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1 of a gene are dispersed rather than repeated tandemly.
3 shows that the two BRCT repeats are arranged tandemly and pack extensively through an interface that
6 ed a complex organization in which blocks of tandemly arranged 180-bp repeating units are interrupted
8 wo tyrosine autophosphorylation sites in the tandemly arranged bidentate motif that serve as docking
9 Two portions of MR recognize carbohydrates: tandemly arranged C-type lectin domains facilitate carbo
11 nd xylanolytic enzymes are fused to multiple tandemly arranged carbohydrate binding modules (CBM), fr
14 e use a recombinant protein containing three tandemly arranged copies of C3d and the Ag hen egg lysoz
17 P1-wr, is composed of multiple head-to-tail tandemly arranged copies of the complete gene unit and s
20 mpR binds asymmetrically to the F1 site as a tandemly arranged dimer with each monomer having its rec
24 Analysis of cells containing a vector of tandemly arranged enhanced green fluorescent protein gen
25 logs of the omp gene family were found to be tandemly arranged except for one or two genes with oppos
26 Nearly one-quarter of these genes belong to tandemly arranged families, encompassing more than 25% o
27 n (OMP) multigene locus spanning 6 of the 22 tandemly arranged genes identified three distinct geneti
30 equences encoding the adhesin domains of the tandemly arranged hagA and kgp genes on the chromosomes
35 ant (mekk1/2/3), defective in a set of three tandemly arranged MAP3Ks, was almost insensitive to l-Gl
36 ta are homologous and both contain a pair of tandemly arranged N-terminal modules [thrombospondin typ
38 e or a few GGH genes; Arabidopsis has three, tandemly arranged on chromosome 1, which encode proteins
42 lly reduced level of the transcript from two tandemly arranged pilA genes (sll1694 and sll1695), whic
43 uence analysis of the fragment revealed four tandemly arranged potential open reading frames (ORFs),
47 g the Pi9 locus led to identification of six tandemly arranged resistance-like genes with a nucleotid
51 in which the receptor binding domain has two tandemly arranged subsites for classical ligands, a peri
52 inally, a reporter transgene containing four tandemly arranged TCGTG elements has strong expression i
53 s subsp. tularensis are devoid of classical, tandemly arranged TCS genes, but orphaned members, such
54 riction mapping of one particular stretch of tandemly arranged TR-1 units indicate that these element
55 te motif (Y557INMAVTY564VNL) composed of two tandemly arranged tyrosines in the carboxyl terminus.
59 ly, we demonstrated that both sites 1 and 2, tandemly arranged, are required for efficient DAA for C5
60 patterns of intraspecific variation in three tandemly arranged, testes-expressed genes (janusA, janus
62 able mechanical strength of SasG arises from tandemly arrayed 'clamp' motifs within the folded domain
64 e CS protein TRAP-related protein (CTRP) six tandemly arrayed A domains followed by seven TSP type 1-
66 Crassostrea virginica), which possesses four tandemly arrayed carbohydrate recognition domains, was p
68 ion revealed that TTY2 genes are arranged in tandemly arrayed clusters on both arms of the Y chromoso
69 n blot analyses indicate the presence of six tandemly arrayed copies of the P-4 gene in L. pifanoi; h
70 V) latent cycle promoter Wp, present in each tandemly arrayed copy of the BamHI W region in the EBV g
81 d to be mapped on the same chromosomes, with tandemly arrayed genes significantly biased towards spec
82 s cell carcinoma antigens (SCCA) 1 and 2 are tandemly arrayed genes that encode two high-molecular-we
83 itously and abundantly expressed of the five tandemly arrayed genes, and their messages are present i
85 herin-related protocadherin (Pcdh) genes are tandemly arrayed in three clusters (alpha, beta, and gam
86 chitecture; each protein is comprised of two tandemly arrayed LIM domains, protein-binding motifs fou
88 reater multiples of the F-type motif, either tandemly arrayed or in mosaic combinations with other do
89 lmost entirely of a few massively amplified, tandemly arrayed repeats, some of which can recombine wi
90 plant Helitrons amplify by RCR and that the tandemly arrayed replication products accumulate mostly
91 n maintains at near identity the hundreds of tandemly arrayed ribosomal RNA (rRNA) genes and their sp
92 ns share a common domain organization of two tandemly arrayed RNA recognition motifs (RRMs) near the
93 We demonstrated that synthetic genes with tandemly arrayed tRNA-gRNA architecture were efficiently
96 bind to appendages relatively weakly but, as tandemly arrayed within the SJ170 extension, can coopera
98 cal footprinting analysis revealed that ResD tandemly binds to the -41 to -83 region of hmp and the -
99 jority of duplicated genes are not clustered tandemly, but instead are dispersed in syntenic regions
100 ploblocks that are significantly enriched in tandemly clustered secretory pathogenesis determinants.
102 An intriguing example is provided by the tandemly duplicated beta-globin genes of deer mice (Pero
103 Many species-specific duplication events and tandemly duplicated clusters clearly demonstrated that s
104 e single- and double-knockout mutants of two tandemly duplicated cytochrome P450 genes, SPS/BUS/CYP79
105 a mutation that simultaneously disrupts the tandemly duplicated Drosophila ph transcriptional units.
106 rms are deficient for cooperative binding to tandemly duplicated elements, indicating that the L1 loo
107 unpaired inversions and deletions connect a tandemly duplicated ERBB2 with neighboring 17q21.3 ampli
108 tractable model for coordinate regulation of tandemly duplicated gene families that are commonly foun
109 AP kinase kinase kinase and is a member of a tandemly duplicated gene family with MEKK2 and MEKK3.
110 cally involving deeply conserved clusters of tandemly duplicated genes (e.g., Hox genes and histones)
111 y of the Chlamydia genomes and prevalence of tandemly duplicated genes are evidence of minimal chromo
113 recent whole genome duplication to a set of tandemly duplicated genes in the model forest tree Popul
114 In this article, I consider families of tandemly duplicated genes that show 'microfunctionalizat
115 was identified as part of an array of eight tandemly duplicated genes, and AcTPS1 expression and ter
116 the Unpaired (Upd) family, encoded by three tandemly duplicated genes, is the only class of ligands
121 imes overexpressed in resistant females, are tandemly duplicated in the BAC clone as well as in labor
122 and Col4a4 include a 19-bp element that was tandemly duplicated in the human lineage and a CTC box e
124 n MDR1 gene product, P-glycoprotein (Pgp), a tandemly duplicated molecule containing two putative ATP
127 ce and humans, 18 of 21 RGS genes are either tandemly duplicated or tightly linked to genes encoding
128 re, we show that increased expression of two tandemly duplicated P450 genes, CYP6P9a and CYP6P9b, is
131 241 to 258 bp of intergenic spacers between tandemly duplicated rrf (5S) and rrl (23S) was amplified
132 e expression pattern of some homeologous and tandemly duplicated soybean genes, supporting their rapi
133 model, transcription of an SNR14 allele with tandemly duplicated start sites initiates primarily from
136 singletons" were found to be more frequently tandemly duplicated than "duplicates" in soybean, which
138 g (CTG.CAG)(n) (17-175 units in length) were tandemly duplicated when propagated in plasmids in Esche
141 t that a disabling mutation in one copy of a tandemly duplicated, diaphanous-related formin is perfec
143 sed intronless gene (with a polyA tail and a tandemly-duplicated 13 bp insertion site in the genome)
144 egulatory pathways than they are to function tandemly in a single pathway as thought previously.
146 possible subunit arrangements by expressing tandemly linked dimers of both subunits and examining th
147 We report here the x-ray structure of three tandemly linked domains of MHV nsp3, including the papai
149 ons for gene activation from a promoter with tandemly linked GAS motifs can be relieved by strengthen
151 fferentiation may be enhanced in cases where tandemly linked genes contribute to fitness variation.
152 genomes of these viruses contain a series of tandemly linked genes separated by intergenic (IG) seque
153 ocus is composed of a six-membered family of tandemly linked genes whose complex regulation plays a c
161 In Arabidopsis three CBF genes, present in a tandemly-linked cluster, are induced by low temperatures
163 al deletion of genomic sequences between the tandemly located TMPRSS2 and ERG gene sequences on chrom
166 a, of 528 bp, whereas CentPv2 is composed of tandemly organized monomers; (ii) CentPv1 and CentPv2 ha
169 ipate in inter-keratin disulfide bonding and tandemly play a key role complementary to that of Cys-36
170 in which the stepwise phosphorylation of two tandemly positioned residues near the C terminus mediate
171 han proteins in which activation domains are tandemly reiterated in the same polypeptide chain, becau
173 nking the pectoral muscle-specific exons, is tandemly repeated 4 times and once partially, providing
174 d chromatin model systems reconstituted from tandemly repeated 5 S rDNA, histone H5, and either nativ
179 4 and ng1 genes, noncoding RNAs derived from tandemly repeated alphabeta/alphagamma elements within a
180 on the chromosomes that contained internal, tandemly repeated amino acid sequences that were absent
181 composed of, or contain domains composed of, tandemly repeated amino acid sequences with a consensus
182 characterized plasmodial antigens, blocks of tandemly repeated amino acids are lacking in the pypAg-2
183 s (rDNA) encoding ribosomal RNAs (rRNAs) are tandemly repeated and give origin to the nucleolus.
186 like other organisms, LmQDPR is encoded by a tandemly repeated array of 8-9 copies containing LmQDPR
190 the primary structure of mefp1 consists of a tandemly repeated consensus sequence Ala(1)-Lys(2)-Pro(3
192 genes, which consists of a central domain of tandemly repeated copies of a 108-bp motif, an upstream
193 ength variants contain within their ULRs two tandemly repeated copies of a 28-bp region of dyad symme
194 est subunit of RNA polymerase II consists of tandemly repeated copies of a heptapeptide with the Y(1)
195 to analyze a series of constructs containing tandemly repeated copies of the PR promoter, with the re
196 ), which is encoded in a variable number of tandemly repeated copies, giving rise to numerous apo(a)
197 vA possesses subterminal inverted repeats, a tandemly repeated core element, a tetranucleotide micros
199 e case of d(T(4)G(4)T(4)G(4)), which has two tandemly repeated d(TTTTTGGGG) telomere motifs, two bind
200 ar mass (approximately 92 kDa) and number of tandemly repeated decapeptides, and contained the same p
204 Relative to most regions of the genome, tandemly repeated DNA sequences display a greater propen
206 n of tra-2 mRNA in C. elegans is mediated by tandemly repeated elements in its 3'UTR; these elements
207 ound in patients: CD8+ CTLs, which recognize tandemly repeated epitopes on the MUC1 protein core, and
208 Exon repetition describes the presence of tandemly repeated exons in mRNA in the absence of duplic
209 Exon repetition describes the presence of tandemly repeated exons in mRNA in the absence of duplic
210 ely 17%) of Arabidopsis genes are members of tandemly repeated families and pose a particular challen
211 ode other pMGA family members suggest that a tandemly repeated GAA sequence may influence pMGA gene e
213 ed ribosomal genes, transposon remnants, and tandemly repeated genes (HXT6/7, ENA1/2/5, and CUP1-1/-2
214 ing tissue culture, our study shows that the tandemly repeated genes are also prone to hypermethylati
216 ructural RNA: the RNU1 and RNU2 loci contain tandemly repeated genes encoding U1 and U2 small nuclear
217 (RNU1, PSU1, RNU2, and RN5S) each containing tandemly repeated genes for an abundant small RNA (U1, U
218 es, RNA polymerase I (pol I) transcribes the tandemly repeated genes that encode the precursor of 18S
219 ap-based approach and found to contain three tandemly repeated genes with the structures of nucleotid
222 ne encoding a putative GTPase containing two tandemly repeated GTP-binding domains from a hyperthermo
223 t RNA polymerase II (RNAP II) is composed of tandemly repeated heptads with the consensus sequence YS
224 verse set of contexts, often embedded within tandemly repeated heptameric sequences or within minitra
227 a TGIF is represented by the products of two tandemly repeated highly similar genes, achintya and vis
229 ernal structures, including approximately 36 tandemly repeated His-rich decapeptides (e.g., HVHTHRVLH
236 h the exception that a 30 nucleotide unit is tandemly repeated in X-linked members but is present onl
237 's expression, with expression patterns from tandemly repeated inserted genes suggesting that the ext
240 455) contained 14 copies of a highly basic, tandemly repeated motif rich in arginine and serine, hav
241 ue-specific pigmentation of maize carrying a tandemly repeated multicopy allele of pericarp color1 (p
242 lain why maintenance of homogeneity within a tandemly repeated multigene family would lead to junctio
243 se slippage occurs frequently in tracts of a tandemly repeated nucleotide, and such slippage events c
244 contain a bZIP DNA binding motif, it binds a tandemly repeated palindromic sequence in the adenovirus
245 receptor-like transmembrane protein with two tandemly repeated phosphatase domains in the cytoplasmic
248 ing features of these phages are a series of tandemly repeated putative tail fiber genes that are sim
249 four cadherin-like ectodomains and a thrice tandemly repeated region enriched in threonine, serine,
250 s hypothesis by examining highly polymorphic tandemly repeated regions of the trypanosome genome, i.e
253 ve focused on the concerted evolution of the tandemly repeated rRNA genes of eukaryotes; however, the
257 ned by this transcript revealed a cluster of tandemly repeated sequence in the human, orangutan, and
258 of a 35-bp mitochondrial DNA (mtDNA) D-loop tandemly repeated sequence in the populations of a North
259 have similar numbers of genes, with abundant tandemly repeated sequence motifs, and transposable elem
267 e discovery that a large number of loci with tandemly repeated sequences in human and many eukaryote
268 creased intramolecular recombination between tandemly repeated sequences of rho(-) mtDNA to produce s
269 binational repair of double-strand breaks in tandemly repeated sequences often results in the loss of
270 ported proteins containing short lysine-rich tandemly repeated sequences that are sufficient to local
271 eosome to 'regional' centromeres embedded in tandemly repeated sequences to holocentromeres that exte
277 findings help to explain the conservation of tandemly repeated switch regions associated with heavy c
279 onal genome features include an abundance of tandemly repeated transfer-RNA-containing arrays, which
280 ed to compare the avidity of peptide motifs, tandemly repeated two or four times, and single motifs s
281 of Arabidopsis, AtCon, is composed of 178-bp tandemly repeated units and is located at the centromere
284 terminal domain (CTD), which is comprised of tandemly repeated Y(1)-S(2)-P(3)-T(4)-S(5)-P(6)-S(7) ami
286 ism in Britain was the insertion of a large, tandemly repeated, transposable element into the first i
287 sis and L. major: in L. major the LCTASs are tandemly repeated, while in L. braziliensis the LCTAS is
290 ion melting curves of well-behaved synthetic tandemly repeating inserts in recombinant pN/MCS plasmid
292 insulin gene, comprises a variable number of tandemly repeating sequences related to ACAGGGGTGTGGGG.
293 terminal repeats each consisting of several tandemly repeating units and a 5' single-stranded extens
294 polymerase II in eukaryotes is comprised of tandemly repeating units of a conserved seven-amino acid
297 Minisatellite and microsatellite are short tandemly repetitive sequences dispersed in eukaryotic ge
298 nd depends on whether the genomic context is tandemly repetitive sequences often found near centromer
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