ライフサイエンスコーパス: tectorial

1 that represent the transverse motions of the tectorial and basilar membranes within the organ of Cort

2 ar motion and endolymphatic flow between the tectorial membrane (TM) and reticular lamina (RL), is co

3 The tectorial membrane (TM) clearly plays a mechanical role

4 The tectorial membrane (TM) has a significantly larger stiff

5 However, genetic studies targeting the tectorial membrane (TM) have demonstrated both sharper a

6 were used to measure shear impedance of the tectorial membrane (TM) in two dimensions.

7 The solid component of the tectorial membrane (TM) is a porous matrix made up of th

8 The tectorial membrane (TM) is widely believed to play an im

9 The tectorial membrane (TM) of the mammalian cochlea is a co

10 relation and the pore radius of the isolated tectorial membrane (TM) of the mouse were determined.

11 altering the mechanical load applied by the tectorial membrane (TM) on the outer hair cell HB.

12 ent studies suggest that wave motions of the tectorial membrane (TM) play a critical role in determin

13 The tectorial membrane (TM) plays a key role in this process

14 e spatial extent and propagation velocity of tectorial membrane (TM) travelling waves and that these

15 The motion of the tectorial membrane (TM) with respect to the reticular la

16 In the Otoa(EGFP/EGFP) mouse, the tectorial membrane (TM), a ribbon-like strip of ECM that

17 is a modular, non-collagenous protein of the tectorial membrane (TM), an extracellular matrix of the

18 creted glycoproteins that are present in the tectorial membrane (TM), an extracellular structure over

19 , and DC shift on the basilar membrane (BM), tectorial membrane (TM), and OHC potentials are predicte

20 uency selectivity and wave properties of the tectorial membrane (TM).

21 the BM and another extracellular matrix, the tectorial membrane (TM).

22 the tips of the tallest stereocilia and the tectorial membrane (TM).

23 non-syndromic hearing loss, and suggest that tectorial membrane abnormalities may be one aetiology of

24 These mutants have tectorial membrane abnormalities, including a prominent

25 silar membrane, the radial vibrations of the tectorial membrane and reticular lamina were tuned.

26 structures that deflect the OHC bundle, the tectorial membrane and reticular lamina, to the transver

27 imulate the outer hair cell stereocilia, the tectorial membrane and reticular lamina, were sharply tu

28 ations, except in the narrow gap between the tectorial membrane and reticular lamina, where lubricati

29 ted to a reduction in the acting mass of the tectorial membrane and reveal a new function for this st

30 interactions between the organ of Corti, the tectorial membrane and the subtectorial fluid, and/or el

31 th (especially of the inner hair cells), the tectorial membrane appeared to be more resistant to post

32 stic trachea as well as the extension of the tectorial membrane are not correlated to the tonotopy.

33 , tip links are only sensitive to BAPTA, and tectorial membrane attachment crowns are removed by subt

34 nks appear around the base of the bundle and tectorial membrane attachment crowns are seen at the ste

35 s: tip links, horizontal top connectors, and tectorial membrane attachment crowns.

36 The radial stiffness of the tectorial membrane attachment was found to be a crucial

37 The tectorial membrane contains radially organized collagen

38 gap size between the IHC stereocilia and the tectorial membrane determine the characteristic frequenc

39 Combined with the changes in tectorial membrane dimensions from base to apex, the rad

40 Because the tectorial membrane directly overlies the inner hair cell

41 al workings of the organ of Corti and of the tectorial membrane have resisted exploration.

42 tically isolated a second major role for the tectorial membrane in hearing: it enables the motion of

43 s with electron-lucent cytoplasm; and 4) the tectorial membrane in the BWC papilla was narrow, coveri

44 r noncollagenous components of the mammalian tectorial membrane in the inner ear.

45 in a cross section of the organ of Corti and tectorial membrane in the mammalian cochlea, and quantif

46 ctorin (Tecta) is a major constituent of the tectorial membrane in the mammalian cochlea.

47 The tectorial membrane is an extracellular structure of the

48 ated in Tecta(C1509G/C1509G) mice, where the tectorial membrane is detached from OHC stereocilia, arg

49 micromechanics of the organ of Corti and the tectorial membrane is then analyzed by our new method.

50 band, when the hair bundle was loaded with a tectorial membrane mass.

51 a imprint pattern at the undersurface of the tectorial membrane may provide a way to detect possible

52 ngs are as follows: The reticular lamina and tectorial membrane move in unison with essentially no sq

53 l and Deiters cells and was deposited in the tectorial membrane of the cochlea between postnatal days

54 Electron microscopy of the tectorial membrane of these mice revealed loss of organi

55 ably form higher order structures with other tectorial membrane proteins such as alpha-tectorin and b

56 Inertial loading of a hair bundle by the tectorial membrane reduces the bundle's reactive load, a

57 the hemicochlea, we are able to show that a tectorial membrane stiffness gradient exists along the c

58 Unlike the natural situation where the tectorial membrane stimulates hair-cell stereocilia even

59 We found that the tectorial membrane sustains traveling wave propagation.

60 pared with basilar membrane traveling waves, tectorial membrane traveling waves have larger dynamic r

61 uted to decreases in spread of excitation of tectorial membrane traveling waves.

62 in the hair cell epithelium is distinct from tectorial membrane tuning.

63 ort, to our knowledge, the first measures of tectorial membrane vibration within the unopened cochlea

64 ere we show that the spread of excitation of tectorial membrane waves is similar in humans and mice,

65 ene mutation for alpha-tectorin indicate the tectorial membrane's key role in the mechanoelectrical t

66 abnormalities do not seriously influence the tectorial membrane's known role in ensuring that cochlea

67 mice with the Y1870C mutation in Tecta, the tectorial membrane's matrix structure is disrupted, and

68 e inner ear, direct experimental data on the tectorial membrane's physical properties are limited, an

69 of the outer hair cells are imbedded in the tectorial membrane, a sheet of extracellular matrix that

70 rin (encoded by Tecta) is a component of the tectorial membrane, an extracellular matrix of the cochl

71 beta-tectorin reveal multiple roles for the tectorial membrane, an extracellular matrix unique to th

72 ir bundles are not attached to the overlying tectorial membrane, are a notable exception.

73 ticular lamina greatly surpasses that of the tectorial membrane, giving rise to shear that deflects t

74 otion were hundreds of times larger than the tectorial membrane, reticular lamina (RL), and pillar ce

75 also exhibited obvious abnormalities in the tectorial membrane, supporting cells, and Reissner's mem

76 s similar in dead mice and in mice lacking a tectorial membrane.

77 chanical coupling of outer hair cells to the tectorial membrane.

78 hearing between the reticular lamina and the tectorial membrane.

79 ir cell stereocilia by mirroring them on the tectorial membrane.

80 als for precise collagen organisation in the tectorial membrane.

81 to produce fast lateral displacements of the tectorial membrane.

82 id-filled space between reticular lamina and tectorial membrane.

83 nd influences the physical properties of the tectorial membrane.

84 d graded mechanical properties of guinea pig tectorial membrane.

85 affects interactions of stereocilia with the tectorial membrane.

86 and sensory epithelium, and deformity of the tectorial membrane.

87 mechanical link of outer hair cells with the tectorial membrane.

88 lia to maintain stable interactions with the tectorial membrane.

89 ilar membrane, the reticular lamina, and the tectorial membrane.

90 lear partition upon tip-link destruction and tectorial-membrane removal, suggesting that these struct

91 real cochlea, the motions of the basilar and tectorial membranes are fundamentally different during i

92 In cochlear sections of Ceacam16(-/-) mice tectorial membranes were significantly more often stretc

93 of Corti sandwiched between the basilar and tectorial membranes, contains the outer hair cells that

94 r matrices, including otoconial, cupular and tectorial membranes, in Oc90 null mice, likely due to an

95 chlear resonance, presumably the basilar and tectorial membranes, move together in phase during the o

96 mited, and only a few direct measurements on tectorial micromechanics are available.