ライフサイエンスコーパス: targeting

1 titative and qualitative nature of STAT-gene targeting.

2 g as a fiducial marker for precise radiation targeting.

3 evant to SZ pathology in order to inform DBS targeting.

4 es and limit the efficacy of individual gene targeting.

5 nnels lacking a signal sequence for membrane targeting.

6 pathways that may be amenable to therapeutic targeting.

7 a 27-mer fragment, consistent with mismatch targeting.

8 of-of-concept, we delivered short guide RNAs targeting 3 genes critical for cardiac physiology, Myh6,

9 shown by using the tumor-specific, integrin-targeting (90)Y-DOTA-RGD and the localized activation of

10 We report here that targeting a completely different process, autophagy, can

11 his study is the first proof of concept that targeting a lncRNA to transcriptionally activate SMN2 ca

12 esults suggest that new experimental designs targeting a majority of inhibitory neurons may be able t

13 An RT-RPA assay targeting a recent epidemic human norovirus strain (GII.

14 We reasoned that targeting a redox cycling nitroxide to mitochondria coul

15 herapeutic agents in preference to compounds targeting a single receptor or enzyme.

16 ntly, the ICG-EPI NPs showed excellent tumor targeting ability with high spatial resolution and deep

17 NPs without compromising the peptide's brain targeting ability.

18 CP based on the readiness of the individual; targeting ACP content as the individual's health conditi

19 0f inhibited tumor cell invasion by directly targeting ADAM9, the TGFbeta receptor TGFBR2 and the EMT

20 Targeting ADCC-Abs to internal proteins may be a potenti

21 revent or overcome drug resistance to single targeting agents.

22 Gene silencing experiments targeting alpha1D reduced the migration and the basal cy

23 educed considerably by degenerate primers or targeting amplicons with conserved priming sites.

24 d pharmacologic and/or transgenic approaches targeting an individual hormone/mediator have yielded so

25 nucleosomes, likely through a combination of targeting and allosteric regulation.

26 ane protein functions, or involved with drug targeting and delivery.

27 nti-EGFR GA201 mAb were tested for selective targeting and eradication of double-positive human NCI-H

28 izing these nanostructures with moieties for targeting and fluorescence, characterizing their biophys

29 In vivo tumor targeting and pharmacokinetics of the radiotracers were

30 was impaired, leading to increased lysosomal targeting and reduced surface levels on CD4(+) T cells o

31 smembrane segments of RHD3 are essential for targeting and retention of RHD3 in the ER and can also f

32 for sequence evolution with implications for targeting and secondary structure.

33 The role of mature domains in targeting and secretion is unclear.

34 proteins frequently affecting their membrane targeting and trafficking.

35 cA is necessary and sufficient to direct the targeting and translocation of RodZ to the bacterial pla

36 ith the cholera toxin B domain (CTB) for RGC-targeting and with Cy5.5 for unimNP-tracing.

37 lity and enhanced susceptiblity to cell wall targeting antibiotics.

38 humans, and that administration of cis P-tau targeting antibody to rodents reduces or delays patholog

39 both BCMA and TACI in the presence of a BCMA-targeting antibody.

40 ctural insight for therapeutic interventions targeting AP-1 proteins.

41 The power of targeting APC was further demonstrated by the complete n

42 Using a conditional targeting approach, we ablated the major CLP gene Irf6 o

43 hobiont-induced changes in microbiota immune targeting as a new concept in IBD diagnotics.

44 The position of the radiolabel influences targeting as well, although to a lesser extent.

45 In vitro reconstitution and in vivo targeting assays show that SecA is necessary and suffici

46 erases (PARP) that regulate Wnt signaling by targeting Axin for degradation.

47 view highlights the therapeutic potential of targeting B7-H4.

48 ng role of BCL6 and provide the rationale of targeting BCL6 as a potential therapeutic approach.

49 et sequences at an average ratio of 29.2% by targeting both DNA strands simultaneously with an over 9

50 thways, and suggest that therapeutic designs targeting both pathways will be more effective at slowin

51 invasion to proliferation, and suggest that targeting both receptors with STAT3 signaling inhibitor

52 egulated by endosomal recycling and vacuolar targeting, but the role of vacuole-related proteins in B

53 egulation of this post-translational mode of targeting by cpSRP remain unclear.

54 Recent studies have shown enhanced tumor targeting by novel somatostatin receptor (SSTR) antagoni

55 reased risk of cancer and Parkinson disease, targeting C5aR1 may serve as a treatment option for pati

56 ss, the pHLIP technology may prove useful in targeting cancer cells and metastases for tumor diagnosi

57 We then demonstrated the powerful multiplex targeting capacity of CRISPR/Cas9.

58 b vedotin (BV) is an antibody-drug conjugate targeting CD30.

59 epine dimers linked to a monoclonal antibody targeting CD33, which is expressed in the majority of ac

60 (LT5.J4b12C) to non-neutralizing antibodies targeting CD4-induced Env epitopes in the presence of so

61 breakage and the formation of micronuclei by targeting cellular ligases through a sT domain that also

62 peripheral sensory input may prevent BTP and targeting central sites may be required for pain relief

63 We therefore concluded that targeting chemokines with antibodies such as 1B6 that re

64 , comparative sequence analysis specifically targeting chemoreceptor regions involved in pathway inte

65 Further investigation of drugs targeting chromatin regulators is warranted in HPV-negat

66 urther development of cathepsin G inhibitors targeting chronic inflammatory disorders.

67 12 cells with an inducible short hairpin RNA targeting clathrin heavy chain, resulting in approximate

68 s were randomized to a teaching intervention targeting cognitive skills needed to challenge a superio

69 ilable because of the unstructured states of targeting-competent preproteins.

70 as to the prostate-specific membrane antigen-targeting compound RPS-070.

71 d safe-targeting guides), in addition to non-targeting controls.

72 Herein, we designed a fibronectin-targeting CREKA-modified liposomal doxorubicin (CREKA-Li

73 ect CRC pathogenesis and development through targeting critical genes in cellular system.

74 However, targeting CXCL1, CXCL6 and CXCL8 3'-UTRs unexpectedly le

75 Additional trials of medications aimed at targeting cytokine overactivity that act directly on bra

76 Finally, we showed that ABCD4 lysosomal targeting depends on co-expression of, and interaction w

77 ized by a universal immune defense mechanism targeting diverse pathogens replicating in cytosolic mem

78 1 is mediated by its conserved mitochondrial targeting domain (MTD), which, in unstressed conditions,

79 ses with 11 actin regulators and three actin-targeting drugs suggest that PMS contains short actin fi

80 ort that PTCL are sensitive to transcription-targeting drugs, and, in particular, to THZ1, a covalent

81 therapeutic miRNA capable of simultaneously targeting dysregulated polyamine metabolism in cancer, t

82 simultaneously delivering miR-34a mimic and targeting dysregulated polyamine metabolism in cancer.

83 ing of PCR amplicons generated using primers targeting either ketosynthase domains from polyketide bi

84 Our findings provide evidence that targeting endogenous spatiotemporal dynamics is a potent

85 Thus, our findings suggest that targeting endothelial LPP enhances the efficacy of chemo

86 Here, we screened a panel of small molecules targeting epigenetic modulators against human metastatic

87 We interpret these inputs as dendrite-targeting excitation and soma-targeting inhibition (the

88 th drisapersen, an antisense oligonucleotide targeting exon 51: an open label study including 12 pati

89 Measuring and targeting F. nucleatum and its associated pathway will y

90 Targeting fibrinogen or its downstream BMP signaling pat

91 Moreover, we show that targeting FimH with M4284, a high-affinity inhibitory ma

92 From midanaphase, the targeting function of Gin4 is taken over by the bud neck

93 Targeting G-quadruplex DNAs for cancer treatment is a ve

94 Thus, targeting Gal-1-glycan interactions may contribute to re

95 Targeting gdf3 and ndr2 RNA to specific lineages indicat

96 etus for the development of malaria vaccines targeting GLURP.

97 ytosolic NAD, and that therapies designed at targeting glycolysis must consider both dehydrogenases.

98 Furthermore, sgRNA targeting GPI anchor protein pathway genes induced loss

99 DNA and adenovirus (Ad5) combination regimen targeting guanylyl cyclase C (GUCY2C), a receptor expres

100 The safe-targeting guides allow for proper control of toxicity fr

101 n-functional, non-genic regions (termed safe-targeting guides), in addition to non-targeting controls

102 nic acid 2-O-sulfate residues as selectively targeting HCII.

103 A combined approach targeting HDAC1/HDAC2 and MYC may present a novel and mo

104 gets in breast and gastric cancer but agents targeting Her2 have not yet demonstrated anti-tumor acti

105 remedy some of the major problems in cancer targeting: heterogeneity, change in phenotype during dis

106 nt genes and can be combined with inhibitors targeting histone methylation for synergistic effects wh

107 generated the bispecific antibody MCLA-128, targeting human EGF receptors 2 and 3.

108 F1 and the potential therapeutic application targeting IF1 remain obscure.

109 Neurons electroporated with a shRNA targeting IGF-1 receptor failed to migrate to the upper

110 Finally, cells electroporated with the shRNA targeting IGF-1 receptor were unable to form an axon and

111 ted systemically for 6 weeks with antibodies targeting IL-17A, IL-17RA, IL-12/23p40, or IL-23p19.

112 with placebo or MABp1, a true human antibody targeting IL-1alpha.

113 Although some clinical trials targeting immune checkpoints have shown success, the mol

114 structures presents many potential sites for targeting in therapeutic interventions.

115 ts as dendrite-targeting excitation and soma-targeting inhibition (the latter contributes non-dipole-

116 cted these cells with small interfering RNAs targeting inhibitory SMADs to analyze gene expression pr

117 re, we use optical tissue clearing and a TAM-targeting injectable fluorescent nanoparticle (NP) to ex

118 first specific treatment for IgA nephropathy targeting intestinal mucosal immunity upstream of diseas

119 To investigate the clinical application of targeting JAK for ALK- ALCL, we treated ALK- cell lines

120 Cellular proteins regulating and targeting lentiviral and gammaretroviral integration in

121 en limiting factors in realizing the goal of targeting leukemic stem cells (LSCs).

122 etection using highly selective BiDz sensors targeting loci associated with species typing and resist

123 local inflammation and glucose metabolism by targeting macrophages and adipocytes, respectively.

124 view, with implications for therapeutically targeting Mdm2.

125 lts demonstrate the therapeutic potential of targeting metabolic pathways in the treatment of inflamm

126 Our results support the rationale for targeting metabolism in sepsis with recombinant human IL

127 bolic plasticity and design cancer therapies targeting metabolism.

128 Drugs targeting metabotropic glutamate receptor 5 (mGluR5) hav

129 new tool to monitor the effect of therapies targeting microglia/macrophages activation after TBI.

130 tor Nix interacts with LC3/GABARAP proteins, targeting mitochondria into autophagosomes for degradati

131 The corresponding probes selectively targeting mitochondria, lysosomes, and F-actin demonstra

132 rphan nuclear receptor, induces apoptosis by targeting mitochondria.

133 ied, minimal consideration has been given to targeting mitochondrial glutamate metabolism to control

134 itted client-SGTA complex, a self-sufficient targeting module, and an embedded but self-sufficient qu

135 for the first time as late-stage gametocyte-targeting molecules.

136 Oligonucleotides targeting mouse Angptl3 retarded the progression of athe

137 Targeting mRNAs to distinct regions of the cytoplasm con

138 This raises the possibility of targeting MT dynamics in the design of new therapeutic a

139 Our findings demonstrate that targeting mTOR-dependent M2 cells is critical for preven

140 ed into MUC1 transgenic mice, we showed that targeting MUC1-C associated with PD-L1 suppression, incr

141 tributes to the DNA damage response (DDR) by targeting multiple factors downstream of the core respon

142 A combination of interventions targeting multiple steps in the continuum is needed to a

143 y provides a unique strategy for selectively targeting MYC transcription by pharmacological means as

144 s and evaluates new cancer targets for tumor-targeting nanomedicine.

145 udies assessing the therapeutic potential of targeting Nck in aggressive cancers.

146 mechanisms and immunotherapeutic approaches targeting neoantigens.

147 hil-platelet interactions in AMI patients by targeting neutrophils.

148 Targeting newborn dendritic cells (DCs), which integrate

149 Thus, pharmacotherapy targeting NMDA receptors may inadvertently produce subst

150 per gene and thousands of negative controls targeting non-functional, non-genic regions (termed safe

151 Monoclonal antibodies (mAbs) targeting Notch protein activity have already moved into

152 These findings raise the possibility that targeting NRP1 or its NCD interactors may be a useful th

153 c PMCA in part reproduces the specific brain targeting observed in experimental, acquired, and sporad

154 Targeting of a constitutively active FoxM1 construct or

155 y have clinical significance, as therapeutic targeting of a signaling pathway such as NG2/CSPG4 may h

156 Furthermore, intestinal targeting of Baf180 renders mice susceptible to a more a

157 The efficacy of dichroic targeting of chiral nanostructures for biomedical applic

158 y complex molecules by small interfering RNA targeting of class II transactivator can reduce the capa

159 Our findings demonstrate concurrent targeting of different DNA secondary structures offers a

160 d as a model illustrating how interdependent targeting of different silencing pathways can potentiate

161 Therapeutic targeting of endothelial FABP4 by siRNA in vivo has anti

162 s genes, including Sox17, shifts the genomic targeting of Fli1 to favour nearby Sox consensus sites a

163 2 Ser-409 phosphorylation inhibited synaptic targeting of GluK1 because, unlike WT Neto2 and the phos

164 These findings suggest that targeting of GPX4 may represent a therapeutic strategy t

165 allelic regulatory activity, and CRISPR/Cas9 targeting of human chondrocytes demonstrates that the re

166 In light of the beneficial targeting of IL-23/12 in patients with IBD, 1,25D appear

167 step in the care cascade enables appropriate targeting of interventions and resources.

168 le diagnostic methods that can enable better targeting of interventions.

169 the nanoparticle characteristics that enable targeting of invasive GBM cells.

170 cancer-specific metabolic vulnerability upon targeting of its paralogous isoform ME3.

171 eptide in diagnostic imaging and therapeutic targeting of MEMs in solid tumors.

172 ith a low dose of latrunculin A disrupts the targeting of microtubules to cell-cell junctions.

173 Targeting of myeloid-dendritic cell receptor DC-SIGN by

174 ividual 2A(pro) predict RV genotype-specific targeting of NPC pathways and cargos.

175 P32-directed intraperitoneal targeting of other anticancer agents and nanoparticles u

176 Our data show that targeting of p32 with linTT1 tumor-penetrating peptide i

177 rgeted for mechanistic study and therapeutic targeting of peanut allergy.

178 Enhanced expression and membrane targeting of PP2A-C was observed in 5% O2, resulting in

179 Therefore, the targeting of PSMA has become increasingly important over

180 Finally, we demonstrate that co-targeting of ROS1 and EGFR could potentially offer an ef

181 mmunization activities (SIAs) continued, the targeting of settlements at high risk for polio transmis

182 in vitro and in vivo Notably, pharmacologic targeting of SPHK1 or YAP/TAZ was sufficient to inhibit

183 uppression function of p53 in cancer by dual targeting of the negative regulators HDM2 and HDMX.

184 e, we report that genetic or pharmacological targeting of the oncogenic MUC1 subunit MUC1-C is suffic

185 on of their scaffolding abilities and direct targeting of their interaction interfaces to modulate GP

186 ammalian antiviral immunity including direct targeting of viruses and their individual components, an

187 Mitochondrial targeting of Vms1 is mediated by its conserved mitochond

188 ulators of V-ATPase either are restricted to targeting one membranous subunit of V-ATPase or have poo

189 alamus is needed to establish the utility of targeting oxytocin signalling in obesity.

190 Future molecular MRI targeting P-selectin may be used to improve diagnosis, f

191 ies the potential for recovering function by targeting p97 disease mutants with drug molecules.

192 pave the way for small-molecule drug design targeting pain and inflammation.

193 However, targeting PAR1 with an orthosteric-tethered ligand bindi

194 We suggest that targeting PAR4 represents an attractive alternative to b

195 Targeting PARP-associated DNA repair may represent a nov

196 s enveloped virus infections by specifically targeting phospholipids in the lipid bilayer via the pro

197 at suppresses light signaling in darkness by targeting positive regulators of the light response, mai

198 Targeting postulated CD19(+) myeloma stem cells with ant

199 target transcripts but also computes the off-targeting potential of a given siRNA.

200 ies protect against RSV and why specifically targeting prefusion F could have great clinical potentia

201 ed a combination intervention strategy (CIS) targeting prevalent barriers to timely linkage and susta

202 ting truncal events is more efficacious than targeting private events in reducing the tumor burden.

203 ponses that are critical for regeneration by targeting proregenerative P2Y2 nucleotide receptor (P2Y2

204 Targeting protein-protein interaction (PPI) is rapidly b

205 t can artificially display a wide variety of targeting protein/peptide ligands and directly encapsula

206 c interventions on antimicrobial stewardship targeting providers and caregivers substantially reduced

207 simple motif to provide active intracellular targeting provides a promising strategy for directing su

208 in cell and animal models has revealed that targeting RAGE impairs inflammation and progression of d

209 euron spatial resolution even when optically targeting randomly distributed groups of neurons in 3D.

210 in mouse GC B cells, sequence-intrinsic SHM-targeting rates of nucleotides across substrates represe

211 against tumour-cell subpopulations with low targeting receptor levels.

212 ence control confers potential for molecular targeting, recognition and biocatalysis, as well as mole

213 ether, these results suggest that germ plasm targeting represents a fitness strategy adopted by some

214 Tumor targeting results were quantitatively similar at 72 and

215 Targeting signal transduction pathways which promote the

216 cellular context will likely be crucial for targeting signalling networks.

217 mature domains harbor their own independent targeting signals (mature domain targeting signals [MTSs

218 independent targeting signals (mature domain targeting signals [MTSs]).

219 encodes an axon guidance protein, either by targeting slit-1 mRNA or, potentially, by modulating the

220 ile increasingly sophisticated immunotherapy targeting soluble and aggregated brain amyloid-beta (Abe

221 ly tested, in preclinical models, treatments targeting specific resistance mechanisms to sensitize IC

222 ces to examine the effect of variants on the targeting specificity of approximately 3,000 gRNAs acros

223 nd barrier defects were largely corrected by targeting Stard7 to mitochondria or treating epithelial

224 in the design and application of Rho GTPase targeting strategies in future cancer therapies.

225 otic priming in ASFs and explored a combined targeting strategy to deplete senescent cholangiocytes a

226 yclin A/Cdk1 substrate is myosin phosphatase targeting subunit 1 (MYPT1), and we show that MYPT1 loca

227 adigms are described here that have emerged, targeting superior TE materials and higher TE performanc

228 Thus, use of endogenous targeting systems is increasingly gaining momentum.

229 e designed our strategy to select against re-targeting the 'knockout-first' allele and identify essen

230 PCR targeting the 16S rRNA-encoding gene and chaperonin-60 (

231 creases in several disease-related microRNAs targeting the activin A receptor type 1C (ACVR1C), a com

232 gical basis of aging, research suggests that targeting the aging process itself could ameliorate many

233 mulated reactive oxygen species signaling by targeting the antioxidant methionine sulfoxide reductase

234 and implicate a pharmaceutical potential for targeting the APP673 site for AD drug development.

235 ties were analysed using amplicon sequencing targeting the bacterial 16S rRNA V3-V4 region and the cy

236 Despite the development of chemical probes targeting the BRD9 bromodomain, there is a limited under

237 Targeting the catalytic activity of CK2 using the next-g

238 w that ZIKV shows considerable complexity in targeting the CNS and may target different cells at diff

239 orted compounds that inhibit multiple HKs by targeting the conserved catalytic and ATP-binding (CA) d

240 Targeting the CXCL12-CXCR4/CXCR7 axis could lead to nove

241 polymerase chain reaction (PCR) (nested PCR targeting the cytochrome b gene) and quantitative PCR as

242 By targeting the DNA mismatch repair gene MLH1 CGI, we coul

243 ere has been some early success in therapies targeting the downstream inflammatory and oxidative effe

244 rently being assessed in clinical trials are targeting the downstream sequelae of this primary event.

245 variant (UbV) library to develop inhibitors targeting the DUBs USP7 and USP10, which are involved in

246 ral series of pyrazolopyran-based inhibitors targeting the enzyme serine hydroxymethyltransferase (SH

247 rogression, but that LDD events specifically targeting the expansion front are most efficient in supp

248 ugh genetic or pharmacological manipulations targeting the GABAergic network restored gathering behav

249 been successfully treated with therapeutics targeting the IL-1 pathway; however, there are a number

250 ry to define applicability of new strategies targeting the intestinal microbiota.

251 ific PCR and real-time PCR with EvaGreen dye targeting the ITS region of Carthamus tinctorius L.

252 e to investigate the therapeutic efficacy of targeting the MALT1-MYC axis in MCL patients.

253 we have used to delete Oxtr do not rule out targeting the neighboring CA3a region, these findings su

254 variant that escapes neutralization by MAbs targeting the neutralizing epitope (NE) antigenic site.

255 Tyr(308), but disrupted by a S296A mutation, targeting the only other known phosphorylated residue in

256 an autophagy-mediated host response directly targeting the parasitophorous vacuolar membrane (PVM) ha

257 Targeting the pathways that involved in these prognostic

258 tic co-delivery of Cas9 mRNA and dual sgRNAs targeting the PDX1 gene, which when combined with chimer

259 ess suggest that we may, in fact, already be targeting the peripheral EVS.

260 lications for development of novel therapies targeting the precursor mRNA splicing pathway.

261 we demonstrate the therapeutic potential of targeting the RBBP4-BCL11A binding by showing that a BCL

262 onsequences of protein dysfunction; however, targeting the source of that dysfunction, the affected p

263 nt must often be tailored to each patient by targeting the specific mechanisms involved in his or her

264 vel approach to block allergic reactivity by targeting the surface-bound IgE of the allergic effector

265 Agonistic monoclonal antibodies (mAb) targeting the T-cell receptor coregulatory molecule GITR

266 cell DNA replication, indicating that drugs targeting the terminase complex could be safe and select

267 Injection of Cas9-guide RNA-lipid complexes targeting the Tmc1(Bth) allele into the cochlea of neona

268 study suggests that a combinatorial regimen targeting the vasculature, GSCs, and GECs, using drugs a

269 potential of developing new PAI-1- and CCL5-targeting therapy for patients with TNBC.

270 ffinity relationship study for novel ligands targeting these binding sites.

271 tream of proallergic events and suggest that targeting this molecule could be a novel approach to tre

272 inhibitors may have therapeutic potential in targeting this pathway.

273 s the potential efficacy of envisioned drugs targeting this tissue to treat metabolic disease.

274 Targeting this trafficking step has therapeutic promise,

275 ly, these data provide proof of concept that targeting thrombin or fibrin(ogen) may limit pathologies

276 lux towards degradation rather than specific targeting to a singular compartment.

277 Absence of Cet1's NTD decreases FACT targeting to ADH1 and consequently reduces the engagemen

278 mal blood vessels and enhances their passive targeting to cancerous tissues through an enhanced perme

279 s of CO2 for MBF using prospective end-tidal targeting to precisely control arterial Pco2 and PET to

280 pts and that this effect depended on precise targeting to the center of face patches.

281 we previously showed that efficient protein targeting to the INM depends on nucleotide hydrolysis.

282 ubstrate-induced Get3 dynamics in driving TA targeting to the membrane, and reveal a tightly coupled

283 sphorylation at Ser-409 helps restrict GluK1 targeting to the synapse.

284 We used gene targeting to validate candidate genetic factors.

285 g a tetracycline inducible short hairpin RNA targeting TRAF3IP2.

286 n receptor (CAR) T cells expressing EGFRvIII targeting transgene were labeled with a perfluorocarbon

287 equired to realize the full benefits of CFTR-targeting treatments.

288 Targeting Treg cells or CTLA-4 in this precise window ac

289 We show that targeting truncal events is more efficacious than target

290 Modern cancer therapies aim at targeting tumour-specific alterations, such as mutations

291 ct of different RSV immunisation strategies (targeting vaccination for infants, or pregnant women, or

292 All the DC-targeting vaccine administrations with poly-ICLC increas

293 fenib causes a disruption in viral egress by targeting VCP and the secretory pathway, resulting in a

294 , highlighting its potential as a new muscle-targeting vector.

295 T cells targeting viral tumor antigens did not display preferent

296 To examine the mechanisms of DAT filopodial targeting, we used quantitative live-cell fluorescence m

297 l by 2030, optimal intervention planning and targeting will require understanding of trends and rates

298 We enhanced the dCas9-MS2 anchor for genome targeting with Fkbp/Frb dimerizing fusion proteins to al

299 also highlights the therapeutic potential of targeting YAP-BCAR4-glycolysis axis for breast cancer tr

300 tected, but intracameral injection of siRNAs targeting ZO-1 and tricellulin increased outflow facilit