ライフサイエンスコーパス: tear fluid

1 nds regulate the production and secretion of tear fluid.

2 9 activity assay in 1 microL of unstimulated tear fluid.

3 n composition and amount of O-glycans in the tear fluid.

4 icrobial peptides have been described in the tear fluid.

5 bead assay were used to quantify IL-1beta in tear fluid.

6 lm is also dictated by the amount of aqueous tear fluid.

7 ction between the lipid film and the aqueous tear fluid.

8 biologically inactive precursor IL-1 beta in tear fluid.

9 ace of the human eye and is present in human tear fluid.

10 human corneal epithelium and are present in tear fluid.

11 ase B (92 kDa) activity (P < 0.001) in their tear fluid.

12 ntrations in rosacea-affected than in normal tear fluids.

13 the average glucose concentrations found in tear fluid (0.15 mM).

14 sed by fluorometric measurement of collected tear fluid 15 minutes after instillation of 1% sodium fl

15 tective than tear fluid (80% protection with tear fluid, 48% with sulfacetamide).

16 t of tear fluid was less cytoprotective than tear fluid (80% protection with tear fluid, 48% with sul

17 neal surface caused by trapping bacteria and tear fluid against the cornea under the lens.

18 Nuclease deficiency in tear fluid allows eDNA and NETs to accumulate in precorn

19 on in both tear fluid and sulfacetamide, but tear fluid also blocked bacterial swimming motility.

20 Tear fluid also significantly reduced the severity of in

21 s cytokines in cultured CECs, its absence in tear fluid and CIC samples suggests that IL-1beta does n

22 y revealed bacterial chain formation in both tear fluid and sulfacetamide, but tear fluid also blocke

23 factant protein D (SP-D) is present in human tear fluid and that it can protect corneal epithelial ce

24 Tear fluid and the corneal epithelium combine to make a

25 pressed in the lacrimal gland, secreted into tear fluid, and detected only in primates.

26 rstanding of the interplay between bacteria, tear fluid, and the corneal epithelium that determines h

27 These cytokines were also measured in normal tear fluid before and after nasal stimulation to induce

28 opathy screening based on the examination of tear fluid biomarker changes.

29 e assumed to contribute to the production of tear fluid, but little is known about their function.

30 These data show that human tear fluid can protect against P. aeruginosa corneal inf

31 We tested the hypothesis that whole human tear fluid can protect corneal epithelia against P. aeru

32 These results suggest that human tear fluid can protect corneal epithelial cells against

33 Viable counts were performed on tear fluid collected at time points ranging from 3 to 14

34 ic, five invasive)/ml with or without reflex tear fluid collected from the conjunctival sacs of human

35 e was evaluated by measuring fluorescence in tear fluid collected from the inferior meniscus 15 minut

36 Immediately after tear fluid collection, conjunctival epithelium was obtai

37 s correlated with delayed tear clearance and tear fluid concentration of interleukin-1alpha, a proinf

38 We previously reported that human tear fluid could protect individual human corneal epithe

39 chia coli-induced travelers' diarrhea and in tear fluid derived from virally associated corneal disea

40 ion, even when inoculated ex vivo to exclude tear fluid effects.

41 sity of corneal fluorescein staining and the tear fluid IL-1 alpha concentration (r(2) = 0.17, P < 0.

42 Tear fluid IL-1beta and MMP-9 concentrations and the exp

43 omoter polymorphisms and TNF-alpha levels in tear fluid in scarring trachoma, a large matched-pair ca

44 sent study, we examined the effects of human tear fluid in vivo.

45 a, precursor IL-1 beta, and IL-1Ra in reflex tear fluid, indicating that the lacrimal glands may secr

46 WB assay, assessment of lactoferrin in human tear fluid is demonstrated with a goal of advancing towa

47 Boiled tear fluid lost bacteriostatic activity and effects on b

48 The tear fluid MMP-9 concentration increased in response to

49 Tear fluid nuclease activity was decreased significantly

50 amount of ocular surface eDNA and evaluated tear fluid nuclease activity.

51 ivity was evaluated by gelatin zymography in tear fluid obtained from 13 patients with ocular rosacea

52 IL-1 beta, was significantly elevated in the tear fluid of both dry-eye groups compared with normal s

53 els of IL-1beta protein were detected in the tear fluid of both groups.

54 mined whether nucleases are deficient in the tear fluid of dry eye disease (DED) patients, and whethe

55 se (MMP)-9 activity has been observed in the tear fluid of dry eye patients.

56 f the increased concentration of IL-1 in the tear fluid of patients with dry-eye disease.

57 MMP-3 was detected exclusively in the tear fluid of patients with ocular rosacea who had corne

58 The tear fluid of patients with Sjogren syndrome has reduced

59 cin MUC5AC were significantly reduced in the tear fluid of patients with Sjogren syndrome, corroborat

60 r concentration of pro-MMP-9 (92 kDa) in the tear fluid of rosacea patients than controls.

61 d levels of anti-MBP immunoglobulin A in the tear fluid of the immunized animals.

62 inoculation was performed ex vivo to exclude tear fluid or corneas were pretreated with EGTA to disru

63 he extracellular domain is released into the tear fluid or culture media.

64 r surface epithelia but is also found in the tear fluid, presumably in a soluble form, as found on th

65 Tear fluid retarded growth of only 50% of the P. aerugin

66 alomucin complex was immunoprecipitated from tear fluid samples and both corneal and conjunctival epi

67 ntagonist (IL-1Ra) were measured by ELISA in tear fluid samples obtained from normal individuals and

68 Conjunctival impression cytology and tear fluid samples were collected at baseline and after

69 nM, which when delivered topically increased tear fluid secretion in mice and showed efficacy in an e

70 In vivo pharmacokinetic studies in rabbit tear fluid showed significant increase in mean residence

71 In vitro, human tear fluid significantly reduced the ability of invasive

72 0.15 mM glucose concentrations in artificial tear fluid solution.

73 evealed that purified elastase could degrade tear fluid SP-D in vivo.

74 Dilution of tear fluid threefold significantly reduced cytoprotectio

75 Factors in tear fluid trigger keratocyte loss after removal of the

76 Tear fluid was collected at day 0 and day 7 visits, and

77 Unstimulated tear fluid was collected from patients with ocular rosac

78 Human tear fluid was collected from the inferior conjunctival

79 Tear fluid was collected from the inferior fornix of nor

80 Tear fluid was found to reduce the severity of disease w

81 on of IL-1 alpha and mature IL-1 beta in the tear fluid was increased, and the concentration of precu

82 ith bacteriostatic activity matching that of tear fluid was less cytoprotective than tear fluid (80%

83 Without perturbing the eyeball, 3 microL of tear fluid was sampled from the marginal conjunctiva und

84 concentrations of IL-1beta and TNF-alpha in tear fluid washings and in corneal and conjunctival epit

85 the concentrations of IL-1beta and MMP-9 in tear fluid washings and the concentrations of IL-1beta a

86 se (MMP)-9 concentration and activity in the tear fluid were evaluated with gelatin zymography and wi

87 human corneal epithelial cultures and human tear fluid were incubated with MMP-3.

88 ro-MMP-9 and IL-1alpha concentrations in the tear fluid were measured by enzyme-linked immunosorbent

89 Tear fluids were analyzed by microsphere-based immunoass

90 Treatment of the supernatant and tear fluid with MMP-3 resulted in two bands with molecul

91 e then inserted into the volume of collected tear fluids within the capillaries for detection.