ライフサイエンスコーパス: tear

1 iod following diagnosis of the first retinal tear.

2 risk factor for medial degenerative meniscal tear.

3 ry reported in conjunction with the incident tear.

4 ent of patients with a degenerative meniscus tear.

5 nce of scrolled RPE or other signs of an RPE tear.

6 network was less stable, incomplete, and/or torn.

7 sisting force until the capsulotomy edge was torn.

8 gation of choice for diagnosing rotator cuff tears.

9 imulating the glucose concentration in human tears.

10 e correlated to results of the MMP-9 test in tears.

11 tions and higher rates of posterior capsular tears.

12 ow-up for intrameniscal signal intensity and tears.

13 dings of medial elbow pain, including 53 UCL tears.

14 rs was 98.4% and 95.9% for partial thickness tears.

15 ickness tears and 0.90 for partial thickness tears.

16 of first choice for evaluating rotator cuff tears.

17 c cells (DCs), and a reduced volume of basal tears.

18 %, and 87%, respectively, for diagnosing UCL tears.

19 irect and indirect MR arthrography) and SLAP tears.

20 ormed in patients with acute PVD and retinal tears.

21 and in differentiating partial from complete tears.

22 acy of US and MRI in diagnosing rotator cuff tears.

23 quence, their products appeared in the mouse tears.

24 ived more injections than control eyes after tearing.

25 ed with NMFP, while UWFI detected 25 retinal tears (0.3%; P < .001), 54 lattice and peripheral degene

26 et of illness: saliva (22 days), conjunctiva/tears (28 days), stool (29 days), vaginal fluid (33 days

27 cuity had improved in early tears before the tear (+5.6 letters from baseline; P = 0.01), decreased i

28 nificantly lower in early compared with late tears (53.6 vs. 63.4 letters; P = 0.009).

29 nificantly lower VA than control eyes before tearing (55.5 vs. 66.9 letters; P < 0.001).

30 ge = 1-5); 20.8% presented bilateral retinal tears; 59.1% were myopic eyes (p < 0.05).

31 ; P = 0.01), decreased immediately after the tear (-8.3 letters; P = 0.002), then recovered with no d

32 mous for its regenerative capabilities, must tear a hole through its epithelial tissue each time it o

33 adius of curvature of order 10 nm results in tearing across the tube upon heating, highlighting the r

34 Retinal pigment epithelium tears act differently depending on when they occur.

35 used to evaluate the risk of medial meniscal tear, adjusting for age, sex, body mass index, and knee

36 to check if ZIKAV could be detected in human tears after the first week of infection.

37 38/55 eyes [69%]), and as late tears if they tore afterward (17/55 eyes [31%]).

38 r AEs included 119 (0.55%) cases of capsular tear and 73 (0.34%) cases of vitreous loss.

39 mptoms are caused by a degenerative meniscus tear and prompt caution in using patients' self-report o

40 on scars, ora tooth, cryopexy scars (retinal tear and treated retinoblastoma scar), bone spicules, wh

41 t of association was 0.91 for full thickness tears and 0.90 for partial thickness tears.

42 yme, available in secretions such as saliva, tears and human milk.

43 ing results in the diagnosis of rotator cuff tears and in differentiating partial from complete tears

44 e will be discussed in reference to meniscal tears and injuries of the cruciate ligaments as well as

45 t and the release of antimicrobials into the tears and protected the eye from pathogenic Candida albi

46 Visual acuity, time to tear, and injections received.

47 t baseline, before and immediately after the tear, and then 12 and 24 months later.

48 (VA), lesion size, treatment duration before tearing, and duration of follow-up.

49 and a specificity of 100% for full-thickness tears, and a sensitivity of 89.7% and a specificity of 9

50 Zika virus is present in urine, saliva, tears, and breast milk, but the transmission risk associ

51 e data on the natural course of PVD, retinal tears, and lattice degeneration were used to quantitate

52 Beside GA and characteristic RPE-tears, another atypical form of RPE-defect with overlyin

53 ion can withstand before individual ants are torn apart.

54 ng, in which solidification cracking and hot tearing are also common issues.

55 Meniscal and ligamentous tearing are the most frequent indications for surgical i

56 In acute PVD, retinal tears are prevalently associated with peripheral vitreou

57 Patients were using artificial tears as needed.

58 ssion estimated a breakpoint for the time to tear at 182 days.

59 eoarthritis (OA) and without medial meniscal tear at baseline were studied.

60 Visual acuity had improved in early tears before the tear (+5.6 letters from baseline; P = 0

61 e defined eyes as having early tears if they tore before the breakpoint (38/55 eyes [69%]), and as la

62 tival staining (1.4 vs 0.3, P < 0.0001), and tear break-up time (5.7 vs 8.5 s, P < 0.0001).

63 ad test, conjunctival hyperemia, fluorescein tear break-up time, corneal fluorescein staining, conjun

64 and posttraumatic stress disorder scores and tear breakup time (DEQ5 model: R = 0.54; OSDI model: R =

65 cluding ocular surface disease index (OSDI), tear breakup time (TBUT), corneal fluorescein staining,

66 90, there were also relative improvements in tear breakup time and ocular bulbar redness, compared wi

67 urning (R = 0.41; P < .001), and PTSD score, tear breakup time, and hot pain temporal summation at th

68 estionnaire, tear osmolarity, Schirmer test, tear breakup time, conjunctival hyperemia, staining of t

69 assessed by tear osmolarity, Schirmer test, tear breakup time, corneal and conjunctival staining, an

70 pressant medications (P = .045) but not with tear breakup time, corneal fluorescein staining, or ocul

71 agnostic tests for dry eye syndrome, such as tear breakup time, Oxford Schema, Schirmer's test I, and

72 ity did not decrease significantly after the tear, but continued to decline compared with control eye

73 , whereas the biofilm responds to mechanical tear by synthesizing a silk protein engineered to self-a

74 biosensor is developed to detect glucose in tear by using fluorescence resonance energy transfer (FR

75 Levels of 16 molecules were analyzed in tears by multiplex immunobead analysis.

76 superior labrum anterior-to-posterior (SLAP) tears by using a systematic review and meta-analysis.

77 ct MR arthrography for the detection of SLAP tears, by using surgical findings as the reference stand

78 easured through a number of outcomes such as tear clearance, goblet cells density and corneal epithel

79 Retinal tears complicating the course of a posterior vitreous de

80 mesenteric hematoma formation or mesenteric tear complications.

81 These changes in tear composition, in some cases combined with systemic f

82 Tear concentrations increased for interleukin-1 receptor

83 manufacturing techniques (orthodox, "crush, tear, curl").

84 manufacturing techniques (orthodox, "crush, tear, curl").

85 Tear cytokine concentrations were also measured in the t

86 Tear cytokines levels were determined and included inter

87 their potential for treating severe cases of tear deficiency.

88 Aqueous tear-deficient dry eye is a multifactorial chronic disor

89 In addition, MUC5AC concentration in tears depends on goblet cell density in the conjunctiva

90 Cases were defined as eyes in which an RPE tear developed during treatment.

91 aging, and indirect MR arthrography for SLAP tear diagnosis were 80.4%, 63.0%, and 74.2%, respectivel

92 gnificantly lower tear production and higher tear drainage obstruction.

93 eflectance identified typical hyporeflective tear-drop parafoveal lesions, which corresponded to OCTA

94 The dominant feature is Sputnik Planitia-a tear-drop-shaped topographic depression approximately 1,

95 Increased tear evaporation, tear hyperosmolarity, increased ocular

96 risons of VA and injections received between tear eyes and control eyes were performed at baseline, b

97 Late tear eyes had significantly lower VA than control eyes b

98 Both early and late tear eyes received more injections than control eyes aft

99 ocular disorder characterized by an abnormal tear film and ocular surface.

100 CFTRact-K089 showed sustained tear film bioavailability without detectable systemic ab

101 ols, documented baseline measures (including tear film biomarkers and quality of life).

102 disease index (OSDI) score of more than 12, tear film break-up time (TBUT) of 10 seconds or less, Sc

103 nts were corneal fluorescein staining (CFS), tear film break-up time (TBUT), Schirmer test results, a

104 The outcome measures included Schirmer test, tear film break-up time and OSDI score.

105 Similar results were reported in the tear film break-up time in XG/CS (5.5 +/- 2.1 vs 7.4 +/-

106 rrected visual acuity (BCVA), Schirmer test, tear film breakup time (TBUT), conjunctival congestion,

107 BCVA), tear osmolarity, the Schirmer I test, tear film breakup time (TBUT), corneal and conjunctival

108 njunctival staining, conjunctival hyperemia, tear film breakup time (TBUT), tear osmolarity, and the

109 ers that include allergic conjunctivitis and tear film disorders is associated with its high frequenc

110 e, demographics, comorbidities, medications, tear film factors, and QST metrics) dropped out of these

111 Tear film impairment (aqueous and lipid) and lacrimal dr

112 ds that target CFTR can correct the abnormal tear film in dry eye.

113 filtration of CD4(+) lymphocytes, leading to tear film instability and destructive inflammation.

114 nts a heterogeneous group of conditions with tear film insufficiency and signs and/or symptoms of ocu

115 We did not find differences in tear film osmolarity between the operated eyes and the f

116 most notable new diagnostic tests in DED are tear film osmolarity, inflammatory biomarkers, and meibo

117 By month 3, visual outcome, symblepharon, tear film status, and lid abnormalities were comparable

118 s a recapitulation of the ocular surface and tear film system, which can be further developed as a mo

119 The tear film was analyzed for MMP-9 by a commercially avail

120 e epithelial changes further destabilize the tear film, amplify inflammation, and create a vicious cy

121 hich attempt to modify the properties of the tear film.

122 ine concentrations were also measured in the tear film.

123 itulates the aqueous and mucin layers of the tear film.

124 rs that promote an unstable and hyperosmolar tear film.

125 revealed persistent traction on the retinal tear flap in 19 and 15 eyes, respectively.

126 ontrols were assessed by Schirmer's test for tear flow.

127 nM, which when delivered topically increased tear fluid secretion in mice and showed efficacy in an e

128 In vivo pharmacokinetic studies in rabbit tear fluid showed significant increase in mean residence

129 decreased the presence of burning sensation, tearing, foreign body sensation, conjunctival hyperemia

130 ngly suggested that protruding particles get torn from oil droplets and carry oil with them, causing

131 with respect to full thickness rotator cuff tears (FTT).

132 .0015% showed similar safety with regards to tear function and corneal status and a similar tolerabil

133 orneal microstructure but no side effects on tear function except for an increased tear instability i

134 iglaucoma medications on corneal surface and tear function have been widely shown in literature; it's

135 e ocular surface disease, as demonstrated by tear function parameters (two studies).

136 oFIA) through passive pumping for performing tear glucose analyses in a simple, rapid and inexpensive

137 The tear glucose analysis is an important alternative for th

138 gh cost and complex manufacturing process of tear glucose analyzers combined with the need to exchang

139 efficiently employed in the determination of tear glucose in non-diabetic volunteers, obtaining a clo

140 mmol/L to 3mmol/L, which covers the range of tear glucose levels for both diabetics and healthy subje

141 ducing the costs of the analyses, making the tear glucose monitoring more accessible for the populati

142 Increased tear evaporation, tear hyperosmolarity, increased ocular surface staining,

143 e breakpoint (38/55 eyes [69%]), and as late tears if they tore afterward (17/55 eyes [31%]).

144 We therefore defined eyes as having early tears if they tore before the breakpoint (38/55 eyes [69

145 tests prevent widespread application of the tear in glucose monitoring.

146 points, the signal intensity progressed to a tear in the same segment, and in a single knee, the tear

147 s tears in 25 patients and partial-thickness tears in 15 patients.

148 USG showed complete-thickness tears in 25 patients and partial-thickness tears in 15 p

149 ception of a reduced rate of severe perineal tears in out-of-hours vaginal deliveries.

150 patients that presented one or more retinal tears in the evolution of a symptomatic PVD, with a mini

151 There was a higher incidence of retinal tears in the pre with respect to post-equatorial areas (

152 Resealing of tears in the sarcolemma of myofibers is a necessary step

153 Twenty eyes presented retinal tears in the superior quadrants with respect to only 6 i

154 or blepharitis, meibomian gland capping) and tear inflammatory cytokine levels.

155 cts on tear function except for an increased tear instability in PF Timolol 0.1% group.

156 Investigation of cuff tears is based on ultrasonography (US) and magnetic reso

157 However, the diagnosis of rotator cuff tears is controversial.

158 ilated postoperative examination for retinal tears is recommended in the first 2 months after surgery

159 he patient's response to therapy than to the tear itself.

160 improvements in DED symptoms and lower basal tear levels of interleukin 17A, relative to placebo.

161 Basal tear levels of the proinflammatory cytokine interleukin

162 Retinal tear location and persistent traction on the retinal fla

163 term visual outcomes in eyes affected by RPE tearing may be related more to the patient's response to

164 Multiple retinal tears may be diagnosed in the evolution of a PVD.

165 Tear meniscus height (TMH) was measured by anterior segm

166 Additionally, OCT measurements of the tear meniscus height within the punctum may be related t

167 hthalmos, eyelid laxity, MGD, Schirmer test, tear meniscus height, and dye disappearance test were as

168 Patients with epiphora had a higher tear meniscus within the punctum compared with healthy c

169 Resection of a torn meniscus has no added benefit over sham surgery to

170 between nonlocal transport and neoclassical tearing modes (NTMs) during transient nonlocal heat tran

171 let cell density (r = -0.174, P = 0.036) and tear MUC5AC concentration (r = -0.183, P = 0.028).

172 ons of conjunctival goblet cell density with tear MUC5AC concentration and other ocular surface evalu

173 Tear MUC5AC concentration had significant positive corre

174 Tear MUC5AC concentration was quantified using enzyme-li

175 hirmer I test value, goblet cell density and tear MUC5AC concentration were significantly lower than

176 ease tear secretion, goblet cell density and tear MUC5AC concentration.

177 cts tear secretion, goblet cell density, and tear MUC5AC concentration.

178 e effect was pain (n = 17; 39%), followed by tearing (n = 10; 23%), photophobia (n = 6; 14%), itching

179 igate the effects of the Allergan Intranasal Tear Neurostimulator (ITN) on conjunctival goblet cell (

180 by design (i.e., topology) against cuts and tears: No matter how material is removed, either layer b

181 ainst those eyes with non-subsequent retinal tear (NSRT-retinal tear/s diagnosed at initial examinati

182 a specificity of 98.8% for partial-thickness tears; observed accuracy for full thickness tears was 98

183 tigate when retinal pigment epithelium (RPE) tears occur and their associated treatment patterns and

184 An anterior capsule tear occurred in 6 eyes, all of which had cataracts of n

185 the same segment, and in a single knee, the tear occurred in an adjacent segment.

186 erials is controlled largely by the wear and tear of everyday use, environmental stress and unexpecte

187 aging and differentiates aging from wear-and-tear of inanimate objects by deriving it from metabolism

188 relative severity of injuries up to physical tearing of tissue have been documented in clinical studi

189 ween US and MRI in detection of rotator cuff tears of any type (RCT) or FTT.

190 The concentration level of LCN1 in the tears of DR patients increases with DR severity.

191 ZIKAV could persist in the tears of infected patients for up to 30 days post-illnes

192 tected 28 complete- and 12 partial-thickness tears of the rotator cuff.

193 ncident acute PVD (and symptomatic horseshoe tears) offer a low cost and a favorable cost-utility (lo

194 tients were diagnosed as having rotator cuff tears on ultrasound (USG) and MRI.

195 s who had positive findings for rotator cuff tears on ultrasound and/or MRI were finally included in

196 uded eyes presenting one or multiple retinal tears only at initial examination (NSRT), and group 2 ey

197 corneal edema (n = 110, 0.53%), and retinal tear or detachment (n = 30, 0.14%).

198 9); 17.2% of patients had a previous retinal tear or retinal detachment in the fellow eye; mean numbe

199 The artificial tears or lubricants are the therapy most used for the tr

200 62.9 for geographic atrophy, hemorrhage, RPE tear, or scar (P < 0.0001).

201 endophthalmitis, sclerotomy-related retinal tears, or choroidal detachments were encountered in the

202 desiccating stress: significantly increased tear osmolarity (315.7 +/- 3.0 vs 327.7 +/- 5.1 mOsm/L,

203 ary outcome measures were mean change in (1) tear osmolarity and (2) DED symptoms (Ocular Surface Dis

204 ga-3 EFAs, for 3 months, resulted in reduced tear osmolarity and increased tear stability in people w

205 clera SCL treatment had a positive impact on tear osmolarity and van Bijsterveld score, as well as an

206 Ophthalmologists should consider evaluating tear osmolarity preoperatively, especially in highly dem

207 There was a significant decrease in tear osmolarity values (338.1 +/- 27.1 to 314.25 +/- 38.

208 Patients with tear osmolarity values of 312 mOsm/L or higher are more

209 The mean tear osmolarity values were, respectively, 305.63 +/- 15

210 At day 90, tear osmolarity was reduced from baseline with both kril

211 al hyperemia, tear film breakup time (TBUT), tear osmolarity, and the Symptom Assessment in Dry Eye (

212 ere performed before and after the exposure: tear osmolarity, phenol red thread test, conjunctival hy

213 Disease Index (OSDI) symptom questionnaire, tear osmolarity, Schirmer test, tear breakup time, conju

214 Dry eye signs were assessed by tear osmolarity, Schirmer test, tear breakup time, corne

215 Best-corrected visual acuity (BCVA), tear osmolarity, the Schirmer I test, tear film breakup

216 ive to protect the eyes and spread a film of tears over the cornea, but also on several socio-emotion

217 roplets and carry oil with them, causing the torn particles to be amphiphillic so that they contribut

218 nt in the fellow eye; mean number of retinal tears per eye 1.42 +/- 0.8 (range = 1-5); 20.8% presente

219 The mean number of retinal tears per eye was 1.36 +/- 0.5 (range = 1-2); bilateral

220 The other symptoms include tearing, photophobia and leukokoria.

221 The tear-producing lacrimal gland is a tubular organ that pr

222 ic socket sides showed a significantly lower tear production and higher tear drainage obstruction.

223 ignificant association between deficiency of tear production and LG volume reduction and agenesis.

224 There were compensatory increases in tear production but higher tear sodium and indexes of mu

225 re also was elevated corneal sensitivity and tear production in the treated corneas compared with veh

226 not incidental, and a thorough evaluation of tear production is recommended especially if ptosis surg

227 evaluated with slit-lamp biomicroscopy, and tear production quantified with the Schirmer test I.

228 ignificant decreases of corneal sensitivity, tear production, and epithelial subbasal nerve density w

229 hange in key clinical signs (tear stability, tear production, ocular surface staining, bulbar and lim

230 s, and viral or bacterial infections impairs tear production, the blinking reflex, and epithelial wou

231 s accurate with respect to partial thickness tears (PTT).

232 e was some evidence that the severe perineal tear rate was reduced in out-of-hours vaginal deliveries

233 SG) and MRI in the diagnosis of rotator cuff tears (RCT) and to determine if high resolution USG comp

234 Rotator cuff tears (RCTs) represent a significant proportion of shoul

235 Although membrane tears release soluble cytosolic contents, they are small

236 rollback and maintain flat slabs until slab tearing releases the overpressure.

237 Three patients used a tear replacement product (Systane) containing a polyquat

238 ereas treatment of an asymptomatic horseshoe tear resulted in $2981/QALY ($1436/QALY).

239 Treatment of a symptomatic horseshoe tear resulted in a net cost savings of $1749 ($1314) and

240 defects requiring cataract surgery; retinal tear; retinal detachment; retinal hemorrhages; scotomas;

241 blestone degeneration, retinal hole, retinal tear, rhegmatogenous retinal detachment, typical degener

242 mbined materials either separate or wear and tear, risking the exposure of an undesired material prop

243 Exclusion criteria included a full-thickness torn rotator cuff.

244 2 eyes that progressed to a further retinal tear/s (SRT) during follow-up.

245 th non-subsequent retinal tear (NSRT-retinal tear/s diagnosed at initial examination) formation.

246 detection within the physiological range for tear, saliva, and/or sweat.

247 Tear samples were collected from four volunteers, includ

248 e of the patterned FRET sensor to 2microL of tear samples.

249 bcutaneous injection of HC-HA/PTX3 preserved tear secretion and conjunctival goblet cell density and

250 keratopathy decreases corneal sensation and tear secretion and delays wound healing after injury.

251 Small-molecule CFTR activators increase tear secretion and prevent experimental dry eye disease.

252 ith or without total tarsorrhaphy, decreased tear secretion, and the loss of dendriform DCs at the oc

253 key signs of dry eye disease such as aqueous tear secretion, conjunctival goblet cells, epithelial co

254 We concluded that smoking might decrease tear secretion, goblet cell density and tear MUC5AC conc

255 to clarify whether cigarette smoking affects tear secretion, goblet cell density, and tear MUC5AC con

256 n the two cell types significantly increased tear secretion.

257 orarily decreased in weight and had impaired tear secretion.

258 elevated secretion and higher expression of tear secretory markers.

259 tory increases in tear production but higher tear sodium and indexes of mucin concentration in betaEN

260 ns care disinfecting solutions or artificial tear solutions containing polyquaternium-1.

261 analyze the prevalence of subsequent retinal tears (SRT) in patients with a PVD, and to identify poss

262 ted in reduced tear osmolarity and increased tear stability in people with DED.

263 included mean change in key clinical signs (tear stability, tear production, ocular surface staining

264 There was no significant difference in the tear strength of capsulotomies produced by manual CCC (m

265 The PPC edge tear strength was greater than that of FSLC for all 8 pa

266 The PPC tear strength was greater than that of manual CCC for al

267 Tear subduction re-establishes a continuous slab and all

268 Torn supraspinatus tendon (established pathology) and ma

269 o assess for joint subluxation, rotator cuff tears, tendinosis, subacromial-subdeltoid bursitis or ef

270 Adults aged >/=18 years with Schirmer tear test (without anesthesia) >/=1 and </=10 mm, cornea

271 The marked increase in NE in oGVHD tears that correlated strongly with elevated MMP-8, MMP-

272 ion from TG and subsequent virus shedding in tears that trigger recurrent corneal herpetic disease.

273 In the diagnosis of rotator cuff tears, the strength of agreement between ultrasound and

274 Asexual freshwater planarians reproduce by tearing themselves into two pieces by a process called b

275 h the lacrimal glands fail to produce enough tears to maintain a healthy ocular surface.

276 ieulafoy's lesions, and 4 with Mallory Weiss tears) to groups that underwent standard, visually guide

277 receive a bimatoprost insert plus artificial tears twice daily or a placebo insert plus timolol (0.5%

278 ients with clinically suspected rotator cuff tears underwent both ultrasound and MRI of the shoulder.

279 ogue scale [VAS]), and history of artificial tear use within 30 days of study entry.

280 ases were classified as having early or late tears using a segmented regression model.

281 us detachment (PVD) complicated with retinal tears using spectral domain optical coherence tomography

282 ivered topically, CFTRact-K089 doubled basal tear volume for 4 h and had no effect in CF mice.

283 al administration of 25 pmol of 12 increased tear volume in wild-type mice with sustained action for

284 0.1 nmol CFTRact-K089 3 times daily restored tear volume to basal levels, preventing corneal epitheli

285 surface staining, bulbar and limbal redness, tear volume, anterior blepharitis, meibomian gland cappi

286 hazard ratio for developing medial meniscal tear was 18.2 (95% confidence interval: 8.3, 39.8) if li

287 tears; observed accuracy for full thickness tears was 98.4% and 95.9% for partial thickness tears.

288 Tear wash fluid was collected from inferior fornix, and

289 einases (MMPs), and myeloperoxidase (MPO) in tear washes of patients with ocular graft-vs-host diseas

290 Tear washes were collected and analyzed for NE using a s

291 nsitivity, specificity, and accuracy for UCL tears were 81%, 91%, and 88%, respectively, and increase

292 Residual labral tears were detected in 35% of asymptomatic patients (six

293 .36 +/- 0.5 (range = 1-2); bilateral retinal tears were noted in 18.2% of eyes; 86.4% were myopic eye

294 Retinal pigment epithelial tears were seen in 95% of eyes in the bullous group and

295 6.23; P = 0.16); however, posterior capsular tears were significantly more common in FLACS versus MCS

296 MMP-9, and MPO levels were elevated in oGVHD tears when compared with controls (P < .0001).

297 nonenhanced MR imaging for diagnosis of SLAP tears, whereas 3-T MR imaging with or without intra-arti

298 tributable to geographic atrophy (GA) or RPE-tears with overlying preserved photoreceptor layers.

299 valuation of ulnar collateral ligament (UCL) tears with stress US, the interval gapping of the medial

300 The corresponding number of tears without prior finding of intrameniscal signal inte