ライフサイエンスコーパス: tackle

1 se of subtle effects that are challenging to tackle.

2 e tree have made no-limit poker difficult to tackle.

3 yl-hydroxytoluene (BHT) at 20 and 800ppm was tackled.

4 ever, a number of research frontiers must be tackled.

5 ture of heart failure that still needs to be tackled.

6 cent years, some key challenges remain to be tackled.

7 This paper presents a method to tackle a key step in the RNA 3D structure prediction pro

8 iques and can offer fresh insights on how to tackle a range of challenges facing the natural world.

9 earchers can then extend the basic method to tackle a range of existing questions in ecology and expl

10 single cells and opens new opportunities to tackle a range of fundamental biology questions includin

11 s of qubits, such simulators will be able to tackle a wider range of problems, such as materials desi

12 dentify the correct particle size for use in tackling a particular separation problem.

13 Tackling aberrations in glucose-stimulated insulin relea

14 n strategies may be required to successfully tackle AD.

15 a hierarchical structured silicon anode that tackles all three of these problems.

16 Since the issue has been tackled almost exclusively by macroscopic techniques so

17 This important public issue should be tackled, and it should be addressed in early infancy.

18 New antibacterials are needed to tackle antibiotic-resistant bacteria.

19 By tackling antifungal drug resistance as an evolutionary p

20 their levels may provide a new approach for tackling apoptosis and myocardial infarction.

21 l of 2D nanomaterials and how they have been tackled are discussed, and include nanosheet aggregation

22 Additionally, the screening process is tackled as a deterministic problem.

23 genome-wide analyses, but current approaches tackle average methylation within a locus and are often

24 technology, several challenges remain to be tackled before its successful applications for human pat

25 community of the urgency to comprehensively tackle both HBV and HCV are still needed.

26 y methanol, offers a powerful alternative to tackle both issues, that is, global climate change and f

27 In order to tackle both of these challenges, we propose a novel popu

28 ss-cutting and flexible capacities needed to tackle both the burden of existing diseases and EID thre

29 Here, we introduce MS2LDA+ that tackles both above-mentioned problems.

30 ate a cost-efficient and fast technique that tackles both issues simultaneously.

31 ise of identifying non-intuitive targets for tackling both acquired and intrinsic resistance in this

32 d-brain barrier, could be a precious tool to tackle brain disorders.

33 Global climate change effects are hard to tackle but recent studies show that some coral species c

34 rger systems and/or longer time-scales to be tackled, but attempts to machine-learn this functional h

35 newly found in nature or those difficult to tackle by conventional means.

36 This is usually tackled by implementing unattractive cumbersome designs.

37 The sensitivity issue may be tackled by increasing the number of exchanging protons i

38 he problem of GO (gene ontology) sparsity is tackled by introducing the homolog knowledge as independ

39 igh demand for faster computers is currently tackled by traditional methods such as size scaling (for

40 institutions, and agencies can integrate to tackle challenges that can be as complex as the resource

41 lying every Mendelian phenotype will require tackling challenges such as worldwide ascertainment and

42 anagement is ideal for individuals who enjoy tackling challenges that have both technical and busines

43 vel and conceptually distinctive strategy to tackle challenging asymmetric gold catalysis, which to d

44 r designed enzymes with radical cofactors to tackle challenging chemistry.

45 mpling and offers an independent approach to tackle challenging questions related to past population

46 ty of the electron correlation permits us to tackle chemical systems that, due to their size, would n

47 Nutrition policies to tackle child obesity need to promote healthy growth and

48 missions from anthropogenic sources and thus tackle climate change.

49 Tackling climate change is an opportunity to dramaticall

50 led by forward-selection-based procedures to tackle complex covariance structures of gene-gene intera

51 ty in the optical system can be exploited to tackle complex optimization problems directly, on the ha

52 ly recognized that our collective ability to tackle complex problems will require the development of

53 and proof of the power of such approaches in tackling complex problems in nervous system biology.

54 Current models tackle consumer location choices at an aggregate level a

55 ed many advances, but the field continues to tackle controversies and challenging problems, revisit o

56 ctices, and propose innovative approaches to tackle CRVS challenges.

57 ew functional proteins from the ground up to tackle current challenges in biomedicine and nanotechnol

58 oceans, has led to many initiatives aimed at tackling destructive fishing practices and promoting the

59 There are two central challenges to be tackled: developing objective measures that capture the

60 ogical issues must be carefully addressed to tackle difficult phylogenetic questions and pave the roa

61 Macrocycles are ideal in efforts to tackle "difficult" targets, but our understanding of wha

62 pharmacological strategies hold promise for tackling disease-related networks.

63 are needs or guide preventative measures for tackling diseases of older age.

64 s sHSPs attractive for investigating ways to tackle disorders of protein aggregation.

65 y and health system intervention designed to tackle disrespect and abuse by changing the norms and st

66 ss as we scale toward real-world complexity, tackling domains for which ready-made formal models are

67 d to develop much needed new therapeutics to tackle eating disorders and obesity.

68 ised to bring these new tools to effectively tackle EB.

69 t challenges of the coming decades cannot be tackled effectively without reliable data for births, de

70 ing systems with algorithmic developments to tackle emerging 'big data' problems in biomedical resear

71 and coordinated global response is needed to tackle emerging viruses that can cause fatal respiratory

72 of combined immunotherapy strategies able to tackle established tumors.

73 Here, Ryan et al. tackle first-order defocus, an artefact of a non-uniform

74 udy of proteins, but many challenges must be tackled for it to fulfill its promise.

75 ave allowed the study of oxidative stress to tackle fundamental questions and have provided several c

76 g, thus providing an alternative approach to tackle fundamental questions on circuit remodeling.

77 resources, we encourage animal ecologists to tackle global ecological and evolutionary questions with

78 also show that the method can satisfactorily tackle great challenging problems faced by the density f

79 New therapeutics to tackle HIV-1 infection should aim to combine rapid innat

80 ines the key components of WHO's strategy to tackle HIVDR and the role the organization takes in lead

81 trate that quantum computers will be able to tackle important problems in chemistry without requiring

82 In this study, these issues were tackled in an integrated manner using a multi-stage stra

83 RGC neurodegeneration and optic atrophy are tackled in an integrated way, considering all relevant p

84 ail the many challenges that will need to be tackled in the pursuit of efficiency.

85 what kinds of new scientific problems can be tackled in the short term, and what long-term directions

86 icellular organisms, they can be effectively tackled in theDrosophilamodel, by a combination of genet

87 s, larger and more complex genomes are being tackled, including polyploid plant genomes.

88 wealth of data, computers are being asked to tackle increasingly complex learning tasks, often with a

89 ldren in national ophthalmic public policies tackling inequalities.

90 ies to reduce inequalities in adult BMI that tackle inequality with respect to both childhood and adu

91 Innovative approaches to tackle infections are urgently needed.

92 ture and convenient data dumps, allows it to tackle its rich disease annotation landscape, and facili

93 y estimating the scale of WEEE can assist in tackling its associated issues.

94 s, which might offer an unique advantages to tackle key energy, medical and environmental issues.

95 f the Ising machine, offering a new path for tackling larger and more complex instances.

96 Our review provides a framework to tackle lingering questions in DUB biology.

97 on ten themes: strengthen CKD surveillance; tackle major risk factors for CKD; reduce acute kidney i

98 The long-term goal of the global effort to tackle malaria is national and regional elimination and

99 rioritized internationally as a key means of tackling malnutrition; however, there is a lack of clear

100 roaches have opened up new possibilities for tackling many fundamental questions about this important

101 delling approach has broad applicability for tackling many key ecological questions for which we have

102 Our result suggests a new way to tackle Markovian decoherence in a delayed manner, applic

103 characterized in quantum simulators able to tackle medium-to-large-size systems.

104 CSF1R activation as a promising approach to tackle microglial activation and the progression of Alzh

105 devices the approach offers opportunities to tackle much needed improvements in the performance of en

106 r immense potential as therapeutic agents to tackle multidrug resistant bacterial infections.

107 point for the development of novel drugs to tackle multidrug-resistant tuberculosis.

108 ould inform the design of new strategies for tackling multidrug resistance.

109 In that implementation, a novel approach to tackle multiple testing from a Bayesian perspective thro

110 hening and test price reductions, as well as tackling multiple programmatic and funding challenges.

111 dietary elements other than confectionery to tackle obesity.

112 ation, systematic measurement, and effective tackling of coverage and configuration challenges to imp

113 ative tactics, and additional approaches for tackling other global issues, even those beyond public h

114 Early interventions to tackle parental mental disorders may be beneficial to bo

115 lease and IL-1beta maturation is crucial for tackling pathological conditions, including infections,

116 , the parasite is equipped with machinery to tackle perturbations in the secretory pathway, like the

117 a previously collected by genetic studies to tackle phenotypic heterogeneity in MDD can successfully

118 Thus, it is important to tackle pollen-related food allergies from different angl

119 fragment-based drug discovery approaches to tackle PPIs are often stymied by difficulties in the pro

120 Tackling PPIs, particularly by stabilizing clinically fa

121 We present a strategy for tackling preferred specimen orientation in single-partic

122 ory settings, but also allows researchers to tackle real-world problems, such as multilingualism, the

123 mentals of clinical trial design, this paper tackles related controversial issues: noninferiority tri

124 , two cohorts of students have participated, tackling research topics including vaccine design, enzym

125 This warrants dual action in tackling rising BMI and identifying favorable determinan

126 This paper tackles several statistical controversies that are commo

127 Both targets are relevant for tackling several types of addiction (most notably nicoti

128 Tackling severe acute malnutrition (SAM) is a global hea

129 changing epidemiology whilst simultaneously tackling significant pockets of sustained or increasing

130 implies a shift in the way data analysis is tackled, since the probability of interfering compounds

131 ite the existing country-specific strategies tackling social inequalities in visual health in adults,

132 e, improving situational judgment tests, and tackling socially desirable responding are discussed.

133 clarifications regarding our perspective and tackle some common misperceptions, including, for exampl

134 y promote tau hyperphosphorylation and if so tackle some of its underlying mechanisms.

135 19 gene expression group published 9 papers, tackling some timely and important problems and question

136 r enzymatic potencies while at the same time tackling successfully an uncovered selectivity issue wit

137 ctions to the use of the Wolfram Language to tackle such problems in bioinformatics.

138 One approach for tackling such a daunting scientific endeavour for comple

139 mes may represent a therapeutic strategy for tackling such diseases.

140 n section, we employed gene synonym lists to tackle term difference problems.

141 To tackle the 2-variant case, we exploit Fisher's angular t

142 Herein, we tackle the biggest controversy in the UPR literature: th

143 d work together in a more cohesive manner to tackle the burden of hepatitis C in sub-Saharan Africa.

144 However, realizing single-DNA arrays must tackle the challenge of capturing structurally highly dy

145 ssion (AIE) feature offer a timely remedy to tackle the challenge.

146 d Comprehensive lncRNA detection pipeline to tackle the challenge.

147 Therefore, in this work, we have begun to tackle the challenges of EM by introducing additional st

148 ff-Kishner (WK) reduction, to simultaneously tackle the challenges regarding step economy and selecti

149 d both experimentalists and theoreticians to tackle the challenging task of understanding how the int

150 help generate new intervention strategies to tackle the clinical challenges and to alleviate the pers

151 tionships between system variables, can help tackle the complexities involved in creating and analyzi

152 genetics and common molecular approaches to tackle the complexity associated with lipid biosynthesis

153 To tackle the computation problem, they have turned to part

154 aprotic lithium-oxygen batteries and help to tackle the critical issues confronted.

155 This system has the potential to tackle the disadvantages inherit of conventional pharmac

156 ed health policies need to be implemented to tackle the diverse challenges faced by local health-care

157 parasite lifecycle are urgently required to tackle the emerging problem of resistance with current d

158 g how these systems interact is necessary to tackle the global burden of hypertension.

159 concrete insights, tools, and strategies to tackle the health inequities that affect migrants and ot

160 We believe that action is needed to tackle the high levels and continuing growth in sales of

161 To tackle the hypothesis that alternative neural pathways c

162 d on urban mining needs to be established to tackle the increasing supply risk of critical metals suc

163 itory perception will aid us in the quest to tackle the increasingly important problem of hearing los

164 engineering could be a promising strategy to tackle the intrinsic problems of lithium metal anodes.

165 Herein we develop a joint approach to tackle the issue of distinguishing between nanoparticle

166 ol developed for jMRUI, namely jMRUI2XML, to tackle the latter limitation.

167 fication tools, the field is now prepared to tackle the long-standing question of the evolutionary ba

168 nced DNA damage and chemotherapy in order to tackle the major hurdle of increased cancer cell growth

169 ered a paradigm of the ground work needed to tackle the molecular basis of all the protein-aggregatio

170 ovative analytical approach was developed to tackle the most common adulterations and quality deviati

171 Seeking economic growth and job creation to tackle the nation's extreme poverty, the Nicaraguan gove

172 As an application, we tackle the outstanding problem of spatially and spectral

173 To tackle the problem of complex interaction of multiple QT

174 Here, we tackle the problem of extracting network-level informati

175 the beam energy further, it is necessary to tackle the problem of the depletion of laser energy, by

176 Here, we tackle the problem using athermal granular particles.

177 These results open new prospects to tackle the proteasome functional mechanisms.

178 es emphasises the need for new approaches to tackle the public health challenge of sexually transmitt

179 with novel mechanisms of action in order to tackle the scourge of drug-resistant tuberculosis.

180 this Perspective, we present approaches that tackle the stimulating problem of efficiency while answe

181 To tackle the stringent significance cutoff of GWAS, we uti

182 rvention; and (3) working collaboratively to tackle the structures, institutions, and processes that

183 tiatives now provide unique opportunities to tackle the tuberculosis epidemic through collaborative p

184 ed; at the same time, policies that can help tackle the upstream determinants of oral health disparit

185 eds appropriate sustainable interventions to tackle the upstream drivers of HIV risk and successfully

186 to proceed with research and cooperation to tackle the vast number of PFASs on the market and in the

187 such as olive oil, could be one solution to tackle the worldwide epidemic of vitamin D deficiency an

188 RSG-Argentina tackled the challenge of organizing a two-day symposium,

189 Previous research has tackled the first two issues, but the last is still most

190 However, none of the studies tackled the problem of whether the Cry-dependent magneto

191 Over a decade of studies have tackled the question of how FtsK/SpoIIIE translocases es

192 We tackled the question of how the strain and biochemical m

193 and dental hygiene would not be needed if we tackled the single cause--sugars.

194 e form of its N-hydroxy prodrug-successfully tackled the two key limitations of currently used NA inh

195 omparison with current methods, our approach tackles the challenges posed by transition zones and suc

196 This study firstly tackles the direct measurement of the tensile properties

197 sent CCBuilder, a web-based application that tackles the problem for a defined but large class of pro

198 The method tackles the problem with a different strategy.

199 and hence, the potential of this approach in tackling the challenges of high cancer-induced mortality

200 isting predictors are far from effective for tackling the challenges of multi-label proteins.

201 s outline a wider public health approach for tackling the disease.

202 om efforts to reduce mortality to a focus on tackling the downstream consequence of survival: post-in

203 ential for delivering equitable outcomes and tackling the growing burden of cancer in all resource se

204 We group these into three main categories; tackling the heterogeneity in phenotype that is found wi

205 alternatives to traditional antibiotics for tackling the issue of bacterial multidrug resistance.

206 nual wild poliovirus (WPV) cases since 1988, tackling the last 1% has proven difficult.

207 view the multi-faceted duties of sirtuins in tackling the metabolic hurdles in cancer.

208 akers should consider interventions aimed at tackling the obesogenic built environment.

209 We commend Menninghaus et al. for tackling the role of negative emotions in art reception.

210 Identifying and tackling the social determinants of infectious diseases

211 cing the survival of leukemic cells and also tackling their chemoresistance.

212 issues, we propose to visualize biobricks to tackle them.

213 To tackle these analytical challenges, we developed a mass

214 , and how this combined approach can help to tackle these challenges (Section 1), we provide examples

215 zers (SLOT) are proposed and demonstrated to tackle these challenges concurrently.

216 To tackle these challenges, this study presents a novel cro

217 Network neuroscience proposes to tackle these enduring challenges.

218 A useful model to tackle these issues is the Drosophila suzukii - Wolbachi

219 thy nations, increased efforts are needed to tackle these major risk factors, particularly smoking an

220 To tackle these problems, we have sequenced transcriptomes

221 To tackle these problems, we present an interpretable and e

222 t of electronic tongues as a new strategy to tackle these problems.

223 ngle-cell genomics is opening up new ways to tackle these questions by combining the comprehensive na

224 To tackle these questions, we carried out a series of behav

225 We present protocols and software to tackle these steps, focusing on the imaging-based study

226 The Human Genome Variation Archive (HGVA) tackles these challenges and facilitates access to genom

227 This review tackles these questions.

228 We review how contemporary approaches are tackling these challenges and will ultimately serve as a

229 Here, we describe a new approach to tackling these dangerous side effects.

230 l molecules represents an ideal strategy for tackling these types of cancers.

231 Here, we try to tackle this challenge by introducing the concept of a re

232 To tackle this challenge in a systematic and unbiased manne

233 ain-optical coherence tomography (SD-OCT) to tackle this challenge, in which PAOM measured the sO2 an

234 To tackle this challenge, speakers described methods for as

235 form a molecular complex with a metal ion to tackle this challenge.

236 mental health comorbidities are warranted to tackle this considerable burden.

237 Here, we present a versatile methodology to tackle this design issue by exploiting the ethyne-bridge

238 To tackle this difficulty, we developed a single solid-phas

239 To tackle this disease burden in migrants, a comprehensive

240 o new areas of interdisciplinary research to tackle this important public health epidemic.

241 ing our healthcare and research resources to tackle this important public health issue.

242 e of Developmental Cell, Uygur et al. (2016) tackle this issue in the context of neural tube patterni

243 A strategy to tackle this issue is to observe particular features of h

244 To tackle this issue, 172 patients with an infarct initiall

245 To tackle this issue, we developed a novel computational fr

246 To tackle this issue, we used an inverse optimal control ap

247 of experimental approaches which attempt to tackle this issue.

248 s, using Lyz2-Cre x Gata6(flox/flox) mice to tackle this issue.

249 vironment may provide a powerful platform to tackle this issue.

250 Here, we tackle this mutual incompatibility by recognizing that t

251 -child health researchers who were poised to tackle this new public health challenge; and (3) the hig

252 mmunities to make a more concerted effort to tackle this problem and propose potential approaches bot

253 Here we tackle this problem by carrying out the first genome-wid

254 We tackle this problem by developing an algorithm to enumer

255 We thought to tackle this problem by taking a systems biology approach

256 We tackle this problem by using hydrodynamic simulations of

257 Here we review studies that tackle this problem from a diverse set of approaches, fr

258 s, this study elaborates on Leonard turns to tackle this problem in a general manner.

259 any clustering methods have been employed to tackle this problem in a purely data-driven manner.

260 One approach to tackle this problem is to identify compounds that target

261 One way to tackle this problem is to treat them as absent.

262 To tackle this problem, a group combined P-value method (GC

263 To tackle this problem, the fusions of fluorescent proteins

264 To tackle this problem, we devised a protein engineering st

265 le trial-based evidence for interventions to tackle this problem.

266 ng from several research domains can help to tackle this problem.

267 ght and emphasise the need for investment to tackle this public health issue.

268 Here, we tackle this question by comparing an enzyme with its hea

269 recent landmark article in Nature begins to tackle this question by using modern genetic approaches

270 inally, we discuss future studies that might tackle this question further.

271 To tackle this question, we have analyzed the contribution

272 To tackle this question, we used solid-state NMR strategies

273 To tackle this question, we used the Drosophila model in wh

274 arnesoid X receptor), as our model system to tackle this question.

275 We tackled this issue using two decadally (13) C-labeled so

276 We tackled this problem by computational modeling.

277 A study by Bendesky et al. (2017) tackles this challenge by dissecting the genetic archite

278 A new study tackles this important issue using bioinformatics approa

279 Zld tackles this nucleosome barrier through local depletion

280 Our method tackles this problem for large networks while providing

281 cientists to develop creative strategies for tackling this challenge.

282 Previous work tackling this problem has relied on the original circuit

283 lution 2D-LC combined with active modulation tackles three of the main challenges encountered in 2D-L

284 eaction is one of the issues that need to be tackled to allow the widespread use of hydrogen as an en

285 edge and identify challenges that need to be tackled to resolve the impasse in understanding extreme

286 s wonderful to discover something new and to tackle tough puzzles.

287 Microarray analysis is used to tackle transplant-related problems as diverse as diagnos

288 made from oxygen-generating biomaterials to tackle transport limitations deep within the engineered

289 t targeting RNF8 is an appealing strategy to tackle tumor aggressiveness and treatment resistance.

290 ework for design of combination therapy that tackles tumor heterogeneity while satisfying toxicity co

291 gital holographic imaging techniques need to tackle two major challenges: phase recovery and spatial

292 Tackling unconscious bias is a major challenge for journ

293 These features allow chemists to tackle unexploited challenges in their work, with the ul

294 Cell growth kinetics is tackled using the continuous logistic equation modified

295 ns with socioeconomic factors show a need to tackle vaccine confidence, whereas strengthening correla

296 enges with such research include the need to tackle variability in quality and quantity of EHR data a

297 sease incidence requires approaches that can tackle varying spatial and temporal resolutions of each

298 olicies, suggesting that inequalities can be tackled with appropriate social and economic interventio

299 rm or reject a candidate structure) has been tackled with artificial neural network (ANN) mediated mu

300 used widely in 'omics' studies and is often tackled with standard methods, e.g. hierarchical cluster