic infections with Gram-negative bacteria are char

297 Together, these data show that systemic infections with lethal and sublethal amounts of

298 Systemic infections with multidrug-resistant enterococci

299 control of gastrointestinal invasion during systemic infection, with dectin-1 deficiency associating

300 ebrates, wild-type flies contain C. glabrata systemic infections yet are unable to kill the injected